JP2024511423A5 - - Google Patents

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Publication number
JP2024511423A5
JP2024511423A5 JP2023558163A JP2023558163A JP2024511423A5 JP 2024511423 A5 JP2024511423 A5 JP 2024511423A5 JP 2023558163 A JP2023558163 A JP 2023558163A JP 2023558163 A JP2023558163 A JP 2023558163A JP 2024511423 A5 JP2024511423 A5 JP 2024511423A5
Authority
JP
Japan
Prior art keywords
cells
cell
chimeric receptor
recombinant
domain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023558163A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024511423A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/021605 external-priority patent/WO2022204324A1/en
Publication of JP2024511423A publication Critical patent/JP2024511423A/ja
Publication of JP2024511423A5 publication Critical patent/JP2024511423A5/ja
Pending legal-status Critical Current

Links

JP2023558163A 2021-03-24 2022-03-23 複数の転写調節因子をもつハイブリッド受容体 Pending JP2024511423A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163165428P 2021-03-24 2021-03-24
US63/165,428 2021-03-24
PCT/US2022/021605 WO2022204324A1 (en) 2021-03-24 2022-03-23 Hybrid receptors with multiple transcriptional regulators

Publications (2)

Publication Number Publication Date
JP2024511423A JP2024511423A (ja) 2024-03-13
JP2024511423A5 true JP2024511423A5 (https=) 2025-04-01

Family

ID=83396060

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023558163A Pending JP2024511423A (ja) 2021-03-24 2022-03-23 複数の転写調節因子をもつハイブリッド受容体

Country Status (7)

Country Link
US (1) US20240165163A1 (https=)
EP (1) EP4313111A4 (https=)
JP (1) JP2024511423A (https=)
CN (1) CN117597140A (https=)
AU (1) AU2022246086A1 (https=)
CA (1) CA3213189A1 (https=)
WO (1) WO2022204324A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114107253B (zh) * 2021-12-17 2024-03-15 复旦大学附属华山医院 一种利用工程细胞进行基因编辑的系统及方法
CN116676344A (zh) * 2023-05-31 2023-09-01 中国人民解放军总医院第八医学中心 稳定表达TGF-βII型受体的工程化巨噬细胞及其在肺纤维化治疗中的应用
CN119569893B (zh) * 2023-09-06 2025-10-31 上海恩凯细胞技术有限公司 特异性靶向肿瘤的嵌合抗原受体细胞及其制备方法和应用
CN117343908B (zh) * 2023-12-05 2024-02-09 南京大学 一种通过真菌精准激活的car-t细胞、制备方法、应用及药物组合物
WO2025240849A1 (en) * 2024-05-16 2025-11-20 The Brigham And Women's Hospital, Inc. Trem2 chimeric antigen receptors and uses thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102624023B1 (ko) * 2015-02-24 2024-01-11 더 리젠츠 오브 더 유니버시티 오브 캘리포니아 결합-촉발된 전사 스위치 및 이들의 이용 방법
IL260532B2 (en) * 2016-01-11 2023-12-01 Univ Leland Stanford Junior Chimeric proteins- containing systems and uses thereof in regulating gene expression
US12060394B2 (en) * 2016-04-28 2024-08-13 The Trustees Of Dartmouth College Nucleic acid constructs for co-expression of chimeric antigen receptor and transcription factor, cells containing and therapeutic use thereof
US12065479B2 (en) * 2017-11-16 2024-08-20 The Regents Of The University Of California Force sensor cleavage domain containing chimeric polypeptides and methods of use thereof
EP3741861A4 (en) * 2018-01-19 2021-12-08 Cafa Therapeutics Limited SYNNOTCH RECEPTOR REGULATED EXPRESSION OF IL12

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