JP2022529344A5 - - Google Patents
Info
- Publication number
- JP2022529344A5 JP2022529344A5 JP2021561633A JP2021561633A JP2022529344A5 JP 2022529344 A5 JP2022529344 A5 JP 2022529344A5 JP 2021561633 A JP2021561633 A JP 2021561633A JP 2021561633 A JP2021561633 A JP 2021561633A JP 2022529344 A5 JP2022529344 A5 JP 2022529344A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- sequence
- amino acid
- chain variable
- variable region
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP19170207 | 2019-04-18 | ||
| EP19170207.5 | 2019-04-18 | ||
| EP19207105 | 2019-11-05 | ||
| EP19207105.8 | 2019-11-05 | ||
| EP20165055.3 | 2020-03-23 | ||
| EP20165055 | 2020-03-23 | ||
| PCT/EP2020/060898 WO2020212593A1 (en) | 2019-04-18 | 2020-04-17 | Novel molecules for therapy and diagnosis |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022529344A JP2022529344A (ja) | 2022-06-21 |
| JP2022529344A5 true JP2022529344A5 (https=) | 2023-04-24 |
| JP7689373B2 JP7689373B2 (ja) | 2025-06-06 |
Family
ID=70285703
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021561633A Active JP7689373B2 (ja) | 2019-04-18 | 2020-04-17 | 治療及び診断のための新規分子 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US12534519B2 (https=) |
| EP (1) | EP3956027A1 (https=) |
| JP (1) | JP7689373B2 (https=) |
| KR (1) | KR20210154179A (https=) |
| CN (2) | CN121873233A (https=) |
| AU (1) | AU2020258025A1 (https=) |
| CA (1) | CA3133909A1 (https=) |
| MX (1) | MX2021012608A (https=) |
| TW (1) | TW202104255A (https=) |
| WO (1) | WO2020212593A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3051839A1 (en) | 2017-02-17 | 2018-08-23 | Bristol-Myers Squibb Company | Antibodies to alpha-synuclein and uses thereof |
| JPWO2022265091A1 (https=) * | 2021-06-18 | 2022-12-22 | ||
| CN113912714B (zh) * | 2021-12-15 | 2022-02-22 | 北京凯祥弘康生物科技有限公司 | 特异性结合α-突触核蛋白的抗体及其应用 |
| CN113912712B (zh) * | 2021-12-15 | 2022-03-08 | 北京凯祥弘康生物科技有限公司 | 抗α-突触核蛋白的单克隆抗体的制备及其应用 |
| KR20240176098A (ko) * | 2023-06-14 | 2024-12-24 | 경상국립대학교산학협력단 | 알파 시누클레인 에피토프를 유효성분으로 포함하는 파킨슨병의 예방 또는 치료용 조성물 |
| WO2025093720A1 (en) | 2023-11-02 | 2025-05-08 | Betasense Gmbh | Methods for determining misfolded alpha-synuclein in a sample |
| WO2025134068A1 (en) | 2023-12-22 | 2025-06-26 | Ac Immune Sa | Antibody drug conjugates targeting proteinopathies, and uses thereof |
| WO2025158162A1 (en) * | 2024-01-25 | 2025-07-31 | Imperial College Innovations Limited | Alpha-synuclein antibody |
| CN120064410A (zh) * | 2025-04-28 | 2025-05-30 | 协和生物制药（天津）有限公司 | 一种用于α-突触核蛋白检测的电化学生物传感器 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| GB8607679D0 (en) | 1986-03-27 | 1986-04-30 | Winter G P | Recombinant dna product |
| IL85035A0 (en) | 1987-01-08 | 1988-06-30 | Int Genetic Eng | Polynucleotide molecule,a chimeric antibody with specificity for human b cell surface antigen,a process for the preparation and methods utilizing the same |
| JP3101690B2 (ja) | 1987-03-18 | 2000-10-23 | エス・ビィ・２・インコーポレイテッド | 変性抗体の、または変性抗体に関する改良 |
| FR2707189B1 (fr) | 1993-07-09 | 1995-10-13 | Gradient Ass | Procédé de traitement de résidus de combustion et installation de mise en Óoeuvre dudit procédé. |
| DE69535243T2 (de) | 1994-07-13 | 2007-05-10 | Chugai Seiyaku K.K. | Gegen menschliches interleukin-8 gerichteter, rekonstituierter menschlicher antikörper |
| DK1069185T3 (da) | 1998-04-03 | 2011-06-27 | Chugai Pharmaceutical Co Ltd | Humaniseret antistof mod human vævsfaktor (TF) og fremgangsmåde til at konstruere humaniseret antistof |
| US6737056B1 (en) | 1999-01-15 | 2004-05-18 | Genentech, Inc. | Polypeptide variants with altered effector function |
| PL209392B1 (pl) | 1999-01-15 | 2011-08-31 | Genentech Inc | Przeciwciało, komórka gospodarza, sposób wytwarzania przeciwciała oraz zastosowanie przeciwciała |
| EP1332209B1 (en) | 2000-09-08 | 2009-11-11 | Universität Zürich | Collections of repeat proteins comprising repeat modules |
| EP2141243A3 (en) | 2000-10-16 | 2010-01-27 | Brystol-Myers Squibb Company | Protein scaffolds for antibody mimics and other binding proteins |
| US20030157561A1 (en) | 2001-11-19 | 2003-08-21 | Kolkman Joost A. | Combinatorial libraries of monomer domains |
| TWI335821B (en) | 2002-12-16 | 2011-01-11 | Genentech Inc | Immunoglobulin variants and uses thereof |
| US20050147989A1 (en) * | 2003-10-02 | 2005-07-07 | Uwe Bertsch | Screening assay for aggregations |
| US20050164301A1 (en) | 2003-10-24 | 2005-07-28 | Avidia Research Institute | LDL receptor class A and EGF domain monomers and multimers |
| JP6027011B2 (ja) | 2010-10-26 | 2016-11-16 | エーシー イミューン ソシエテ アノニム | 疎水性部分によって修飾されたペプチドを含むリポソームベースの構築物 |
| JP6325463B2 (ja) | 2012-03-16 | 2018-05-16 | コヴァジェン アクチェン ゲゼルシャフト | 抗腫瘍活性を有する新規結合分子 |
| GB201512203D0 (en) * | 2015-07-13 | 2015-08-19 | Lundbeck & Co As H | Agents,uses and methods |
| US10160800B2 (en) | 2016-06-02 | 2018-12-25 | Medimmune Limited | Antibodies to α-synuclein and uses thereof |
| BR112018014281A2 (pt) * | 2016-11-15 | 2018-12-18 | H Lundbeck As | agentes, usos e métodos para o tratamento da sinucleinopatia |
| EP3555127B1 (en) * | 2016-12-16 | 2024-12-18 | H. Lundbeck A/S | Agents, uses and methods |
| US11155608B2 (en) * | 2017-08-23 | 2021-10-26 | The Trustees Of The University Of Pennsylvania | Monoclonal antibodies against pathological alpha-synuclein, and methods using same |
-
2020
- 2020-04-17 JP JP2021561633A patent/JP7689373B2/ja active Active
- 2020-04-17 CA CA3133909A patent/CA3133909A1/en active Pending
- 2020-04-17 WO PCT/EP2020/060898 patent/WO2020212593A1/en not_active Ceased
- 2020-04-17 KR KR1020217036474A patent/KR20210154179A/ko active Pending
- 2020-04-17 CN CN202511931795.2A patent/CN121873233A/zh active Pending
- 2020-04-17 US US17/603,513 patent/US12534519B2/en active Active
- 2020-04-17 AU AU2020258025A patent/AU2020258025A1/en active Pending
- 2020-04-17 MX MX2021012608A patent/MX2021012608A/es unknown
- 2020-04-17 CN CN202080044911.8A patent/CN114206444B/zh active Active
- 2020-04-17 EP EP20718677.6A patent/EP3956027A1/en active Pending
- 2020-04-20 TW TW109113222A patent/TW202104255A/zh unknown
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