JP2022545835A5 - - Google Patents

Info

Publication number
JP2022545835A5
JP2022545835A5 JP2022513569A JP2022513569A JP2022545835A5 JP 2022545835 A5 JP2022545835 A5 JP 2022545835A5 JP 2022513569 A JP2022513569 A JP 2022513569A JP 2022513569 A JP2022513569 A JP 2022513569A JP 2022545835 A5 JP2022545835 A5 JP 2022545835A5
Authority
JP
Japan
Prior art keywords
pharmaceutical product
product according
ted
igf
inhibitor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022513569A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022545835A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2020/048350 external-priority patent/WO2021041773A1/en
Publication of JP2022545835A publication Critical patent/JP2022545835A/ja
Publication of JP2022545835A5 publication Critical patent/JP2022545835A5/ja
Priority to JP2025101359A priority Critical patent/JP2025146837A/ja
Pending legal-status Critical Current

Links

JP2022513569A 2019-08-28 2020-08-28 甲状腺眼症の治療方法 Pending JP2022545835A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025101359A JP2025146837A (ja) 2019-08-28 2025-06-17 甲状腺眼症の治療方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962892849P 2019-08-28 2019-08-28
US62/892,849 2019-08-28
PCT/US2020/048350 WO2021041773A1 (en) 2019-08-28 2020-08-28 Methods for the treatment of thyroid eye disease

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025101359A Division JP2025146837A (ja) 2019-08-28 2025-06-17 甲状腺眼症の治療方法

Publications (2)

Publication Number Publication Date
JP2022545835A JP2022545835A (ja) 2022-10-31
JP2022545835A5 true JP2022545835A5 (enExample) 2023-09-05

Family

ID=74686009

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2022513569A Pending JP2022545835A (ja) 2019-08-28 2020-08-28 甲状腺眼症の治療方法
JP2025101359A Pending JP2025146837A (ja) 2019-08-28 2025-06-17 甲状腺眼症の治療方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2025101359A Pending JP2025146837A (ja) 2019-08-28 2025-06-17 甲状腺眼症の治療方法

Country Status (8)

Country Link
US (3) US20210253719A1 (enExample)
EP (1) EP4021500A4 (enExample)
JP (2) JP2022545835A (enExample)
AU (1) AU2020337958A1 (enExample)
BR (1) BR112022003663A2 (enExample)
CA (1) CA3152740A1 (enExample)
CO (1) CO2022003582A2 (enExample)
WO (1) WO2021041773A1 (enExample)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20170232024A1 (en) 2014-08-04 2017-08-17 Jerry Tan Eye Surgery Pte Ltd Pharmaceutical compositions for demodex related blepharitis and eyelid crusting
CN119157876A (zh) 2017-12-15 2024-12-20 塔苏斯制药有限公司 用于治疗睑炎的异恶唑啉驱虫剂制剂和方法
US11208490B2 (en) 2018-03-05 2021-12-28 Horizon Therapeutics Ireland Dac Methods for the treatment of thyroid eye disease
US12502377B2 (en) 2019-04-04 2025-12-23 Tarsus Pharmaceuticals, Inc. Method of eradicating ticks that attach to humans using lotilaner formulations
JP2022545835A (ja) 2019-08-28 2022-10-31 ホライゾン セラピューティクス アイルランド デジグネイテッド アクティビティ カンパニー 甲状腺眼症の治療方法
CN113512116B (zh) * 2020-04-10 2022-09-20 苏州普乐康医药科技有限公司 一种抗igf-1r抗体及其应用
CA3195512A1 (en) * 2020-10-14 2022-04-21 Vahe Bedian Compositions and methods for treatment of thyroid eye disease
CN113143928A (zh) * 2021-04-02 2021-07-23 苏州普乐康医药科技有限公司 一种osi-906的应用
JP2024531151A (ja) * 2021-08-10 2024-08-29 ビリジアン セラピューティクス, インコーポレイテッド 甲状腺眼疾患の処置のための組成物、用量および方法
CA3230426A1 (en) * 2021-09-03 2023-03-09 Novarock Biotherapeutics, Ltd. Bispecific binding proteins that bind cd137 and a tumor associated antigen
JP2025520066A (ja) * 2022-05-26 2025-07-01 ホライゾン セラピューティクス アイルランド デジグネイテッド アクティビティ カンパニー 甲状腺眼症の治療のための方法及び組成物
TW202426502A (zh) * 2022-09-30 2024-07-01 愛爾蘭商赫瑞森治療學愛爾蘭指定活動公司 治療不活躍甲狀腺眼病之方法
CN122003247A (zh) * 2023-07-07 2026-05-08 维里迪安治疗公司 治疗活动性和慢性甲状腺眼病的方法
UY40826A (es) * 2023-07-18 2025-01-31 Horizon Therapeutics Ireland Dac Inhibidores ra2s heterocíclicos de igf-1r para el tratamiento de enfermedades
CN121752595A (zh) 2023-09-08 2026-03-27 北京拓界生物医药科技有限公司 Igf-1r及tshr结合蛋白及其医药用途
WO2025155888A1 (en) * 2024-01-19 2025-07-24 Sling Therapeutics, Inc. Use of inhibitors of insulin-like growth factor receptor-1 for ocular-associated disorders

Family Cites Families (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2373192A (en) 1943-03-13 1945-04-10 Walter M Lauer Antioxidants
US4567253A (en) 1984-02-03 1986-01-28 Tony Durst 2-Substituted derivatives of podophyllotoxin and etoposide
WO1995024190A2 (en) 1994-03-07 1995-09-14 Sugen, Inc. Receptor tyrosine kinase inhibitors for inhibiting cell proliferative disorders and compositions thereof
US8153121B2 (en) 2000-10-06 2012-04-10 Los Angeles Biomedical Research Institute at Harbor—UCLA Medical Center Diagnosis and therapy of antibody-mediated inflammatory autoimmune disorders
US8178304B2 (en) 2000-10-06 2012-05-15 Smith Terry J Diagnostic methods relating to Graves' disease and other autoimmune disorders
NZ527302A (en) 2001-01-05 2006-10-27 Abgenix Inc Antibodies to insulin-like growth factor I receptor
US7081454B2 (en) 2001-03-28 2006-07-25 Bristol-Myers Squibb Co. Tyrosine kinase inhibitors
TWI238824B (en) 2001-05-14 2005-09-01 Novartis Ag 4-amino-5-phenyl-7-cyclobutyl-pyrrolo[2,3-d]pyrimidine derivatives
US8188231B2 (en) 2002-09-27 2012-05-29 Xencor, Inc. Optimized FC variants
US7317091B2 (en) 2002-03-01 2008-01-08 Xencor, Inc. Optimized Fc variants
US7538195B2 (en) 2002-06-14 2009-05-26 Immunogen Inc. Anti-IGF-I receptor antibody
US8084582B2 (en) 2003-03-03 2011-12-27 Xencor, Inc. Optimized anti-CD20 monoclonal antibodies having Fc variants
EP2365001A3 (en) 2003-05-01 2012-03-28 Imclone LLC Fully human antibodies directed against the human insulin-like growth factor-1 receptor
AR046071A1 (es) 2003-07-10 2005-11-23 Hoffmann La Roche Anticuerpos contra el receptor i del factor de crecimiento de tipo insulinico y los usos de los mismos
US8101720B2 (en) 2004-10-21 2012-01-24 Xencor, Inc. Immunoglobulin insertions, deletions and substitutions
WO2005058967A2 (en) 2003-12-16 2005-06-30 Pierre Fabre Medicament Novel anti-insulin/igf-i hybrid receptor or anti-insulin/igf-i hybrid receptor and igf-ir antibodies and uses thereof
MXPA06011423A (es) 2004-04-02 2007-01-23 Osi Pharm Inc Inhibidores de proteina cinasa heterobiciclica sustituida en el anillo 6,6-biciclico.
FR2873699B1 (fr) * 2004-07-29 2009-08-21 Pierre Fabre Medicament Sa Nouveaux anticorps anti igf ir rt leurs utilisations
US8546543B2 (en) 2004-11-12 2013-10-01 Xencor, Inc. Fc variants that extend antibody half-life
US8367805B2 (en) 2004-11-12 2013-02-05 Xencor, Inc. Fc variants with altered binding to FcRn
MY146381A (en) 2004-12-22 2012-08-15 Amgen Inc Compositions and methods relating relating to anti-igf-1 receptor antibodies
ES2426482T3 (es) 2005-01-27 2013-10-23 Kyowa Hakko Kirin Co., Ltd. Inhibidor de IGF-1R
PL1979001T3 (pl) 2005-12-13 2012-09-28 Medimmune Ltd Białka wiążące specyficzne dla insulinopodobnych czynników wzrostu i ich zastosowania
US7772231B2 (en) 2005-12-29 2010-08-10 Abbott Laboratories Substituted pyrazolo[3,4-d]pyrimidines as protein kinase inhibitors
JP2009532027A (ja) 2006-03-28 2009-09-10 バイオジェン・アイデック・エムエイ・インコーポレイテッド 抗igf−1r抗体およびその使用
AU2007269540B2 (en) 2006-07-05 2013-06-27 Exelixis, Inc. Methods of using IGF1R and Abl kinase modulators
SI2041138T1 (sl) 2006-07-07 2014-08-29 Bristol-Myers Squibb Company Pirolotriazin kinazni inhibitorji
US8063225B2 (en) 2006-08-14 2011-11-22 Chembridge Corporation Tricyclic compound derivatives useful in the treatment of neoplastic diseases, inflammatory disorders and immunomodulatory disorders
AU2007313077B2 (en) 2006-10-17 2011-06-02 Neothetics, Inc. Methods, compositions, and formulations for the treatment of thyroid eye disease
BRPI0811898A2 (pt) 2007-06-01 2019-09-24 Glaxosmithkline Llc composto, composição farmacêutica, métodos para tratar um neoplasma suscetível e um câncer em um mamífero, processo para preparar um composto, e, uso de um composto.
EP2188292B1 (en) 2007-08-08 2013-05-29 GlaxoSmithKline Intellectual Property Development Limited 2- [ (2-{phenylamino}-1h-pyrrolo [2, 3-d]pyrimidin-4-yl) amino]benzamide derivatives as igf-1r inhibitors for the treatment of cancer
JP2010537985A (ja) * 2007-08-28 2010-12-09 バイオジェン アイデック マサチューセッツ インコーポレイテッド 抗igf−1r抗体およびその使用
WO2011158931A1 (ja) 2010-06-17 2011-12-22 協和発酵キリン株式会社 インダゾール誘導体の有用な塩
US9062046B2 (en) 2010-07-16 2015-06-23 Piramal Enterprises Limited Substituted imidazoquinoline derivatives as kinase inhibitors
UY33539A (es) 2010-08-02 2012-02-29 Astrazeneca Ab Compuestos químicos alk
US8546443B2 (en) 2010-12-21 2013-10-01 Boehringer Ingelheim International Gmbh Benzylic oxindole pyrimidines
MX336197B (es) 2011-04-19 2016-01-11 Merrimack Pharmaceuticals Inc Anicuerpos anti-igf-1r y anti-erbb3 monoespecificos y biespecificos.
WO2012143879A1 (en) 2011-04-21 2012-10-26 Piramal Healthcare Limited A crystalline form of a salt of a morpholino sulfonyl indole derivative and a process for its preparation
EP2807166B1 (en) 2012-01-23 2016-04-06 Boehringer Ingelheim International GmbH 5,8-dihydro-6h-pyrazolo[3,4-h]quinazolines as igf-1r/ir inhibitors
US20140255413A1 (en) 2013-03-07 2014-09-11 Boehringer Ingelheim International Gmbh Combination therapy for neoplasia treatment
WO2016064716A1 (en) 2014-10-20 2016-04-28 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Combination therapy of tshr antagonist and igfr inhibitor
WO2016180843A1 (en) 2015-05-13 2016-11-17 Boehringer Ingelheim International Gmbh New 5,8-dimethyl-9-phenyl-5,8-dihydro-6h-pyrazolo[3,4-h]quinazolin-2- yl)-(1 h-pyrazol-3-yl)-amines and derivatives as igf-1 r/ir inhibitors
US11208489B2 (en) 2018-01-24 2021-12-28 Horizon Therapeutics Ireland Dac Methods for the treatment of thyroid eye disease
US20210284741A1 (en) * 2018-01-24 2021-09-16 Hznp Limited Methods for the treatment of thyroid eye disease
US11208490B2 (en) 2018-03-05 2021-12-28 Horizon Therapeutics Ireland Dac Methods for the treatment of thyroid eye disease
US10457740B1 (en) * 2018-01-29 2019-10-29 Flagship Pioneering Innovations V, Inc. Methods and compositions for treating cancer using P2RX2 inhibitors
JP2022545835A (ja) 2019-08-28 2022-10-31 ホライゾン セラピューティクス アイルランド デジグネイテッド アクティビティ カンパニー 甲状腺眼症の治療方法

Similar Documents

Publication Publication Date Title
CN1191859C (zh) 用于治疗癌症的泰素帝和重组人源化her2单克隆抗体的组合
JP2023002662A5 (enExample)
TW202327597A (zh) 一種ezh2抑制劑用於製備治療t細胞淋巴瘤的藥物的用途
JP2006523216A5 (enExample)
IL178745A (en) Use of 4- (amino) -2 (2, 6-dioxo (3-piperidyl)) -isoindoline -1, 3-discussion of preparation of a medical vaccine for the treatment of myeloma
JP2007515469A5 (enExample)
WO2019096194A1 (zh) Pd-1抗体和vegfr抑制剂联合治疗小细胞肺癌的用途
JP2017031160A5 (enExample)
JP2015526458A5 (enExample)
JP2017061561A (ja) ニタゾキサニドの制御放出医薬配合物
JP2023530316A5 (enExample)
WO2011087066A1 (ja) 眼内血管新生及び/又は眼内血管透過性亢進を伴う疾患の予防又は治療のための医薬
CA3188345A1 (en) Combination of zibotentan and dapagliflozin for the treatment of chronic kidney disease
US20210260025A1 (en) Capsid assembly modulator dosing regimen
JP2022550919A5 (enExample)
JP2018531273A5 (enExample)
JP2016528240A (ja) ドルテグラビル、エムトリシタビン及びテノホビルの医薬コンビネーションを有する医薬
JP2022116304A (ja) 血液がんの治療のためのPPARγアゴニスト
JP2015517523A5 (enExample)
RU2494736C2 (ru) Комбинация, включающая паклитаксел, для лечения рака яичников
JP2023537921A5 (enExample)
CA3177685A1 (en) Tlr7/8 antagonists for the treatment of coronavirus infections
JP2019534251A5 (enExample)
JP2024525164A5 (enExample)
JP2025509278A5 (enExample)