JP2022540913A5 - - Google Patents

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Publication number
JP2022540913A5
JP2022540913A5 JP2022502530A JP2022502530A JP2022540913A5 JP 2022540913 A5 JP2022540913 A5 JP 2022540913A5 JP 2022502530 A JP2022502530 A JP 2022502530A JP 2022502530 A JP2022502530 A JP 2022502530A JP 2022540913 A5 JP2022540913 A5 JP 2022540913A5
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JP
Japan
Prior art keywords
nmdar
protein
construct
protein construct
ecd
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JP2022502530A
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English (en)
Japanese (ja)
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JP7659905B2 (ja
JP2022540913A (ja
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Priority claimed from PCT/EP2020/068732 external-priority patent/WO2021008890A1/en
Publication of JP2022540913A publication Critical patent/JP2022540913A/ja
Publication of JP2022540913A5 publication Critical patent/JP2022540913A5/ja
Priority to JP2025049513A priority Critical patent/JP2025094198A/ja
Application granted granted Critical
Publication of JP7659905B2 publication Critical patent/JP7659905B2/ja
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JP2022502530A 2019-07-16 2020-07-02 Ｎｍｄａｒ自己抗体を検出及び単離するためのｎｍｄａ受容体コンストラクト Active JP7659905B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025049513A JP2025094198A (ja) 2019-07-16 2025-03-25 Ｎｍｄａｒ自己抗体を検出及び単離するためのｎｍｄａ受容体コンストラクト

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP19186524.5 2019-07-16
EP19186524 2019-07-16
LU101308 2019-07-18
LULU101308 2019-07-18
PCT/EP2020/068732 WO2021008890A1 (en) 2019-07-16 2020-07-02 Nmda receptor constructs to detect and isolate nmdar autoantibodies

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025049513A Division JP2025094198A (ja) 2019-07-16 2025-03-25 Ｎｍｄａｒ自己抗体を検出及び単離するためのｎｍｄａ受容体コンストラクト

Publications (3)

Publication Number Publication Date
JP2022540913A JP2022540913A (ja) 2022-09-20
JP2022540913A5 true JP2022540913A5 (https=) 2023-06-27
JP7659905B2 JP7659905B2 (ja) 2025-04-10

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ID=71143759

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2022502530A Active JP7659905B2 (ja) 2019-07-16 2020-07-02 Ｎｍｄａｒ自己抗体を検出及び単離するためのｎｍｄａ受容体コンストラクト
JP2025049513A Pending JP2025094198A (ja) 2019-07-16 2025-03-25 Ｎｍｄａｒ自己抗体を検出及び単離するためのｎｍｄａ受容体コンストラクト

Family Applications After (1)

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JP2025049513A Pending JP2025094198A (ja) 2019-07-16 2025-03-25 Ｎｍｄａｒ自己抗体を検出及び単離するためのｎｍｄａ受容体コンストラクト

Country Status (6)

Country Link
US (1) US20230280340A1 (https=)
EP (1) EP3999850A1 (https=)
JP (2) JP7659905B2 (https=)
CN (1) CN114144427A (https=)
CA (1) CA3144900A1 (https=)
WO (1) WO2021008890A1 (https=)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3999850A1 (en) * 2019-07-16 2022-05-25 Deutsches Zentrum für Neurodegenerative Erkrankungen e.V. (DZNE) Nmda receptor constructs to detect and isolate nmdar autoantibodies
WO2021241616A1 (ja) 2020-05-27 2021-12-02 アステラス製薬株式会社 抗ヒトｎｒ１抗体誘導体
CN114957446B (zh) * 2022-05-31 2023-09-15 陕西脉元生物科技有限公司 与nmdar脑炎患者中的自身抗体结合的nmdar突变体及其构建方法
CN114891091B (zh) * 2022-06-13 2024-04-26 四川携光生物技术有限公司 一种抗nmdar脑炎重组抗原及应用
JPWO2024075803A1 (https=) * 2022-10-06 2024-04-11
CN116253790A (zh) * 2022-12-13 2023-06-13 迪亚莱博（张家港）生物科技有限公司 一种用于抗nmdar抗体检测的nmdar重组蛋白及其制备方法及其应用
CN116440950B (zh) * 2023-02-24 2023-09-12 华东理工大学 一种催化剂及其制备方法和应用
AU2024242885A1 (en) * 2023-03-30 2025-09-11 Arialys Therapeutics, Inc. Detection of autoantibodies against nr1
AU2024315618A1 (en) * 2023-08-01 2026-01-22 Merida Biosciences, Inc. Molecules for controlling autoimmune response
CN118566499B (zh) * 2024-08-02 2024-10-08 成都海默云因医学检验实验室有限公司 一种GluN1和GluN2B亚基融合表达检测抗NMDAR抗体的CBA方法及检测试剂
CN118937669B (zh) * 2024-10-11 2025-02-18 杭州臻源生物医药科技有限公司 双色荧光检测抗nmdar抗体用固定试剂、方法及应用
CN120721960B (zh) * 2025-08-19 2025-11-21 上海金域医学检验所有限公司 一种自身免疫性脑炎抗体检测指示试剂、试剂盒与制备工艺

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6770460B1 (en) * 1998-01-29 2004-08-03 Wallac Oy Fusion protein and its use in an immunoassay for the simultaneous detection of autoantibodies related to insulin-dependent diabetes mellitus
DE19818790A1 (de) 1998-04-27 1999-10-28 Affina Immuntechnik Gmbh Immunadsorptionsmatrix, Verfahren zu ihrer Herstellung und ihre Verwendung
AU2002220577A1 (en) 2000-09-28 2002-04-08 Affina Immuntechnik Gmbh Circulatory device for separating substances in bodily fluids, especially blood,and the use of said device
US6896872B2 (en) * 2001-06-27 2005-05-24 Svetlana A. Dambinova Rapid multiple panel of biomarkers in laboratory blood tests for TIA/stroke
EP2035452B1 (en) * 2006-06-22 2012-04-25 Novo Nordisk A/S Soluble heterodimeric receptors and uses thereof
ES2443490T3 (es) * 2006-08-15 2014-02-19 The Trustees Of The University Of Pennsylvania Métodos y composiciones para el diagnóstico y tratamiento de la encefalitis autoinmune o la epilepsia
DE102010053432A1 (de) * 2010-12-06 2012-06-06 Euroimmun Medizinische Labordiagnostika Ag Verfahren zum Nachweis von anti-NMDA-Rezeptor Autoantikörpern zum Einsatz in Diagnoseverfahren
WO2013041029A1 (en) * 2011-09-23 2013-03-28 Igenimed Pharmaceuticals Inc. Novel soluble ctla4 variants
KR20160135749A (ko) * 2014-03-18 2016-11-28 샌포드 헬스 유방암 검출용 시약 및 검출 방법
GB201409234D0 (en) * 2014-05-23 2014-07-09 Isis Innovation Method
EP3999850A1 (en) * 2019-07-16 2022-05-25 Deutsches Zentrum für Neurodegenerative Erkrankungen e.V. (DZNE) Nmda receptor constructs to detect and isolate nmdar autoantibodies

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