JP2022533673A5 - - Google Patents
Info
- Publication number
- JP2022533673A5 JP2022533673A5 JP2021568855A JP2021568855A JP2022533673A5 JP 2022533673 A5 JP2022533673 A5 JP 2022533673A5 JP 2021568855 A JP2021568855 A JP 2021568855A JP 2021568855 A JP2021568855 A JP 2021568855A JP 2022533673 A5 JP2022533673 A5 JP 2022533673A5
- Authority
- JP
- Japan
- Prior art keywords
- tada
- rett
- mecp2
- adenosine deaminase
- amino acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962850919P | 2019-05-21 | 2019-05-21 | |
| US62/850,919 | 2019-05-21 | ||
| PCT/US2020/033807 WO2020236936A1 (en) | 2019-05-21 | 2020-05-20 | Methods of editing a single nucleotide polymorphism using programmable base editor systems |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022533673A JP2022533673A (ja) | 2022-07-25 |
| JP2022533673A5 true JP2022533673A5 (enExample) | 2023-05-29 |
| JP7679311B2 JP7679311B2 (ja) | 2025-05-19 |
Family
ID=73459015
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021568855A Active JP7679311B2 (ja) | 2019-05-21 | 2020-05-20 | プログラム可能塩基エディターシステムを用いた一塩基多型編集法 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20220387622A1 (enExample) |
| EP (1) | EP3972654A4 (enExample) |
| JP (1) | JP7679311B2 (enExample) |
| KR (1) | KR20220010540A (enExample) |
| CN (2) | CN114206395B (enExample) |
| AU (1) | AU2020279751A1 (enExample) |
| CA (1) | CA3140093A1 (enExample) |
| WO (1) | WO2020236936A1 (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL3765615T3 (pl) | 2018-03-14 | 2023-11-13 | Arbor Biotechnologies, Inc. | Nowe enzymy i układy crispr ukierunkowane na dna |
| WO2019217942A1 (en) | 2018-05-11 | 2019-11-14 | Beam Therapeutics Inc. | Methods of substituting pathogenic amino acids using programmable base editor systems |
| WO2019222555A1 (en) | 2018-05-16 | 2019-11-21 | Arbor Biotechnologies, Inc. | Novel crispr-associated systems and components |
| EP3850088A4 (en) | 2018-09-07 | 2023-07-19 | Beam Therapeutics, Inc. | Compositions and methods for improving base editing |
| KR20210055733A (ko) | 2018-09-07 | 2021-05-17 | 빔 테라퓨틱스, 인크. | 핵염기 편집 시스템을 전달하기 위한 조성물 및 방법 |
| EP3924479A4 (en) * | 2019-02-13 | 2023-01-25 | Beam Therapeutics, Inc. | ADENOSINE DEAMINASE BASE EDITORS AND METHODS OF USING THEM TO MODIFY A NUCLEOBASE IN A TARGET SEQUENCE |
| WO2020168135A1 (en) | 2019-02-13 | 2020-08-20 | Beam Therapeutics Inc. | Compositions and methods for treating alpha-1 antitrypsin deficiency |
| US12600971B2 (en) | 2019-02-13 | 2026-04-14 | Beam Therapeutics Inc. | Modified immune cells having adenosine deaminase base editors for modifying a nucleobase in a target sequence |
| US12594301B2 (en) | 2019-09-27 | 2026-04-07 | Beam Therapeutics Inc. | Compositions and methods for treatment of liquid cancers |
| AU2021347359A1 (en) | 2020-09-25 | 2023-05-18 | Beam Therapeutics Inc. | Fratricide resistant modified immune cells and methods of using the same |
| EP4396207A4 (en) * | 2021-09-03 | 2025-07-16 | Univ Chicago | POLYPEPTIDES AND METHODS FOR MODIFYING NUCLEIC ACIDS |
| EP4404942A4 (en) * | 2021-09-26 | 2026-06-17 | Wave Life Sciences Ltd | Compositions for the Editing of Transcripts MECP2 and Related Processes |
| WO2023140694A1 (ko) * | 2022-01-24 | 2023-07-27 | 주식회사 툴젠 | 스트렙토코커스 피오게네스 유래 cas9 변이체 |
| CA3266991A1 (en) * | 2022-09-08 | 2024-03-14 | The University Court Of The University Of Edinburgh | TREATMENT OF RETT SYNDROME |
| WO2024102811A2 (en) * | 2022-11-08 | 2024-05-16 | The Board Of Trustees Of The Leland Stanford Junior University | Muscle-specific base editors for correction of mutations causing- dilated cardiomyopathy |
| CN117965505A (zh) * | 2023-06-28 | 2024-05-03 | 微光基因(苏州)有限公司 | 工程化的腺苷脱氨酶及碱基编辑器 |
| JP2026524490A (ja) * | 2023-07-07 | 2026-07-22 | ミリアド ジェネティクス，インコーポレーテッド | 乳がんについての多祖先ポリジェニックリスク評価 |
| WO2025199339A2 (en) * | 2024-03-20 | 2025-09-25 | Shape Therapeutics Inc. | Mecp2-targeting engineered guide rnas and polynucleotides |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG11201510327TA (en) * | 2013-06-17 | 2016-01-28 | Broad Inst Inc | Delivery, engineering and optimization of systems, methods and compositions for targeting and modeling diseases and disorders of post mitotic cells |
| KR20250012194A (ko) * | 2013-06-17 | 2025-01-23 | 더 브로드 인스티튜트, 인코퍼레이티드 | 바이러스 구성성분을 사용하여 장애 및 질환을 표적화하기 위한 crispr-cas 시스템 및 조성물의 전달, 용도 및 치료 적용 |
| EP3957731A1 (en) * | 2015-07-15 | 2022-02-23 | Rutgers, The State University of New Jersey | Nuclease-independent targeted gene editing platform and uses thereof |
| WO2018027078A1 (en) * | 2016-08-03 | 2018-02-08 | President And Fellows Of Harard College | Adenosine nucleobase editors and uses thereof |
| RU2019133002A (ru) * | 2017-03-24 | 2021-04-26 | Зе Юнивёрсити Корт Оф Зе Юнивёрсити Оф Эдинбург | ЭКСПРЕССИОННЫЕ КАССЕТЫ MeCP2 |
| IL316453A (en) * | 2017-10-06 | 2024-12-01 | Univ Oregon Health & Science | RNA editing agents and methods |
| CA3082251A1 (en) * | 2017-10-16 | 2019-04-25 | The Broad Institute, Inc. | Uses of adenosine base editors |
| EP3699267A4 (en) | 2017-10-17 | 2021-10-27 | Kyoto University | METHOD OF MANUFACTURING AN ARTIFICIAL NEUROMUSCULAR END PLATE FROM PLURIPOTENT STEM CELLS |
| KR102853088B1 (ko) * | 2018-05-11 | 2025-09-02 | 빔 테라퓨틱스, 인크. | 프로그래밍가능한 염기 편집기 시스템을 이용하여 단일염기다형성을 편집하는 방법 |
-
2020
- 2020-05-20 JP JP2021568855A patent/JP7679311B2/ja active Active
- 2020-05-20 EP EP20809005.0A patent/EP3972654A4/en active Pending
- 2020-05-20 KR KR1020217041287A patent/KR20220010540A/ko active Pending
- 2020-05-20 CN CN202080052684.3A patent/CN114206395B/zh active Active
- 2020-05-20 CN CN202510277023.5A patent/CN120346348A/zh active Pending
- 2020-05-20 CA CA3140093A patent/CA3140093A1/en active Pending
- 2020-05-20 WO PCT/US2020/033807 patent/WO2020236936A1/en not_active Ceased
- 2020-05-20 US US17/612,879 patent/US20220387622A1/en active Pending
- 2020-05-20 AU AU2020279751A patent/AU2020279751A1/en active Pending
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