JP2022534135A5 - - Google Patents
Info
- Publication number
- JP2022534135A5 JP2022534135A5 JP2022516254A JP2022516254A JP2022534135A5 JP 2022534135 A5 JP2022534135 A5 JP 2022534135A5 JP 2022516254 A JP2022516254 A JP 2022516254A JP 2022516254 A JP2022516254 A JP 2022516254A JP 2022534135 A5 JP2022534135 A5 JP 2022534135A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- acid sequence
- variable region
- seq
- chain variable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910419089 | 2019-05-20 | ||
| CN201910419089.8 | 2019-05-20 | ||
| PCT/CN2020/091235 WO2020233589A1 (zh) | 2019-05-20 | 2020-05-20 | 靶向cd19的全人源抗体及其应用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022534135A JP2022534135A (ja) | 2022-07-27 |
| JP2022534135A5 true JP2022534135A5 (https=) | 2023-03-17 |
| JP7566352B2 JP7566352B2 (ja) | 2024-10-15 |
Family
ID=73458076
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022516254A Active JP7566352B2 (ja) | 2019-05-20 | 2020-05-20 | Ｃｄ１９を標的とする完全ヒト抗体およびその応用 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US12516117B2 (https=) |
| EP (1) | EP3974452A4 (https=) |
| JP (1) | JP7566352B2 (https=) |
| CN (2) | CN113840841B (https=) |
| AU (1) | AU2020277525A1 (https=) |
| WO (1) | WO2020233589A1 (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3120563A1 (en) | 2018-11-26 | 2020-06-04 | Nkarta, Inc. | Methods for the simultaneous expansion of multiple immune cell types, related compositions and uses of same in cancer immunotherapy |
| EP3773918A4 (en) | 2019-03-05 | 2022-01-05 | Nkarta, Inc. | CD19 DIRECTED CHIMERIC ANTIGEN RECEPTORS AND THEIR USES IN IMMUNOTHERAPY |
| AU2021298707A1 (en) * | 2020-06-30 | 2023-02-23 | Nanjing IASO Biotechnology Co., Ltd. | Fully humanized bispecific chimeric antigen receptor targeting CD19 and CD22 and use thereof |
| WO2022257984A1 (zh) * | 2021-06-08 | 2022-12-15 | 南京驯鹿医疗技术有限公司 | 一种增强型嵌合抗原受体(car)细胞的制备及其应用 |
| CN114891108B (zh) * | 2022-05-30 | 2022-11-15 | 上海驯鹿生物技术有限公司 | 一种靶向bcma的全人源抗体及其应用 |
| CN115109140B (zh) * | 2022-06-20 | 2026-04-28 | 浙江大学医学院附属第一医院 | 一种靶向特异肿瘤细胞的t细胞受体库构建方法 |
| CN121127253A (zh) | 2023-02-28 | 2025-12-12 | 朱诺治疗学股份有限公司 | 治疗系统性自身免疫性疾病的细胞疗法 |
| EP4687962A1 (en) * | 2023-03-30 | 2026-02-11 | Cabaletta Bio, Inc. | Methods and compositions for treating autoimmune diseases |
| WO2025147545A1 (en) | 2024-01-03 | 2025-07-10 | Juno Therapeutics, Inc. | Lipid nanoparticles for delivery of nucleic acids and related methods and uses |
| WO2026020055A2 (en) | 2024-07-18 | 2026-01-22 | Juno Therapeutics, Inc. | Methods for assessing exosomes in a cell composition and related uses |
| WO2026050426A2 (en) | 2024-08-28 | 2026-03-05 | Juno Therapeutics, Inc. | Cd19-directed chimeric antigen receptor cell therapy for treating autoimmune and neurological diseases |
| CN119371540B (zh) * | 2024-12-10 | 2025-07-25 | 星实(上海)生物医药科技有限公司 | 抗cd19抗体及其应用 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2611814A1 (en) * | 2005-06-20 | 2007-01-04 | Medarex, Inc. | Cd19 antibodies and their uses |
| CN101233156B (zh) | 2005-06-20 | 2012-06-27 | 米德列斯公司 | Cd19抗体及其用途 |
| CL2007003622A1 (es) * | 2006-12-13 | 2009-08-07 | Medarex Inc | Anticuerpo monoclonal humano anti-cd19; composicion que lo comprende; y metodo de inhibicion del crecimiento de celulas tumorales. |
| CN104558181A (zh) | 2014-12-31 | 2015-04-29 | 四川大学 | 靶向b淋巴瘤细胞的人源单链抗体 |
| CN106554414B (zh) * | 2015-09-18 | 2019-04-23 | 上海科济制药有限公司 | 抗cd19全人抗体以及靶向cd19的免疫效应细胞 |
| MY196631A (en) | 2015-10-13 | 2023-04-24 | Eureka Therapeutics Inc | Antibody Agents Specific for Human Cd19 and uses Thereof |
| CN107880128B (zh) * | 2017-12-21 | 2021-03-02 | 常州费洛斯药业科技有限公司 | 一种抗cd19的全人源抗体或抗体片段及其方法和应用 |
| CN109293774B (zh) | 2018-10-16 | 2021-05-28 | 南京医科大学 | 特异性结合cd19的全人源化抗体及应用 |
| AU2021298707A1 (en) | 2020-06-30 | 2023-02-23 | Nanjing IASO Biotechnology Co., Ltd. | Fully humanized bispecific chimeric antigen receptor targeting CD19 and CD22 and use thereof |
| WO2022257984A1 (zh) | 2021-06-08 | 2022-12-15 | 南京驯鹿医疗技术有限公司 | 一种增强型嵌合抗原受体(car)细胞的制备及其应用 |
-
2020
- 2020-05-20 WO PCT/CN2020/091235 patent/WO2020233589A1/zh not_active Ceased
- 2020-05-20 EP EP20809306.2A patent/EP3974452A4/en active Pending
- 2020-05-20 US US17/613,367 patent/US12516117B2/en active Active
- 2020-05-20 JP JP2022516254A patent/JP7566352B2/ja active Active
- 2020-05-20 CN CN202080037449.9A patent/CN113840841B/zh active Active
- 2020-05-20 CN CN202310120560.XA patent/CN116589579A/zh active Pending
- 2020-05-20 AU AU2020277525A patent/AU2020277525A1/en active Pending
-
2025
- 2025-12-12 US US19/418,243 patent/US20260103517A1/en active Pending
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