JP2022545516A5 - - Google Patents
Info
- Publication number
- JP2022545516A5 JP2022545516A5 JP2022512466A JP2022512466A JP2022545516A5 JP 2022545516 A5 JP2022545516 A5 JP 2022545516A5 JP 2022512466 A JP2022512466 A JP 2022512466A JP 2022512466 A JP2022512466 A JP 2022512466A JP 2022545516 A5 JP2022545516 A5 JP 2022545516A5
- Authority
- JP
- Japan
- Prior art keywords
- cells
- signaling pathway
- pathway activator
- visceral
- mesoderm cells
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962892781P | 2019-08-28 | 2019-08-28 | |
| US62/892,781 | 2019-08-28 | ||
| PCT/US2020/047846 WO2021041443A2 (en) | 2019-08-28 | 2020-08-25 | Organoid mesoderm lineage diversification |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022545516A JP2022545516A (ja) | 2022-10-27 |
| JP2022545516A5 true JP2022545516A5 (https=) | 2024-02-06 |
| JP7780423B2 JP7780423B2 (ja) | 2025-12-04 |
Family
ID=74685212
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022512466A Active JP7780423B2 (ja) | 2019-08-28 | 2020-08-25 | オルガノイド中胚葉系統多様化 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20220275341A1 (https=) |
| EP (1) | EP4022036A4 (https=) |
| JP (1) | JP7780423B2 (https=) |
| CN (1) | CN114430774A (https=) |
| AU (1) | AU2020337417A1 (https=) |
| CA (1) | CA3150015A1 (https=) |
| WO (1) | WO2021041443A2 (https=) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9719068B2 (en) | 2010-05-06 | 2017-08-01 | Children's Hospital Medical Center | Methods and systems for converting precursor cells into intestinal tissues through directed differentiation |
| SG10201801654RA (en) | 2014-05-28 | 2018-04-27 | Childrens Hospital Med Ct | Methods and systems for converting precursor cells into gastric tissues through directed differentiation |
| EP4553082A3 (en) | 2016-11-04 | 2025-08-20 | Children's Hospital Medical Center | Liver organoid compositions and methods of making and using same |
| JP7248586B2 (ja) | 2017-04-14 | 2023-03-29 | チルドレンズ ホスピタル メディカル センター | 複数ドナー幹細胞組成物およびそれを作製する方法 |
| EP3694603B1 (en) | 2017-10-10 | 2026-04-08 | Children's Hospital Medical Center | Esophageal tissue and/or organoid compositions and methods of making same |
| EP3727394A4 (en) | 2017-12-21 | 2021-09-08 | Children's Hospital Medical Center | DIGITALIZED HUMAN ORGANOIDS AND METHOD OF USING THEREOF |
| EP4678727A3 (en) | 2018-07-26 | 2026-03-11 | Children's Hospital Medical Center | Hepato-biliary-pancreatic tissues and methods of making same |
| CA3112026A1 (en) | 2018-09-12 | 2020-03-19 | Children's Hospital Medical Center | Organoid compositions for the production of hematopoietic stem cells and derivatives thereof |
| US12600943B2 (en) | 2019-02-01 | 2026-04-14 | The University Of Hong Kong | Innervated organoid compositions and methods of making same |
| AU2020283048A1 (en) | 2019-05-31 | 2021-12-23 | Children's Hospital Medical Center | Shaped organoid compositions and methods of making same |
| US12497597B2 (en) | 2019-05-31 | 2025-12-16 | Children's Hospital Medical Center | Methods of generating and expanding hematopoietic stem cells |
| WO2022066772A1 (en) * | 2020-09-25 | 2022-03-31 | Children´S Hospital Medical Center | Raft cultures and methods of making thereof |
| EP4440586A4 (en) * | 2021-12-03 | 2026-02-11 | Childrens Hospital Med Ct | IMPROVED METHODS FOR PREPARING DIFFERENT TYPES OF MESODERM CELLS |
| WO2024123790A1 (en) * | 2022-12-07 | 2024-06-13 | The Board Of Trustees Of The Leland Stanford Junior University | A method to generate cardiac pericytes from human induced pluripotent stem cells |
| CN116259364A (zh) * | 2022-12-19 | 2023-06-13 | 湖南大学 | 一种基于时间序列单细胞转录组测序数据的细胞轨迹推断方法 |
| WO2025072803A1 (en) | 2023-09-29 | 2025-04-03 | Children's Hospital Medical Center | Ntrk2 signaling-mediated alveolar capillary injury and repair |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1768133A (zh) * | 2003-01-31 | 2006-05-03 | 加利福尼亚大学董事会 | 使用islet1作为标志分离或产生干细胞 |
| US20110305672A1 (en) * | 2008-07-25 | 2011-12-15 | University Of Georgia Research Foundation, Inc. | COMPOSITIONS FOR MESODERM DERIVED ISL1+ MULTIPOTENT CELLS (IMPs), EPICARDIAL PROGENITOR CELLS (EPCs) AND MULTIPOTENT CD56C CELLS (C56Cs) AND METHODS OF PRODUCING AND USING SAME |
| US20150329821A1 (en) * | 2012-10-19 | 2015-11-19 | Agency For Science, Technology And Research | Methods of differentiating stem cells into one or more cell lineages |
| US10787640B2 (en) * | 2015-03-03 | 2020-09-29 | The Board Of Trustees Of The Leland Stanford Junior University | Producing mesodermal cell types and methods of using the same |
-
2020
- 2020-08-25 CA CA3150015A patent/CA3150015A1/en active Pending
- 2020-08-25 WO PCT/US2020/047846 patent/WO2021041443A2/en not_active Ceased
- 2020-08-25 US US17/638,753 patent/US20220275341A1/en active Pending
- 2020-08-25 EP EP20857981.3A patent/EP4022036A4/en active Pending
- 2020-08-25 CN CN202080060072.9A patent/CN114430774A/zh active Pending
- 2020-08-25 JP JP2022512466A patent/JP7780423B2/ja active Active
- 2020-08-25 AU AU2020337417A patent/AU2020337417A1/en not_active Abandoned
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