JP2022545462A5 - - Google Patents
Info
- Publication number
- JP2022545462A5 JP2022545462A5 JP2022511127A JP2022511127A JP2022545462A5 JP 2022545462 A5 JP2022545462 A5 JP 2022545462A5 JP 2022511127 A JP2022511127 A JP 2022511127A JP 2022511127 A JP2022511127 A JP 2022511127A JP 2022545462 A5 JP2022545462 A5 JP 2022545462A5
- Authority
- JP
- Japan
- Prior art keywords
- targeting system
- dna targeting
- grna
- polynucleotide sequence
- pax7
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962888916P | 2019-08-19 | 2019-08-19 | |
| US62/888,916 | 2019-08-19 | ||
| US202062968743P | 2020-01-31 | 2020-01-31 | |
| US62/968,743 | 2020-01-31 | ||
| PCT/US2020/047080 WO2021034984A2 (en) | 2019-08-19 | 2020-08-19 | Skeletal myoblast progenitor cell lineage specification by crispr/cas9-based transcriptional activators |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022545462A JP2022545462A (ja) | 2022-10-27 |
| JP2022545462A5 true JP2022545462A5 (https=) | 2023-08-29 |
Family
ID=74660070
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022511127A Pending JP2022545462A (ja) | 2019-08-19 | 2020-08-19 | Ｃｒｉｓｐｒ／ｃａｓ９ベースの転写活性化因子による骨格筋芽細胞前駆細胞系譜特定 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20220305141A1 (https=) |
| EP (1) | EP4017544A4 (https=) |
| JP (1) | JP2022545462A (https=) |
| CN (1) | CN114599403A (https=) |
| CA (1) | CA3151816A1 (https=) |
| WO (1) | WO2021034984A2 (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013163628A2 (en) | 2012-04-27 | 2013-10-31 | Duke University | Genetic correction of mutated genes |
| US9828582B2 (en) | 2013-03-19 | 2017-11-28 | Duke University | Compositions and methods for the induction and tuning of gene expression |
| WO2016130600A2 (en) | 2015-02-09 | 2016-08-18 | Duke University | Compositions and methods for epigenome editing |
| WO2017035416A2 (en) | 2015-08-25 | 2017-03-02 | Duke University | Compositions and methods of improving specificity in genomic engineering using rna-guided endonucleases |
| EP4089175A1 (en) | 2015-10-13 | 2022-11-16 | Duke University | Genome engineering with type i crispr systems in eukaryotic cells |
| KR102787119B1 (ko) | 2015-11-30 | 2025-03-27 | 듀크 유니버시티 | 유전자 편집에 의한 인간 디스트로핀 유전자의 교정을 위한 치료용 표적 및 사용 방법 |
| US20190127713A1 (en) | 2016-04-13 | 2019-05-02 | Duke University | Crispr/cas9-based repressors for silencing gene targets in vivo and methods of use |
| JP7490211B2 (ja) | 2016-07-19 | 2024-05-27 | デューク ユニバーシティ | Ｃｐｆ１に基づくゲノム編集の治療適用 |
| EP3740580A4 (en) | 2018-01-19 | 2021-10-20 | Duke University | GENOME ENGINEERING WITH CRISPR-CAS SYSTEMS IN EUKARYONTS |
| IL317874A (en) | 2022-06-24 | 2025-02-01 | Tune Therapeutics Inc | Compounds, systems and methods for reducing low density lipoproteins through targeted gene suppression |
| WO2024092258A2 (en) * | 2022-10-27 | 2024-05-02 | Duke University | Direct reprogramming of human astrocytes to neurons with crispr-based transcriptional activation |
| CN116356003B (zh) * | 2023-05-12 | 2025-12-16 | 中山大学 | 一种高精度及高覆盖度的谱系树追踪方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040120933A9 (en) * | 2001-09-17 | 2004-06-24 | Rudnicki Michael A. | Pax-encoding vector and use thereof |
| CA2954791C (en) * | 2014-07-14 | 2025-11-18 | The Regents Of The University Of California | CRISPR/CAS TRANSCRIPTIONAL MODULATION |
| WO2016130600A2 (en) * | 2015-02-09 | 2016-08-18 | Duke University | Compositions and methods for epigenome editing |
| JP2018011546A (ja) * | 2016-07-20 | 2018-01-25 | 国立研究開発法人国立精神・神経医療研究センター | 骨格筋前駆細胞の製造方法 |
| JP2019103393A (ja) * | 2017-12-08 | 2019-06-27 | 京都府公立大学法人 | 骨格筋幹細胞誘導方法 |
-
2020
- 2020-08-19 JP JP2022511127A patent/JP2022545462A/ja active Pending
- 2020-08-19 US US17/636,754 patent/US20220305141A1/en active Pending
- 2020-08-19 CA CA3151816A patent/CA3151816A1/en active Pending
- 2020-08-19 CN CN202080058261.2A patent/CN114599403A/zh active Pending
- 2020-08-19 WO PCT/US2020/047080 patent/WO2021034984A2/en not_active Ceased
- 2020-08-19 EP EP20855079.8A patent/EP4017544A4/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2022545462A5 (https=) | ||
| US11155796B2 (en) | Compositions and methods for epigenome editing | |
| US10519454B2 (en) | Genome editing using Campylobacter jejuni CRISPR/CAS system-derived RGEN | |
| JP2025181841A5 (https=) | ||
| FI3988656T3 (fi) | Nukleosomien kanssa vuorovaikutteisten proteiinidomeenien käyttö tehostamaan kohdennettua genomimodifikaatiota | |
| FI3802807T3 (fi) | Rna-ohjattuja nukleaaseja ja niiden aktiivisia fragmentteja ja variantteja ja menetelmiä niiden käyttämiseksi | |
| FI4118198T3 (fi) | Rna-ohjattuja nukleaaseja ja niiden aktiivisia fragmentteja ja variantteja ja käyttömenetelmiä | |
| JP2022545385A5 (https=) | ||
| Arkhipova et al. | The steps of reverse transcription of Drosophila mobile dispersed genetic elements and U3-R-U5 structure of their LTRs | |
| CN111757889A (zh) | 新型CRISPR/Cas12f酶和系统 | |
| JP2022519507A5 (https=) | ||
| JP2024511163A5 (https=) | ||
| JP2017537611A5 (https=) | ||
| FI3310917T4 (fi) | Uusia crispr-entsyymejä ja -järjestelmiä | |
| CA3151816A1 (en) | Skeletal myoblast progenitor cell lineage specification by crispr/cas9-based transcriptional activators | |
| FI3250691T3 (fi) | Crispr hybridi dna/rna polynukleotidit ja käyttömenetelmät | |
| JP2012520085A5 (https=) | ||
| AR125191A1 (es) | Enzimas modificadoras del adn y sus fragmentos activos y variantes y métodos de uso | |
| Pečenková et al. | Bacteriophage B103: complete DNA sequence of its genome and relationship to other Bacillus phages | |
| US20250319203A1 (en) | Complex and use thereof | |
| RU2022105597A (ru) | Искусственно созданная система управления функцией шк | |
| JP2021518159A5 (https=) | ||
| JP2023529844A5 (https=) | ||
| JP2024522764A5 (https=) | ||
| JP2024518413A5 (https=) |