JP2022548155A5 - - Google Patents
Info
- Publication number
- JP2022548155A5 JP2022548155A5 JP2022517166A JP2022517166A JP2022548155A5 JP 2022548155 A5 JP2022548155 A5 JP 2022548155A5 JP 2022517166 A JP2022517166 A JP 2022517166A JP 2022517166 A JP2022517166 A JP 2022517166A JP 2022548155 A5 JP2022548155 A5 JP 2022548155A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- alkyl
- linker
- compound
- radical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025095652A JP2025131780A (ja) | 2019-09-17 | 2025-06-09 | 線維芽細胞活性化タンパク質（ｆａｐ）を標的とする、がんならびに他の線維性疾患および炎症性疾患の画像化および治療の方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962901792P | 2019-09-17 | 2019-09-17 | |
| US62/901,792 | 2019-09-17 | ||
| PCT/US2020/051328 WO2021055641A1 (en) | 2019-09-17 | 2020-09-17 | Fibroblast activation protein (fap)-targeted imaging and therapy of cancers and other fibrotic and inflammatory diseases |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025095652A Division JP2025131780A (ja) | 2019-09-17 | 2025-06-09 | 線維芽細胞活性化タンパク質（ｆａｐ）を標的とする、がんならびに他の線維性疾患および炎症性疾患の画像化および治療の方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022548155A JP2022548155A (ja) | 2022-11-16 |
| JP2022548155A5 true JP2022548155A5 (enExample) | 2023-09-25 |
Family
ID=74883518
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022517166A Pending JP2022548155A (ja) | 2019-09-17 | 2020-09-17 | 線維芽細胞活性化タンパク質（ｆａｐ）を標的とする、がんならびに他の線維性疾患および炎症性疾患の画像化および治療の方法 |
| JP2025095652A Pending JP2025131780A (ja) | 2019-09-17 | 2025-06-09 | 線維芽細胞活性化タンパク質（ｆａｐ）を標的とする、がんならびに他の線維性疾患および炎症性疾患の画像化および治療の方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025095652A Pending JP2025131780A (ja) | 2019-09-17 | 2025-06-09 | 線維芽細胞活性化タンパク質（ｆａｐ）を標的とする、がんならびに他の線維性疾患および炎症性疾患の画像化および治療の方法 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20220409747A1 (enExample) |
| EP (1) | EP4031184A4 (enExample) |
| JP (2) | JP2022548155A (enExample) |
| KR (1) | KR20220066098A (enExample) |
| CN (1) | CN114901315B (enExample) |
| AU (2) | AU2020348781B2 (enExample) |
| BR (1) | BR112022005013A2 (enExample) |
| CA (1) | CA3150890A1 (enExample) |
| IL (1) | IL291386A (enExample) |
| MX (1) | MX2022003215A (enExample) |
| WO (1) | WO2021055641A1 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4282419A1 (en) | 2012-12-20 | 2023-11-29 | Purdue Research Foundation | Chimeric antigen receptor-expressing t cells as anti-cancer therapeutics |
| EP3439675A4 (en) | 2016-04-08 | 2019-12-18 | Purdue Research Foundation | METHOD AND COMPOSITIONS FOR CAR-T CELL THERAPY |
| WO2018160622A1 (en) | 2017-02-28 | 2018-09-07 | Endocyte, Inc. | Compositions and methods for car t cell therapy |
| US11311576B2 (en) | 2018-01-22 | 2022-04-26 | Seattle Children's Hospital | Methods of use for CAR T cells |
| AU2019225174B2 (en) | 2018-02-23 | 2025-11-20 | Endocyte, Inc. | Sequencing method for CAR T cell therapy |
| US20230147962A1 (en) * | 2020-02-12 | 2023-05-11 | Philochem Ag | Fibroblast activation protein ligands for targeted delivery applications |
| WO2021207682A2 (en) * | 2020-04-09 | 2021-10-14 | Philip Stewart Low | Pi3 kinase inhibitors and uses thereof |
| WO2023244828A1 (en) * | 2022-06-17 | 2023-12-21 | Purdue Research Foundation | Fibroblast activation protein-targeted nanoparticle magnetic resonance imaging agents |
| CN121079109A (zh) * | 2023-03-10 | 2025-12-05 | 普渡研究基金会 | 双特异性衔接子及其与通用car-t细胞在肿瘤治疗和癌症相关成纤维细胞抑制中的用途 |
| WO2026041108A1 (zh) * | 2024-08-23 | 2026-02-26 | 苏州博锐创合医药有限公司 | 基于环肽和共价弹头的化合物及其用途 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8071787B2 (en) * | 2009-03-13 | 2011-12-06 | National Health Research Institutes | Pyrrolidine compounds |
| CN103788071A (zh) * | 2012-11-01 | 2014-05-14 | 中国人民解放军第二军医大学 | N-(5-(喹啉-6-基)吡啶-3-基)苯磺酰胺衍生物、制备方法及治疗用途 |
| AU2017213404A1 (en) * | 2016-01-29 | 2018-09-20 | Kyowa Kirin Co., Ltd. | Nucleic acid conjugate |
| CN116474108A (zh) * | 2016-12-14 | 2023-07-25 | 普渡研究基金会 | 成纤维细胞活化蛋白(fap)-靶向成像和治疗 |
| EA202090776A1 (ru) * | 2017-10-23 | 2020-07-27 | Дзе Джонс Хопкинс Юниверсити | Визуализирующие и радиотерапевтические агенты, нацеленные на фибробласт-активирующий белок-альфа (fapalpha) |
| EP3728283B1 (en) * | 2017-12-20 | 2023-11-22 | Institute of Organic Chemistry and Biochemistry ASCR, V.V.I. | 3'3' cyclic dinucleotides with phosphonate bond activating the sting adaptor protein |
| EP3749663A1 (en) * | 2018-02-06 | 2020-12-16 | Universität Heidelberg | Fap inhibitor |
| WO2019154859A1 (en) * | 2018-02-06 | 2019-08-15 | Universität Heidelberg | Fap inhibitor |
| DE102018126558A1 (de) * | 2018-10-24 | 2020-04-30 | Helmholtz-Zentrum Dresden - Rossendorf E.V. | Markierungsvorläufer mit Quadratsäure-Kopplung |
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2020
- 2020-09-17 CN CN202080079485.1A patent/CN114901315B/zh active Active
- 2020-09-17 BR BR112022005013A patent/BR112022005013A2/pt unknown
- 2020-09-17 EP EP20865602.5A patent/EP4031184A4/en active Pending
- 2020-09-17 JP JP2022517166A patent/JP2022548155A/ja active Pending
- 2020-09-17 KR KR1020227012076A patent/KR20220066098A/ko active Pending
- 2020-09-17 WO PCT/US2020/051328 patent/WO2021055641A1/en not_active Ceased
- 2020-09-17 MX MX2022003215A patent/MX2022003215A/es unknown
- 2020-09-17 AU AU2020348781A patent/AU2020348781B2/en active Active
- 2020-09-17 US US17/761,508 patent/US20220409747A1/en active Pending
- 2020-09-17 CA CA3150890A patent/CA3150890A1/en active Pending
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2022
- 2022-03-15 IL IL291386A patent/IL291386A/en unknown
-
2025
- 2025-06-09 JP JP2025095652A patent/JP2025131780A/ja active Pending
-
2026
- 2026-02-10 AU AU2026200943A patent/AU2026200943A1/en not_active Abandoned