JP2022552839A5 - - Google Patents

Info

Publication number
JP2022552839A5
JP2022552839A5 JP2022522669A JP2022522669A JP2022552839A5 JP 2022552839 A5 JP2022552839 A5 JP 2022552839A5 JP 2022522669 A JP2022522669 A JP 2022522669A JP 2022522669 A JP2022522669 A JP 2022522669A JP 2022552839 A5 JP2022552839 A5 JP 2022552839A5
Authority
JP
Japan
Prior art keywords
drug conjugate
conjugate according
peptide
specific
peptide ligands
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022522669A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022552839A (ja
Filing date
Publication date
Priority claimed from GB201914872A external-priority patent/GB201914872D0/en
Application filed filed Critical
Publication of JP2022552839A publication Critical patent/JP2022552839A/ja
Publication of JP2022552839A5 publication Critical patent/JP2022552839A5/ja
Pending legal-status Critical Current

Links

JP2022522669A 2019-10-15 2020-10-15 二環式ペプチドリガンド薬物コンジュゲート Pending JP2022552839A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1914872.5 2019-10-15
GB201914872A GB201914872D0 (en) 2019-10-15 2019-10-15 Bicyclic peptide ligand drug conjugates
PCT/GB2020/052590 WO2021074622A1 (en) 2019-10-15 2020-10-15 Bicyclic peptide ligand drug conjugates

Publications (2)

Publication Number Publication Date
JP2022552839A JP2022552839A (ja) 2022-12-20
JP2022552839A5 true JP2022552839A5 (enExample) 2023-10-19

Family

ID=68619460

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022522669A Pending JP2022552839A (ja) 2019-10-15 2020-10-15 二環式ペプチドリガンド薬物コンジュゲート

Country Status (12)

Country Link
US (1) US20240173422A1 (enExample)
EP (1) EP4045089A1 (enExample)
JP (1) JP2022552839A (enExample)
KR (1) KR20220088416A (enExample)
CN (1) CN114901317A (enExample)
AU (1) AU2020367325A1 (enExample)
BR (1) BR112022007099A2 (enExample)
CA (1) CA3154672A1 (enExample)
GB (1) GB201914872D0 (enExample)
IL (1) IL292113A (enExample)
MX (1) MX2022004572A (enExample)
WO (1) WO2021074622A1 (enExample)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ731185A (en) 2014-10-29 2024-03-22 Bicyclerd Ltd Bicyclic peptide ligands specific for mt1-mmp
WO2019002842A1 (en) 2017-06-26 2019-01-03 Bicyclerd Limited BICYCLIC PEPTIDE LIGANDS WITH DETECTABLE FRACTIONS AND USES THEREOF
JP7670481B2 (ja) 2017-08-04 2025-04-30 バイスクルテクス・リミテッド Cd137に対して特異的な二環式ペプチドリガンド
CA3091775A1 (en) 2018-02-23 2019-08-29 Bicycletx Limited Multimeric bicyclic peptide ligands
US11180531B2 (en) 2018-06-22 2021-11-23 Bicycletx Limited Bicyclic peptide ligands specific for Nectin-4
GB201820295D0 (en) 2018-12-13 2019-01-30 Bicyclerd Ltd Bicyclic peptide ligands specific for MT1-MMP
GB201820288D0 (en) 2018-12-13 2019-01-30 Bicycle Tx Ltd Bicycle peptide ligaands specific for MT1-MMP
GB201820325D0 (en) 2018-12-13 2019-01-30 Bicyclerd Ltd Bicyclic peptide ligands specific for psma
WO2020128527A1 (en) 2018-12-21 2020-06-25 Bicyclerd Limited Bicyclic peptide ligands specific for pd-l1
EP3897849A1 (en) 2018-12-21 2021-10-27 BicycleTx Limited Bicyclic peptide ligands specific for pd-l1
GB201900529D0 (en) 2019-01-15 2019-03-06 Bicycletx Ltd Bicyclic peptide ligands specific for CD38
TWI860386B (zh) 2019-07-30 2024-11-01 英商拜西可泰克斯有限公司 異質雙環肽複合物
CN116348476A (zh) 2020-08-03 2023-06-27 拜斯科技术开发有限公司 基于肽的接头
GB202016331D0 (en) * 2020-10-15 2020-12-02 Bicyclerd Ltd Bicyclic peptide ligand drug conjugates
WO2022253051A1 (zh) * 2021-06-01 2022-12-08 南京明德新药研发有限公司 多肽偶联药物及其应用
US12539335B2 (en) 2021-09-29 2026-02-03 Conjustar (Zhuhai) Biologics Co., Ltd. Tricyclic polypeptide conjugated drug and use thereof
GB202114279D0 (en) * 2021-10-06 2021-11-17 Bicycletx Ltd Bicyclic peptide ligand drug conjugates
WO2023066314A1 (zh) * 2021-10-19 2023-04-27 海思科医药集团股份有限公司 Nectin-4的双环肽配体及其用途
CN116768978A (zh) * 2022-03-11 2023-09-19 上海智肽生物科技有限公司 Nectin-4靶向肽化合物及其药物偶联物
CN117003830A (zh) * 2023-08-04 2023-11-07 湖南中晟全肽生化有限公司 靶向Nectin-4的多肽及其用途
CN119701000B (zh) * 2024-12-25 2026-07-17 中国人民解放军空军军医大学 一类多肽偶联药物及其制备方法和应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1452868A2 (en) 2003-02-27 2004-09-01 Pepscan Systems B.V. Method for selecting a candidate drug compound
ES2428869T3 (es) 2005-01-24 2013-11-12 Pepscan Systems B.V. Compuestos de unión, compuestos inmunógenos y peptidomiméticos
JP6074574B2 (ja) 2008-02-05 2017-02-08 バイシクル セラピューティクス リミテッド 方法及び組成物
NZ731185A (en) 2014-10-29 2024-03-22 Bicyclerd Ltd Bicyclic peptide ligands specific for mt1-mmp
CA3091775A1 (en) * 2018-02-23 2019-08-29 Bicycletx Limited Multimeric bicyclic peptide ligands
CA3095582A1 (en) * 2018-04-04 2019-10-10 Bicycletx Limited Heterotandem bicyclic peptide complexes
US11180531B2 (en) * 2018-06-22 2021-11-23 Bicycletx Limited Bicyclic peptide ligands specific for Nectin-4

Similar Documents

Publication Publication Date Title
JP7241811B2 (ja) 四級化チューブリシン化合物の複合体
JP2022517698A5 (enExample)
JP2022512478A5 (enExample)
TWI811726B (zh) 改良配體-藥物結合物之藥物動力學之聚乙二醇化藥物連接子
JP6290187B2 (ja) 癌の処置のためのタンパク質の部位特異的標識及び標的送達
JP2022517040A5 (enExample)
JP2022518210A5 (enExample)
JP2022513223A5 (enExample)
JP2023512501A5 (enExample)
JP2020510662A5 (enExample)
JP2022514687A5 (enExample)
JP2022517442A5 (enExample)
JP2016501204A5 (enExample)
US11464867B2 (en) Multimeric elastin-like polypeptides
JP2008515889A5 (enExample)
US20100323969A1 (en) Compounds Binding to P-Selectin
JP6633523B2 (ja) Psd−95の二量体阻害剤脂肪酸誘導体
JP2019513696A (ja) 感染症を治療するステープル化細胞内ターゲティング抗微生物ペプチド
JP2016509586A5 (enExample)
KR20210052473A (ko) 면역조정 특성을 갖는 펩티드
Avan et al. Benzotriazole-mediated syntheses of depsipeptides and oligoesters
JP2024515306A5 (enExample)
US20230131339A1 (en) Epi-x4 based peptides and derivatives thereof
JP2007506713A (ja) 例えば、抗血管新生活性を有するペプチドおよび治療におけるその適用
JP2020537690A (ja) プレクチン1結合抗体およびその使用