JP2022551607A5 - - Google Patents
Info
- Publication number
- JP2022551607A5 JP2022551607A5 JP2022520570A JP2022520570A JP2022551607A5 JP 2022551607 A5 JP2022551607 A5 JP 2022551607A5 JP 2022520570 A JP2022520570 A JP 2022520570A JP 2022520570 A JP2022520570 A JP 2022520570A JP 2022551607 A5 JP2022551607 A5 JP 2022551607A5
- Authority
- JP
- Japan
- Prior art keywords
- bicyclic peptide
- peptide complex
- complex according
- heterotandem
- heterotandem bicyclic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025101880A JP7770607B2 (ja) | 2019-10-03 | 2025-06-18 | ヘテロタンデム二環式ペプチド複合体 |
| JP2025185492A JP7876049B2 (ja) | 2019-10-03 | 2025-11-04 | ヘテロタンデム二環式ペプチド複合体 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962910129P | 2019-10-03 | 2019-10-03 | |
| US62/910,129 | 2019-10-03 | ||
| PCT/GB2020/052445 WO2021064428A1 (en) | 2019-10-03 | 2020-10-05 | Heterotandem bicyclic peptide complexes |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025101880A Division JP7770607B2 (ja) | 2019-10-03 | 2025-06-18 | ヘテロタンデム二環式ペプチド複合体 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022551607A JP2022551607A (ja) | 2022-12-12 |
| JP2022551607A5 true JP2022551607A5 (enExample) | 2023-10-10 |
Family
ID=72811890
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022520570A Pending JP2022551607A (ja) | 2019-10-03 | 2020-10-05 | ヘテロタンデム二環式ペプチド複合体 |
| JP2025101880A Active JP7770607B2 (ja) | 2019-10-03 | 2025-06-18 | ヘテロタンデム二環式ペプチド複合体 |
| JP2025185492A Active JP7876049B2 (ja) | 2019-10-03 | 2025-11-04 | ヘテロタンデム二環式ペプチド複合体 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025101880A Active JP7770607B2 (ja) | 2019-10-03 | 2025-06-18 | ヘテロタンデム二環式ペプチド複合体 |
| JP2025185492A Active JP7876049B2 (ja) | 2019-10-03 | 2025-11-04 | ヘテロタンデム二環式ペプチド複合体 |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US11332500B2 (enExample) |
| EP (3) | EP4038096A1 (enExample) |
| JP (3) | JP2022551607A (enExample) |
| CN (2) | CN119192401A (enExample) |
| DK (1) | DK4464721T3 (enExample) |
| ES (1) | ES3033517T3 (enExample) |
| FI (1) | FI4464721T3 (enExample) |
| HR (1) | HRP20250841T1 (enExample) |
| HU (1) | HUE072242T2 (enExample) |
| LT (1) | LT4464721T (enExample) |
| PL (1) | PL4464721T3 (enExample) |
| PT (1) | PT4464721T (enExample) |
| RS (1) | RS67014B1 (enExample) |
| SI (1) | SI4464721T1 (enExample) |
| SM (1) | SMT202500247T1 (enExample) |
| WO (1) | WO2021064428A1 (enExample) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ731185A (en) | 2014-10-29 | 2024-03-22 | Bicyclerd Ltd | Bicyclic peptide ligands specific for mt1-mmp |
| WO2019002842A1 (en) | 2017-06-26 | 2019-01-03 | Bicyclerd Limited | BICYCLIC PEPTIDE LIGANDS WITH DETECTABLE FRACTIONS AND USES THEREOF |
| JP7670481B2 (ja) | 2017-08-04 | 2025-04-30 | バイスクルテクス・リミテッド | Ｃｄ１３７に対して特異的な二環式ペプチドリガンド |
| TWI825046B (zh) | 2017-12-19 | 2023-12-11 | 英商拜西可泰克斯有限公司 | Epha2特用之雙環胜肽配位基 |
| GB201721265D0 (en) | 2017-12-19 | 2018-01-31 | Bicyclerd Ltd | Bicyclic peptide ligands specific for EphA2 |
| CA3091775A1 (en) | 2018-02-23 | 2019-08-29 | Bicycletx Limited | Multimeric bicyclic peptide ligands |
| CA3095582A1 (en) | 2018-04-04 | 2019-10-10 | Bicycletx Limited | Heterotandem bicyclic peptide complexes |
| GB201810316D0 (en) | 2018-06-22 | 2018-08-08 | Bicyclerd Ltd | Peptide ligands for binding to EphA2 |
| US11180531B2 (en) | 2018-06-22 | 2021-11-23 | Bicycletx Limited | Bicyclic peptide ligands specific for Nectin-4 |
| GB201820288D0 (en) | 2018-12-13 | 2019-01-30 | Bicycle Tx Ltd | Bicycle peptide ligaands specific for MT1-MMP |
| GB201820325D0 (en) | 2018-12-13 | 2019-01-30 | Bicyclerd Ltd | Bicyclic peptide ligands specific for psma |
| GB201820295D0 (en) | 2018-12-13 | 2019-01-30 | Bicyclerd Ltd | Bicyclic peptide ligands specific for MT1-MMP |
| EP3897849A1 (en) | 2018-12-21 | 2021-10-27 | BicycleTx Limited | Bicyclic peptide ligands specific for pd-l1 |
| WO2020128527A1 (en) | 2018-12-21 | 2020-06-25 | Bicyclerd Limited | Bicyclic peptide ligands specific for pd-l1 |
| GB201900529D0 (en) | 2019-01-15 | 2019-03-06 | Bicycletx Ltd | Bicyclic peptide ligands specific for CD38 |
| KR20220007098A (ko) | 2019-05-09 | 2022-01-18 | 바이사이클티엑스 리미티드 | Ox40에 특이적인 이환식 펩티드 리간드 |
| TWI860386B (zh) | 2019-07-30 | 2024-11-01 | 英商拜西可泰克斯有限公司 | 異質雙環肽複合物 |
| SI4464721T1 (sl) | 2019-10-03 | 2025-08-29 | Bicycletx Limited | Heterotandemski biciklični peptidni kompleksi |
| KR20220146543A (ko) | 2020-02-27 | 2022-11-01 | 본스인코오포레이티드 | 수정된 에지를 갖는 mov 관련 디바이스 및 방법 |
| WO2021222593A2 (en) | 2020-04-29 | 2021-11-04 | University Of Southern California | Pd-l1 binding peptides |
| CN116348476A (zh) | 2020-08-03 | 2023-06-27 | 拜斯科技术开发有限公司 | 基于肽的接头 |
| US20250186539A2 (en) * | 2021-01-11 | 2025-06-12 | Bicycletx Limited | Methods for treating cancer |
| WO2022253051A1 (zh) * | 2021-06-01 | 2022-12-08 | 南京明德新药研发有限公司 | 多肽偶联药物及其应用 |
| EP4704904A1 (en) * | 2023-05-04 | 2026-03-11 | Tambo, Inc. | Tetrazine-based targeting agents for in vivo delivery of a payload |
| JP2026525826A (ja) * | 2023-06-23 | 2026-08-04 | バイスクルテクス・リミテッド | Ｎｋ細胞に特異的な二環式ペプチドリガンド |
| DE112023006927T5 (de) | 2023-09-19 | 2026-07-09 | Kao Corporation | Struktur zur herstellung eines gusserzeugnisses |
| WO2025191096A1 (en) * | 2024-03-14 | 2025-09-18 | Bicycletx Limited | Bicyclic peptide |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4658014A (en) | 1985-12-20 | 1987-04-14 | Kempe Tomas G | Synthetic peptides with calcitonin-like activity |
| EP1452868A2 (en) | 2003-02-27 | 2004-09-01 | Pepscan Systems B.V. | Method for selecting a candidate drug compound |
| ES2428869T3 (es) | 2005-01-24 | 2013-11-12 | Pepscan Systems B.V. | Compuestos de unión, compuestos inmunógenos y peptidomiméticos |
| WO2007092447A2 (en) * | 2006-02-06 | 2007-08-16 | Burnham Institute For Medical Research | Methods and compositions related to targeting tumors and wounds |
| JP6074574B2 (ja) | 2008-02-05 | 2017-02-08 | バイシクル セラピューティクス リミテッド | 方法及び組成物 |
| GB0913775D0 (en) | 2009-08-06 | 2009-09-16 | Medical Res Council | Multispecific peptides |
| WO2011120071A1 (en) | 2010-04-01 | 2011-10-06 | The University Of Queensland | Oxytocin peptide analogues |
| WO2012057624A1 (en) | 2010-10-25 | 2012-05-03 | Pepscan Systems B.V. | Novel bicyclic peptide mimetics |
| JP6254527B2 (ja) | 2011-10-07 | 2017-12-27 | バイサイクル・セラピューティクス・リミテッド | 構造化ポリペプチドの特異性のモジュレーション |
| GB201306623D0 (en) | 2013-04-11 | 2013-05-29 | Bicycle Therapeutics Ltd | Modulation of structured polypeptide specificity |
| CA2949936C (en) * | 2014-06-10 | 2022-10-18 | 3B Pharmaceuticals Gmbh | Conjugate comprising a neurotensin receptor ligand and use thereof |
| NZ731185A (en) | 2014-10-29 | 2024-03-22 | Bicyclerd Ltd | Bicyclic peptide ligands specific for mt1-mmp |
| WO2017069269A1 (ja) * | 2015-10-23 | 2017-04-27 | 富士フイルム株式会社 | 環状ペプチド、アフィニティクロマトグラフィー担体、標識化抗体、抗体薬物複合体、および医薬製剤 |
| KR102775461B1 (ko) | 2016-04-01 | 2025-02-28 | 어비디티 바이오사이언시스 인크. | 핵산-폴리펩타이드 조성물 및 이의 용도 |
| BR112018071612A2 (pt) | 2016-04-22 | 2019-02-19 | Alligator Bioscience Ab | polipeptídeos biespecíficos inovadores contra cd137 |
| GB201607827D0 (en) * | 2016-05-04 | 2016-06-15 | Bicycle Therapeutics Ltd | Bicyclic peptide-toxin conjugates specific for MT1-MMP |
| BR112019017628A2 (pt) | 2017-02-24 | 2020-07-07 | Macrogenics, Inc. | molécula de ligação a cd137 x ta, composições farmacêuticas, uso da molécula de ligação a cd137 x ta, molécula de ligação a cd137, uso da molécula de ligação a cd137, molécula de ligação a her2/neu, uso da molécula de ligação a her2/neu, e uso de uma composição |
| JP7670481B2 (ja) | 2017-08-04 | 2025-04-30 | バイスクルテクス・リミテッド | Ｃｄ１３７に対して特異的な二環式ペプチドリガンド |
| GB201721265D0 (en) | 2017-12-19 | 2018-01-31 | Bicyclerd Ltd | Bicyclic peptide ligands specific for EphA2 |
| TWI825046B (zh) | 2017-12-19 | 2023-12-11 | 英商拜西可泰克斯有限公司 | Epha2特用之雙環胜肽配位基 |
| CA3091775A1 (en) | 2018-02-23 | 2019-08-29 | Bicycletx Limited | Multimeric bicyclic peptide ligands |
| CA3095582A1 (en) * | 2018-04-04 | 2019-10-10 | Bicycletx Limited | Heterotandem bicyclic peptide complexes |
| US11180531B2 (en) | 2018-06-22 | 2021-11-23 | Bicycletx Limited | Bicyclic peptide ligands specific for Nectin-4 |
| GB201810316D0 (en) | 2018-06-22 | 2018-08-08 | Bicyclerd Ltd | Peptide ligands for binding to EphA2 |
| WO2020084305A1 (en) | 2018-10-23 | 2020-04-30 | Bicycletx Limited | Bicyclic peptide ligands and uses thereof |
| EP3897849A1 (en) | 2018-12-21 | 2021-10-27 | BicycleTx Limited | Bicyclic peptide ligands specific for pd-l1 |
| US20220184222A1 (en) | 2019-04-02 | 2022-06-16 | Bicycletx Limited | Bicycle toxin conjugates and uses thereof |
| KR20220007098A (ko) * | 2019-05-09 | 2022-01-18 | 바이사이클티엑스 리미티드 | Ox40에 특이적인 이환식 펩티드 리간드 |
| TWI860386B (zh) | 2019-07-30 | 2024-11-01 | 英商拜西可泰克斯有限公司 | 異質雙環肽複合物 |
| US20220275053A1 (en) * | 2019-08-13 | 2022-09-01 | Bicycletx Limited | Modified multimeric bicyclic peptide ligands |
| SI4464721T1 (sl) | 2019-10-03 | 2025-08-29 | Bicycletx Limited | Heterotandemski biciklični peptidni kompleksi |
-
2020
- 2020-10-05 SI SI202030628T patent/SI4464721T1/sl unknown
- 2020-10-05 US US17/062,662 patent/US11332500B2/en not_active Expired - Fee Related
- 2020-10-05 RS RS20250710A patent/RS67014B1/sr unknown
- 2020-10-05 ES ES24203287T patent/ES3033517T3/es active Active
- 2020-10-05 CN CN202411379106.7A patent/CN119192401A/zh active Pending
- 2020-10-05 LT LTEP24203287.8T patent/LT4464721T/lt unknown
- 2020-10-05 DK DK24203287.8T patent/DK4464721T3/da active
- 2020-10-05 PL PL24203287.8T patent/PL4464721T3/pl unknown
- 2020-10-05 EP EP20789240.7A patent/EP4038096A1/en not_active Withdrawn
- 2020-10-05 CN CN202080069454.8A patent/CN114867753A/zh active Pending
- 2020-10-05 JP JP2022520570A patent/JP2022551607A/ja active Pending
- 2020-10-05 HU HUE24203287A patent/HUE072242T2/hu unknown
- 2020-10-05 FI FIEP24203287.8T patent/FI4464721T3/fi active
- 2020-10-05 PT PT242032878T patent/PT4464721T/pt unknown
- 2020-10-05 HR HRP20250841TT patent/HRP20250841T1/hr unknown
- 2020-10-05 EP EP24203287.8A patent/EP4464721B1/en active Active
- 2020-10-05 WO PCT/GB2020/052445 patent/WO2021064428A1/en not_active Ceased
- 2020-10-05 SM SM20250247T patent/SMT202500247T1/it unknown
- 2020-10-05 EP EP25175050.1A patent/EP4592309A3/en active Pending
-
2022
- 2022-03-22 US US17/655,822 patent/US20220306694A1/en not_active Abandoned
-
2025
- 2025-06-18 JP JP2025101880A patent/JP7770607B2/ja active Active
- 2025-11-04 JP JP2025185492A patent/JP7876049B2/ja active Active
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