JP2021512635A5 - - Google Patents

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Publication number
JP2021512635A5
JP2021512635A5 JP2020542979A JP2020542979A JP2021512635A5 JP 2021512635 A5 JP2021512635 A5 JP 2021512635A5 JP 2020542979 A JP2020542979 A JP 2020542979A JP 2020542979 A JP2020542979 A JP 2020542979A JP 2021512635 A5 JP2021512635 A5 JP 2021512635A5
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JP
Japan
Prior art keywords
car
seq
antigen
cell
domain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2020542979A
Other languages
English (en)
Japanese (ja)
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JP2021512635A (ja
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Publication date
Priority claimed from PCT/US2018/027783 external-priority patent/WO2018191748A1/en
Application filed filed Critical
Priority claimed from PCT/US2019/017727 external-priority patent/WO2019157533A1/en
Publication of JP2021512635A publication Critical patent/JP2021512635A/ja
Publication of JP2021512635A5 publication Critical patent/JP2021512635A5/ja
Priority to JP2024193719A priority Critical patent/JP2025032089A/ja
Pending legal-status Critical Current

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JP2020542979A 2018-02-12 2019-02-12 腫瘍微小環境を標的とするキメラ抗原受容体 Pending JP2021512635A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024193719A JP2025032089A (ja) 2018-02-12 2024-11-05 腫瘍微小環境を標的とするキメラ抗原受容体

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201862629593P 2018-02-12 2018-02-12
US62/629,593 2018-02-12
US201862658307P 2018-04-16 2018-04-16
USPCT/US2018/027783 2018-04-16
US62/658,307 2018-04-16
PCT/US2018/027783 WO2018191748A1 (en) 2017-04-14 2018-04-16 Chimeric antigen receptor t cells targeting the tumor microenvironment
US201862746895P 2018-10-17 2018-10-17
US62/746,895 2018-10-17
PCT/US2019/017727 WO2019157533A1 (en) 2018-02-12 2019-02-12 Chimeric antigen receptors targeting the tumor microenvironment

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2024193719A Division JP2025032089A (ja) 2018-02-12 2024-11-05 腫瘍微小環境を標的とするキメラ抗原受容体

Publications (2)

Publication Number Publication Date
JP2021512635A JP2021512635A (ja) 2021-05-20
JP2021512635A5 true JP2021512635A5 (https=) 2022-02-22

Family

ID=67548600

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2020542979A Pending JP2021512635A (ja) 2018-02-12 2019-02-12 腫瘍微小環境を標的とするキメラ抗原受容体
JP2024193719A Pending JP2025032089A (ja) 2018-02-12 2024-11-05 腫瘍微小環境を標的とするキメラ抗原受容体

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2024193719A Pending JP2025032089A (ja) 2018-02-12 2024-11-05 腫瘍微小環境を標的とするキメラ抗原受容体

Country Status (7)

Country Link
US (1) US20210038646A1 (https=)
EP (1) EP3752170A4 (https=)
JP (2) JP2021512635A (https=)
CN (1) CN111971053A (https=)
AU (1) AU2019218989B2 (https=)
CA (1) CA3090546A1 (https=)
WO (1) WO2019157533A1 (https=)

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US12378297B2 (en) 2017-04-14 2025-08-05 The General Hospital Corporation Chimeric antigen receptor T cells targeting the tumor microenvironment
CA3096458A1 (en) 2018-04-12 2019-10-17 Umoja Biopharma, Inc. Viral vectors and packaging cell lines
WO2020052645A1 (zh) * 2018-09-14 2020-03-19 上海原能细胞医学技术有限公司 表面包含免疫调节剂的细胞及其用途
WO2020232247A1 (en) 2019-05-14 2020-11-19 Provention Bio, Inc. Methods and compositions for preventing type 1 diabetes
JP7748935B2 (ja) * 2019-08-27 2025-10-03 ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア ＩＬ１３Ｒα２陽性ヒト腫瘍およびイヌ腫瘍を処置するための合成ＣＡＲ
CN112480263A (zh) * 2019-09-12 2021-03-12 普米斯生物技术(苏州)有限公司 一种双特异t细胞激活器活化t细胞的设计及其应用
CA3154281A1 (en) * 2019-10-16 2021-04-22 Andrew Scharenberg Retroviral vector for universal receptor therapy
EP4054602A4 (en) 2019-11-08 2023-12-06 Mayo Foundation for Medical Education and Research EPHA3 TARGETED CAR-T CELLS FOR TREATING TUMORS
CA3159050A1 (en) * 2019-11-21 2021-05-27 Jack A. Elias Bispecific antibodies against chi3l1 and ctla4 with enhanced cytotoxic effects on tumor cells
EP4138864A4 (en) * 2020-04-23 2024-07-10 Innovative Cellular Therapeutics Holdings, Ltd. Polyspecific binding molecules and their use in cell therapy
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IL298999A (en) 2020-06-11 2023-02-01 Provention Bio Inc Methods and compositions for the prevention of type 1 diabetes
EP4240832A4 (en) * 2020-11-04 2025-01-01 Fate Therapeutics, Inc. Engineered ipsc and immune effector cells for heterogenous tumor control
JP2023550148A (ja) * 2020-11-20 2023-11-30 シンシア・イノベーション・インコーポレイテッド がん免疫治療に用いられる武装二重ｃａｒ－ｔ組成物及び方法
EP4267604A1 (en) 2020-12-23 2023-11-01 Gadeta B.V. Chimeric, transmembrane proteins with bidirectional signalling activity
JP2024520444A (ja) 2021-05-24 2024-05-24 プロヴェンション・バイオ・インコーポレイテッド １型糖尿病を治療するための方法
CN115491358B (zh) * 2021-06-17 2024-09-06 复星凯特生物科技有限公司 一种靶向b7-h3和folr1双打靶点car t的制备及应用
WO2023274386A1 (zh) * 2021-07-01 2023-01-05 宁波茂行生物医药科技有限公司 靶向egfr的通用型car-t细胞及其制备方法
CN113969266B (zh) * 2021-10-26 2023-10-13 山东大学齐鲁医院 一种重组溶瘤腺病毒及其应用
WO2023081808A2 (en) * 2021-11-04 2023-05-11 The General Hospital Corporation Anti-mesothelin car t cells secreting teams and methods of use thereof
WO2024148216A2 (en) * 2023-01-05 2024-07-11 Neximmune, Inc. Combination therapy with t cell engager
WO2025080994A1 (en) * 2023-10-13 2025-04-17 The General Hospital Corporation Chimeric antigen receptor (car)-t cell engaging antibody molecule (team) formulations and pharmaceutical compositions
WO2025092689A1 (zh) * 2023-10-30 2025-05-08 苏州沙砾生物科技有限公司 一种表达多特异性抗原结合蛋白的细胞及其应用

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JP6647868B2 (ja) * 2013-02-20 2020-02-14 ノバルティス アーゲー ヒト化抗ＥＧＦＲｖＩＩＩキメラ抗原受容体を用いたがんの処置
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CN110582509A (zh) * 2017-01-31 2019-12-17 诺华股份有限公司 使用具有多特异性的嵌合t细胞受体蛋白治疗癌症
US12378297B2 (en) * 2017-04-14 2025-08-05 The General Hospital Corporation Chimeric antigen receptor T cells targeting the tumor microenvironment
JP2023539871A (ja) * 2020-08-26 2023-09-20 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア グリア芽細胞腫を処置するための方法および組成物

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