JP2022541273A5 - - Google Patents
Info
- Publication number
- JP2022541273A5 JP2022541273A5 JP2022503424A JP2022503424A JP2022541273A5 JP 2022541273 A5 JP2022541273 A5 JP 2022541273A5 JP 2022503424 A JP2022503424 A JP 2022503424A JP 2022503424 A JP2022503424 A JP 2022503424A JP 2022541273 A5 JP2022541273 A5 JP 2022541273A5
- Authority
- JP
- Japan
- Prior art keywords
- domain
- activity
- terminus
- seq
- fusion protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024189563A JP2025020231A (ja) | 2019-07-19 | 2024-10-29 | 最適化されたタンパク質リンカーおよび使用方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962876275P | 2019-07-19 | 2019-07-19 | |
| US62/876,275 | 2019-07-19 | ||
| PCT/US2020/042553 WO2021016086A1 (en) | 2019-07-19 | 2020-07-17 | Optimized protein linkers and methods of use |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024189563A Division JP2025020231A (ja) | 2019-07-19 | 2024-10-29 | 最適化されたタンパク質リンカーおよび使用方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022541273A JP2022541273A (ja) | 2022-09-22 |
| JP2022541273A5 true JP2022541273A5 (https=) | 2023-07-18 |
Family
ID=74194146
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022503424A Pending JP2022541273A (ja) | 2019-07-19 | 2020-07-17 | 最適化されたタンパク質リンカーおよび使用方法 |
| JP2024189563A Pending JP2025020231A (ja) | 2019-07-19 | 2024-10-29 | 最適化されたタンパク質リンカーおよび使用方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024189563A Pending JP2025020231A (ja) | 2019-07-19 | 2024-10-29 | 最適化されたタンパク質リンカーおよび使用方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US11072785B2 (https=) |
| EP (1) | EP3987021A4 (https=) |
| JP (2) | JP2022541273A (https=) |
| CN (2) | CN120591235A (https=) |
| AU (1) | AU2020316331B2 (https=) |
| CA (1) | CA3147253A1 (https=) |
| WO (1) | WO2021016086A1 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2015330699B2 (en) | 2014-10-10 | 2021-12-02 | Editas Medicine, Inc. | Compositions and methods for promoting homology directed repair |
| CA3147253A1 (en) * | 2019-07-19 | 2021-01-28 | Pairwise Plants Services, Inc. | Optimized protein linkers and methods of use |
| EP4185699A1 (en) | 2020-07-21 | 2023-05-31 | Pairwise Plants Services, Inc. | Optimized protein linkers and methods of use |
| US12123006B2 (en) * | 2021-05-18 | 2024-10-22 | Shanghaitech University | Base editing tool and use thereof |
| EP4399293A4 (en) * | 2021-09-10 | 2025-10-15 | Arbor Biotechnologies Inc | COMPOSITIONS COMPRISING A CAS12I POLYPEPTIDE AND USES THEREOF |
| WO2023164722A1 (en) * | 2022-02-28 | 2023-08-31 | Pairwise Plants Services, Inc. | Engineered crispr-cas effector proteins and methods of use thereof |
| CN116217741B (zh) * | 2023-02-27 | 2025-06-27 | 河北科技大学 | 一种高效率且低脱靶率的精确基因编辑方法 |
| US12428636B1 (en) | 2024-07-08 | 2025-09-30 | Pairwise Plants Services, Inc. | Methods and compositions for modification of protospacer adjacent motif specificity of CAS12A |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6747137B1 (en) * | 1998-02-13 | 2004-06-08 | Genome Therapeutics Corporation | Nucleic acid sequences relating to Candida albicans for diagnostics and therapeutics |
| US7214786B2 (en) * | 2000-12-14 | 2007-05-08 | Kovalic David K | Nucleic acid molecules and other molecules associated with plants and uses thereof for plant improvement |
| FR2862659B1 (fr) * | 2003-11-21 | 2006-02-10 | Pasteur Institut | Genome de legionella pneumophila souche paris- applications diagnostiques et epidemiologiques |
| WO2009009142A2 (en) * | 2007-07-10 | 2009-01-15 | Monsanto Technology, Llc | Transgenic plants with enhanced agronomic traits |
| US20110182862A1 (en) * | 2009-04-03 | 2011-07-28 | Green Wayne A | Endophytic fungus and uses therefor |
| WO2014020129A2 (en) | 2012-08-01 | 2014-02-06 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Allatostatin-b peptides for inducing the settlement of lophotrochozoan marine larvae |
| CN110214183A (zh) | 2016-08-03 | 2019-09-06 | 哈佛大学的校长及成员们 | 腺苷核碱基编辑器及其用途 |
| KR20230125856A (ko) * | 2016-12-23 | 2023-08-29 | 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 | Pcsk9의 유전자 편집 |
| US12390514B2 (en) * | 2017-03-09 | 2025-08-19 | President And Fellows Of Harvard College | Cancer vaccine |
| KR20240116572A (ko) * | 2017-03-23 | 2024-07-29 | 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 | 핵산 프로그램가능한 dna 결합 단백질을 포함하는 핵염기 편집제 |
| WO2018213726A1 (en) * | 2017-05-18 | 2018-11-22 | The Broad Institute, Inc. | Systems, methods, and compositions for targeted nucleic acid editing |
| CN108823202A (zh) * | 2017-06-15 | 2018-11-16 | 中山大学 | 用于特异性修复人hbb基因突变的碱基编辑系统、方法、试剂盒及其应用 |
| WO2019041296A1 (zh) * | 2017-09-01 | 2019-03-07 | 上海科技大学 | 一种碱基编辑系统及方法 |
| US11649442B2 (en) * | 2017-09-08 | 2023-05-16 | The Regents Of The University Of California | RNA-guided endonuclease fusion polypeptides and methods of use thereof |
| EP3727469A4 (en) * | 2017-12-22 | 2021-12-01 | The Broad Institute, Inc. | NEW CRISPR ENZYMES AND SYSTEMS |
| CN109957569B (zh) * | 2017-12-22 | 2022-10-25 | 苏州齐禾生科生物科技有限公司 | 基于cpf1蛋白的碱基编辑系统和方法 |
| CA3147253A1 (en) * | 2019-07-19 | 2021-01-28 | Pairwise Plants Services, Inc. | Optimized protein linkers and methods of use |
| EP4185699A1 (en) * | 2020-07-21 | 2023-05-31 | Pairwise Plants Services, Inc. | Optimized protein linkers and methods of use |
-
2020
- 2020-07-17 CA CA3147253A patent/CA3147253A1/en active Pending
- 2020-07-17 CN CN202510765287.5A patent/CN120591235A/zh active Pending
- 2020-07-17 AU AU2020316331A patent/AU2020316331B2/en active Active
- 2020-07-17 WO PCT/US2020/042553 patent/WO2021016086A1/en not_active Ceased
- 2020-07-17 US US16/932,294 patent/US11072785B2/en active Active
- 2020-07-17 JP JP2022503424A patent/JP2022541273A/ja active Pending
- 2020-07-17 CN CN202080064288.2A patent/CN114375335B/zh active Active
- 2020-07-17 EP EP20844071.9A patent/EP3987021A4/en active Pending
-
2021
- 2021-06-22 US US17/354,220 patent/US11708568B2/en active Active
-
2024
- 2024-10-29 JP JP2024189563A patent/JP2025020231A/ja active Pending
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