JP2025102768A5 - - Google Patents
Info
- Publication number
- JP2025102768A5 JP2025102768A5 JP2025033734A JP2025033734A JP2025102768A5 JP 2025102768 A5 JP2025102768 A5 JP 2025102768A5 JP 2025033734 A JP2025033734 A JP 2025033734A JP 2025033734 A JP2025033734 A JP 2025033734A JP 2025102768 A5 JP2025102768 A5 JP 2025102768A5
- Authority
- JP
- Japan
- Prior art keywords
- hbv
- gene
- cas9
- domain
- nucleic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962846422P | 2019-05-10 | 2019-05-10 | |
| US62/846,422 | 2019-05-10 | ||
| US201962927585P | 2019-10-29 | 2019-10-29 | |
| US62/927,585 | 2019-10-29 | ||
| JP2021566276A JP7679309B2 (ja) | 2019-05-10 | 2020-05-08 | Ｂ型肝炎を治療するための組成物及び方法 |
| PCT/US2020/032226 WO2020231863A1 (en) | 2019-05-10 | 2020-05-08 | Compositions and methods for treating hepatitis b |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021566276A Division JP7679309B2 (ja) | 2019-05-10 | 2020-05-08 | Ｂ型肝炎を治療するための組成物及び方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2025102768A JP2025102768A (ja) | 2025-07-08 |
| JP2025102768A5 true JP2025102768A5 (enExample) | 2025-08-13 |
Family
ID=73289231
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021566276A Active JP7679309B2 (ja) | 2019-05-10 | 2020-05-08 | Ｂ型肝炎を治療するための組成物及び方法 |
| JP2025033734A Pending JP2025102768A (ja) | 2019-05-10 | 2025-03-04 | Ｂ型肝炎を治療するための組成物及び方法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021566276A Active JP7679309B2 (ja) | 2019-05-10 | 2020-05-08 | Ｂ型肝炎を治療するための組成物及び方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20230070861A1 (enExample) |
| EP (1) | EP3965832A4 (enExample) |
| JP (2) | JP7679309B2 (enExample) |
| KR (1) | KR20220019685A (enExample) |
| CN (2) | CN120586100A (enExample) |
| AU (1) | AU2020276218A1 (enExample) |
| CA (1) | CA3139324A1 (enExample) |
| WO (1) | WO2020231863A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20230159913A1 (en) | 2020-04-28 | 2023-05-25 | The Broad Institute, Inc. | Targeted base editing of the ush2a gene |
| WO2022170059A1 (en) | 2021-02-05 | 2022-08-11 | Christiana Care Health Services, Inc. | Methods of and compositions for reducing gene expression and/or activity |
| WO2022192634A1 (en) * | 2021-03-12 | 2022-09-15 | Massachusetts Institute Of Technology | Compositions and methods for dominant antiviral therapy |
| KR20240087635A (ko) * | 2021-07-22 | 2024-06-19 | 에멘도바이오 인코포레이티드 | B형 간염 바이러스(hbv) 녹아웃 |
| JP2024534639A (ja) * | 2021-09-27 | 2024-09-20 | ビーム セラピューティクス インク． | Ｂ型肝炎ウイルス感染症を治療するための組成物及び方法 |
| WO2024103049A1 (en) * | 2022-11-11 | 2024-05-16 | The United States Government As Represented By The Department Of Veterans Affairs | Cd33 specific exosomes and uses thereof |
| WO2024186890A1 (en) * | 2023-03-06 | 2024-09-12 | Intellia Therapeutics, Inc. | Compositions and methods for hepatitis b virus (hbv) genome editing |
| AU2024270764A1 (en) | 2023-05-15 | 2025-12-04 | Nchroma Bio, Inc. | Compositions and methods for epigenetic regulation of hbv gene expression |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107995927B (zh) * | 2013-06-17 | 2021-07-30 | 布罗德研究所有限公司 | 用于肝靶向和治疗的crispr-cas系统、载体和组合物的递送与用途 |
| EP3540051B1 (en) * | 2013-12-12 | 2022-08-17 | The Broad Institute, Inc. | Delivery, use and therapeutic applications of the crispr-cas systems and compositions for hsv and viral diseases and disorders. |
| AU2016341919A1 (en) * | 2015-10-21 | 2018-04-19 | Editas Medicine, Inc. | CRISPR/CAS-related methods and compositions for treating hepatitis b virus |
| KR20250103795A (ko) * | 2016-08-03 | 2025-07-07 | 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 | 아데노신 핵염기 편집제 및 그의 용도 |
| JP7219972B2 (ja) * | 2017-01-05 | 2023-02-09 | ラトガース，ザ ステート ユニバーシティ オブ ニュー ジャージー | Ｄｎａ二本鎖切断に非依存的な標的化遺伝子編集プラットフォームおよびその用途 |
| WO2019005886A1 (en) * | 2017-06-26 | 2019-01-03 | The Broad Institute, Inc. | CRISPR / CAS-CYTIDINE DEAMINASE COMPOSITIONS, SYSTEMS AND METHODS FOR TARGETED EDITING OF NUCLEIC ACIDS |
| CN111801345A (zh) * | 2017-07-28 | 2020-10-20 | 哈佛大学的校长及成员们 | 使用噬菌体辅助连续进化(pace)的进化碱基编辑器的方法和组合物 |
-
2020
- 2020-05-08 JP JP2021566276A patent/JP7679309B2/ja active Active
- 2020-05-08 US US17/610,119 patent/US20230070861A1/en active Pending
- 2020-05-08 EP EP20806106.9A patent/EP3965832A4/en active Pending
- 2020-05-08 CN CN202510594053.9A patent/CN120586100A/zh active Pending
- 2020-05-08 WO PCT/US2020/032226 patent/WO2020231863A1/en not_active Ceased
- 2020-05-08 KR KR1020217039921A patent/KR20220019685A/ko active Pending
- 2020-05-08 CN CN202080050214.3A patent/CN114929287B/zh active Active
- 2020-05-08 CA CA3139324A patent/CA3139324A1/en active Pending
- 2020-05-08 AU AU2020276218A patent/AU2020276218A1/en active Pending
-
2025
- 2025-03-04 JP JP2025033734A patent/JP2025102768A/ja active Pending