JP2023113681A5 - - Google Patents
Info
- Publication number
- JP2023113681A5 JP2023113681A5 JP2023080568A JP2023080568A JP2023113681A5 JP 2023113681 A5 JP2023113681 A5 JP 2023113681A5 JP 2023080568 A JP2023080568 A JP 2023080568A JP 2023080568 A JP2023080568 A JP 2023080568A JP 2023113681 A5 JP2023113681 A5 JP 2023113681A5
- Authority
- JP
- Japan
- Prior art keywords
- methods
- new products
- manufacturing methods
- manufacturing
- methods substantially
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762527744P | 2017-06-30 | 2017-06-30 | |
| US62/527,744 | 2017-06-30 | ||
| US201862653436P | 2018-04-05 | 2018-04-05 | |
| US62/653,436 | 2018-04-05 | ||
| US201862673064P | 2018-05-17 | 2018-05-17 | |
| US62/673,064 | 2018-05-17 | ||
| PCT/US2018/040286 WO2019006299A1 (en) | 2017-06-30 | 2018-06-29 | COMPOSITIONS AND METHODS FOR THE USE OF 2- (4-CHLOROPHENYL) -N - ((2- (2,6-DIOXOPIPERIDIN-3-YL) -1-OXOISOINDOLIN-5-YL) METHYL) -2,2-DIFLUOROACETAMIDE |
| JP2019572475A JP2020526501A (ja) | 2017-06-30 | 2018-06-29 | ２−（４−クロロフェニル）−ｎ−｛［２−（２，６−ジオキソピペリジン−３−イル）−１−オキソイソインドリン−５−イル］メチル｝−２，２−ジフルオロアセトアミドの組成物及び使用法 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019572475A Division JP2020526501A (ja) | 2017-06-30 | 2018-06-29 | ２−（４−クロロフェニル）−ｎ−｛［２−（２，６−ジオキソピペリジン−３−イル）−１−オキソイソインドリン−５−イル］メチル｝−２，２−ジフルオロアセトアミドの組成物及び使用法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023113681A JP2023113681A (ja) | 2023-08-16 |
| JP2023113681A5 true JP2023113681A5 (https=) | 2026-01-15 |
Family
ID=64741897
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019572475A Pending JP2020526501A (ja) | 2017-06-30 | 2018-06-29 | ２−（４−クロロフェニル）−ｎ−｛［２−（２，６−ジオキソピペリジン−３−イル）−１−オキソイソインドリン−５−イル］メチル｝−２，２−ジフルオロアセトアミドの組成物及び使用法 |
| JP2023080568A Pending JP2023113681A (ja) | 2017-06-30 | 2023-05-16 | ２－（４－クロロフェニル）－ｎ－｛［２－（２，６－ジオキソピペリジン－３－イル）－１－オキソイソインドリン－５－イル］メチル｝－２，２－ジフルオロアセトアミドの組成物及び使用法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019572475A Pending JP2020526501A (ja) | 2017-06-30 | 2018-06-29 | ２−（４−クロロフェニル）−ｎ−｛［２−（２，６−ジオキソピペリジン−３−イル）−１−オキソイソインドリン−５−イル］メチル｝−２，２−ジフルオロアセトアミドの組成物及び使用法 |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US20190030018A1 (https=) |
| EP (2) | EP3644999B1 (https=) |
| JP (2) | JP2020526501A (https=) |
| KR (1) | KR20200020899A (https=) |
| CN (1) | CN111032043A (https=) |
| AU (1) | AU2018294327A1 (https=) |
| BR (1) | BR112019028101A2 (https=) |
| CA (1) | CA3068591A1 (https=) |
| CL (1) | CL2019003857A1 (https=) |
| DK (1) | DK3644999T3 (https=) |
| ES (1) | ES2939739T3 (https=) |
| FI (1) | FI3644999T3 (https=) |
| HR (1) | HRP20230210T1 (https=) |
| HU (1) | HUE061356T2 (https=) |
| IL (1) | IL271726A (https=) |
| LT (1) | LT3644999T (https=) |
| MX (2) | MX2019015886A (https=) |
| PL (1) | PL3644999T3 (https=) |
| PT (1) | PT3644999T (https=) |
| RS (1) | RS64029B1 (https=) |
| SG (1) | SG11201913008TA (https=) |
| SI (1) | SI3644999T1 (https=) |
| SM (1) | SMT202300068T1 (https=) |
| WO (1) | WO2019006299A1 (https=) |
| ZA (1) | ZA201908605B (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2018276611B2 (en) | 2017-05-31 | 2022-01-06 | Taiho Pharmaceutical Co., Ltd. | Method for predicting therapeutic effect of LSD1 inhibitor based on expression of INSM1 |
| FI3908281T3 (fi) * | 2019-01-09 | 2024-10-01 | Celgene Corp | Antiproliferatiivisia yhdisteitä ja toisia aktiivisia aineita käytettäväksi multippelin myelooman hoidossa |
| JP2022537551A (ja) | 2019-06-20 | 2022-08-26 | セルジーン・クオンティセル・リサーチ・インコーポレイテッド | ベネトクラクス、ギルテリチニブ、ミドスタウリン、または白血病もしくは骨髄異形成症候群を治療するための他の化合物との組み合わせにおけるアザシチジン |
| WO2021086829A1 (en) * | 2019-10-28 | 2021-05-06 | Celgene Corporation | Methods for treating leukemia and use of a leukemic stem cell signature to predict clinical sensitivity to therapies |
| WO2021086830A1 (en) * | 2019-10-28 | 2021-05-06 | Celgene Corporation | Use of biomarkers to predict clinical sensitivity to 2-(4-chlorophenyl)-n-((2-(2,6-dioxopiperidin-3-yl)-1- oxoisoindolin-5-yl)methyl)-2,2-difluoroacetamide |
| WO2021095835A1 (en) * | 2019-11-13 | 2021-05-20 | Taiho Pharmaceutical Co., Ltd. | Novel salt of terphenyl compound |
| EP4121051A4 (en) * | 2020-03-16 | 2024-04-17 | Celgene Corporation | COMBINATION THERAPY FOR ACUTE MYELOID LEUKEMIA |
| JP2023545274A (ja) * | 2020-10-07 | 2023-10-27 | クルゲン（シャンハイ），インク． | 癌を処置する化合物および方法 |
| AU2022207648A1 (en) | 2021-01-13 | 2023-07-27 | Monte Rosa Therapeutics Ag | Isoindolinone compounds |
| CN113125602A (zh) * | 2021-04-16 | 2021-07-16 | 山东铂源药业有限公司 | 一种哌柏西利中残留溶剂的检测方法 |
| WO2024015855A1 (en) * | 2022-07-13 | 2024-01-18 | Monte Rosa Therapeutics, Inc. | COMBINATION THERAPY COMPRISING GSPT1-DIRECTED MOLECULAR GLUE DEGRADERS AND PI3K/AKT/mTOR PATHWAY INHIBITORS |
| TW202423434A (zh) * | 2022-10-07 | 2024-06-16 | 瑞士商歐庫利斯營運股份有限公司 | mTOR抑制劑的點眼劑微懸液 |
| US12357645B2 (en) | 2023-03-09 | 2025-07-15 | Minneamrita Therapeutics Llc | Drug combination for treatment of gastric cancer |
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| EP0011312A1 (en) | 1977-07-09 | 1980-05-28 | LUCAS INDUSTRIES public limited company | Road vehicle electrical systems |
| DE2848746A1 (de) | 1978-11-10 | 1980-05-22 | Wolfgang Arheiliger | Dichtung fuer eine schwellenlose tuere mit drehfluegel |
| DE3346123A1 (de) * | 1983-12-21 | 1985-06-27 | Janssen Pharmaceutica, N.V., Beerse | Pharmazeutische praeparate von in wasser schwerloeslichen oder instabilen arzneistoffen und verfahren zu ihrer herstellung |
| US5391485A (en) | 1985-08-06 | 1995-02-21 | Immunex Corporation | DNAs encoding analog GM-CSF molecules displaying resistance to proteases which cleave at adjacent dibasic residues |
| US4810643A (en) | 1985-08-23 | 1989-03-07 | Kirin- Amgen Inc. | Production of pluripotent granulocyte colony-stimulating factor |
| JPS63500636A (ja) | 1985-08-23 | 1988-03-10 | 麒麟麦酒株式会社 | 多分化能性顆粒球コロニー刺激因子をコードするｄｎａ |
| US6352694B1 (en) | 1994-06-03 | 2002-03-05 | Genetics Institute, Inc. | Methods for inducing a population of T cells to proliferate using agents which recognize TCR/CD3 and ligands which stimulate an accessory molecule on the surface of the T cells |
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| GB9126209D0 (en) * | 1991-12-10 | 1992-02-12 | Orion Yhtymae Oy | Drug formulations for parenteral use |
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| US5855887A (en) | 1995-07-25 | 1999-01-05 | The Regents Of The University Of California | Blockade of lymphocyte down-regulation associated with CTLA-4 signaling |
| US6051227A (en) | 1995-07-25 | 2000-04-18 | The Regents Of The University Of California, Office Of Technology Transfer | Blockade of T lymphocyte down-regulation associated with CTLA-4 signaling |
| US5811097A (en) | 1995-07-25 | 1998-09-22 | The Regents Of The University Of California | Blockade of T lymphocyte down-regulation associated with CTLA-4 signaling |
| US5948893A (en) | 1996-01-17 | 1999-09-07 | The United States Of America As Represented By The Secretary Of The Navy | Murine hybridoma and antibody binding to CD28 receptor secreted by the hybridoma and method of using the antibody |
| US6207157B1 (en) | 1996-04-23 | 2001-03-27 | The United States Of America As Represented By The Department Of Health And Human Services | Conjugate vaccine for nontypeable Haemophilus influenzae |
| US6682736B1 (en) | 1998-12-23 | 2004-01-27 | Abgenix, Inc. | Human monoclonal antibodies to CTLA-4 |
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| CN105593215B (zh) | 2013-07-11 | 2019-01-15 | 安吉奥斯医药品有限公司 | 用于治疗癌症的作为idh2突变体抑制剂的2,4-或4,6-二氨基嘧啶化合物 |
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| AU2014295938B2 (en) | 2013-08-02 | 2018-07-19 | Les Laboratoires Servier | Therapeutically active compounds and their methods of use |
| TW201540323A (zh) * | 2014-01-15 | 2015-11-01 | Celgene Corp | ３－（５－胺基－２－甲基－４－側氧基－４ｈ－喹唑啉－３－基）－哌啶－２，６－二酮之調配物 |
| US9499514B2 (en) | 2014-07-11 | 2016-11-22 | Celgene Corporation | Antiproliferative compounds and methods of use thereof |
| WO2017120415A1 (en) | 2016-01-08 | 2017-07-13 | Celgene Corporation | Solid forms of 2-(4-chlorophenyl)-n-((2-2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-5-yl) methyl)-2,2-difluoroacetamide, and their pharmaceutical compositions and uses |
| CN108601777B (zh) * | 2016-01-08 | 2021-08-03 | 细胞基因公司 | 2-(4-氯苯基)-n-((2-(2,6-二氧代哌啶-3-基)-1-氧代异吲哚啉-5-基)甲基)-2,2-二氟乙酰胺的制剂 |
-
2018
- 2018-06-29 KR KR1020207002231A patent/KR20200020899A/ko not_active Withdrawn
- 2018-06-29 US US16/024,581 patent/US20190030018A1/en not_active Abandoned
- 2018-06-29 WO PCT/US2018/040286 patent/WO2019006299A1/en not_active Ceased
- 2018-06-29 DK DK18823719.2T patent/DK3644999T3/da active
- 2018-06-29 AU AU2018294327A patent/AU2018294327A1/en not_active Abandoned
- 2018-06-29 LT LTEPPCT/US2018/040286T patent/LT3644999T/lt unknown
- 2018-06-29 CN CN201880056213.2A patent/CN111032043A/zh active Pending
- 2018-06-29 CA CA3068591A patent/CA3068591A1/en active Pending
- 2018-06-29 SG SG11201913008TA patent/SG11201913008TA/en unknown
- 2018-06-29 MX MX2019015886A patent/MX2019015886A/es unknown
- 2018-06-29 ES ES18823719T patent/ES2939739T3/es active Active
- 2018-06-29 RS RS20230153A patent/RS64029B1/sr unknown
- 2018-06-29 SI SI201830859T patent/SI3644999T1/sl unknown
- 2018-06-29 HR HRP20230210TT patent/HRP20230210T1/hr unknown
- 2018-06-29 FI FIEP18823719.2T patent/FI3644999T3/fi active
- 2018-06-29 EP EP18823719.2A patent/EP3644999B1/en active Active
- 2018-06-29 JP JP2019572475A patent/JP2020526501A/ja active Pending
- 2018-06-29 PT PT188237192T patent/PT3644999T/pt unknown
- 2018-06-29 EP EP22212562.7A patent/EP4201399A3/en not_active Withdrawn
- 2018-06-29 PL PL18823719.2T patent/PL3644999T3/pl unknown
- 2018-06-29 BR BR112019028101-0A patent/BR112019028101A2/pt not_active Application Discontinuation
- 2018-06-29 SM SM20230068T patent/SMT202300068T1/it unknown
- 2018-06-29 HU HUE18823719A patent/HUE061356T2/hu unknown
-
2019
- 2019-12-20 MX MX2022001410A patent/MX2022001410A/es unknown
- 2019-12-23 ZA ZA2019/08605A patent/ZA201908605B/en unknown
- 2019-12-26 CL CL2019003857A patent/CL2019003857A1/es unknown
- 2019-12-26 IL IL271726A patent/IL271726A/en unknown
-
2023
- 2023-05-16 JP JP2023080568A patent/JP2023113681A/ja active Pending