JP2022543203A5 - - Google Patents
Info
- Publication number
- JP2022543203A5 JP2022543203A5 JP2022505198A JP2022505198A JP2022543203A5 JP 2022543203 A5 JP2022543203 A5 JP 2022543203A5 JP 2022505198 A JP2022505198 A JP 2022505198A JP 2022505198 A JP2022505198 A JP 2022505198A JP 2022543203 A5 JP2022543203 A5 JP 2022543203A5
- Authority
- JP
- Japan
- Prior art keywords
- difluoromethoxy
- phenyl
- ethyl
- hydroxy
- trifluoromethoxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025112976A JP7897992B2 (ja) | 2019-08-02 | 2025-07-03 | Ｋｖ７カリウムチャネル開口薬としてのアルコール誘導体 |
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP19189750.3 | 2019-08-02 | ||
| EP19189750 | 2019-08-02 | ||
| CN201910734123.0 | 2019-08-09 | ||
| CN201910734123 | 2019-08-09 | ||
| EP19191887 | 2019-08-15 | ||
| EP19191887.9 | 2019-08-15 | ||
| PCT/EP2020/071520 WO2021023617A1 (en) | 2019-08-02 | 2020-07-30 | Alcohol derivatives as kv7 potassium channel openers |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025112976A Division JP7897992B2 (ja) | 2019-08-02 | 2025-07-03 | Ｋｖ７カリウムチャネル開口薬としてのアルコール誘導体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022543203A JP2022543203A (ja) | 2022-10-11 |
| JP2022543203A5 true JP2022543203A5 (enExample) | 2023-08-04 |
| JP7720829B2 JP7720829B2 (ja) | 2025-08-08 |
Family
ID=71894829
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022505198A Active JP7720829B2 (ja) | 2019-08-02 | 2020-07-30 | Ｋｖ７カリウムチャネル開口薬としてのアルコール誘導体 |
| JP2025112976A Active JP7897992B2 (ja) | 2019-08-02 | 2025-07-03 | Ｋｖ７カリウムチャネル開口薬としてのアルコール誘導体 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025112976A Active JP7897992B2 (ja) | 2019-08-02 | 2025-07-03 | Ｋｖ７カリウムチャネル開口薬としてのアルコール誘導体 |
Country Status (27)
| Country | Link |
|---|---|
| EP (2) | EP4461725A3 (enExample) |
| JP (2) | JP7720829B2 (enExample) |
| KR (1) | KR102957984B1 (enExample) |
| CN (1) | CN114206830B (enExample) |
| AU (1) | AU2020325517B2 (enExample) |
| BR (1) | BR112021006324A2 (enExample) |
| CA (1) | CA3148719A1 (enExample) |
| CL (1) | CL2022000221A1 (enExample) |
| CO (1) | CO2022000080A2 (enExample) |
| CR (1) | CR20220028A (enExample) |
| DO (1) | DOP2022000026A (enExample) |
| EC (1) | ECSP22008993A (enExample) |
| ES (1) | ES2989376T3 (enExample) |
| GE (2) | GEAP202415862A (enExample) |
| HR (1) | HRP20241444T1 (enExample) |
| HU (1) | HUE069310T2 (enExample) |
| IL (1) | IL290193B2 (enExample) |
| JO (1) | JOP20220017A1 (enExample) |
| MA (1) | MA56708B1 (enExample) |
| MX (1) | MX2022001063A (enExample) |
| PE (1) | PE20220345A1 (enExample) |
| PH (1) | PH12022550192A1 (enExample) |
| PL (1) | PL4007634T3 (enExample) |
| RS (1) | RS66130B1 (enExample) |
| SM (1) | SMT202400445T1 (enExample) |
| WO (1) | WO2021023617A1 (enExample) |
| ZA (1) | ZA202109598B (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2989376T3 (es) * | 2019-08-02 | 2024-11-26 | H Lundbeck As | Derivados de alcohol como abridores del canal de potasio Kv7 |
| AU2024310446A1 (en) * | 2023-06-27 | 2026-01-22 | Saniona A/S | Kv7 modulators |
| WO2026132415A1 (en) * | 2024-12-20 | 2026-06-25 | Saniona A/S | Kv7 modulators |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6893858B2 (en) | 2000-05-26 | 2005-05-17 | Bristol-Myers Squibb Company | Human kcnq5 potassium channel, methods and compositions thereof |
| WO2001096540A2 (en) | 2000-06-11 | 2001-12-20 | Dupont Pharmaceuticals Company | Hepatitis c protease exosite for inhibitor design |
| US7091202B2 (en) * | 2004-09-15 | 2006-08-15 | Bristol-Myers Squibb Company | 4-arylspirocycloalkyl-2-aminopyrimidine carboxamide KCNQ potassium channel modulators |
| US7790770B2 (en) * | 2005-11-23 | 2010-09-07 | Bristol-Myers Squibb Company | Heterocyclic CETP inhibitors |
| US20090118285A1 (en) | 2006-02-07 | 2009-05-07 | H. Lundbeck A/S | Use of kcnq-openers for treating or reducing the symptoms of schizophrenia |
| WO2007104717A1 (en) * | 2006-03-15 | 2007-09-20 | Neurosearch A/S | Quinazolinones and their use as potassium channels activators |
| CN101790374A (zh) | 2007-08-01 | 2010-07-28 | H.隆德贝克有限公司 | Kcnq钾通道开放剂用于减轻多巴胺能系统受到干扰的障碍或病症的症状或治疗这种障碍或病症的用途 |
| TW201024286A (en) * | 2008-11-27 | 2010-07-01 | Neurosearch As | Novel compounds |
| EP2928860A1 (en) * | 2012-12-10 | 2015-10-14 | H. Lundbeck A/S | New positive allosteric modulators of nicotinic acetylcholine receptor |
| WO2014145852A2 (en) * | 2013-03-15 | 2014-09-18 | Knopp Biosciences Llc | Imidazo(4,5-b) pyridin-2-yl amides as kv7 channel activators |
| ES2749103T3 (es) * | 2014-09-12 | 2020-03-19 | Knopp Biosciences Llc | Benzoimidazol-1,2-ilamidas como activadores del canal Kv7 |
| JP2017095366A (ja) | 2015-11-18 | 2017-06-01 | 持田製薬株式会社 | 新規ビアリールアミド誘導体 |
| CN105663136A (zh) * | 2016-01-15 | 2016-06-15 | 河北中医学院 | 法舒地尔作为制备选择性Kv7离子通道激活剂药物的应用 |
| US10590067B2 (en) * | 2018-02-20 | 2020-03-17 | H. Lundbeck A/S | Alcohol derivatives of carboxamides as Kv7 potassium channel openers |
| ES3032221T3 (en) * | 2018-02-20 | 2025-07-16 | H Lundbeck As | Alcohol derivatives as kv7 potassium channel openers |
| ES2989376T3 (es) * | 2019-08-02 | 2024-11-26 | H Lundbeck As | Derivados de alcohol como abridores del canal de potasio Kv7 |
| US12508239B2 (en) * | 2019-08-02 | 2025-12-30 | H. Lundbeck A/S | Alcohol derivatives as Kv7 potassium channel openers for use in epilepsy or seizures |
-
2020
- 2020-07-30 ES ES20749879T patent/ES2989376T3/es active Active
- 2020-07-30 HU HUE20749879A patent/HUE069310T2/hu unknown
- 2020-07-30 IL IL290193A patent/IL290193B2/en unknown
- 2020-07-30 RS RS20241162A patent/RS66130B1/sr unknown
- 2020-07-30 EP EP24203380.1A patent/EP4461725A3/en active Pending
- 2020-07-30 PE PE2022000184A patent/PE20220345A1/es unknown
- 2020-07-30 PL PL20749879.1T patent/PL4007634T3/pl unknown
- 2020-07-30 MX MX2022001063A patent/MX2022001063A/es unknown
- 2020-07-30 CA CA3148719A patent/CA3148719A1/en active Pending
- 2020-07-30 CR CR20220028A patent/CR20220028A/es unknown
- 2020-07-30 WO PCT/EP2020/071520 patent/WO2021023617A1/en not_active Ceased
- 2020-07-30 EP EP20749879.1A patent/EP4007634B1/en active Active
- 2020-07-30 GE GEAP202415862A patent/GEAP202415862A/en unknown
- 2020-07-30 SM SM20240445T patent/SMT202400445T1/it unknown
- 2020-07-30 KR KR1020227002204A patent/KR102957984B1/ko active Active
- 2020-07-30 BR BR112021006324A patent/BR112021006324A2/pt unknown
- 2020-07-30 CN CN202080051950.0A patent/CN114206830B/zh active Active
- 2020-07-30 MA MA56708A patent/MA56708B1/fr unknown
- 2020-07-30 PH PH1/2022/550192A patent/PH12022550192A1/en unknown
- 2020-07-30 HR HRP20241444TT patent/HRP20241444T1/hr unknown
- 2020-07-30 AU AU2020325517A patent/AU2020325517B2/en active Active
- 2020-07-30 GE GEAP202015862A patent/GEP20247629B/en unknown
- 2020-07-30 JP JP2022505198A patent/JP7720829B2/ja active Active
-
2021
- 2021-11-25 ZA ZA2021/09598A patent/ZA202109598B/en unknown
-
2022
- 2022-01-11 CO CONC2022/0000080A patent/CO2022000080A2/es unknown
- 2022-01-25 JO JOP/2022/0017A patent/JOP20220017A1/ar unknown
- 2022-01-27 CL CL2022000221A patent/CL2022000221A1/es unknown
- 2022-02-02 DO DO2022000026A patent/DOP2022000026A/es unknown
- 2022-02-04 EC ECSENADI20228993A patent/ECSP22008993A/es unknown
-
2025
- 2025-07-03 JP JP2025112976A patent/JP7897992B2/ja active Active
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