JP2023536408A5 - - Google Patents
Info
- Publication number
- JP2023536408A5 JP2023536408A5 JP2023504348A JP2023504348A JP2023536408A5 JP 2023536408 A5 JP2023536408 A5 JP 2023536408A5 JP 2023504348 A JP2023504348 A JP 2023504348A JP 2023504348 A JP2023504348 A JP 2023504348A JP 2023536408 A5 JP2023536408 A5 JP 2023536408A5
- Authority
- JP
- Japan
- Prior art keywords
- activity
- domain
- fusion protein
- deaminase domain
- nucleic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063054449P | 2020-07-21 | 2020-07-21 | |
| US63/054,449 | 2020-07-21 | ||
| PCT/US2021/042457 WO2022020407A1 (en) | 2020-07-21 | 2021-07-21 | Optimized protein linkers and methods of use |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023536408A JP2023536408A (ja) | 2023-08-25 |
| JP2023536408A5 true JP2023536408A5 (https=) | 2024-07-30 |
Family
ID=77564139
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023504348A Pending JP2023536408A (ja) | 2020-07-21 | 2021-07-21 | 最適化されたタンパク質リンカーおよび使用方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US11718838B2 (https=) |
| EP (1) | EP4185699A1 (https=) |
| JP (1) | JP2023536408A (https=) |
| CN (1) | CN116391034A (https=) |
| AU (1) | AU2021313163B2 (https=) |
| CA (1) | CA3189443A1 (https=) |
| WO (1) | WO2022020407A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3147253A1 (en) * | 2019-07-19 | 2021-01-28 | Pairwise Plants Services, Inc. | Optimized protein linkers and methods of use |
| JP2025511267A (ja) | 2022-03-30 | 2025-04-15 | ビーエーエスエフ アグリカルチュラル ソリューションズ シード ユーエス エルエルシー | 最適化塩基エディター |
| CN121399264A (zh) * | 2023-06-28 | 2026-01-23 | 绿耘基因有限公司 | 切口酶介导的植物dna碱基编辑 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6747137B1 (en) | 1998-02-13 | 2004-06-08 | Genome Therapeutics Corporation | Nucleic acid sequences relating to Candida albicans for diagnostics and therapeutics |
| US7214786B2 (en) | 2000-12-14 | 2007-05-08 | Kovalic David K | Nucleic acid molecules and other molecules associated with plants and uses thereof for plant improvement |
| FR2862659B1 (fr) | 2003-11-21 | 2006-02-10 | Pasteur Institut | Genome de legionella pneumophila souche paris- applications diagnostiques et epidemiologiques |
| WO2009009142A2 (en) | 2007-07-10 | 2009-01-15 | Monsanto Technology, Llc | Transgenic plants with enhanced agronomic traits |
| US20110182862A1 (en) | 2009-04-03 | 2011-07-28 | Green Wayne A | Endophytic fungus and uses therefor |
| WO2014020129A2 (en) | 2012-08-01 | 2014-02-06 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Allatostatin-b peptides for inducing the settlement of lophotrochozoan marine larvae |
| US9790490B2 (en) | 2015-06-18 | 2017-10-17 | The Broad Institute Inc. | CRISPR enzymes and systems |
| CN110214183A (zh) | 2016-08-03 | 2019-09-06 | 哈佛大学的校长及成员们 | 腺苷核碱基编辑器及其用途 |
| KR20230125856A (ko) * | 2016-12-23 | 2023-08-29 | 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 | Pcsk9의 유전자 편집 |
| US12390514B2 (en) | 2017-03-09 | 2025-08-19 | President And Fellows Of Harvard College | Cancer vaccine |
| KR20240116572A (ko) | 2017-03-23 | 2024-07-29 | 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 | 핵산 프로그램가능한 dna 결합 단백질을 포함하는 핵염기 편집제 |
| US11649442B2 (en) | 2017-09-08 | 2023-05-16 | The Regents Of The University Of California | RNA-guided endonuclease fusion polypeptides and methods of use thereof |
| EP3727469A4 (en) * | 2017-12-22 | 2021-12-01 | The Broad Institute, Inc. | NEW CRISPR ENZYMES AND SYSTEMS |
| CN109957569B (zh) * | 2017-12-22 | 2022-10-25 | 苏州齐禾生科生物科技有限公司 | 基于cpf1蛋白的碱基编辑系统和方法 |
| CA3147253A1 (en) | 2019-07-19 | 2021-01-28 | Pairwise Plants Services, Inc. | Optimized protein linkers and methods of use |
-
2021
- 2021-07-21 EP EP21763165.4A patent/EP4185699A1/en active Pending
- 2021-07-21 WO PCT/US2021/042457 patent/WO2022020407A1/en not_active Ceased
- 2021-07-21 AU AU2021313163A patent/AU2021313163B2/en active Active
- 2021-07-21 CN CN202180061805.5A patent/CN116391034A/zh active Pending
- 2021-07-21 CA CA3189443A patent/CA3189443A1/en active Pending
- 2021-07-21 US US17/381,465 patent/US11718838B2/en active Active
- 2021-07-21 JP JP2023504348A patent/JP2023536408A/ja active Pending
-
2023
- 2023-06-14 US US18/334,407 patent/US12110517B2/en active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US20240336905A1 (en) | Class ii, type v crispr systems | |
| JP2022541273A5 (https=) | ||
| JP6454243B2 (ja) | 閉鎖型直鎖状ｄｎａの製造 | |
| JP6690005B2 (ja) | ナノポアシーケンシングのためのポリメラーゼ−鋳型複合体 | |
| KR102254602B1 (ko) | Cas9 변이체 및 그의 용도 | |
| JP2023536408A5 (https=) | ||
| KR101822902B1 (ko) | 뉴클레아제-매개 dna 조립 | |
| JP2022552409A5 (https=) | ||
| CA3236512A1 (en) | Compositions and methods for treating hemoglobinopathies | |
| WO2022056324A1 (en) | Base editing enzymes | |
| CN111615557B (zh) | 稳定且副作用少的基因组编辑用复合物和编码该复合物的核酸 | |
| KR20180074610A (ko) | 동물 배아의 염기 교정용 조성물 및 염기 교정 방법 | |
| JP2021528968A (ja) | 融合一本鎖ＤＮＡポリメラーゼＢｓｔ、融合ＤＮＡポリメラーゼＮｅｑＳＳＢ−Ｂｓｔをコードする核酸分子、その調製方法およびその利用 | |
| US20230348877A1 (en) | Base editing enzymes | |
| US20230193293A1 (en) | Linear covalently closed vectors and related compositions and methods thereof | |
| US20240352433A1 (en) | Enzymes with hepn domains | |
| JP4465741B2 (ja) | 二本鎖ｄｎａ断片の末端での連結 | |
| KR20170020091A (ko) | shRNA 발현 카세트의 제조방법, 그 방법에 의해 제조된 shRNA 발현 카세트 및 이를 포함하는 라이브러리 | |
| JP2025502107A5 (https=) | ||
| WO2023039377A1 (en) | Class ii, type v crispr systems | |
| KR100689795B1 (ko) | 복합체 형성 방법 | |
| NZ787124A (en) | Variants of cas12a nucleases and methods of making and use thereof | |
| Park et al. | Group II Intron-Like Reverse transcriptases function in double-strand break repair by microhomology-mediated end joining | |
| Liu et al. | Chlamydia pneumoniae AP endonuclease IV could cleave AP sites of double-and single-stranded DNA | |
| Liu et al. | The mechanism of base excision repair in Chlamydiophila pneumoniae |