JP2022554280A - メンストルアローム解析のための方法およびシステム - Google Patents

メンストルアローム解析のための方法およびシステム Download PDF

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JP2022554280A
JP2022554280A JP2022525299A JP2022525299A JP2022554280A JP 2022554280 A JP2022554280 A JP 2022554280A JP 2022525299 A JP2022525299 A JP 2022525299A JP 2022525299 A JP2022525299 A JP 2022525299A JP 2022554280 A JP2022554280 A JP 2022554280A
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sample
mir
menstrual
biomarkers
menstrualome
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JP2022554280A5 (https=
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スティーブン ガイア，
リディ タリヤル，
トレバー ルッジェロ，
エイドリアン クラーク，
コービン マン，
ジェイコブ フリーク，
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ネクストジェン ジェイン， インコーポレイテッド
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
    • A61B10/0045—Devices for taking samples of body liquids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14507—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue specially adapted for measuring characteristics of body fluids other than blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14546—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring analytes not otherwise provided for, e.g. ions, cytochromes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150755—Blood sample preparation for further analysis, e.g. by separating blood components or by mixing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/43—Detecting, measuring or recording for evaluating the reproductive systems
    • A61B5/4306—Detecting, measuring or recording for evaluating the reproductive systems for evaluating the female reproductive systems, e.g. gynaecological evaluations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7235—Details of waveform analysis
    • A61B5/7264—Classification of physiological signals or data, e.g. using neural networks, statistical classifiers, expert systems or fuzzy systems
    • A61B5/7267—Classification of physiological signals or data, e.g. using neural networks, statistical classifiers, expert systems or fuzzy systems involving training the classification device
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G01N33/76—Human chorionic gonadotropin including luteinising hormone, follicle stimulating hormone, thyroid stimulating hormone or their receptors
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
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    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/30—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indices; for individual health risk assessment
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
    • A61B10/0045—Devices for taking samples of body liquids
    • A61B2010/0074—Vaginal or cervical secretions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150015—Source of blood
    • A61B5/150045—Source of blood for blood from vagina, placenta, colon or mouth
    • A—HUMAN NECESSITIES
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    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150343—Collection vessels for collecting blood samples from the skin surface, e.g. test tubes, cuvettes
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification
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    • C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA
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    • G01N2800/36—Gynecology or obstetrics
    • G01N2800/361—Menstrual abnormalities or abnormal uterine bleeding, e.g. dysmenorrhea

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  • Heart & Thoracic Surgery (AREA)
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  • Proteomics, Peptides & Aminoacids (AREA)
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  • Immunology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
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JP2022525299A 2019-11-01 2020-10-30 メンストルアローム解析のための方法およびシステム Pending JP2022554280A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201962929579P 2019-11-01 2019-11-01
US62/929,579 2019-11-01
US201962930465P 2019-11-04 2019-11-04
US62/930,465 2019-11-04
US202063061709P 2020-08-05 2020-08-05
US63/061,709 2020-08-05
PCT/US2020/058406 WO2021087395A1 (en) 2019-11-01 2020-10-30 Methods and systems for menstrualome analysis

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JP2022554280A true JP2022554280A (ja) 2022-12-28
JP2022554280A5 JP2022554280A5 (https=) 2023-11-02

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JP2022525299A Pending JP2022554280A (ja) 2019-11-01 2020-10-30 メンストルアローム解析のための方法およびシステム
JP2022525301A Active JP7809636B2 (ja) 2019-11-01 2020-10-30 流体の特徴付けのための方法

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EP (2) EP4051127A4 (https=)
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CN (2) CN115768351A (https=)
AU (2) AU2020373103A1 (https=)
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KR102710432B1 (ko) 2015-08-20 2024-09-25 왓킨스-콘티 프로덕츠 인크. 가요성 원추형 질내 지지 장치
CN111918621B (zh) 2018-03-16 2024-05-14 沃特金斯-孔蒂产品股份有限公司 阴道内支撑装置和方法
WO2024048514A1 (ja) * 2022-08-29 2024-03-07 学校法人藤田学園 子宮頸がんおよび／または子宮頸部上皮内腫瘍の検査方法
IL296623A (en) * 2022-09-19 2024-04-01 Fertilai Ltd Method and computer program product for prediction of a patient’s precise date of ovulation
WO2025076224A1 (en) * 2023-10-03 2025-04-10 Dana-Farber Cancer Institute, Inc. Ovarian cancer diagnostics
WO2025255476A1 (en) * 2024-06-06 2025-12-11 The Regents Of The University Of California A process for identifying health outcomes through epigenetic prediction
GB202414409D0 (en) * 2024-10-01 2024-11-13 Genie Fertility Ltd Diagnosis
CN119784748B (zh) * 2025-03-09 2025-05-02 中国民用航空飞行学院 一种基于影像的图像处理分析系统及方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016094409A1 (en) * 2014-12-09 2016-06-16 Villarreal Anna Methods and devices for female health monitoring
US20190125316A1 (en) * 2016-04-13 2019-05-02 Nextgen Jane, Inc. Sample collection and preservation devices, systems and methods

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6063042A (en) * 1998-09-28 2000-05-16 Navot; Nir Method for diagnosis of menorrhagia menstrual cycle disorders and their causes
AU6486299A (en) * 1998-10-30 2000-05-22 Ronnie Bottom Device method and system for diagnosis of menorrhagia menstrual cycle disorders and their causes
JP2003207509A (ja) * 2001-12-18 2003-07-25 F Hoffmann La Roche Ag 月経血からの子宮内膜症の診断
EP1321768A1 (en) * 2001-12-18 2003-06-25 Roche Diagnostics GmbH Diagnosis of endometriosis from menstrual blood
WO2005059557A1 (en) * 2003-12-16 2005-06-30 Monash University Methods of predicting, diagnosing and monitoring term and pre-term labour
CN1929506A (zh) * 2006-09-22 2007-03-14 华为技术有限公司 基于手机推算妇女生理周期的方法及其手机
KR101043261B1 (ko) * 2009-01-23 2011-06-21 서강대학교산학협력단 개인 맞춤형 월경기 또는 가임기 예측 시스템 및 그 계산방법
GB201403489D0 (en) * 2014-02-27 2014-04-16 Univ London Queen Mary Biomarkers for endometriosis
GB2543728B (en) * 2014-08-12 2019-04-17 Nextgen Jane Inc Medical kit and method for processing a biological sample
US10993645B2 (en) * 2014-08-21 2021-05-04 Qurasense Inc. System and method for non-invasive analysis of bodily fluids
US20160106398A1 (en) 2014-10-15 2016-04-21 Narmadha Kuppuswami System and Method to Identify Abnormal Menstrual Cycles and Alert the User
US10973496B2 (en) * 2016-03-18 2021-04-13 Qurasense, Inc. Collection device for diagnostics of vaginal discharge
EP3435261A1 (de) * 2017-07-28 2019-01-30 Bayer AG Vorhersage des blutungsverhaltens von frauen nach einsetzen eines intrauterinen wirkstofffreisetzungssystems
WO2019046494A1 (en) * 2017-08-30 2019-03-07 Dot Laboratories, Inc. METHODS AND COMPOSITIONS FOR DETECTION AND TREATMENT OF ENDOMETRIOSIS
DE102019113723A1 (de) * 2019-05-23 2020-11-26 Stefan Kissler In-vitro-Testverfahren zur Früherkennung von Endometriose und/oder uteriner Adenomyose

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016094409A1 (en) * 2014-12-09 2016-06-16 Villarreal Anna Methods and devices for female health monitoring
US20190125316A1 (en) * 2016-04-13 2019-05-02 Nextgen Jane, Inc. Sample collection and preservation devices, systems and methods

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
FORENSIC SCIENCE INTERNATIONAL: GENETICS, vol. 34, JPN7025002822, 2018, pages 206 - 221, ISSN: 0005628877 *

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CN115768351A (zh) 2023-03-07
WO2021087374A1 (en) 2021-05-06
JP2022554281A (ja) 2022-12-28
JP7809636B2 (ja) 2026-02-02
CA3156531A1 (en) 2021-05-06
US20220396836A1 (en) 2022-12-15
AU2020376052A1 (en) 2022-06-02
AU2020373103A1 (en) 2022-06-02
EP4051109A4 (en) 2023-11-29
EP4051127A1 (en) 2022-09-07
US20230017064A1 (en) 2023-01-19
WO2021087395A1 (en) 2021-05-06
CN115066207A (zh) 2022-09-16
CA3156520A1 (en) 2021-05-06
EP4051109A1 (en) 2022-09-07
EP4051127A4 (en) 2024-02-28

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