JP2023029957A5 - - Google Patents
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- JP2023029957A5 JP2023029957A5 JP2022193738A JP2022193738A JP2023029957A5 JP 2023029957 A5 JP2023029957 A5 JP 2023029957A5 JP 2022193738 A JP2022193738 A JP 2022193738A JP 2022193738 A JP2022193738 A JP 2022193738A JP 2023029957 A5 JP2023029957 A5 JP 2023029957A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- pharmaceutically acceptable
- acceptable salt
- polypeptide
- salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662428492P | 2016-11-30 | 2016-11-30 | |
| US62/428,492 | 2016-11-30 | ||
| US201762553313P | 2017-09-01 | 2017-09-01 | |
| US62/553,313 | 2017-09-01 | ||
| JP2019529240A JP7649624B2 (ja) | 2016-11-30 | 2017-11-30 | 副甲状腺ホルモン受容体刺激を介する、骨折をターゲティングした骨再生 |
| PCT/US2017/064081 WO2018102616A1 (en) | 2016-11-30 | 2017-11-30 | Fracture targeted bone regeneration through parathyroid hormone receptor stimulation |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019529240A Division JP7649624B2 (ja) | 2016-11-30 | 2017-11-30 | 副甲状腺ホルモン受容体刺激を介する、骨折をターゲティングした骨再生 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023029957A JP2023029957A (ja) | 2023-03-07 |
| JP2023029957A5 true JP2023029957A5 (OSRAM) | 2023-07-28 |
Family
ID=62241919
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019529240A Active JP7649624B2 (ja) | 2016-11-30 | 2017-11-30 | 副甲状腺ホルモン受容体刺激を介する、骨折をターゲティングした骨再生 |
| JP2022193738A Pending JP2023029957A (ja) | 2016-11-30 | 2022-12-02 | 副甲状腺ホルモン受容体刺激を介する、骨折をターゲティングした骨再生 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019529240A Active JP7649624B2 (ja) | 2016-11-30 | 2017-11-30 | 副甲状腺ホルモン受容体刺激を介する、骨折をターゲティングした骨再生 |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US20200317745A1 (OSRAM) |
| EP (1) | EP3548012A4 (OSRAM) |
| JP (2) | JP7649624B2 (OSRAM) |
| CN (1) | CN110114065A (OSRAM) |
| AU (1) | AU2017367699B2 (OSRAM) |
| BR (1) | BR112019011070A2 (OSRAM) |
| CA (1) | CA3045458A1 (OSRAM) |
| IL (1) | IL266977B2 (OSRAM) |
| MX (1) | MX2019006189A (OSRAM) |
| WO (1) | WO2018102616A1 (OSRAM) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112019011070A2 (pt) * | 2016-11-30 | 2019-10-01 | Purdue Research Foundation | regeneração óssea direcionada à fratura através da estimulação do receptor de hormônio da paratireoide |
| EP3790574A4 (en) | 2018-05-30 | 2022-07-13 | Purdue Research Foundation | TARGETING ANABOLIC DRUGS TO ACCELERATE FRACTURE REPAIR |
| CN110551201B (zh) * | 2019-08-26 | 2020-04-28 | 杭州彗搏科技有限公司 | 一种新型骨形成蛋白2来源的环肽、制备方法及其应用 |
| EP4027899A4 (en) * | 2019-09-12 | 2023-08-16 | Radius Health, Inc. | METHODS OF ENHANCING SPINE FUSION USING ABALOPARATIDE |
| CN112646042A (zh) * | 2019-10-10 | 2021-04-13 | 陕西麦科奥特科技有限公司 | 活性多肽化合物 |
| CN116848146A (zh) * | 2020-09-03 | 2023-10-03 | I·S·Y·陈 | 可溶性碱性磷酸酶构建体和包含编码可溶性碱性磷酸酶构建体的多核苷酸的表达载体 |
| MX2023004796A (es) * | 2020-10-26 | 2023-07-18 | Purdue Research Foundation | Compuestos, composiciones y metodos de uso para tratar fracturas oseas. |
| US20230390363A1 (en) * | 2020-10-26 | 2023-12-07 | Purdue Research Foundation | Compounds, Compositions and Methods of Use to Treat Spinal Fusions |
| WO2022149066A1 (en) * | 2021-01-05 | 2022-07-14 | Radius Health, Inc. | Treatment of long bone fractures with abaloparatide |
| US20250295725A1 (en) * | 2022-01-14 | 2025-09-25 | Purdue Research Foundation | Bone targeted treatment in osteogenesis imperfecta |
| WO2024246840A1 (en) * | 2023-06-01 | 2024-12-05 | Radius Health, Inc. | Methods for identification and quantitation of abaloparatide and related peptide impurities |
| WO2025019691A1 (en) * | 2023-07-19 | 2025-01-23 | Zymeron Corporation | Drug conjugates for bone marrow protection |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2098283A1 (en) * | 1990-12-21 | 1992-06-22 | Richard P. Bozzato | Oxidation resistant variants of parathyroid hormone |
| WO1995002610A1 (en) * | 1993-07-13 | 1995-01-26 | Syntex (U.S.A.) Inc. | Analogs of parathyroid hormone and parathyroid hormone related peptide: synthesis and use for the treatment of osteoporosis |
| AU757658B2 (en) * | 1998-03-09 | 2003-02-27 | Zealand Pharma A/S | Pharmacologically active peptide conjugates having a reduced tendency towards enzymatic hydrolysis |
| US7057012B1 (en) * | 1998-12-31 | 2006-06-06 | The General Hospital Corporation | PTH functional domain conjugate peptides, derivatives thereof and novel tethered ligand-receptor molecules |
| JP2000327583A (ja) * | 1999-05-17 | 2000-11-28 | Medei Sci Puraningu:Kk | 骨指向性ホルモン誘導体 |
| WO2004062588A2 (en) * | 2003-01-06 | 2004-07-29 | University Of Utah | Water-soluble polymeric bone-targeting drug delivery system |
| PL2348114T3 (pl) * | 2004-04-21 | 2019-08-30 | Alexion Pharmaceuticals, Inc. | Koniugaty do dostarczania do kości i sposób ich wykorzystania do nakierowywania białek na kość |
| US7863238B2 (en) * | 2004-06-10 | 2011-01-04 | Saint Louis University | Proteins with an attached short peptide of acidic amino acids |
| US20110046059A1 (en) * | 2005-09-06 | 2011-02-24 | Zelos Therapeutics, Inc. | Pharmaceutically acceptable formulations/compositions for peptidyl drugs |
| US7803770B2 (en) * | 2006-10-03 | 2010-09-28 | Radius Health, Inc. | Method of treating osteoporosis comprising administration of PTHrP analog |
| CA2664734C (en) * | 2006-10-03 | 2023-08-01 | Radius Health, Inc. | Method of drug delivery for bone anabolic protein |
| ES2675174T3 (es) * | 2007-04-09 | 2018-07-09 | The Board Of Trustees Of The University Of Arkansas | Proteínas de fusión de un dominio de enlazamiento a colágeno y hormona paratiroidea |
| RS53302B (sr) * | 2007-05-11 | 2014-08-29 | Alexion Pharma Holding | Alkalna fosfataza koja je usmerena na kosti, pribor i postupci upotrebe |
| EP2303288A4 (en) * | 2008-05-22 | 2015-04-22 | Univ Ramot | CONJUGATES OF A POLYMER, A BISPHOSPHONATE AND AN ANTI-ANGIOGENESE MEDIUM AND ITS USE IN THE TREATMENT AND CONTROL OF ILLNESSES RELATED TO BONE |
| WO2012111852A1 (ja) * | 2011-02-17 | 2012-08-23 | 帝人ファーマ株式会社 | 椎体骨折治療剤及びその評価方法 |
| SG194570A1 (en) * | 2011-04-22 | 2013-12-30 | Radius Health Inc | Method of drug delivery for pth, pthrp and related peptides |
| CN102824647B (zh) * | 2011-06-13 | 2014-07-23 | 香港中文大学 | 基于小核酸药物成骨治疗的骨靶向递送系统及其制备方法 |
| CA2883707A1 (en) * | 2012-08-28 | 2014-03-06 | The Governors Of The University Of Alberta | Parathyroid hormone, insulin, and related peptides conjugated to bone targeting moieties and methods of making and using thereof |
| EP3016674A4 (en) * | 2013-06-23 | 2017-03-15 | Wisconsin Alumni Research Foundation | Alpha-/beta-polypeptide analogs of parathyroid hormone (pth) and method of using same |
| WO2016141250A1 (en) * | 2015-03-03 | 2016-09-09 | Radius Health, Inc. | USES OF PTHrP ANALOGUE IN REDUCING FRACTURE RISK |
| US10279044B2 (en) * | 2015-05-29 | 2019-05-07 | Purdue Research Foundation | Bone fracture repair by targeting of agents that promote bone healing |
| CN106039316B (zh) * | 2016-05-03 | 2019-04-02 | 同济大学 | 一种基于多肽构建的成骨细胞靶向载体及其制备与应用 |
| BR112019011070A2 (pt) * | 2016-11-30 | 2019-10-01 | Purdue Research Foundation | regeneração óssea direcionada à fratura através da estimulação do receptor de hormônio da paratireoide |
| MX2023004796A (es) * | 2020-10-26 | 2023-07-18 | Purdue Research Foundation | Compuestos, composiciones y metodos de uso para tratar fracturas oseas. |
-
2017
- 2017-11-30 BR BR112019011070-4A patent/BR112019011070A2/pt active Search and Examination
- 2017-11-30 IL IL266977A patent/IL266977B2/en unknown
- 2017-11-30 JP JP2019529240A patent/JP7649624B2/ja active Active
- 2017-11-30 MX MX2019006189A patent/MX2019006189A/es unknown
- 2017-11-30 US US16/464,164 patent/US20200317745A1/en not_active Abandoned
- 2017-11-30 AU AU2017367699A patent/AU2017367699B2/en active Active
- 2017-11-30 EP EP17875427.1A patent/EP3548012A4/en active Pending
- 2017-11-30 CA CA3045458A patent/CA3045458A1/en active Pending
- 2017-11-30 WO PCT/US2017/064081 patent/WO2018102616A1/en not_active Ceased
- 2017-11-30 CN CN201780073942.4A patent/CN110114065A/zh active Pending
-
2020
- 2020-03-31 US US16/836,366 patent/US10960054B2/en active Active
-
2021
- 2021-02-24 US US17/184,400 patent/US20210283227A1/en active Pending
-
2022
- 2022-12-02 JP JP2022193738A patent/JP2023029957A/ja active Pending
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