|
GB9720465D0
(en)
|
1997-09-25 |
1997-11-26 |
Oxford Biomedica Ltd |
Dual-virus vectors
|
|
US6436392B1
(en)
|
1998-05-20 |
2002-08-20 |
University Of Iowa Research Foundation |
Adeno-associated virus vectors
|
|
CA2386546A1
(en)
|
1999-10-07 |
2001-04-12 |
University Of Iowa Research Foundation |
Adeno-associated viruses and uses thereof
|
|
WO2001029243A1
(en)
|
1999-10-15 |
2001-04-26 |
Dalhousie University |
Method and vector for producing and transferring trans-spliced peptides
|
|
AU4445701A
(en)
|
2000-03-24 |
2001-10-03 |
Centre National De La Recherche Scientifique-Cnrs |
Multiple human and mouse otoferlin isoforms
|
|
US20040072154A1
(en)
|
2000-12-22 |
2004-04-15 |
Morris David W. |
Novel compositions and methods for cancer
|
|
WO2002082904A2
(en)
*
|
2001-04-13 |
2002-10-24 |
The Trustees Of The University Of Pennsylvania |
Method of treating or retarding the development of blindness
|
|
JP2003088388A
(ja)
|
2001-09-14 |
2003-03-25 |
Herikkusu Kenkyusho:Kk |
新規な全長cDNA
|
|
WO2005071092A1
(ja)
|
2004-01-22 |
2005-08-04 |
Dnavec Research Inc. |
サイトメガロウイルスエンハンサーおよびニワトリβ-アクチンプロモーターを含むハイブリッドプロモーターを利用したマイナス鎖RNAウイルスベクターの製造方法
|
|
US20070161031A1
(en)
|
2005-12-16 |
2007-07-12 |
The Board Of Trustees Of The Leland Stanford Junior University |
Functional arrays for high throughput characterization of gene expression regulatory elements
|
|
WO2007127428A2
(en)
|
2006-04-28 |
2007-11-08 |
University Of Florida Research Foundation, Inc. |
Double-stranded/self-complementary vectors with a truncated cba promoter and methods of gene delivery
|
|
JP5244103B2
(ja)
|
2006-08-09 |
2013-07-24 |
ホームステッド クリニカル コーポレイション |
器官特異的蛋白質およびその使用方法
|
|
US7892824B2
(en)
|
2007-01-18 |
2011-02-22 |
University Of Missouri-Columbia |
Synthetic mini/micro-dystrophin genes to restore nNOS to the sarcolemma
|
|
FR2919305B1
(fr)
|
2007-07-26 |
2009-09-18 |
Genethon Ass Loi De 1901 |
Vecteurs viraux adeno-associes pour l'expression de la dysferline.
|
|
CN101990433B
(zh)
|
2008-02-07 |
2014-11-05 |
马萨诸塞眼科耳科诊所 |
提高Atoh1表达的化合物
|
|
US20090215879A1
(en)
*
|
2008-02-26 |
2009-08-27 |
University Of North Carolina At Chapel Hill |
Methods and compositions for adeno-associated virus (aav) with hi loop mutations
|
|
US8236557B2
(en)
|
2008-05-28 |
2012-08-07 |
University Of Missouri-Columbia |
Hybrid-AAV vectors to deliver large gene expression cassette
|
|
WO2010062905A2
(en)
|
2008-11-26 |
2010-06-03 |
The Regents Of The University Of California |
Lateral ventricle cell compositions and use for treating neural degenerative diseases
|
|
KR20200047642A
(ko)
|
2010-04-23 |
2020-05-07 |
유니버시티 오브 플로리다 리서치 파운데이션, 인크. |
레베르 선천성 흑내장-1(lca1)의 치료를 위한 재조합 아데노-관련된 바이러스-구아닐레이트 사이클라제 조성물 및 방법
|
|
WO2013075008A1
(en)
|
2011-11-16 |
2013-05-23 |
University Of Florida Research Foundation Inc. |
Aav dual vector systems for gene therapy
|
|
KR102057540B1
(ko)
*
|
2012-02-17 |
2019-12-19 |
더 칠드런스 호스피탈 오브 필라델피아 |
세포, 기관 및 조직으로의 유전자 전이를 위한 aav 벡터 조성물 및 방법
|
|
WO2013151663A1
(en)
|
2012-04-02 |
2013-10-10 |
modeRNA Therapeutics |
Modified polynucleotides for the production of membrane proteins
|
|
JP6342886B2
(ja)
|
2012-04-18 |
2018-06-13 |
ザ・チルドレンズ・ホスピタル・オブ・フィラデルフィアThe Children’S Hospital Of Philadelphia |
Aavカプシドバリアントを使用した高効率な遺伝子導入のための組成物及び方法
|
|
US20150209406A1
(en)
|
2012-09-07 |
2015-07-30 |
Massachusetts Eye And Ear Infirmary |
Methods and compositions for regenerating hair cells and/or supporting cells
|
|
CA2904164C
(en)
|
2013-03-11 |
2022-10-18 |
Fondazione Telethon |
Mir-204 and mir-211 and uses thereof
|
|
EP2986635B1
(en)
|
2013-04-18 |
2018-10-03 |
Fondazione Telethon |
Effective delivery of large genes by dual aav vectors
|
|
KR102298579B1
(ko)
|
2013-05-21 |
2021-09-07 |
유니버시티 오브 플로리다 리서치 파운데이션, 인코포레이티드 |
캡시드-변형된 raav3 벡터 조성물, 및 인간 간암의 유전자 요법에서의 용도
|
|
US11000597B2
(en)
|
2015-01-21 |
2021-05-11 |
University Of Florida Research Foundation, Incorporated |
Engineered receptor/ligand system for delivery of therapeutic agents
|
|
WO2016131981A1
(en)
|
2015-02-20 |
2016-08-25 |
Institut Pasteur |
Prevention and/or treatment of hearing loss or impairment
|
|
US20180327779A1
(en)
|
2015-03-03 |
2018-11-15 |
Fondazione Telethon (IT/IT) |
Multiple vector system and uses thereof
|
|
JP2018531926A
(ja)
|
2015-09-17 |
2018-11-01 |
コーダ バイオセラピューティクス, インコーポレイテッド |
神経学的障害を処置するための組成物および方法
|
|
CN116236591B
(zh)
*
|
2015-12-11 |
2026-02-27 |
马萨诸塞眼科耳科诊所 |
用于将核酸递送至耳蜗和前庭细胞的材料和方法
|
|
EP3393522B1
(en)
|
2015-12-22 |
2021-07-07 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Improved hybrid dual recombinant aav vector systems for gene therapy
|
|
WO2017216560A1
(en)
|
2016-06-15 |
2017-12-21 |
Oxford University Innovation Limited |
Dual overlapping adeno-associated viral vector system for expressing abc4a
|
|
EP3510161A4
(en)
|
2016-08-23 |
2020-04-22 |
Akouos, Inc. |
COMPOSITIONS AND METHODS FOR TREATING PERSONAL HEARING LOSS IN A PERSON
|
|
AU2018215785B2
(en)
|
2017-02-06 |
2023-08-31 |
Children's Medical Center Corporation |
Materials and methods for delivering nucleic acids to cochlear and vestibular cells
|
|
WO2018162748A1
(en)
|
2017-03-10 |
2018-09-13 |
Genethon |
Treatment of glycogen storage disease iii
|
|
JP7240675B2
(ja)
*
|
2017-05-05 |
2023-03-16 |
ユニバーシティー オブ フロリダ リサーチ ファンデーション, インク. |
オトフェルリンを発現させるための組成物および方法
|
|
DE102018103924A1
(de)
|
2018-02-21 |
2019-08-22 |
Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts, Universitätsmedizin |
Gentherapeutische Behandlung von Schwerhörigkeit
|
|
IL276764B2
(en)
*
|
2018-02-22 |
2026-05-01 |
Akouos Inc |
Compositions and methods for treating non-age-related hearing impairment in humans
|
|
US20190345516A1
(en)
*
|
2018-03-12 |
2019-11-14 |
Musc Foundation For Research Development |
Methods for treating eye disease
|
|
AU2019237541B2
(en)
|
2018-03-23 |
2025-02-13 |
Editas Medicine, Inc. |
CRISPR/Cas9-mediated exon-skipping approach for USH2A-associated Usher syndrome
|
|
CN119410636A
(zh)
*
|
2018-04-27 |
2025-02-11 |
分贝治疗公司 |
肌球蛋白15启动子及其用途
|
|
US11660353B2
(en)
|
2018-04-27 |
2023-05-30 |
Decibel Therapeutics, Inc. |
Compositions and methods for treating sensorineural hearing loss using otoferlin dual vector systems
|
|
WO2020093018A1
(en)
*
|
2018-11-01 |
2020-05-07 |
University Of Florida Research Foundation, Incorporated |
A codon optimized otoferlin aav dual vector gene therapy
|
|
EP4063510A1
(en)
|
2018-11-07 |
2022-09-28 |
Akouos, Inc. |
Use of adeno-associated viral vectors to correct gene defects/ express proteins in hair cells and supporting cells in the inner ear
|
|
MX2021008542A
(es)
|
2019-01-18 |
2021-11-12 |
Voyager Therapeutics Inc |
Métodos y sistemas para la producción de partículas de aav.
|
|
BR112021013996A2
(pt)
|
2019-01-18 |
2021-10-26 |
Institut Pasteur |
Terapia gênica mediada por aav que recupera o gene otoferlina
|
|
JP7562544B2
(ja)
*
|
2019-02-08 |
2024-10-07 |
デシベル セラピューティクス インコーポレイテッド |
ミオシン15プロモーター及びその使用
|
|
EP3921032A4
(en)
|
2019-02-08 |
2022-11-30 |
Decibel Therapeutics, Inc. |
COMPOSITIONS AND METHODS FOR TREATMENT OF SENSORINEURAL HEARING LOSS USING OTOFERLIN DOUBLE VECTOR SYSTEMS
|
|
JP7665609B2
(ja)
|
2019-10-30 |
2025-04-21 |
デシベル セラピューティクス インコーポレイテッド |
オトフェリン二重ベクター系及びそれを含む感音難聴を治療するための組成物
|
|
CN116096905A
(zh)
|
2020-02-21 |
2023-05-09 |
阿库斯股份有限公司 |
用于治疗人受试者的非年龄相关性听力损伤的组合物和方法
|
|
CA3174500A1
(en)
|
2020-04-01 |
2021-10-07 |
University Of Florida Research Foundation, Incorporated |
Dual aav-myo7a vectors with improved safety for the treatment of ush1b
|
|
WO2022178298A1
(en)
|
2021-02-19 |
2022-08-25 |
Decibel Therapeutics, Inc. |
Methods for treating sensorineural hearing loss using otoferlin dual vector systems
|
|
IL322655A
(en)
|
2023-02-17 |
2025-10-01 |
Decibel Therapeutics Inc |
Method and compositions for administering a dual autopralin vector system
|