JP2022554389A5 - - Google Patents
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- Publication number
- JP2022554389A5 JP2022554389A5 JP2022526326A JP2022526326A JP2022554389A5 JP 2022554389 A5 JP2022554389 A5 JP 2022554389A5 JP 2022526326 A JP2022526326 A JP 2022526326A JP 2022526326 A JP2022526326 A JP 2022526326A JP 2022554389 A5 JP2022554389 A5 JP 2022554389A5
- Authority
- JP
- Japan
- Prior art keywords
- substituted
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- independently selected
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025117223A JP2025148482A (ja) | 2019-11-05 | 2025-07-11 | 炎症性障害を治療するためのＭｒｇｐｒＸ２アンタゴニスト |
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962931183P | 2019-11-05 | 2019-11-05 | |
| US62/931,183 | 2019-11-05 | ||
| US201962931698P | 2019-11-06 | 2019-11-06 | |
| US62/931,698 | 2019-11-06 | ||
| US202063046461P | 2020-06-30 | 2020-06-30 | |
| US63/046,461 | 2020-06-30 | ||
| PCT/US2020/059201 WO2021092240A1 (en) | 2019-11-05 | 2020-11-05 | Mrgprx2 antagonists for the treatment of inflammatory disorders |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025117223A Division JP2025148482A (ja) | 2019-11-05 | 2025-07-11 | 炎症性障害を治療するためのＭｒｇｐｒＸ２アンタゴニスト |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022554389A JP2022554389A (ja) | 2022-12-28 |
| JP2022554389A5 true JP2022554389A5 (https=) | 2024-05-21 |
| JP7712922B2 JP7712922B2 (ja) | 2025-07-24 |
Family
ID=73646519
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022526326A Active JP7712922B2 (ja) | 2019-11-05 | 2020-11-05 | 炎症性障害を治療するためのＭｒｇｐｒＸ２アンタゴニスト |
| JP2025117223A Pending JP2025148482A (ja) | 2019-11-05 | 2025-07-11 | 炎症性障害を治療するためのＭｒｇｐｒＸ２アンタゴニスト |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025117223A Pending JP2025148482A (ja) | 2019-11-05 | 2025-07-11 | 炎症性障害を治療するためのＭｒｇｐｒＸ２アンタゴニスト |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US20230029266A1 (https=) |
| EP (1) | EP4054554A1 (https=) |
| JP (2) | JP7712922B2 (https=) |
| CN (1) | CN114845709B (https=) |
| AU (1) | AU2020380395A1 (https=) |
| CA (1) | CA3159766A1 (https=) |
| IL (1) | IL292690A (https=) |
| WO (1) | WO2021092240A1 (https=) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2019533022A (ja) | 2016-10-24 | 2019-11-14 | ユマニティ セラピューティクス，インコーポレーテッド | 化合物及びその使用 |
| EP3566055B1 (en) | 2017-01-06 | 2025-03-12 | Janssen Pharmaceutica NV | Scd inhibitor for the treatment of neurological disorders |
| CA3083000A1 (en) | 2017-10-24 | 2019-05-02 | Yumanity Therapeutics, Inc. | Compounds and uses thereof |
| WO2019183587A1 (en) | 2018-03-23 | 2019-09-26 | Yumanity Therapeutics, Inc. | Compounds and uses thereof |
| WO2020154571A1 (en) | 2019-01-24 | 2020-07-30 | Yumanity Therapeutics, Inc. | Compounds and uses thereof |
| WO2021092240A1 (en) | 2019-11-05 | 2021-05-14 | Dermira, Inc. | Mrgprx2 antagonists for the treatment of inflammatory disorders |
| EA202192047A1 (ru) | 2019-11-13 | 2021-12-08 | Юманити Терапьютикс, Инк. | Соединения и их применение |
| TWI904906B (zh) | 2020-08-24 | 2025-11-11 | 美商達薩瑪治療公司 | Sarm1之抑制劑 |
| US12084453B2 (en) | 2021-12-10 | 2024-09-10 | Incyte Corporation | Bicyclic amines as CDK12 inhibitors |
| WO2023111996A1 (en) | 2021-12-17 | 2023-06-22 | Reglagene Holding, Inc. | Compositions and methods of making and using small molecules in the treatment of cancer |
| US12215102B2 (en) | 2023-02-28 | 2025-02-04 | Reglagene, Inc. | Compositions and methods for making and using small molecules for tubulin-targeted therapy in the treatment of cancers and related conditions |
| WO2025002360A1 (zh) * | 2023-06-30 | 2025-01-02 | 北京普祺医药科技股份有限公司 | 一种mrgprx2拮抗剂、药物组合物以及其用途 |
| WO2025042736A1 (en) | 2023-08-18 | 2025-02-27 | Incyte Corporation | Bicyclic heterocycles as mrgprx2 antagonists |
| WO2025066935A1 (en) * | 2023-09-28 | 2025-04-03 | Hepaitech (Beijing) Biopharma Technology Co., Ltd. | Compounds, compositions and methods thereof |
| WO2025130765A1 (en) * | 2023-12-18 | 2025-06-26 | Hepaitech (Beijing) Biopharma Technology Co., Ltd. | Compounds, compositions and methods thereof |
| WO2025160430A1 (en) | 2024-01-25 | 2025-07-31 | Incyte Corporation | Bicyclic heterocycles as mrgprx2 antagonists |
| KR20250121245A (ko) * | 2024-02-02 | 2025-08-12 | 삼진제약주식회사 | MRGPRX2 (Mas-related G-protein coupled receptor member X2) 길항제로서 신규 화합물 및 이를 포함하는 약학적 조성물 |
| WO2025222040A1 (en) | 2024-04-19 | 2025-10-23 | Escient Pharmaceuticals, Inc. | Mrgprx2 modulators for use in treating mrgprx2 dependent conditions in subjects with low ige |
| JP2026009006A (ja) * | 2024-07-01 | 2026-01-19 | 日本たばこ産業株式会社 | ピリダジノン化合物及びその医薬用途 |
| WO2026035726A1 (en) * | 2024-08-07 | 2026-02-12 | Arcus Biosciences, Inc. | Piperidylurea compounds and methods of use thereof |
| US12612396B1 (en) * | 2024-11-20 | 2026-04-28 | Dewpoint Therapeutics, Inc. | Modulators of beta catenin and uses thereof |
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| WO2021092240A1 (en) | 2019-11-05 | 2021-05-14 | Dermira, Inc. | Mrgprx2 antagonists for the treatment of inflammatory disorders |
| CN114901280B (zh) | 2019-11-05 | 2025-05-27 | 德米拉公司 | MrgprX2拮抗剂及其用途 |
-
2020
- 2020-11-05 WO PCT/US2020/059201 patent/WO2021092240A1/en not_active Ceased
- 2020-11-05 US US17/772,467 patent/US20230029266A1/en active Pending
- 2020-11-05 CN CN202080087623.0A patent/CN114845709B/zh active Active
- 2020-11-05 EP EP20816766.8A patent/EP4054554A1/en active Pending
- 2020-11-05 AU AU2020380395A patent/AU2020380395A1/en active Pending
- 2020-11-05 JP JP2022526326A patent/JP7712922B2/ja active Active
- 2020-11-05 CA CA3159766A patent/CA3159766A1/en active Pending
-
2022
- 2022-05-02 IL IL292690A patent/IL292690A/en unknown
-
2024
- 2024-10-22 US US18/923,566 patent/US12502380B2/en active Active
-
2025
- 2025-07-11 JP JP2025117223A patent/JP2025148482A/ja active Pending
- 2025-10-03 US US19/349,768 patent/US20260027089A1/en active Pending
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