JP2024542178A5 - - Google Patents
Info
- Publication number
- JP2024542178A5 JP2024542178A5 JP2024527695A JP2024527695A JP2024542178A5 JP 2024542178 A5 JP2024542178 A5 JP 2024542178A5 JP 2024527695 A JP2024527695 A JP 2024527695A JP 2024527695 A JP2024527695 A JP 2024527695A JP 2024542178 A5 JP2024542178 A5 JP 2024542178A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- groups
- pharmaceutically acceptable
- membered
- stereoisomer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202111371514.4 | 2021-11-18 | ||
| CN202111371514 | 2021-11-18 | ||
| CN202210824373.5 | 2022-07-13 | ||
| CN202210824373 | 2022-07-13 | ||
| CN202211378992.2 | 2022-11-04 | ||
| CN202211378992 | 2022-11-04 | ||
| CN202211413934 | 2022-11-11 | ||
| CN202211413934.9 | 2022-11-11 | ||
| PCT/CN2022/132769 WO2023088406A1 (zh) | 2021-11-18 | 2022-11-18 | 稠合酰亚胺类衍生物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024542178A JP2024542178A (ja) | 2024-11-13 |
| JP2024542178A5 true JP2024542178A5 (enExample) | 2025-11-27 |
Family
ID=86396288
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024527695A Pending JP2024542178A (ja) | 2021-11-18 | 2022-11-18 | 縮合イミド誘導体 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20250152719A1 (enExample) |
| EP (1) | EP4434992A4 (enExample) |
| JP (1) | JP2024542178A (enExample) |
| KR (1) | KR20240107324A (enExample) |
| CN (2) | CN119823111B (enExample) |
| AU (1) | AU2022393875A1 (enExample) |
| CA (1) | CA3238118A1 (enExample) |
| IL (1) | IL312763A (enExample) |
| MX (1) | MX2024005702A (enExample) |
| TW (1) | TW202325300A (enExample) |
| WO (1) | WO2023088406A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2023325889A1 (en) * | 2022-08-19 | 2025-03-13 | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Compound containing cyclohexyl |
| KR20250128310A (ko) * | 2022-11-28 | 2025-08-27 | 상하이 데그론 바이오메디칼 테크놀로지 씨오., 엘티디. | Hur 조절 화합물 (elavl1) |
| TW202510854A (zh) | 2023-08-03 | 2025-03-16 | 大陸商西藏海思科製藥有限公司 | 多環並環btk降解劑及其在醫藥上的應用 |
| KR20260058836A (ko) | 2023-08-23 | 2026-04-29 | 치아타이 티안큉 파마수티컬 그룹 주식회사 | 사이클로부틸을 포함하는 화합물 |
| WO2025162254A1 (zh) | 2024-02-03 | 2025-08-07 | 正大天晴药业集团股份有限公司 | 包含三并环的化合物 |
| WO2025232888A1 (en) * | 2024-05-10 | 2025-11-13 | Shanghai Degron Biomedical Technology Co., Ltd. | Wee1 degraders and uses thereof |
| WO2026008044A1 (zh) * | 2024-07-05 | 2026-01-08 | 正大天晴药业集团股份有限公司 | 稠合酰亚胺类化合物及其应用 |
| WO2026026716A1 (zh) * | 2024-07-30 | 2026-02-05 | 深壶制药(山东)有限公司 | 恶唑或噻唑并吲哚类化合物或其衍生物及其应用 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10842878B2 (en) * | 2016-11-22 | 2020-11-24 | Dana-Farber Cancer Institute, Inc. | Degradation of Bruton's tyrosine kinase (BTK) by conjugation of BTK inhibitors with E3 ligase ligand and methods of use |
| IL319363A (en) * | 2017-01-31 | 2025-05-01 | Arvinas Operations Inc | Cervalon ligands and bifunctional compounds containing them |
| US11319330B2 (en) * | 2018-09-07 | 2022-05-03 | Medshine Discovery Inc. | Tricyclic furan-substituted piperidinedione compound |
| JP7098825B2 (ja) * | 2018-09-07 | 2022-07-11 | メッドシャイン ディスカバリー インコーポレイテッド | 三環式置換ピペリジンジオン類化合物 |
| BR112021004269A2 (pt) * | 2018-09-07 | 2021-05-25 | Chia Tai Tianqing Pharmaceutical Group Co., Ltd | composto de fórmula (i) ou um sal farmaceuticamente aceitável do mesmo, uso do mesmo, relacionada à proteína crbn e método para tratamento da mesma |
| EP3867242A1 (en) * | 2018-10-15 | 2021-08-25 | Nurix Therapeutics, Inc. | Bifunctional compounds for degrading btk via ubiquitin proteosome pathway |
| EP3924350A1 (en) * | 2019-02-13 | 2021-12-22 | Nurix Therapeutics, Inc. | Bifunctional compounds for degrading btk via ubiquitin proteosome pathway |
| WO2021018018A1 (en) * | 2019-07-26 | 2021-02-04 | Beigene, Ltd. | Degradation of bruton's tyrosine kinase (btk) by conjugation of btk inidbitors with e3 ligase ligand and methods of use |
| AU2020336381A1 (en) * | 2019-08-27 | 2022-03-03 | The Regents Of The University Of Michigan | Cereblon E3 ligase inhibitors |
| EP4031247A1 (en) * | 2019-09-16 | 2022-07-27 | Novartis AG | Bifunctional degraders and their methods of use |
| WO2021091575A1 (en) * | 2019-11-08 | 2021-05-14 | Nurix Therapeutics, Inc. | Bifunctional compounds for degrading btk via ubiquitin proteosome pathway |
| CN112812100B (zh) * | 2019-11-18 | 2022-04-05 | 四川海思科制药有限公司 | 一种具有降解btk激酶的化合物及其制备方法和药学上的应用 |
| CA3160713A1 (en) * | 2019-12-04 | 2021-06-10 | Nurix Therapeutics, Inc. | Bifunctional compounds for degrading btk via ubiquitin proteosome pathway |
| CN115380026B (zh) * | 2020-03-17 | 2023-11-07 | 南京明德新药研发有限公司 | 蛋白降解调节剂与其使用方法 |
| EP4146655A4 (en) * | 2020-04-30 | 2024-07-31 | BeiGene, Ltd. | DEGRADATION OF BRUTON TYROSINE KINASE (BTK) BY CONJUGATION OF BTK INHIBITORS WITH E3 LIGASE LIGAND AND METHOD OF USE |
-
2022
- 2022-11-18 CN CN202411790610.6A patent/CN119823111B/zh active Active
- 2022-11-18 WO PCT/CN2022/132769 patent/WO2023088406A1/zh not_active Ceased
- 2022-11-18 IL IL312763A patent/IL312763A/en unknown
- 2022-11-18 US US18/708,972 patent/US20250152719A1/en active Pending
- 2022-11-18 TW TW111144228A patent/TW202325300A/zh unknown
- 2022-11-18 CA CA3238118A patent/CA3238118A1/en active Pending
- 2022-11-18 MX MX2024005702A patent/MX2024005702A/es unknown
- 2022-11-18 EP EP22894936.8A patent/EP4434992A4/en active Pending
- 2022-11-18 JP JP2024527695A patent/JP2024542178A/ja active Pending
- 2022-11-18 KR KR1020247019045A patent/KR20240107324A/ko active Pending
- 2022-11-18 CN CN202280074055.XA patent/CN118201935A/zh active Pending
- 2022-11-18 AU AU2022393875A patent/AU2022393875A1/en active Pending
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