JP2022545950A5 - - Google Patents
Info
- Publication number
- JP2022545950A5 JP2022545950A5 JP2022513443A JP2022513443A JP2022545950A5 JP 2022545950 A5 JP2022545950 A5 JP 2022545950A5 JP 2022513443 A JP2022513443 A JP 2022513443A JP 2022513443 A JP2022513443 A JP 2022513443A JP 2022545950 A5 JP2022545950 A5 JP 2022545950A5
- Authority
- JP
- Japan
- Prior art keywords
- tada
- spcas9
- variant
- deaminase
- sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025135451A JP2025183226A (ja) | 2019-08-29 | 2025-08-15 | 転写または発現を可能にするように変異を編集するための組成物および方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962893638P | 2019-08-29 | 2019-08-29 | |
| US62/893,638 | 2019-08-29 | ||
| PCT/US2020/048510 WO2021041885A2 (en) | 2019-08-29 | 2020-08-28 | Compositions and methods for editing a mutation to permit transcription or expression |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025135451A Division JP2025183226A (ja) | 2019-08-29 | 2025-08-15 | 転写または発現を可能にするように変異を編集するための組成物および方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022545950A JP2022545950A (ja) | 2022-11-01 |
| JP2022545950A5 true JP2022545950A5 (enExample) | 2023-09-05 |
| JP7781742B2 JP7781742B2 (ja) | 2025-12-08 |
Family
ID=74684607
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022513443A Active JP7781742B2 (ja) | 2019-08-29 | 2020-08-28 | 転写または発現を可能にするように変異を編集するための組成物および方法 |
| JP2025135451A Pending JP2025183226A (ja) | 2019-08-29 | 2025-08-15 | 転写または発現を可能にするように変異を編集するための組成物および方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025135451A Pending JP2025183226A (ja) | 2019-08-29 | 2025-08-15 | 転写または発現を可能にするように変異を編集するための組成物および方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20220313799A1 (enExample) |
| EP (1) | EP4022050A4 (enExample) |
| JP (2) | JP7781742B2 (enExample) |
| KR (1) | KR20220066289A (enExample) |
| CN (2) | CN119913134A (enExample) |
| AU (1) | AU2020336953A1 (enExample) |
| CA (1) | CA3152861A1 (enExample) |
| WO (1) | WO2021041885A2 (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2019336245B2 (en) | 2018-09-07 | 2026-02-26 | Beam Therapeutics Inc. | Compositions and methods for delivering a nucleobase editing system |
| CN114258398A (zh) | 2019-06-13 | 2022-03-29 | 总医院公司 | 工程化的人内源性病毒样颗粒及使用其递送至细胞的方法 |
| WO2021222318A1 (en) | 2020-04-28 | 2021-11-04 | The Broad Institute, Inc. | Targeted base editing of the ush2a gene |
| CN116670154A (zh) | 2020-07-24 | 2023-08-29 | 总医院公司 | 增强的病毒样颗粒及使用其递送至细胞的方法 |
| WO2022194224A1 (zh) * | 2021-03-16 | 2022-09-22 | 上海驯鹿生物技术有限公司 | 通用型嵌合抗原受体t细胞及其应用 |
| WO2022221699A1 (en) * | 2021-04-16 | 2022-10-20 | Beam Therapeutics, Inc. | Genetic modification of hepatocytes |
| KR20240012377A (ko) * | 2021-05-28 | 2024-01-29 | 빔 테라퓨틱스, 인크. | 염기 편집기의 자기-불활성화용 조성물 및 방법 |
| CA3239381A1 (en) | 2021-12-03 | 2023-06-08 | David R. Liu | Compositions and methods for efficient in vivo delivery |
| CN120303407A (zh) | 2022-05-17 | 2025-07-11 | 恩维洛普治疗有限责任公司 | 用于有效体内递送的组合物和方法 |
| KR20230166378A (ko) | 2022-05-30 | 2023-12-07 | 현대자동차주식회사 | 차량의 제동 방법 및 장치 |
| WO2024138131A1 (en) * | 2022-12-22 | 2024-06-27 | Trustees Of Tufts College | Expanding applications of zgtc alphabet in protein expression and gene editing |
| WO2025064656A1 (en) * | 2023-09-19 | 2025-03-27 | Beam Therapeutics Inc. | Compositions and methods for altering a nucleobase in a lipoprotein(a) polynucleotide |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2003258437A1 (en) | 2002-08-30 | 2004-03-19 | The Hospital For Sick Children | Diagnosis of shwachman-diamond syndrome |
| US20110151447A1 (en) * | 2007-11-06 | 2011-06-23 | Children's Medical Center Corporation | Method to produce induced pluripotent stem (ips) cells from non-embryonic human cells |
| EP3919621A1 (en) * | 2014-06-23 | 2021-12-08 | The General Hospital Corporation | Genomewide unbiased identification of dsbs evaluated by sequencing (guide-seq) |
| SG10202104041PA (en) * | 2015-10-23 | 2021-06-29 | Harvard College | Nucleobase editors and uses thereof |
| WO2018119359A1 (en) * | 2016-12-23 | 2018-06-28 | President And Fellows Of Harvard College | Editing of ccr5 receptor gene to protect against hiv infection |
| EP3610009A1 (en) * | 2017-04-12 | 2020-02-19 | The Broad Institute, Inc. | Novel type vi crispr orthologs and systems |
| US11795443B2 (en) * | 2017-10-16 | 2023-10-24 | The Broad Institute, Inc. | Uses of adenosine base editors |
| CN109306361B (zh) * | 2018-02-11 | 2022-06-28 | 华东师范大学 | 一种新的a/t到g/c碱基定点转换的基因编辑系统 |
-
2020
- 2020-08-28 CN CN202411970155.8A patent/CN119913134A/zh active Pending
- 2020-08-28 AU AU2020336953A patent/AU2020336953A1/en active Pending
- 2020-08-28 JP JP2022513443A patent/JP7781742B2/ja active Active
- 2020-08-28 US US17/638,757 patent/US20220313799A1/en active Pending
- 2020-08-28 KR KR1020227010126A patent/KR20220066289A/ko active Pending
- 2020-08-28 CA CA3152861A patent/CA3152861A1/en active Pending
- 2020-08-28 CN CN202080076243.7A patent/CN114641567B/zh active Active
- 2020-08-28 WO PCT/US2020/048510 patent/WO2021041885A2/en not_active Ceased
- 2020-08-28 EP EP20856306.4A patent/EP4022050A4/en active Pending
-
2025
- 2025-08-15 JP JP2025135451A patent/JP2025183226A/ja active Pending
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