JP2022534118A - 泌尿器系がんを治療する方法 - Google Patents

泌尿器系がんを治療する方法 Download PDF

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JP2022534118A
JP2022534118A JP2021570824A JP2021570824A JP2022534118A JP 2022534118 A JP2022534118 A JP 2022534118A JP 2021570824 A JP2021570824 A JP 2021570824A JP 2021570824 A JP2021570824 A JP 2021570824A JP 2022534118 A JP2022534118 A JP 2022534118A
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infigratinib
patient
fgfr3
pharmaceutically acceptable
acceptable salt
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JP2022534118A5 (https=
JPWO2020243442A5 (https=
Inventor
パニクッチ,リカルド
アランジョ,スーザン
ベルマン,クレイグ
モンティス,マイケル
ソイファー,ハリス
リー,ガング
ダブコウスキ,カール
マルリーニー,ダニエル
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QED Therapeutics Inc
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QED Therapeutics Inc
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Publication of JPWO2020243442A5 publication Critical patent/JPWO2020243442A5/ja
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    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
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    • A61K31/7068Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
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JP2021570824A 2019-05-31 2020-05-29 泌尿器系がんを治療する方法 Pending JP2022534118A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962855277P 2019-05-31 2019-05-31
US62/855,277 2019-05-31
US201962906194P 2019-09-26 2019-09-26
US62/906,194 2019-09-26
PCT/US2020/035140 WO2020243442A1 (en) 2019-05-31 2020-05-29 Methods of treating urinary system cancers

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JP2022534118A true JP2022534118A (ja) 2022-07-27
JP2022534118A5 JP2022534118A5 (https=) 2023-05-19
JPWO2020243442A5 JPWO2020243442A5 (https=) 2023-05-19

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US (1) US20220233537A1 (https=)
EP (1) EP3976833A4 (https=)
JP (1) JP2022534118A (https=)
KR (1) KR20220088830A (https=)
CN (1) CN114207151A (https=)
AU (1) AU2020282816A1 (https=)
CA (1) CA3141871A1 (https=)
IL (1) IL288408A (https=)
MX (1) MX2021014524A (https=)
PH (1) PH12021552973A1 (https=)
SG (1) SG11202112932QA (https=)
WO (1) WO2020243442A1 (https=)

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Publication number Priority date Publication date Assignee Title
CA3202267A1 (en) * 2020-12-18 2022-06-23 Riccardo Panicucci Methods of treating achondroplasia
CN117982507A (zh) * 2022-11-01 2024-05-07 Qed医药股份有限公司 英菲格拉替尼在治疗胃癌和腺癌中的用途
CN115785001B (zh) * 2022-11-23 2023-09-15 斯坦德药典标准物质研发(湖北)有限公司 一种英菲格拉替尼的制备方法
CN117558346B (zh) * 2023-09-01 2024-12-03 上海仁东医学检验所有限公司 Utuc分子分型及预后预测模型构建方法

Citations (4)

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JP2009523410A (ja) * 2005-12-08 2009-06-25 ノバルティス アクチエンゲゼルシャフト 遺伝子転写に対するfgfr3の阻害剤の効果
JP2017511792A (ja) * 2013-12-18 2017-04-27 イムクローン リミテッド ライアビリティ カンパニー 繊維芽細胞増殖因子受容体3(fgfr3)に対する化合物および治療的使用
WO2018145120A1 (en) * 2017-02-06 2018-08-09 Bioclin Therapeutics, Inc. Methods, compositions, and kits for treatment of cancer
WO2019067092A1 (en) * 2017-08-07 2019-04-04 The Johns Hopkins University METHODS AND SUBSTANCES FOR THE EVALUATION AND TREATMENT OF CANCER

Family Cites Families (4)

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EP2945652B1 (en) * 2013-01-18 2021-07-07 Foundation Medicine, Inc. Methods of treating cholangiocarcinoma
CN103757026B (zh) * 2013-12-20 2017-04-05 广州圣露生物技术有限公司 FGFR2b胞外段的基因序列、多肽及其应用
EP4063516A1 (en) * 2014-09-26 2022-09-28 Janssen Pharmaceutica NV Use of fgfr mutant gene panels in identifying cancer patients that will be responsive to treatment with an fgfr inhibitor
MA47408B1 (fr) * 2017-12-20 2023-08-31 Janssen Pharmaceutica Nv Traitement du cancer

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009523410A (ja) * 2005-12-08 2009-06-25 ノバルティス アクチエンゲゼルシャフト 遺伝子転写に対するfgfr3の阻害剤の効果
JP2017511792A (ja) * 2013-12-18 2017-04-27 イムクローン リミテッド ライアビリティ カンパニー 繊維芽細胞増殖因子受容体3(fgfr3)に対する化合物および治療的使用
WO2018145120A1 (en) * 2017-02-06 2018-08-09 Bioclin Therapeutics, Inc. Methods, compositions, and kits for treatment of cancer
WO2019067092A1 (en) * 2017-08-07 2019-04-04 The Johns Hopkins University METHODS AND SUBSTANCES FOR THE EVALUATION AND TREATMENT OF CANCER

Non-Patent Citations (5)

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Title
"Infigratinib in upper tract urothelial carcinoma vs urothelial carcinoma of the bladder and associat", JOURNAL OF CLINICAL ONCOLOGY, vol. Vol.37, No.15_suppl, JPN6024015680, 26 May 2019 (2019-05-26), pages 4510, ISSN: 0005519416 *
CANCER DISCOVERY, vol. 8, no. 7, JPN6024015682, 2018, pages 812 - 821, ISSN: 0005309676 *
JOURNAL OF CLINICAL ONCOLOGY, vol. 35, no. 2, JPN6024015683, 2017, pages 157 - 175, ISSN: 0005309677 *
UROLOGIC ONCOLOGY: SEMINARS AND ORIGINAL INVESTIGATIONS, vol. 35, no. 8, JPN6024015681, August 2017 (2017-08-01), pages 516 - 527, ISSN: 0005309675 *
腎盂・尿管癌診療ガイドライン2014年版, JPN6025003411, 2014, pages 49 - 50, ISSN: 0005519417 *

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SG11202112932QA (en) 2021-12-30
CN114207151A (zh) 2022-03-18
IL288408A (en) 2022-01-01
EP3976833A4 (en) 2023-07-05
AU2020282816A1 (en) 2022-01-06
EP3976833A1 (en) 2022-04-06
KR20220088830A (ko) 2022-06-28
WO2020243442A1 (en) 2020-12-03
US20220233537A1 (en) 2022-07-28
MX2021014524A (es) 2022-05-19
PH12021552973A1 (en) 2022-07-11
CA3141871A1 (en) 2020-12-03

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