JP2022541514A5 - - Google Patents

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Publication number
JP2022541514A5
JP2022541514A5 JP2022502902A JP2022502902A JP2022541514A5 JP 2022541514 A5 JP2022541514 A5 JP 2022541514A5 JP 2022502902 A JP2022502902 A JP 2022502902A JP 2022502902 A JP2022502902 A JP 2022502902A JP 2022541514 A5 JP2022541514 A5 JP 2022541514A5
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JP
Japan
Prior art keywords
alkyl
pharmaceutically acceptable
solvate
acceptable salt
compound according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2022502902A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022541514A (ja
JP7595642B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/IB2020/000668 external-priority patent/WO2021009567A1/en
Publication of JP2022541514A publication Critical patent/JP2022541514A/ja
Publication of JP2022541514A5 publication Critical patent/JP2022541514A5/ja
Application granted granted Critical
Publication of JP7595642B2 publication Critical patent/JP7595642B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2022502902A 2019-07-17 2020-07-16 Nlrp3モジュレーター Active JP7595642B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962875409P 2019-07-17 2019-07-17
US62/875,409 2019-07-17
PCT/IB2020/000668 WO2021009567A1 (en) 2019-07-17 2020-07-16 Nlrp3 modulators

Publications (3)

Publication Number Publication Date
JP2022541514A JP2022541514A (ja) 2022-09-26
JP2022541514A5 true JP2022541514A5 (enExample) 2023-07-06
JP7595642B2 JP7595642B2 (ja) 2024-12-06

Family

ID=72659815

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022502902A Active JP7595642B2 (ja) 2019-07-17 2020-07-16 Nlrp3モジュレーター

Country Status (11)

Country Link
US (1) US12351564B2 (enExample)
EP (1) EP3999179A1 (enExample)
JP (1) JP7595642B2 (enExample)
KR (1) KR102852270B1 (enExample)
CN (1) CN114555569B (enExample)
AU (1) AU2020314186B2 (enExample)
BR (1) BR112022000855A2 (enExample)
CA (1) CA3147571A1 (enExample)
IL (1) IL289890B2 (enExample)
MX (1) MX2022000712A (enExample)
WO (1) WO2021009567A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2020312800B2 (en) 2019-07-17 2026-04-23 Zomagen Biosciences Ltd N-((1,2,3,5,6,7-hexahydro-s-indacen-4-yl)carbamoyl)-4,5,6,7-tetrahydrobenzofuran -2-sulfonamide derivatives and related compounds as NLPR3 modulators for the treatment of multiple sclerosis (ms)
JP7595642B2 (ja) 2019-07-17 2024-12-06 ズーマゲン バイオサイエンシーズ エルティーディー Nlrp3モジュレーター
KR20220154165A (ko) 2020-03-16 2022-11-21 조마젠 바이오사이언시즈 엘티디 Nlrp3 조절제
JP7825294B2 (ja) * 2021-02-10 2026-03-06 ハンジョウ イノゲート ファーマ カンパニー リミテッド Nlrp3阻害剤としての化合物
EP4362946A4 (en) * 2021-06-29 2025-05-21 Zomagen Biosciences Ltd Nlrp3 modulators
KR102877100B1 (ko) 2022-05-30 2025-10-24 주식회사 엘지에너지솔루션 배터리 진단 장치 및 방법
WO2025153532A1 (en) 2024-01-16 2025-07-24 NodThera Limited Nlrp3 inhibitors and glp-1 agonists combination therapies
WO2026054623A1 (ko) * 2024-09-09 2026-03-12 (주) 업테라 신규 nlrp3 억제제 화합물

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102727059B1 (ko) 2015-02-16 2024-11-05 더 유니버서티 어브 퀸슬랜드 설포닐우레아와 관련 화합물 및 그 용도
CN109071454B (zh) 2016-02-16 2023-02-17 昆士兰大学 磺酰脲和相关化合物及其用途
ES2940611T3 (es) 2016-04-18 2023-05-09 Novartis Ag Compuestos y composiciones para el tratamiento de afecciones asociadas a la actividad de NLRP
US11597706B2 (en) 2016-04-18 2023-03-07 Novartis Ag Compounds and compositions for treating conditions associated with NLRP activity
EP3272739A1 (en) 2016-07-20 2018-01-24 NodThera Limited Sulfonyl urea derivatives and their use in the control of interleukin-1 activity
CA3047336A1 (en) * 2017-01-23 2018-07-26 Jecure Therapeutics, Inc. Chemical compounds as inhibitors of interleukin-1 activity
AU2017416068A1 (en) 2017-05-24 2019-10-31 The Provost, Fellows, Foundation Scholars, And Other Members Of Board, Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth Near Dublin Novel compounds and uses
US11465992B2 (en) * 2017-07-07 2022-10-11 Inflazome Limited Sulfonamide carboxamide compounds
US11542255B2 (en) * 2017-08-15 2023-01-03 Inflazome Limited Sulfonylureas and sulfonylthioureas as NLRP3 inhibitors
MX2020001776A (es) * 2017-08-15 2020-03-24 Inflazome Ltd Sulfonilureas y sulfoniltioureas como inhibidores de nlrp3.
JP2020531448A (ja) * 2017-08-15 2020-11-05 インフレイゾーム リミテッド 新規なスルホンアミドカルボキサミド化合物
EP3697758B1 (en) * 2017-10-17 2022-07-06 Novartis AG Sulphonamides and compositions thereof for treating conditions associated with nlrp activity
GB201721185D0 (en) 2017-12-18 2018-01-31 Nodthera Ltd Sulphonyl urea derivatives
EP3823974A1 (en) 2018-07-20 2021-05-26 F. Hoffmann-La Roche AG Sulfonimidamide compounds as inhibitors of interleukin-1 activity
CN113056451A (zh) 2018-10-24 2021-06-29 诺华股份有限公司 用于治疗与nlrp活性相关的病症的化合物和组合物
JP7595642B2 (ja) 2019-07-17 2024-12-06 ズーマゲン バイオサイエンシーズ エルティーディー Nlrp3モジュレーター
AU2020312800B2 (en) 2019-07-17 2026-04-23 Zomagen Biosciences Ltd N-((1,2,3,5,6,7-hexahydro-s-indacen-4-yl)carbamoyl)-4,5,6,7-tetrahydrobenzofuran -2-sulfonamide derivatives and related compounds as NLPR3 modulators for the treatment of multiple sclerosis (ms)
CL2022002490A1 (es) 2020-03-16 2023-05-05 Novartis Ag Derivados de biarilo como inhibidores de la interacción proteína-proteína de yap/taz-tead
KR20220154165A (ko) 2020-03-16 2022-11-21 조마젠 바이오사이언시즈 엘티디 Nlrp3 조절제
UY39129A (es) 2020-03-16 2021-10-29 Novartis Ag Derivados de biarilo como inhibidores de la interacción proteína-proteína de yap/taz-tead

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