JP2022548155A5 - - Google Patents
Info
- Publication number
- JP2022548155A5 JP2022548155A5 JP2022517166A JP2022517166A JP2022548155A5 JP 2022548155 A5 JP2022548155 A5 JP 2022548155A5 JP 2022517166 A JP2022517166 A JP 2022517166A JP 2022517166 A JP2022517166 A JP 2022517166A JP 2022548155 A5 JP2022548155 A5 JP 2022548155A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- alkyl
- linker
- compound
- radical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025095652A JP2025131780A (ja) | 2019-09-17 | 2025-06-09 | 線維芽細胞活性化タンパク質（ｆａｐ）を標的とする、がんならびに他の線維性疾患および炎症性疾患の画像化および治療の方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962901792P | 2019-09-17 | 2019-09-17 | |
| US62/901,792 | 2019-09-17 | ||
| PCT/US2020/051328 WO2021055641A1 (en) | 2019-09-17 | 2020-09-17 | Fibroblast activation protein (fap)-targeted imaging and therapy of cancers and other fibrotic and inflammatory diseases |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025095652A Division JP2025131780A (ja) | 2019-09-17 | 2025-06-09 | 線維芽細胞活性化タンパク質（ｆａｐ）を標的とする、がんならびに他の線維性疾患および炎症性疾患の画像化および治療の方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022548155A JP2022548155A (ja) | 2022-11-16 |
| JP2022548155A5 true JP2022548155A5 (enExample) | 2023-09-25 |
Family
ID=74883518
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022517166A Pending JP2022548155A (ja) | 2019-09-17 | 2020-09-17 | 線維芽細胞活性化タンパク質（ｆａｐ）を標的とする、がんならびに他の線維性疾患および炎症性疾患の画像化および治療の方法 |
| JP2025095652A Pending JP2025131780A (ja) | 2019-09-17 | 2025-06-09 | 線維芽細胞活性化タンパク質（ｆａｐ）を標的とする、がんならびに他の線維性疾患および炎症性疾患の画像化および治療の方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025095652A Pending JP2025131780A (ja) | 2019-09-17 | 2025-06-09 | 線維芽細胞活性化タンパク質（ｆａｐ）を標的とする、がんならびに他の線維性疾患および炎症性疾患の画像化および治療の方法 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20220409747A1 (enExample) |
| EP (1) | EP4031184A4 (enExample) |
| JP (2) | JP2022548155A (enExample) |
| KR (1) | KR20220066098A (enExample) |
| CN (1) | CN114901315B (enExample) |
| AU (2) | AU2020348781B2 (enExample) |
| BR (1) | BR112022005013A2 (enExample) |
| CA (1) | CA3150890A1 (enExample) |
| IL (1) | IL291386A (enExample) |
| MX (1) | MX2022003215A (enExample) |
| WO (1) | WO2021055641A1 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2934532B1 (en) | 2012-12-20 | 2019-10-23 | Purdue Research Foundation | Chimeric antigen receptor-expressing t cells as anti-cancer therapeutics |
| CA3019835A1 (en) | 2016-04-08 | 2017-10-12 | Purdue Research Foundation | Methods and compositions for car t cell therapy |
| CN110582288B (zh) | 2017-02-28 | 2024-09-20 | 恩多塞特公司 | 用于car t细胞疗法的组合物和方法 |
| WO2019144095A1 (en) | 2018-01-22 | 2019-07-25 | Seattle Children's Hospital (dba Seattle Children's Research Institute) | Methods of use for car t cells |
| JP7568224B2 (ja) | 2018-02-23 | 2024-10-16 | エンドサイト・インコーポレイテッド | Ｃａｒ ｔ細胞療法のための配列決定法 |
| US20230147962A1 (en) * | 2020-02-12 | 2023-05-11 | Philochem Ag | Fibroblast activation protein ligands for targeted delivery applications |
| EP4132921A4 (en) * | 2020-04-09 | 2024-03-27 | Purdue Research Foundation | Pi3 kinase inhibitors and uses thereof |
| US20230405153A1 (en) * | 2022-06-17 | 2023-12-21 | Purdue Research Foundation | Fibroblast activation protein-targeted magnetic resonance imaging agents, compositions, and methods of use |
| WO2023244828A1 (en) * | 2022-06-17 | 2023-12-21 | Purdue Research Foundation | Fibroblast activation protein-targeted nanoparticle magnetic resonance imaging agents |
| KR20260005224A (ko) * | 2023-03-10 | 2026-01-09 | 퍼듀 리서치 파운데이션 | 이중특이적 어댑터 및 종양의 치료 및 암-관련 섬유모세포의 억제에 있어서 이를 범용 car-t 세포와 함께 사용하는 용도 |
| CN122161839A (zh) * | 2024-08-23 | 2026-06-05 | 苏州博锐创合医药有限公司 | 基于环肽和共价弹头的化合物及其用途 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8071787B2 (en) * | 2009-03-13 | 2011-12-06 | National Health Research Institutes | Pyrrolidine compounds |
| CN103788071A (zh) * | 2012-11-01 | 2014-05-14 | 中国人民解放军第二军医大学 | N-(5-(喹啉-6-基)吡啶-3-基)苯磺酰胺衍生物、制备方法及治疗用途 |
| KR20180103166A (ko) * | 2016-01-29 | 2018-09-18 | 교와 핫꼬 기린 가부시키가이샤 | 핵산 복합체 |
| JP7162592B2 (ja) * | 2016-12-14 | 2022-10-28 | パーデュー・リサーチ・ファウンデイション | 線維芽細胞活性化タンパク質（ｆａｐ）標的イメージングおよび治療 |
| JP2021500373A (ja) * | 2017-10-23 | 2021-01-07 | ザ・ジョンズ・ホプキンス・ユニバーシティ | 線維芽細胞活性化タンパク質α（ＦＡＰ−α）を標的とする撮像剤および放射線療法用薬剤 |
| JP7037667B2 (ja) * | 2017-12-20 | 2022-03-16 | インスティチュート オブ オーガニック ケミストリー アンド バイオケミストリー エーエスシーアール，ヴイ．ヴイ．アイ． | Ｓｔｉｎｇアダプタータンパク質を活性化するホスホン酸結合を有する３’３’環状ジヌクレオチド |
| PH12020551205A1 (en) * | 2018-02-06 | 2021-04-19 | Univ Heidelberg | Fap inhibitors |
| WO2019154859A1 (en) * | 2018-02-06 | 2019-08-15 | Universität Heidelberg | Fap inhibitor |
| DE102018126558A1 (de) * | 2018-10-24 | 2020-04-30 | Helmholtz-Zentrum Dresden - Rossendorf E.V. | Markierungsvorläufer mit Quadratsäure-Kopplung |
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2020
- 2020-09-17 KR KR1020227012076A patent/KR20220066098A/ko active Pending
- 2020-09-17 US US17/761,508 patent/US20220409747A1/en active Pending
- 2020-09-17 AU AU2020348781A patent/AU2020348781B2/en active Active
- 2020-09-17 WO PCT/US2020/051328 patent/WO2021055641A1/en not_active Ceased
- 2020-09-17 MX MX2022003215A patent/MX2022003215A/es unknown
- 2020-09-17 CA CA3150890A patent/CA3150890A1/en active Pending
- 2020-09-17 EP EP20865602.5A patent/EP4031184A4/en active Pending
- 2020-09-17 BR BR112022005013A patent/BR112022005013A2/pt unknown
- 2020-09-17 JP JP2022517166A patent/JP2022548155A/ja active Pending
- 2020-09-17 CN CN202080079485.1A patent/CN114901315B/zh active Active
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2022
- 2022-03-15 IL IL291386A patent/IL291386A/en unknown
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2025
- 2025-06-09 JP JP2025095652A patent/JP2025131780A/ja active Pending
-
2026
- 2026-02-10 AU AU2026200943A patent/AU2026200943A1/en not_active Abandoned