JP2025502107A5 - - Google Patents
Info
- Publication number
- JP2025502107A5 JP2025502107A5 JP2024541082A JP2024541082A JP2025502107A5 JP 2025502107 A5 JP2025502107 A5 JP 2025502107A5 JP 2024541082 A JP2024541082 A JP 2024541082A JP 2024541082 A JP2024541082 A JP 2024541082A JP 2025502107 A5 JP2025502107 A5 JP 2025502107A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- mutant
- cas12a
- seq
- mutation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202263297182P | 2022-01-06 | 2022-01-06 | |
| US202263297189P | 2022-01-06 | 2022-01-06 | |
| US63/297,182 | 2022-01-06 | ||
| US63/297,189 | 2022-01-06 | ||
| PCT/IB2023/000043 WO2023131870A2 (en) | 2022-01-06 | 2023-01-06 | Endonuclease variants and methods of use |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2025502107A JP2025502107A (ja) | 2025-01-24 |
| JP2025502107A5 true JP2025502107A5 (https=) | 2026-01-14 |
Family
ID=85706783
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024541082A Pending JP2025502107A (ja) | 2022-01-06 | 2023-01-06 | Ｃａｓ１２ａエンドヌクレアーゼ変異体および使用方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20250388886A1 (https=) |
| EP (1) | EP4460566A2 (https=) |
| JP (1) | JP2025502107A (https=) |
| KR (1) | KR20240145468A (https=) |
| CN (1) | CN118742641A (https=) |
| AU (1) | AU2023205461A1 (https=) |
| CA (1) | CA3245296A1 (https=) |
| IL (1) | IL314074A (https=) |
| MX (1) | MX2024008362A (https=) |
| WO (1) | WO2023131870A2 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN118979028B (zh) * | 2024-09-20 | 2025-07-29 | 湖北洪山实验室 | 核酸内切酶Gs12-7MAX变体及其介导的基因编辑系统 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111801345A (zh) | 2017-07-28 | 2020-10-20 | 哈佛大学的校长及成员们 | 使用噬菌体辅助连续进化(pace)的进化碱基编辑器的方法和组合物 |
| MX2022004549A (es) * | 2019-10-17 | 2022-07-21 | Pairwise Plants Services Inc | Variantes de nucleasas cas12a, metodos de fabricacion y uso de las mismas. |
| CN116096878A (zh) * | 2020-05-01 | 2023-05-09 | 合成Dna技术公司 | 在非经典tttt前间区序列邻近基序处具有增强的切割活性的毛螺菌科菌种cas12a突变体 |
-
2023
- 2023-01-06 JP JP2024541082A patent/JP2025502107A/ja active Pending
- 2023-01-06 CA CA3245296A patent/CA3245296A1/en active Pending
- 2023-01-06 MX MX2024008362A patent/MX2024008362A/es unknown
- 2023-01-06 KR KR1020247026266A patent/KR20240145468A/ko active Pending
- 2023-01-06 US US18/726,872 patent/US20250388886A1/en active Pending
- 2023-01-06 IL IL314074A patent/IL314074A/en unknown
- 2023-01-06 AU AU2023205461A patent/AU2023205461A1/en active Pending
- 2023-01-06 CN CN202380023337.1A patent/CN118742641A/zh active Pending
- 2023-01-06 WO PCT/IB2023/000043 patent/WO2023131870A2/en not_active Ceased
- 2023-01-06 EP EP23712320.3A patent/EP4460566A2/en active Pending
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