JP2022546387A5 - - Google Patents

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Publication number
JP2022546387A5
JP2022546387A5 JP2022512876A JP2022512876A JP2022546387A5 JP 2022546387 A5 JP2022546387 A5 JP 2022546387A5 JP 2022512876 A JP2022512876 A JP 2022512876A JP 2022512876 A JP2022512876 A JP 2022512876A JP 2022546387 A5 JP2022546387 A5 JP 2022546387A5
Authority
JP
Japan
Prior art keywords
pharmaceutical composition
antibody
composition according
icam1
linker
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022512876A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022546387A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2020/047300 external-priority patent/WO2021041171A1/en
Publication of JP2022546387A publication Critical patent/JP2022546387A/ja
Publication of JP2022546387A5 publication Critical patent/JP2022546387A5/ja
Priority to JP2025026469A priority Critical patent/JP2025104351A/ja
Pending legal-status Critical Current

Links

JP2022512876A 2019-08-23 2020-08-21 細胞間接着分子1(icam1)抗体薬物抱合体およびそれらの使用 Pending JP2022546387A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025026469A JP2025104351A (ja) 2019-08-23 2025-02-21 細胞間接着分子1(icam1)抗体薬物抱合体およびそれらの使用

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962891170P 2019-08-23 2019-08-23
US62/891,170 2019-08-23
PCT/US2020/047300 WO2021041171A1 (en) 2019-08-23 2020-08-21 Intercellular adhesion molecule 1 (icam1) antibody drug conjugate and uses thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025026469A Division JP2025104351A (ja) 2019-08-23 2025-02-21 細胞間接着分子1(icam1)抗体薬物抱合体およびそれらの使用

Publications (2)

Publication Number Publication Date
JP2022546387A JP2022546387A (ja) 2022-11-04
JP2022546387A5 true JP2022546387A5 (enExample) 2023-02-13

Family

ID=74684305

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2022512876A Pending JP2022546387A (ja) 2019-08-23 2020-08-21 細胞間接着分子1(icam1)抗体薬物抱合体およびそれらの使用
JP2025026469A Pending JP2025104351A (ja) 2019-08-23 2025-02-21 細胞間接着分子1(icam1)抗体薬物抱合体およびそれらの使用

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2025026469A Pending JP2025104351A (ja) 2019-08-23 2025-02-21 細胞間接着分子1(icam1)抗体薬物抱合体およびそれらの使用

Country Status (6)

Country Link
US (1) US20220280653A1 (enExample)
EP (1) EP4017532A4 (enExample)
JP (2) JP2022546387A (enExample)
CN (1) CN114929263A (enExample)
CA (1) CA3151800A1 (enExample)
WO (1) WO2021041171A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20170173005A1 (en) 2014-03-27 2017-06-22 Research Foundation Of The City University Of New York Method for detecting or treating triple negative breast cancer
US20240148888A1 (en) * 2021-02-23 2024-05-09 Children's Medical Center Corporation Intercellular adhesion molecule 1 (icam1) antibody drug conjugate and uses thereof
CN116920112A (zh) * 2022-03-30 2023-10-24 浙江省肿瘤医院 Icam1或其编码基因在制备胃癌治疗或诊断产品中的用途
CN115737835A (zh) * 2022-11-16 2023-03-07 浙江省肿瘤医院 特异性结合icam1的物质在制备甲状腺癌治疗或诊断产品中的用途

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008063479A2 (en) * 2006-11-17 2008-05-29 Fred Hutchinson Cancer Research Center Pancreatic cancer biomarkers
JPWO2012002388A1 (ja) * 2010-07-01 2013-08-29 国立大学法人信州大学 センチネルリンパ節への薬物輸送剤
CA2921982C (en) * 2013-09-02 2020-08-25 Hangzhou Dac Biotech Co., Ltd Novel cytotoxic agents for conjugation of drugs to cell binding molecule
CA2920192A1 (en) * 2013-09-27 2015-04-02 Immunomedics, Inc. Anti-trop-2 antibody-drug conjugates and uses thereof
JP6447933B2 (ja) * 2014-02-21 2019-01-09 アイビーシー ファーマスーティカルズ,インコーポレイテッド Trop−2発現細胞に対する免疫応答を誘発することによる疾患治療
SI3204018T1 (sl) * 2014-10-07 2021-11-30 Immunomedics, Inc. Neoadjuvantna uporaba konjugatov protitelo-zdravilo
WO2017139623A1 (en) * 2016-02-10 2017-08-17 Immunomedics, Inc. Combination of abcg2 inhibitors with sacituzumab govitecan (immu-132) overcomes resistance to sn-38 in trop-2 expressing cancers
AU2018333966B2 (en) * 2017-09-18 2025-04-03 Trustees Of Boston University Methods for treating NETosis and neutrophil activation

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