JP2022535798A - ハイパースペクトル定量的イメージング・サイトメトリ・システム - Google Patents

ハイパースペクトル定量的イメージング・サイトメトリ・システム Download PDF

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JP2022535798A
JP2022535798A JP2021571457A JP2021571457A JP2022535798A JP 2022535798 A JP2022535798 A JP 2022535798A JP 2021571457 A JP2021571457 A JP 2021571457A JP 2021571457 A JP2021571457 A JP 2021571457A JP 2022535798 A JP2022535798 A JP 2022535798A
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sample
radiation
wavelength
hyperspectral
encoded
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JP2022535798A5 (https=
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ホセ、マリオ、テネラ、モルガド
アルバロ、ロドリゲス、デ、ラ、ガラ
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Cytognos SL
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Cytognos SL
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1429—Signal processing
    • G01N15/1433—Signal processing using image recognition
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1434—Optical arrangements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/12—Generating the spectrum; Monochromators
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/12—Generating the spectrum; Monochromators
    • G01J3/26—Generating the spectrum; Monochromators using multiple reflection, e.g. Fabry-Perot interferometer, variable interference filters
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/28—Investigating the spectrum
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/28—Investigating the spectrum
    • G01J3/2823—Imaging spectrometer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/28—Investigating the spectrum
    • G01J3/30—Measuring the intensity of spectral lines directly on the spectrum itself
    • G01J3/32—Investigating bands of a spectrum in sequence by a single detector
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1429—Signal processing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/02—Details
    • G01J3/10—Arrangements of light sources specially adapted for spectrometry or colorimetry
    • G01J2003/102—Plural sources
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/12—Generating the spectrum; Monochromators
    • G01J2003/1226—Interference filters
    • G01J2003/123—Indexed discrete filters
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/12—Generating the spectrum; Monochromators
    • G01J2003/1226—Interference filters
    • G01J2003/1234—Continuously variable IF [CVIF]; Wedge type
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/12—Generating the spectrum; Monochromators
    • G01J2003/1226—Interference filters
    • G01J2003/1243—Pivoting IF or other position variation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/28—Investigating the spectrum
    • G01J3/2823—Imaging spectrometer
    • G01J2003/2826—Multispectral imaging, e.g. filter imaging
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N2015/1006—Investigating individual particles for cytology
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1434—Optical arrangements
    • G01N2015/144—Imaging characterised by its optical setup

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  • Physics & Mathematics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Chemical & Material Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Signal Processing (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
JP2021571457A 2019-05-31 2020-05-29 ハイパースペクトル定量的イメージング・サイトメトリ・システム Pending JP2022535798A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP19382444 2019-05-31
EP19382444.8 2019-05-31
PCT/EP2020/064984 WO2020239981A1 (en) 2019-05-31 2020-05-29 Hyperspectral quantitative imaging cytometry system

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JP2022535798A true JP2022535798A (ja) 2022-08-10
JP2022535798A5 JP2022535798A5 (https=) 2024-10-07

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US (1) US12078585B2 (https=)
EP (1) EP3977091B1 (https=)
JP (1) JP2022535798A (https=)
CN (2) CN120084706A (https=)
AU (1) AU2020281945B2 (https=)
CA (1) CA3142188A1 (https=)
WO (1) WO2020239981A1 (https=)

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US12493965B2 (en) * 2020-12-11 2025-12-09 Enumera Molecular, Inc. Methods and systems for image processing
US20230221178A1 (en) * 2022-01-11 2023-07-13 Modulight Corporation Apparatus and a method for fluorescence imaging
CN116309497B (zh) * 2023-03-26 2023-10-03 湖南医药学院 基于图像识别的癌细胞计数及预后预测的辅助分析方法

Citations (6)

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JP2001099710A (ja) * 1999-09-28 2001-04-13 Fuji Photo Film Co Ltd マルチバンド画像の分光反射率のスペクトル推定方法およびスペクトル推定システム
JP2006526783A (ja) * 2003-05-30 2006-11-24 アンドリュー エム． ラビノビッチ、 色分解および組織試料内の対象となる領域の検出
JP2009244270A (ja) * 2001-02-23 2009-10-22 Life Technologies Corp 検体分析において拡張ダイナミックレンジを提供する方法
JP2011127933A (ja) * 2009-12-15 2011-06-30 Olympus Corp 光制御装置、制御装置、光学スコープ及び光走査型光学装置
JP2012508366A (ja) * 2008-11-04 2012-04-05 ウィリアム・マーシュ・ライス・ユニバーシティ 画像マッピング分光計
JP2019504325A (ja) * 2016-02-02 2019-02-14 ケーエルエー−テンカー コーポレイション ハイパースペクトルイメージング計量システム及び方法

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US7554659B2 (en) * 2004-06-30 2009-06-30 Chemimage Corporation Hyperspectral visible absorption imaging of molecular probes and dyes in biomaterials
EP2024893B1 (en) 2006-05-12 2015-03-04 Janssen Diagnostics, LLC A laser illumination system in fluorescent microscopy
US10180398B2 (en) 2012-02-29 2019-01-15 National Technology & Engineering Solutions Of Sandia, Llc Trajectory-based triggering system for hyperspectral imaging flow cytometer
US9797836B1 (en) * 2012-02-29 2017-10-24 National Technology & Engineering Solutions Of Sandia, Llc Hyperspectral imaging flow cytometer
US20150297142A1 (en) * 2012-07-30 2015-10-22 Koninklijke Philips N.V. Device and method for extracting physiological information
US9494567B2 (en) * 2012-12-31 2016-11-15 Omni Medsci, Inc. Near-infrared lasers for non-invasive monitoring of glucose, ketones, HBA1C, and other blood constituents
US9733124B2 (en) * 2013-04-18 2017-08-15 BMG LABTECH, GmbH Microplate reader with linear variable filter
CN104516085B (zh) * 2013-09-30 2017-04-26 香港纺织及成衣研发中心有限公司 一种用于多光谱成像的快速调焦方法及装置
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WO2020239981A1 (en) 2020-12-03
AU2020281945A1 (en) 2021-12-16
US12078585B2 (en) 2024-09-03
CN120084706A (zh) 2025-06-03
CA3142188A1 (en) 2020-12-03
CN113906284A (zh) 2022-01-07
US20220228968A1 (en) 2022-07-21
AU2020281945B2 (en) 2025-06-05
EP3977091A1 (en) 2022-04-06
EP3977091B1 (en) 2025-12-31

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