JP2022548796A5 - - Google Patents

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Publication number
JP2022548796A5
JP2022548796A5 JP2022518818A JP2022518818A JP2022548796A5 JP 2022548796 A5 JP2022548796 A5 JP 2022548796A5 JP 2022518818 A JP2022518818 A JP 2022518818A JP 2022518818 A JP2022518818 A JP 2022518818A JP 2022548796 A5 JP2022548796 A5 JP 2022548796A5
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JP
Japan
Prior art keywords
chimeric polypeptide
cell
polypeptide according
sequence
domain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022518818A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022548796A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2020/052327 external-priority patent/WO2021061862A1/en
Publication of JP2022548796A publication Critical patent/JP2022548796A/ja
Publication of JP2022548796A5 publication Critical patent/JP2022548796A5/ja
Priority to JP2025171960A priority Critical patent/JP2026047360A/ja
Pending legal-status Critical Current

Links

JP2022518818A 2019-09-24 2020-09-23 ヒンジドメインを有するノッチ受容体 Pending JP2022548796A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025171960A JP2026047360A (ja) 2019-09-24 2025-10-10 ヒンジドメインを有するノッチ受容体

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962905251P 2019-09-24 2019-09-24
US201962905263P 2019-09-24 2019-09-24
US62/905,251 2019-09-24
US62/905,263 2019-09-24
PCT/US2020/052327 WO2021061862A1 (en) 2019-09-24 2020-09-23 Notch receptors with hinge domain

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025171960A Division JP2026047360A (ja) 2019-09-24 2025-10-10 ヒンジドメインを有するノッチ受容体

Publications (2)

Publication Number Publication Date
JP2022548796A JP2022548796A (ja) 2022-11-21
JP2022548796A5 true JP2022548796A5 (https=) 2023-10-03

Family

ID=75167117

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2022518818A Pending JP2022548796A (ja) 2019-09-24 2020-09-23 ヒンジドメインを有するノッチ受容体
JP2025171960A Pending JP2026047360A (ja) 2019-09-24 2025-10-10 ヒンジドメインを有するノッチ受容体

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2025171960A Pending JP2026047360A (ja) 2019-09-24 2025-10-10 ヒンジドメインを有するノッチ受容体

Country Status (21)

Country Link
US (3) US11202801B2 (https=)
EP (2) EP4034252B1 (https=)
JP (2) JP2022548796A (https=)
KR (1) KR20220087454A (https=)
CN (2) CN114761084B (https=)
AU (1) AU2020355031A1 (https=)
BR (1) BR112022005283A2 (https=)
CA (1) CA3155661A1 (https=)
DK (1) DK4034252T3 (https=)
ES (1) ES3008682T3 (https=)
FI (1) FI4034252T3 (https=)
HR (1) HRP20250135T1 (https=)
HU (1) HUE069963T2 (https=)
IL (2) IL307609B2 (https=)
LT (1) LT4034252T (https=)
PL (1) PL4034252T3 (https=)
PT (1) PT4034252T (https=)
RS (1) RS66476B1 (https=)
SI (1) SI4034252T1 (https=)
SM (1) SMT202500031T1 (https=)
WO (1) WO2021061862A1 (https=)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2020355031A1 (en) 2019-09-24 2022-05-19 The Regents Of The University Of California Notch receptors with hinge domain
CN115666726A (zh) * 2020-04-09 2023-01-31 加利福尼亚大学董事会 具有铰链结构域的人源化Notch受体
CN117255799A (zh) * 2021-03-23 2023-12-19 加利福尼亚大学董事会 用于定制抗原诱导的转录调控的合成膜间蛋白水解受体
JP2024537991A (ja) 2021-10-14 2024-10-18 アーセナル バイオサイエンシズ インコーポレイテッド 共発現されるshRNAと論理ゲートシステムとを有する免疫細胞
EP4444748A4 (en) * 2021-12-07 2025-12-24 Univ California SYNTHETIC CYTOKINE CIRCUITS TO PROMOTE INFILTRATION AND ELIMINATION OF SOLID TUMORS EXCLUDED FROM THE IMMUNE SYSTEM BY MODIFIED IMMUNE CELLS
CN114349840B (zh) * 2021-12-13 2024-07-12 中山大学肿瘤防治中心(中山大学附属肿瘤医院、中山大学肿瘤研究所) 一种融合蛋白及其制备方法与应用
CN114621929B (zh) * 2021-12-21 2023-05-30 河南省肿瘤医院 一种抗肿瘤树突状细胞及其制备方法、表达载体及应用
AU2023273025A1 (en) * 2022-05-16 2024-11-28 The Regents Of The University Of California T cell activation responsive constructs for enhanced car-t cell therapy
IL322949A (en) 2023-03-03 2025-10-01 Arsenal Biosciences Inc Systems targeting PSMA and CA9
WO2024249416A2 (en) * 2023-06-01 2024-12-05 Vanderbilt University Engineered cells to detect and respond to amyloid beta peptides
CN117304343B (zh) * 2023-10-11 2024-05-07 北京景达生物科技有限公司 Gpc3靶向的car-nk细胞的制备及其应用
CN120248130A (zh) * 2023-12-28 2025-07-04 上海恩凯细胞技术有限公司 特异性靶向肿瘤的转基因重组免疫细胞及其应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX9700800A (es) * 1994-08-02 1997-11-29 Gen Hospital Corp Células portadoras de receptores de señuelo cd4 y moléculas y métodos relacionados.
NZ759969A (en) * 2013-12-20 2022-12-23 Fred Hutchinson Cancer Center Tagged chimeric effector molecules and receptors thereof
KR102624023B1 (ko) * 2015-02-24 2024-01-11 더 리젠츠 오브 더 유니버시티 오브 캘리포니아 결합-촉발된 전사 스위치 및 이들의 이용 방법
IL260532B2 (en) * 2016-01-11 2023-12-01 Univ Leland Stanford Junior Chimeric proteins- containing systems and uses thereof in regulating gene expression
CN109843929B (zh) * 2016-08-23 2024-07-05 加利福尼亚大学董事会 蛋白水解可切割的嵌合多肽及其使用方法
EP3568466A4 (en) * 2017-01-10 2020-07-15 The General Hospital Corporation TARGETED T CELLS WITH CYTOTOXICITY TO IMMUNOSUPPRESSIVE CELLS
US11325957B2 (en) * 2017-06-19 2022-05-10 Cell Design Labs, Inc. Methods and compositions for reducing the immunogenicity of chimeric notch receptors
US10724680B2 (en) * 2017-07-06 2020-07-28 Robert Anthony Benson, SR. Personal device holder
US11771718B2 (en) * 2017-10-18 2023-10-03 Precigen, Inc. Polypeptide compositions comprising spacers
AU2020355031A1 (en) 2019-09-24 2022-05-19 The Regents Of The University Of California Notch receptors with hinge domain

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