JP2024525624A5 - - Google Patents

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Publication number
JP2024525624A5
JP2024525624A5 JP2024500541A JP2024500541A JP2024525624A5 JP 2024525624 A5 JP2024525624 A5 JP 2024525624A5 JP 2024500541 A JP2024500541 A JP 2024500541A JP 2024500541 A JP2024500541 A JP 2024500541A JP 2024525624 A5 JP2024525624 A5 JP 2024525624A5
Authority
JP
Japan
Prior art keywords
antibody
drug conjugate
conjugate according
heavy chain
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024500541A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024525624A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/CN2022/103592 external-priority patent/WO2023280092A1/zh
Publication of JP2024525624A publication Critical patent/JP2024525624A/ja
Publication of JP2024525624A5 publication Critical patent/JP2024525624A5/ja
Pending legal-status Critical Current

Links

JP2024500541A 2021-07-05 2022-07-04 抗体薬物コンジュゲート及びその使用 Pending JP2024525624A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN202110757803.1 2021-07-05
CN202110757803 2021-07-05
PCT/CN2022/103592 WO2023280092A1 (zh) 2021-07-05 2022-07-04 抗体药物偶联物及其应用

Publications (2)

Publication Number Publication Date
JP2024525624A JP2024525624A (ja) 2024-07-12
JP2024525624A5 true JP2024525624A5 (enExample) 2025-06-23

Family

ID=84801059

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024500541A Pending JP2024525624A (ja) 2021-07-05 2022-07-04 抗体薬物コンジュゲート及びその使用

Country Status (5)

Country Link
US (1) US20240307551A1 (enExample)
EP (1) EP4386006A4 (enExample)
JP (1) JP2024525624A (enExample)
CN (1) CN117616052A (enExample)
WO (1) WO2023280092A1 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2024263367A1 (en) * 2023-04-27 2025-11-13 CSPC Megalith Biopharmaceutical Co., Ltd. Antibody-drug conjugate
CN116751319B (zh) * 2023-07-19 2024-11-05 首都医科大学 一种壳聚糖六肽衍生物及其制备方法和应用
CN120019819A (zh) * 2023-11-17 2025-05-20 成都康弘生物科技有限公司 双毒素抗体药物偶联物及其用途
WO2025113646A1 (zh) * 2023-11-30 2025-06-05 江苏康宁杰瑞生物制药有限公司 包含pd-l1结合分子与双特异性抗体-药物偶联物的组合物及其用途
WO2025242061A1 (zh) * 2024-05-21 2025-11-27 正大天晴药业集团股份有限公司 抗her2抗体药物偶联物治疗胆道癌的用途
WO2025247261A1 (zh) * 2024-05-30 2025-12-04 爱尔利希生物科技有限公司 抗egfr抗体药物偶联物及其用途
WO2025252039A1 (zh) * 2024-06-03 2025-12-11 正大天晴药业集团股份有限公司 抗her2抗体药物偶联物治疗非小细胞肺癌的用途
WO2026046156A1 (zh) * 2024-08-27 2026-03-05 江苏康宁杰瑞生物制药有限公司 连接子—毒素分子化合物的制备方法及其中间体
CN121109359A (zh) * 2024-11-20 2025-12-12 华中科技大学同济医学院附属协和医院 一种靶向降解蛋白及其应用

Family Cites Families (12)

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Publication number Priority date Publication date Assignee Title
DK1771482T3 (da) 2004-07-22 2014-10-20 Genentech Inc HER2-antistofsammensætning
CN102558355B (zh) 2011-12-31 2015-02-25 苏州康宁杰瑞生物科技有限公司 基于电荷网络的异二聚体fc改造方法及异二聚体蛋白的制备方法
CN102851338A (zh) 2012-07-25 2013-01-02 苏州康宁杰瑞生物科技有限公司 利用电荷排斥作用制备同二聚体蛋白混合物的方法
AU2014357292B2 (en) * 2013-11-27 2020-06-25 Zymeworks Bc Inc. Bispecific antigen-binding constructs targeting HER2
EP3083696B1 (en) * 2013-12-20 2018-02-14 F.Hoffmann-La Roche Ag Bispecific her2 antibodies and methods of use
SG11201608192SA (en) * 2014-04-11 2016-10-28 Medimmune Llc Bispecific her2 antibodies
CN110655582B (zh) * 2015-01-08 2022-12-16 江苏康宁杰瑞生物制药有限公司 具有共同轻链的双特异性抗体或抗体混合物
CN107446045A (zh) * 2016-07-22 2017-12-08 北京天广实生物技术股份有限公司 一种抗her2的抗体、其药物组合物及用途
CN113631580B (zh) * 2019-02-03 2024-07-02 上海宝济药业股份有限公司 抗her2的双特异性抗体及其应用
WO2021110107A1 (en) * 2019-12-04 2021-06-10 Jiangsu Alphamab Biopharmaceuticals Co., Ltd. COMBINATION OF BISPECIFIC FUSION PROTEIN AND ANTI-Her2 ANTIBODY FOR TUMOR TREATMENT
KR20220148200A (ko) * 2020-02-28 2022-11-04 리제너론 파마슈티칼스 인코포레이티드 Her2에 결합하는 이중특이적 항원 결합 분자 및 이의 사용 방법
EP4117729A4 (en) * 2020-04-15 2023-11-15 Shenzhen Enduring Biotech, Ltd. ANTIBODY DRUG CONJUGATE

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