JP2022517698A5 - - Google Patents

Info

Publication number
JP2022517698A5
JP2022517698A5 JP2021563434A JP2021563434A JP2022517698A5 JP 2022517698 A5 JP2022517698 A5 JP 2022517698A5 JP 2021563434 A JP2021563434 A JP 2021563434A JP 2021563434 A JP2021563434 A JP 2021563434A JP 2022517698 A5 JP2022517698 A5 JP 2022517698A5
Authority
JP
Japan
Prior art keywords
referred
sequence
sar
peptide ligand
ligand according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2021563434A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022517698A (ja
Filing date
Publication date
Priority claimed from GBGB1900528.9A external-priority patent/GB201900528D0/en
Application filed filed Critical
Publication of JP2022517698A publication Critical patent/JP2022517698A/ja
Publication of JP2022517698A5 publication Critical patent/JP2022517698A5/ja
Pending legal-status Critical Current

Links

JP2021563434A 2019-01-15 2020-01-15 インテグリンαvβ3に特異的な二環式ペプチドリガンド Pending JP2022517698A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1900528.9A GB201900528D0 (en) 2019-01-15 2019-01-15 Bicyclic peptide ligands specific for integrin AVB3
GB1900528.9 2019-01-15
PCT/GB2020/050072 WO2020148528A1 (en) 2019-01-15 2020-01-15 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR INTEGRIN αVβ3

Publications (2)

Publication Number Publication Date
JP2022517698A JP2022517698A (ja) 2022-03-09
JP2022517698A5 true JP2022517698A5 (enExample) 2023-01-25

Family

ID=65528176

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021563434A Pending JP2022517698A (ja) 2019-01-15 2020-01-15 インテグリンαvβ3に特異的な二環式ペプチドリガンド

Country Status (6)

Country Link
US (1) US20220119488A1 (enExample)
EP (1) EP3965892A1 (enExample)
JP (1) JP2022517698A (enExample)
CN (1) CN113613728A (enExample)
GB (1) GB201900528D0 (enExample)
WO (1) WO2020148528A1 (enExample)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107148425B (zh) 2014-10-29 2021-08-03 拜斯科阿迪有限公司 对mt1-mmp特异性的双环肽配体
EP3645549A1 (en) 2017-06-26 2020-05-06 BicycleRD Limited Bicyclic peptide ligands with detectable moieties and uses thereof
JP7670481B2 (ja) 2017-08-04 2025-04-30 バイスクルテクス・リミテッド Cd137に対して特異的な二環式ペプチドリガンド
CN111902429A (zh) 2018-02-23 2020-11-06 拜斯科技术开发有限公司 多聚体双环肽配体
IL279489B2 (en) 2018-06-22 2025-10-01 Bicycletx Ltd Bicyclic peptide ligands specific for nectin-4, a drug conjugate containing the peptide ligands and a pharmaceutical composition containing the drug conjugate
GB201820295D0 (en) 2018-12-13 2019-01-30 Bicyclerd Ltd Bicyclic peptide ligands specific for MT1-MMP
GB201820325D0 (en) 2018-12-13 2019-01-30 Bicyclerd Ltd Bicyclic peptide ligands specific for psma
GB201820288D0 (en) 2018-12-13 2019-01-30 Bicycle Tx Ltd Bicycle peptide ligaands specific for MT1-MMP
US12492224B2 (en) 2018-12-21 2025-12-09 Bicycletx Limited Bicyclic peptide ligands specific for PD-L1
WO2020128527A1 (en) 2018-12-21 2020-06-25 Bicyclerd Limited Bicyclic peptide ligands specific for pd-l1
GB201900529D0 (en) 2019-01-15 2019-03-06 Bicycletx Ltd Bicyclic peptide ligands specific for CD38
TWI860386B (zh) 2019-07-30 2024-11-01 英商拜西可泰克斯有限公司 異質雙環肽複合物
AU2021322934A1 (en) 2020-08-03 2023-03-30 Bicycletx Limited Peptide-based linkers
BR102021016135A2 (pt) * 2021-08-16 2023-02-23 Novageia Biotecnologia Ltda Antagonistas miméticos macrocíclicos com atividade biológica, seus usos e composições
CN114656525B (zh) * 2022-04-25 2024-02-02 合肥师范学院 用于癌细胞整合素的rgd环肽及其在制备肿瘤药物中的应用
WO2026002154A1 (en) * 2024-06-27 2026-01-02 Syneron Opal Cell penetrating peptide compounds and using thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1452868A2 (en) 2003-02-27 2004-09-01 Pepscan Systems B.V. Method for selecting a candidate drug compound
WO2006078161A1 (en) 2005-01-24 2006-07-27 Pepscan Systems B.V. Binding compounds, immunogenic compounds and peptidomimetics
EP2653545A1 (en) 2008-02-05 2013-10-23 Bicycle Therapeutics Limited Methods and compositions
US9073974B2 (en) * 2009-12-21 2015-07-07 The Regents Of The University Of California RGD-containing cyclic peptides
CN107148425B (zh) * 2014-10-29 2021-08-03 拜斯科阿迪有限公司 对mt1-mmp特异性的双环肽配体
EP3645549A1 (en) * 2017-06-26 2020-05-06 BicycleRD Limited Bicyclic peptide ligands with detectable moieties and uses thereof
GB201810329D0 (en) * 2018-06-22 2018-08-08 Bicycletx Ltd Peptide ligands for binding to integrin avB3
GB201900527D0 (en) * 2019-01-15 2019-03-06 Bicycletx Ltd Bicyclic peptide ligands specific for integrin avb3

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