JP2022545835A5 - - Google Patents
Info
- Publication number
- JP2022545835A5 JP2022545835A5 JP2022513569A JP2022513569A JP2022545835A5 JP 2022545835 A5 JP2022545835 A5 JP 2022545835A5 JP 2022513569 A JP2022513569 A JP 2022513569A JP 2022513569 A JP2022513569 A JP 2022513569A JP 2022545835 A5 JP2022545835 A5 JP 2022545835A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical product
- product according
- ted
- igf
- inhibitor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025101359A JP2025146837A (ja) | 2019-08-28 | 2025-06-17 | 甲状腺眼症の治療方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962892849P | 2019-08-28 | 2019-08-28 | |
| US62/892,849 | 2019-08-28 | ||
| PCT/US2020/048350 WO2021041773A1 (en) | 2019-08-28 | 2020-08-28 | Methods for the treatment of thyroid eye disease |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025101359A Division JP2025146837A (ja) | 2019-08-28 | 2025-06-17 | 甲状腺眼症の治療方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022545835A JP2022545835A (ja) | 2022-10-31 |
| JP2022545835A5 true JP2022545835A5 (enExample) | 2023-09-05 |
Family
ID=74686009
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022513569A Pending JP2022545835A (ja) | 2019-08-28 | 2020-08-28 | 甲状腺眼症の治療方法 |
| JP2025101359A Pending JP2025146837A (ja) | 2019-08-28 | 2025-06-17 | 甲状腺眼症の治療方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025101359A Pending JP2025146837A (ja) | 2019-08-28 | 2025-06-17 | 甲状腺眼症の治療方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US20210253719A1 (enExample) |
| EP (1) | EP4021500A4 (enExample) |
| JP (2) | JP2022545835A (enExample) |
| AU (1) | AU2020337958A1 (enExample) |
| BR (1) | BR112022003663A2 (enExample) |
| CA (1) | CA3152740A1 (enExample) |
| CO (1) | CO2022003582A2 (enExample) |
| WO (1) | WO2021041773A1 (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20170232024A1 (en) | 2014-08-04 | 2017-08-17 | Jerry Tan Eye Surgery Pte Ltd | Pharmaceutical compositions for demodex related blepharitis and eyelid crusting |
| CN119157876A (zh) | 2017-12-15 | 2024-12-20 | 塔苏斯制药有限公司 | 用于治疗睑炎的异恶唑啉驱虫剂制剂和方法 |
| US11208490B2 (en) | 2018-03-05 | 2021-12-28 | Horizon Therapeutics Ireland Dac | Methods for the treatment of thyroid eye disease |
| US12502377B2 (en) | 2019-04-04 | 2025-12-23 | Tarsus Pharmaceuticals, Inc. | Method of eradicating ticks that attach to humans using lotilaner formulations |
| JP2022545835A (ja) | 2019-08-28 | 2022-10-31 | ホライゾン セラピューティクス アイルランド デジグネイテッド アクティビティ カンパニー | 甲状腺眼症の治療方法 |
| CN113512116B (zh) * | 2020-04-10 | 2022-09-20 | 苏州普乐康医药科技有限公司 | 一种抗igf-1r抗体及其应用 |
| CA3195512A1 (en) * | 2020-10-14 | 2022-04-21 | Vahe Bedian | Compositions and methods for treatment of thyroid eye disease |
| CN113143928A (zh) * | 2021-04-02 | 2021-07-23 | 苏州普乐康医药科技有限公司 | 一种osi-906的应用 |
| JP2024531151A (ja) * | 2021-08-10 | 2024-08-29 | ビリジアン セラピューティクス, インコーポレイテッド | 甲状腺眼疾患の処置のための組成物、用量および方法 |
| CA3230426A1 (en) * | 2021-09-03 | 2023-03-09 | Novarock Biotherapeutics, Ltd. | Bispecific binding proteins that bind cd137 and a tumor associated antigen |
| JP2025520066A (ja) * | 2022-05-26 | 2025-07-01 | ホライゾン セラピューティクス アイルランド デジグネイテッド アクティビティ カンパニー | 甲状腺眼症の治療のための方法及び組成物 |
| TW202426502A (zh) * | 2022-09-30 | 2024-07-01 | 愛爾蘭商赫瑞森治療學愛爾蘭指定活動公司 | 治療不活躍甲狀腺眼病之方法 |
| CN122003247A (zh) * | 2023-07-07 | 2026-05-08 | 维里迪安治疗公司 | 治疗活动性和慢性甲状腺眼病的方法 |
| UY40826A (es) * | 2023-07-18 | 2025-01-31 | Horizon Therapeutics Ireland Dac | Inhibidores ra2s heterocíclicos de igf-1r para el tratamiento de enfermedades |
| CN121752595A (zh) | 2023-09-08 | 2026-03-27 | 北京拓界生物医药科技有限公司 | Igf-1r及tshr结合蛋白及其医药用途 |
| WO2025155888A1 (en) * | 2024-01-19 | 2025-07-24 | Sling Therapeutics, Inc. | Use of inhibitors of insulin-like growth factor receptor-1 for ocular-associated disorders |
Family Cites Families (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2373192A (en) | 1943-03-13 | 1945-04-10 | Walter M Lauer | Antioxidants |
| US4567253A (en) | 1984-02-03 | 1986-01-28 | Tony Durst | 2-Substituted derivatives of podophyllotoxin and etoposide |
| WO1995024190A2 (en) | 1994-03-07 | 1995-09-14 | Sugen, Inc. | Receptor tyrosine kinase inhibitors for inhibiting cell proliferative disorders and compositions thereof |
| US8153121B2 (en) | 2000-10-06 | 2012-04-10 | Los Angeles Biomedical Research Institute at Harbor—UCLA Medical Center | Diagnosis and therapy of antibody-mediated inflammatory autoimmune disorders |
| US8178304B2 (en) | 2000-10-06 | 2012-05-15 | Smith Terry J | Diagnostic methods relating to Graves' disease and other autoimmune disorders |
| NZ527302A (en) | 2001-01-05 | 2006-10-27 | Abgenix Inc | Antibodies to insulin-like growth factor I receptor |
| US7081454B2 (en) | 2001-03-28 | 2006-07-25 | Bristol-Myers Squibb Co. | Tyrosine kinase inhibitors |
| TWI238824B (en) | 2001-05-14 | 2005-09-01 | Novartis Ag | 4-amino-5-phenyl-7-cyclobutyl-pyrrolo[2,3-d]pyrimidine derivatives |
| US8188231B2 (en) | 2002-09-27 | 2012-05-29 | Xencor, Inc. | Optimized FC variants |
| US7317091B2 (en) | 2002-03-01 | 2008-01-08 | Xencor, Inc. | Optimized Fc variants |
| US7538195B2 (en) | 2002-06-14 | 2009-05-26 | Immunogen Inc. | Anti-IGF-I receptor antibody |
| US8084582B2 (en) | 2003-03-03 | 2011-12-27 | Xencor, Inc. | Optimized anti-CD20 monoclonal antibodies having Fc variants |
| EP2365001A3 (en) | 2003-05-01 | 2012-03-28 | Imclone LLC | Fully human antibodies directed against the human insulin-like growth factor-1 receptor |
| AR046071A1 (es) | 2003-07-10 | 2005-11-23 | Hoffmann La Roche | Anticuerpos contra el receptor i del factor de crecimiento de tipo insulinico y los usos de los mismos |
| US8101720B2 (en) | 2004-10-21 | 2012-01-24 | Xencor, Inc. | Immunoglobulin insertions, deletions and substitutions |
| WO2005058967A2 (en) | 2003-12-16 | 2005-06-30 | Pierre Fabre Medicament | Novel anti-insulin/igf-i hybrid receptor or anti-insulin/igf-i hybrid receptor and igf-ir antibodies and uses thereof |
| MXPA06011423A (es) | 2004-04-02 | 2007-01-23 | Osi Pharm Inc | Inhibidores de proteina cinasa heterobiciclica sustituida en el anillo 6,6-biciclico. |
| FR2873699B1 (fr) * | 2004-07-29 | 2009-08-21 | Pierre Fabre Medicament Sa | Nouveaux anticorps anti igf ir rt leurs utilisations |
| US8546543B2 (en) | 2004-11-12 | 2013-10-01 | Xencor, Inc. | Fc variants that extend antibody half-life |
| US8367805B2 (en) | 2004-11-12 | 2013-02-05 | Xencor, Inc. | Fc variants with altered binding to FcRn |
| MY146381A (en) | 2004-12-22 | 2012-08-15 | Amgen Inc | Compositions and methods relating relating to anti-igf-1 receptor antibodies |
| ES2426482T3 (es) | 2005-01-27 | 2013-10-23 | Kyowa Hakko Kirin Co., Ltd. | Inhibidor de IGF-1R |
| PL1979001T3 (pl) | 2005-12-13 | 2012-09-28 | Medimmune Ltd | Białka wiążące specyficzne dla insulinopodobnych czynników wzrostu i ich zastosowania |
| US7772231B2 (en) | 2005-12-29 | 2010-08-10 | Abbott Laboratories | Substituted pyrazolo[3,4-d]pyrimidines as protein kinase inhibitors |
| JP2009532027A (ja) | 2006-03-28 | 2009-09-10 | バイオジェン・アイデック・エムエイ・インコーポレイテッド | 抗igf−1r抗体およびその使用 |
| AU2007269540B2 (en) | 2006-07-05 | 2013-06-27 | Exelixis, Inc. | Methods of using IGF1R and Abl kinase modulators |
| SI2041138T1 (sl) | 2006-07-07 | 2014-08-29 | Bristol-Myers Squibb Company | Pirolotriazin kinazni inhibitorji |
| US8063225B2 (en) | 2006-08-14 | 2011-11-22 | Chembridge Corporation | Tricyclic compound derivatives useful in the treatment of neoplastic diseases, inflammatory disorders and immunomodulatory disorders |
| AU2007313077B2 (en) | 2006-10-17 | 2011-06-02 | Neothetics, Inc. | Methods, compositions, and formulations for the treatment of thyroid eye disease |
| BRPI0811898A2 (pt) | 2007-06-01 | 2019-09-24 | Glaxosmithkline Llc | composto, composição farmacêutica, métodos para tratar um neoplasma suscetível e um câncer em um mamífero, processo para preparar um composto, e, uso de um composto. |
| EP2188292B1 (en) | 2007-08-08 | 2013-05-29 | GlaxoSmithKline Intellectual Property Development Limited | 2- [ (2-{phenylamino}-1h-pyrrolo [2, 3-d]pyrimidin-4-yl) amino]benzamide derivatives as igf-1r inhibitors for the treatment of cancer |
| JP2010537985A (ja) * | 2007-08-28 | 2010-12-09 | バイオジェン アイデック マサチューセッツ インコーポレイテッド | 抗igf−1r抗体およびその使用 |
| WO2011158931A1 (ja) | 2010-06-17 | 2011-12-22 | 協和発酵キリン株式会社 | インダゾール誘導体の有用な塩 |
| US9062046B2 (en) | 2010-07-16 | 2015-06-23 | Piramal Enterprises Limited | Substituted imidazoquinoline derivatives as kinase inhibitors |
| UY33539A (es) | 2010-08-02 | 2012-02-29 | Astrazeneca Ab | Compuestos químicos alk |
| US8546443B2 (en) | 2010-12-21 | 2013-10-01 | Boehringer Ingelheim International Gmbh | Benzylic oxindole pyrimidines |
| MX336197B (es) | 2011-04-19 | 2016-01-11 | Merrimack Pharmaceuticals Inc | Anicuerpos anti-igf-1r y anti-erbb3 monoespecificos y biespecificos. |
| WO2012143879A1 (en) | 2011-04-21 | 2012-10-26 | Piramal Healthcare Limited | A crystalline form of a salt of a morpholino sulfonyl indole derivative and a process for its preparation |
| EP2807166B1 (en) | 2012-01-23 | 2016-04-06 | Boehringer Ingelheim International GmbH | 5,8-dihydro-6h-pyrazolo[3,4-h]quinazolines as igf-1r/ir inhibitors |
| US20140255413A1 (en) | 2013-03-07 | 2014-09-11 | Boehringer Ingelheim International Gmbh | Combination therapy for neoplasia treatment |
| WO2016064716A1 (en) | 2014-10-20 | 2016-04-28 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Combination therapy of tshr antagonist and igfr inhibitor |
| WO2016180843A1 (en) | 2015-05-13 | 2016-11-17 | Boehringer Ingelheim International Gmbh | New 5,8-dimethyl-9-phenyl-5,8-dihydro-6h-pyrazolo[3,4-h]quinazolin-2- yl)-(1 h-pyrazol-3-yl)-amines and derivatives as igf-1 r/ir inhibitors |
| US11208489B2 (en) | 2018-01-24 | 2021-12-28 | Horizon Therapeutics Ireland Dac | Methods for the treatment of thyroid eye disease |
| US20210284741A1 (en) * | 2018-01-24 | 2021-09-16 | Hznp Limited | Methods for the treatment of thyroid eye disease |
| US11208490B2 (en) | 2018-03-05 | 2021-12-28 | Horizon Therapeutics Ireland Dac | Methods for the treatment of thyroid eye disease |
| US10457740B1 (en) * | 2018-01-29 | 2019-10-29 | Flagship Pioneering Innovations V, Inc. | Methods and compositions for treating cancer using P2RX2 inhibitors |
| JP2022545835A (ja) | 2019-08-28 | 2022-10-31 | ホライゾン セラピューティクス アイルランド デジグネイテッド アクティビティ カンパニー | 甲状腺眼症の治療方法 |
-
2020
- 2020-08-28 JP JP2022513569A patent/JP2022545835A/ja active Pending
- 2020-08-28 EP EP20858844.2A patent/EP4021500A4/en active Pending
- 2020-08-28 CA CA3152740A patent/CA3152740A1/en active Pending
- 2020-08-28 WO PCT/US2020/048350 patent/WO2021041773A1/en not_active Ceased
- 2020-08-28 AU AU2020337958A patent/AU2020337958A1/en active Pending
- 2020-08-28 BR BR112022003663A patent/BR112022003663A2/pt unknown
-
2021
- 2021-03-03 US US17/191,651 patent/US20210253719A1/en not_active Abandoned
-
2022
- 2022-03-10 US US17/654,318 patent/US12600787B2/en active Active
- 2022-03-25 CO CONC2022/0003582A patent/CO2022003582A2/es unknown
-
2025
- 2025-06-17 JP JP2025101359A patent/JP2025146837A/ja active Pending
-
2026
- 2026-04-06 US US19/639,842 patent/US20260217838A1/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN1191859C (zh) | 用于治疗癌症的泰素帝和重组人源化her2单克隆抗体的组合 | |
| JP2023002662A5 (enExample) | ||
| TW202327597A (zh) | 一種ezh2抑制劑用於製備治療t細胞淋巴瘤的藥物的用途 | |
| JP2006523216A5 (enExample) | ||
| IL178745A (en) | Use of 4- (amino) -2 (2, 6-dioxo (3-piperidyl)) -isoindoline -1, 3-discussion of preparation of a medical vaccine for the treatment of myeloma | |
| JP2007515469A5 (enExample) | ||
| WO2019096194A1 (zh) | Pd-1抗体和vegfr抑制剂联合治疗小细胞肺癌的用途 | |
| JP2017031160A5 (enExample) | ||
| JP2015526458A5 (enExample) | ||
| JP2017061561A (ja) | ニタゾキサニドの制御放出医薬配合物 | |
| JP2023530316A5 (enExample) | ||
| WO2011087066A1 (ja) | 眼内血管新生及び/又は眼内血管透過性亢進を伴う疾患の予防又は治療のための医薬 | |
| CA3188345A1 (en) | Combination of zibotentan and dapagliflozin for the treatment of chronic kidney disease | |
| US20210260025A1 (en) | Capsid assembly modulator dosing regimen | |
| JP2022550919A5 (enExample) | ||
| JP2018531273A5 (enExample) | ||
| JP2016528240A (ja) | ドルテグラビル、エムトリシタビン及びテノホビルの医薬コンビネーションを有する医薬 | |
| JP2022116304A (ja) | 血液がんの治療のためのPPARγアゴニスト | |
| JP2015517523A5 (enExample) | ||
| RU2494736C2 (ru) | Комбинация, включающая паклитаксел, для лечения рака яичников | |
| JP2023537921A5 (enExample) | ||
| CA3177685A1 (en) | Tlr7/8 antagonists for the treatment of coronavirus infections | |
| JP2019534251A5 (enExample) | ||
| JP2024525164A5 (enExample) | ||
| JP2025509278A5 (enExample) |