JP2022530966A5 - - Google Patents

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JP2022530966A5
JP2022530966A5 JP2021564491A JP2021564491A JP2022530966A5 JP 2022530966 A5 JP2022530966 A5 JP 2022530966A5 JP 2021564491 A JP2021564491 A JP 2021564491A JP 2021564491 A JP2021564491 A JP 2021564491A JP 2022530966 A5 JP2022530966 A5 JP 2022530966A5
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nucleic acid
analyte
solid support
chimera
captured
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JP7582676B2 (ja
JP2022530966A (ja
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JP2021564491A 2019-04-30 2020-04-10 分析物を調製するための方法および関連キット Active JP7582676B2 (ja)

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US201962840675P 2019-04-30 2019-04-30
US62/840,675 2019-04-30
PCT/US2020/027840 WO2020223000A1 (en) 2019-04-30 2020-04-10 Methods for preparing analytes and related kits

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JP2022530966A JP2022530966A (ja) 2022-07-05
JP2022530966A5 true JP2022530966A5 (enExample) 2023-05-24
JP7582676B2 JP7582676B2 (ja) 2024-11-13

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US (2) US11634709B2 (enExample)
EP (1) EP3963070A4 (enExample)
JP (1) JP7582676B2 (enExample)
CN (1) CN114072499B (enExample)
AU (1) AU2020267119B2 (enExample)
CA (1) CA3138367A1 (enExample)
WO (1) WO2020223000A1 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2020004559A (es) 2017-10-31 2020-10-05 Encodia Inc Kits para análisis utilizando codificación y/o etiqueta de ácido nucleico.
EP3963070A4 (en) 2019-04-30 2023-02-22 Encodia, Inc. METHODS OF PREPARATION OF ANALYTES AND RELATED KITS
WO2021141924A1 (en) 2020-01-07 2021-07-15 Encodia, Inc. Methods for stable complex formation and related kits
CN116685725A (zh) 2020-08-19 2023-09-01 Encodia 公司 顺序编码方法和相关试剂盒
WO2022094148A1 (en) * 2020-10-30 2022-05-05 Encodia, Inc. Conjugation reagents and methods using 1,2-cyclohexanediones
US12474346B2 (en) 2021-11-05 2025-11-18 Encodia, Inc. Methods and kits for multicycle encoding assay
WO2023086847A1 (en) 2021-11-10 2023-05-19 Encodia, Inc. Methods for barcoding macromolecules in individual cells
EP4206674B1 (en) 2021-12-28 2025-10-22 Encodia, Inc. High-throughput serotyping and antibody profiling assays
US20240003886A1 (en) * 2022-06-15 2024-01-04 Quantum-Si Incorporated Directed protein evolution
EP4565882A1 (en) 2022-08-02 2025-06-11 Glyphic Biotechnologies, Inc. Protein sequencing via coupling of polymerizable molecules
WO2026002230A1 (en) * 2024-06-28 2026-01-02 Syncell (Taiwan) Inc. Kits for biotin-streptavidin pulldown system and method

Family Cites Families (125)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4863870A (en) 1988-03-10 1989-09-05 Bio-Affinity Systems, Inc. Method of thioacylation peptide sequencing with alcoholysis of thiazolinones
US5049507A (en) 1989-12-21 1991-09-17 Applied Biosystems, Inc. Method of C-terminal peptide sequencing
US5573905A (en) 1992-03-30 1996-11-12 The Scripps Research Institute Encoded combinatorial chemical libraries
SE9400088D0 (sv) 1994-01-14 1994-01-14 Kabi Pharmacia Ab Bacterial receptor structures
US5834252A (en) 1995-04-18 1998-11-10 Glaxo Group Limited End-complementary polymerase reaction
CA2176414A1 (en) 1995-05-18 1996-11-19 S. David Kimball Acyl guanidine and amidine prodrugs
EP0841945B1 (en) 1995-08-03 2006-03-08 Rijksuniversiteit te Leiden Cell derived antigen presenting vesicles
US5770365A (en) * 1995-08-25 1998-06-23 Tm Technologies, Inc. Nucleic acid capture moieties
US5900481A (en) 1996-11-06 1999-05-04 Sequenom, Inc. Bead linkers for immobilizing nucleic acids to solid supports
US6306588B1 (en) 1997-02-07 2001-10-23 Invitrogen Corporation Polymerases for analyzing or typing polymorphic nucleic acid fragments and uses thereof
EP1068356B8 (en) 1998-04-03 2007-01-03 Adnexus Therapeutics, Inc. Addressable protein arrays
US6875851B1 (en) 1999-03-05 2005-04-05 University Of Georgia Research Foundation, Inc. Prolyl tripeptidyl peptidases nucleic acid of Porphyromonas gingivalis
SK13242001A3 (sk) 1999-03-23 2002-09-10 Biovation Limited Izolácia a analýza proteínov
AU5723700A (en) 1999-05-25 2000-12-12 Praelux Incorporated Method for sequency and characterizing polymeric biomolecules using aptamers anda method for producing aptamers
GB9927320D0 (en) 1999-11-18 2000-01-12 Chiron Spa Exosome separation
US7306904B2 (en) 2000-02-18 2007-12-11 Olink Ab Methods and kits for proximity probing
AU2001241939A1 (en) * 2000-02-28 2001-09-12 Maxygen, Inc. Single-stranded nucleic acid template-mediated recombination and nucleic acid fragment isolation
US6511809B2 (en) * 2000-06-13 2003-01-28 E. I. Du Pont De Nemours And Company Method for the detection of an analyte by means of a nucleic acid reporter
CA2314398A1 (en) 2000-08-10 2002-02-10 Edward Shipwash Microarrays and microsystems for amino acid analysis and protein sequencing
US20030087232A1 (en) 2001-01-25 2003-05-08 Fred Christians Methods for screening polypeptides
US7727713B2 (en) 2001-06-20 2010-06-01 Nuevolution A/S Templated molecules and methods for using such molecules
US7169894B2 (en) 2001-11-14 2007-01-30 Mirari Biosciences, Inc. Methods and compositions for reverse translation
US8013134B2 (en) 2001-11-23 2011-09-06 Olink Ab Kit for proximity probing with multivalent proximity probes
CA2501645A1 (en) 2002-10-10 2004-04-22 Verenium Corporation Proteases, nucleic acids encoding them and methods for making and using them
US20090246879A1 (en) 2002-12-20 2009-10-01 Callida Genomics Materials and Methods Relating to Nano-Tags and Nano-Brands
WO2005015239A2 (en) 2003-08-07 2005-02-17 Cornell Research Foundation, Inc. Method for n-terminal labeling of proteins
US7198900B2 (en) 2003-08-29 2007-04-03 Applera Corporation Multiplex detection compositions, methods, and kits
ATE447626T1 (de) 2003-09-18 2009-11-15 Nuevolution As Methode zur gewinnung struktureller informationen kodierter moleküle und zur selektion von verbindungen
US7579165B2 (en) 2003-10-16 2009-08-25 Shimadzu Corporation Methods for derivatizing protein or peptide with sulfonic acid groups
GB0326073D0 (en) * 2003-11-07 2003-12-10 Solexa Ltd Improvements in or relating to polynucleotide arrays
CN1898257B (zh) 2003-12-17 2010-06-23 普雷西斯药品公司 合成编码文库的方法
GB0404187D0 (en) 2004-02-25 2004-03-31 Biotransformations Ltd Binding agents
WO2005090566A2 (en) 2004-03-22 2005-09-29 Nuevolution A/S Ligational encoding using building block oligonucleotides
CN1296492C (zh) * 2004-11-18 2007-01-24 博奥生物有限公司 一种基于生物芯片检测能结合特异序列的核酸结合蛋白的方法
US7393665B2 (en) 2005-02-10 2008-07-01 Population Genetics Technologies Ltd Methods and compositions for tagging and identifying polynucleotides
US20060199279A1 (en) 2005-03-07 2006-09-07 Viorica Lopez-Avila Methods for identifying post-translationally modified polypeptides
US20070020640A1 (en) 2005-07-21 2007-01-25 Mccloskey Megan L Molecular encoding of nucleic acid templates for PCR and other forms of sequence analysis
US20100261615A9 (en) * 2005-08-12 2010-10-14 Joon Won Park Atomic force microscope as an analyzing tool for biochip
EP1915466B1 (en) * 2005-08-19 2010-11-24 Nanosphere, Inc. Methods for preparing hybrid substrates comprising dna and antibodies and uses thereof
US7611834B2 (en) 2005-09-30 2009-11-03 Sandia Corporation Methods and devices for protein assays
LT3018206T (lt) 2005-12-01 2021-12-10 Nuevolution A/S Fermentiniai kodavimo būdai, skirti didelių bibliotekų efektyviai sintezei
US20070218503A1 (en) 2006-02-13 2007-09-20 Mitra Robi D Methods of polypeptide identification, and compositions therefor
DE102006015001A1 (de) 2006-03-31 2007-10-11 NMI Naturwissenschaftliches und Medizinisches Institut an der Universität Tübingen Verfahren zum Nachweis und/oder zur Anreicherung von Analytproteinen und/oder Analytpeptiden aus einer komplexen Proteinmischung
US8758991B2 (en) 2006-04-26 2014-06-24 University Of Louisville Research Foundation, Inc. Isolation of membrane vesicles from biological fluids and methods of using same
US8349167B2 (en) 2006-12-14 2013-01-08 Life Technologies Corporation Methods and apparatus for detecting molecular interactions using FET arrays
US20110136099A1 (en) * 2007-01-16 2011-06-09 Somalogic, Inc. Multiplexed Analyses of Test Samples
US20080242622A1 (en) * 2007-03-19 2008-10-02 Cold Spring Harbor Laboratory Identification of genetic alterations that modulate drug sensitivity in cancer treatments
WO2009019215A1 (en) 2007-08-03 2009-02-12 Dkfz Deutsches Krebsforschungszentrum Method for prenatal diagnosis using exosomes and cd24 as a marker
US20100311114A1 (en) 2007-10-19 2010-12-09 Pronota N.V. Preparation of samples for proteome analysis
CA2745197A1 (en) 2008-12-01 2010-06-10 Research Triangle Institute Concurrent identification of multitudes of polypeptides
WO2010065531A1 (en) 2008-12-01 2010-06-10 Robi David Mitra Single molecule protein screening
US9085798B2 (en) 2009-04-30 2015-07-21 Prognosys Biosciences, Inc. Nucleic acid constructs and methods of use
US9566335B1 (en) 2009-09-25 2017-02-14 The Governing Council Of The University Of Toronto Protein sequencing method and reagents
WO2011056185A2 (en) 2009-11-04 2011-05-12 President And Fellows Of Harvard College Reactivity-dependent and interaction-dependent pcr
KR101866401B1 (ko) 2010-04-05 2018-06-11 프로그노시스 바이오사이언스, 인코포레이티드 공간적으로 엔코딩된 생물학적 검정
KR20130043104A (ko) 2010-04-06 2013-04-29 카리스 라이프 사이언스 룩셈부르크 홀딩스 질병용 순환 생물학적 지표들
WO2011143583A1 (en) 2010-05-13 2011-11-17 Illumina, Inc. Binding assays for markers
CN103119165B (zh) 2010-09-27 2017-04-12 威泊根私人有限公司 制备富集文库的方法
CA2817111C (en) 2010-11-10 2019-03-05 Exosome Diagnostics, Inc. Method for isolation of nucleic acid containing particles and extraction of nucleic acids therefrom
GB201101621D0 (en) 2011-01-31 2011-03-16 Olink Ab Method and product
WO2012112804A1 (en) 2011-02-18 2012-08-23 Raindance Technoligies, Inc. Compositions and methods for molecular labeling
EP3246416B1 (en) 2011-04-15 2024-06-05 The Johns Hopkins University Safe sequencing system
CA2835641C (en) 2011-05-11 2019-05-28 Exosome Diagnostics, Inc. Nucleic acid extraction from heterogeneous biological materials
WO2016069124A1 (en) 2014-09-15 2016-05-06 Board Of Regents, The University Of Texas System Improved single molecule peptide sequencing
GB2577626B (en) 2011-06-23 2020-09-23 Univ Texas Identifying peptides at the single molecule level
EP3492606B1 (en) 2011-08-22 2023-10-04 Exosome Diagnostics, Inc. Urine biomarkers
US20130052665A1 (en) 2011-08-25 2013-02-28 Bruce Xuefeng Ling Methods for diagnosis of systemic juvenile idiopathic arthritis
US9335292B2 (en) 2011-10-13 2016-05-10 Auburn University Electrochemical proximity assay
EP2776587A4 (en) 2011-11-10 2015-07-15 Exosome Diagnostics Inc LIQUOR ASSAY
US20150087526A1 (en) 2012-01-24 2015-03-26 The Regents Of The University Of Colorado, A Body Corporate Peptide identification and sequencing by single-molecule detection of peptides undergoing degradation
SMT202100154T1 (it) 2012-02-17 2021-05-07 Hutchinson Fred Cancer Res Composizioni e metodi per identificare precisamente mutazioni
US9862995B2 (en) 2012-03-13 2018-01-09 Abhijit Ajit Patel Measurement of nucleic acid variants using highly-multiplexed error-suppressed deep sequencing
WO2013142389A1 (en) 2012-03-20 2013-09-26 University Of Washington Through Its Center For Commercialization Methods of lowering the error rate of massively parallel dna sequencing using duplex consensus sequencing
US9005888B2 (en) 2012-06-14 2015-04-14 System Biosciences, Llc Methods for microvesicle isolation and selective removal
NL2009191C2 (en) 2012-07-16 2014-01-20 Univ Delft Tech Single molecule protein sequencing.
US20140378322A1 (en) 2012-08-14 2014-12-25 10X Technologies, Inc. Compositions and methods for sample processing
US20150252428A1 (en) 2012-10-03 2015-09-10 Exosome Diagnostics, Inc. Use of microvesicles in diagnosis, prognosis, and treatment of medical diseases and conditions
AU2013340414B2 (en) 2012-10-23 2019-05-02 Caris Science, Inc. Aptamers and uses thereof
WO2014142981A1 (en) 2013-03-15 2014-09-18 Illumina, Inc. Enzyme-linked nucleotides
US9435810B2 (en) 2013-03-15 2016-09-06 Washington University Molecules and methods for iterative polypeptide analysis and processing
WO2014176355A1 (en) 2013-04-23 2014-10-30 President And Fellows Of Harvard College In situ interaction determination
CN111500680B (zh) 2013-06-25 2024-04-16 普罗格诺西斯生物科学公司 检测样品中生物靶标的空间分布的方法和系统
BR112016004153A2 (pt) 2013-08-28 2019-09-17 Caris Life Sciences Switzerland Holdings Gmbh "método para caracterizar uma doença ou distúrbio, kit, composição, método para gerar uma biblioteca de entrada, oligonucleotídeo, pluralidade de oligonucleotídeos e método para identificar um aptâmero
WO2015042506A1 (en) 2013-09-23 2015-03-26 The Trustees Of Columbia University In The City Of New York High-throughput single molecule protein identification
JP6156962B2 (ja) 2014-02-27 2017-07-05 ボード・オブ・リージエンツ,ザ・ユニバーシテイ・オブ・テキサス・システム エキソソームを単離するための方法および組成物
US10858698B2 (en) 2014-03-25 2020-12-08 President And Fellows Of Harvard College Barcoded protein array for multiplex single-molecule interaction profiling
EP3134536B1 (en) 2014-04-21 2019-12-18 President and Fellows of Harvard College Systems and methods for barcoding nucleic acids
WO2015163818A1 (en) 2014-04-24 2015-10-29 Nanyang Technological University Asx-specific protein ligase
WO2015166768A1 (ja) 2014-05-02 2015-11-05 国立大学法人金沢大学 単一細胞由来核酸の解析方法
EP3143165A4 (en) 2014-05-15 2018-05-16 Two Pore Guys, Inc. Scaffold data storage and target detection in a sample using a nanopore
EP4574974A3 (en) 2014-06-26 2025-10-08 10x Genomics, Inc. Methods of analyzing nucleic acids from individual cells or cell populations
KR20170026383A (ko) 2014-06-26 2017-03-08 10엑스 제노믹스, 인크. 핵산 서열의 분석
US11229607B2 (en) 2014-06-30 2022-01-25 President And Fellows Of Harvard College Hydrogel compositions comprising encapsulated cells and methods of use thereof
SG11201700146QA (en) 2014-07-09 2017-02-27 Exosome Diagnostics Inc Methods for isolating microvesicles and extracting nucleic acids from biological samples
AU2015296029B2 (en) 2014-08-01 2022-01-27 Dovetail Genomics, Llc Tagging nucleic acids for sequence assembly
BR122021026779B1 (pt) 2014-10-17 2023-12-19 Illumina Cambridge Limited Transposon de preservação de contiguidade
US9771412B2 (en) 2014-10-31 2017-09-26 Wisconsin Alumni Research Foundation Engineered intein for improved production of protein-intein fusions
WO2016126747A1 (en) * 2015-02-02 2016-08-11 Meiragtx Uk Limited Regulation of gene expression by aptamer-mediated modulation of alternative splicing
ES3062422T3 (en) 2015-02-10 2026-04-10 Illumina Inc Compositions for analyzing cellular components
WO2016138496A1 (en) 2015-02-27 2016-09-01 Cellular Research, Inc. Spatially addressable molecular barcoding
US20180284125A1 (en) 2015-03-11 2018-10-04 The Broad Institute, Inc. Proteomic analysis with nucleic acid identifiers
WO2016164530A1 (en) 2015-04-07 2016-10-13 University Of Maryland, College Park Compositions and methods for high throughput protein sequencing
CA2988771A1 (en) 2015-06-09 2016-12-15 The Board Of Regents Of The University Of Texas System Diagnostic test for early stage cancer
CN108779460B (zh) * 2015-12-07 2023-08-01 睿恩达思技术公司 在分配中使用微粒的多路技术
US11286517B2 (en) 2016-02-17 2022-03-29 President And Fellows Of Harvard College Molecular programming tools
KR102516168B1 (ko) 2016-05-02 2023-03-30 엔코디아, 인코포레이티드 암호화 핵산을 사용한 거대분자 분석
EP4108781A1 (en) 2016-05-27 2022-12-28 President and Fellows of Harvard College Conditional primer extension for single-molecule detection
WO2018005720A1 (en) 2016-06-30 2018-01-04 President And Fellows Of Harvard College Method of determining the molecular binding between libraries of molecules
FR3054039B1 (fr) * 2016-07-12 2020-05-29 Universite De Montpellier Biocapteur pour detecter la presence de bacteries
CN109790574A (zh) 2016-07-22 2019-05-21 哈佛学院院长及董事 用于蛋白质鉴别的方法和组合物
GB201616313D0 (en) * 2016-09-26 2016-11-09 Oslo Universitetssykehus Hf And Universitetet I Oslo Method
EP4310183B1 (en) 2017-01-30 2025-07-09 10X Genomics, Inc. Methods and systems for droplet-based single cell barcoding
DK3583214T5 (da) 2017-02-02 2024-09-02 New York Genome Center Inc Fremgangsmåder og sammensætninger til identificering eller kvantificering af mål i en biologisk prøve
US11072816B2 (en) * 2017-05-03 2021-07-27 The Broad Institute, Inc. Single-cell proteomic assay using aptamers
WO2019089846A1 (en) 2017-10-31 2019-05-09 Encodia, Inc. Methods and compositions for polypeptide analysis
MX2020004559A (es) 2017-10-31 2020-10-05 Encodia Inc Kits para análisis utilizando codificación y/o etiqueta de ácido nucleico.
US20210355483A1 (en) 2017-10-31 2021-11-18 Encodia, Inc. Methods and kits using nucleic acid encoding and/or label
CA3086915A1 (en) 2017-12-29 2019-07-04 Sujal M. Patel Decoding approaches for protein identification
EP3740567A4 (en) 2018-01-18 2022-03-09 Nanosomix Inc. DETECTION OF EXOSOMES AND EXOSOMAL BIOMARKERS FOR DIAGNOSIS AND PROGNOSIS OF DISEASES AND DISORDERS
US12270741B2 (en) 2018-04-03 2025-04-08 Tymora Analytical Operations, Llc Methods for affinity-based non-antibody capture and purification of extracellular vesicles
CN112236528A (zh) * 2018-04-04 2021-01-15 诺迪勒思生物科技公司 产生纳米阵列和微阵列的方法
EP4242324B1 (en) * 2018-08-17 2025-09-24 Becton, Dickinson and Company Aptamer barcoding
US11549135B2 (en) * 2018-09-14 2023-01-10 The Broad Institute, Inc. Oligonucleotide-coupled antibodies for single cell or single complex protein measurements
US11078480B2 (en) * 2018-09-19 2021-08-03 California Institute Of Technology High-throughput identification of intermolecular interactions
EP3963070A4 (en) 2019-04-30 2023-02-22 Encodia, Inc. METHODS OF PREPARATION OF ANALYTES AND RELATED KITS

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