JP2022529008A - 長期安定な生存糞便微生物叢組成物 - Google Patents

長期安定な生存糞便微生物叢組成物 Download PDF

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Publication number
JP2022529008A
JP2022529008A JP2021561644A JP2021561644A JP2022529008A JP 2022529008 A JP2022529008 A JP 2022529008A JP 2021561644 A JP2021561644 A JP 2021561644A JP 2021561644 A JP2021561644 A JP 2021561644A JP 2022529008 A JP2022529008 A JP 2022529008A
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Prior art keywords
water
composition
absorbing
excipients
composition according
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JP2021561644A
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Japanese (ja)
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JP2022529008A5 (https=
Inventor
ホセップ・エメ・スニェ・ネグレ
アレックス・ソリアーノ・ビラドミウ
アンドレア・アイラ・ゴメス
クサバ・フェヘール
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Universitat de Barcelona UB
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Universitat de Barcelona UB
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Publication of JP2022529008A publication Critical patent/JP2022529008A/ja
Publication of JP2022529008A5 publication Critical patent/JP2022529008A5/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/485—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4875—Compounds of unknown constitution, e.g. material from plants or animals

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Botany (AREA)
  • Zoology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2021561644A 2019-04-15 2020-04-14 長期安定な生存糞便微生物叢組成物 Pending JP2022529008A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP19382287 2019-04-15
EP19382287.1 2019-04-15
PCT/EP2020/060370 WO2020212297A1 (en) 2019-04-15 2020-04-14 Long-term stable live fecal microbiota composition

Publications (2)

Publication Number Publication Date
JP2022529008A true JP2022529008A (ja) 2022-06-16
JP2022529008A5 JP2022529008A5 (https=) 2023-04-25

Family

ID=66349477

Family Applications (1)

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JP2021561644A Pending JP2022529008A (ja) 2019-04-15 2020-04-14 長期安定な生存糞便微生物叢組成物

Country Status (19)

Country Link
US (2) US20220143107A1 (https=)
EP (2) EP3955899B1 (https=)
JP (1) JP2022529008A (https=)
KR (1) KR20210152505A (https=)
CN (1) CN113710237B (https=)
AU (1) AU2020259740B2 (https=)
BR (1) BR112021020606A2 (https=)
CA (1) CA3130816A1 (https=)
DK (1) DK3955899T3 (https=)
EA (1) EA202192291A1 (https=)
ES (1) ES3035981T3 (https=)
FI (1) FI3955899T3 (https=)
IL (1) IL287238A (https=)
MX (1) MX2021011246A (https=)
PH (1) PH12021552573A1 (https=)
PL (1) PL3955899T3 (https=)
PT (1) PT3955899T (https=)
SG (1) SG11202110641XA (https=)
WO (1) WO2020212297A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112017024265B1 (pt) 2015-05-11 2022-08-09 Mybiotics Pharma Ltd Métodos para crescimento de um biofilme de bactérias probióticas em partículas sólidas
IL294171A (en) 2016-05-25 2022-08-01 Mybiotics Pharma Ltd Composition and methods for microbiota therapy
EP3955899B1 (en) 2019-04-15 2025-05-07 Fundació de Recerca Clínic Barcelona-Institut d'Investigacions Biomèdiques August Pi i Sunyer (FRCB-IDIBAPS) Long-term stable live microbiota composition

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0636692A1 (fr) * 1993-07-29 1995-02-01 LESAFFRE et Cie Biomasse stable à base de cellules de levure et de bactéries lactiques et procédé de préparation
JP2004538311A (ja) * 2001-07-27 2004-12-24 サノフィ−サンテラボ オーティーシー エス．ピー．エー． バチルス属の非病原性細菌の胞子を含む固体組成物
JP2007508035A (ja) * 2003-11-07 2007-04-05 ザ　プロクター　アンド　ギャンブル　カンパニー プロバイオティクス菌を含む安定化された組成物
WO2009096908A2 (en) * 2008-01-30 2009-08-06 Sevgi Takka Extended-release fluvastatin tablet
WO2018002331A1 (en) * 2016-06-30 2018-01-04 Firmenich Sa Plated yeast formulations
WO2019043051A1 (en) * 2017-08-29 2019-03-07 Chr. Hansen A/S STABLE CAPSULES COMPRISING A FECAL MICROBIOTE OR A CULTURE OF MICROORGANISMS

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1190386A (en) * 1966-06-28 1970-05-06 Green Cross Corp Process for producing the Lactic Acid Bacteria Drugs
US20050266069A1 (en) 2002-09-06 2005-12-01 Simmons Donald L Stable probiotic microsphere compositions and their methods of preparation
GB0330009D0 (en) * 2003-12-24 2004-01-28 Ferrosan As Probiotic tablet formulations
CA2623968C (en) 2005-09-29 2014-12-09 Merck Patent Gesellschaft Mit Beschraenkter Haftung Method for stabilising pharmaceutical administration forms comprising microorganisms
DE102005062731A1 (de) * 2005-12-22 2007-06-28 Organobalance Gmbh Neue Lactobacillus Stämme und deren Verwendung
CA2808610C (en) * 2010-08-10 2018-09-25 R.P. Scherer Technologies, Llc Process of manufacturing a stable softgel capsule containing microencapsulated probiotic bacteria
CN104095180A (zh) * 2013-04-12 2014-10-15 中国科学院烟台海岸带研究所 一种益生菌菊粉片及其制备方法
US10583420B2 (en) * 2014-10-01 2020-03-10 7905122 Canada Inc. Process and apparatus for manufacturing water-absorbing material and use in cat litter
WO2016178775A1 (en) * 2015-05-01 2016-11-10 Microbiome Health Research Institute Inc. Compositions and methods for therapeutic delivery of microbial communities
CN104922158B (zh) * 2015-06-05 2018-11-02 中国人民解放军第三军医大学第三附属医院 粪菌胶囊及其制备与应用
US10905726B2 (en) 2015-06-09 2021-02-02 Rebiotix, Inc. Microbiota restoration therapy (MRT) compositions and methods of manufacture
US20200147151A1 (en) * 2017-01-30 2020-05-14 The Board Of Regents Of The University Of Texas System Compositions and methods for fecal microbiota transplantation
CN108567799A (zh) * 2018-08-01 2018-09-25 中国人民解放军总医院 一种全粪菌复合胶囊及其制备方法和应用
EP3955899B1 (en) 2019-04-15 2025-05-07 Fundació de Recerca Clínic Barcelona-Institut d'Investigacions Biomèdiques August Pi i Sunyer (FRCB-IDIBAPS) Long-term stable live microbiota composition

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0636692A1 (fr) * 1993-07-29 1995-02-01 LESAFFRE et Cie Biomasse stable à base de cellules de levure et de bactéries lactiques et procédé de préparation
JP2004538311A (ja) * 2001-07-27 2004-12-24 サノフィ−サンテラボ オーティーシー エス．ピー．エー． バチルス属の非病原性細菌の胞子を含む固体組成物
JP2007508035A (ja) * 2003-11-07 2007-04-05 ザ　プロクター　アンド　ギャンブル　カンパニー プロバイオティクス菌を含む安定化された組成物
WO2009096908A2 (en) * 2008-01-30 2009-08-06 Sevgi Takka Extended-release fluvastatin tablet
WO2018002331A1 (en) * 2016-06-30 2018-01-04 Firmenich Sa Plated yeast formulations
WO2019043051A1 (en) * 2017-08-29 2019-03-07 Chr. Hansen A/S STABLE CAPSULES COMPRISING A FECAL MICROBIOTE OR A CULTURE OF MICROORGANISMS

Also Published As

Publication number Publication date
KR20210152505A (ko) 2021-12-15
EP4609873A2 (en) 2025-09-03
EP3955899B1 (en) 2025-05-07
PT3955899T (pt) 2025-07-18
EA202192291A1 (ru) 2022-02-11
DK3955899T3 (da) 2025-08-04
BR112021020606A2 (pt) 2021-12-07
AU2020259740B2 (en) 2025-12-18
AU2020259740A1 (en) 2021-10-28
MX2021011246A (es) 2022-01-18
IL287238A (en) 2021-12-01
SG11202110641XA (en) 2021-10-28
EP4609873A3 (en) 2025-11-12
CN113710237A (zh) 2021-11-26
CN113710237B (zh) 2026-04-03
WO2020212297A1 (en) 2020-10-22
EP3955899A1 (en) 2022-02-23
PH12021552573A1 (en) 2022-07-04
US20240131085A1 (en) 2024-04-25
FI3955899T3 (fi) 2025-07-28
US12521422B2 (en) 2026-01-13
PL3955899T3 (pl) 2025-09-22
CA3130816A1 (en) 2020-10-22
ES3035981T3 (en) 2025-09-11
US20220143107A1 (en) 2022-05-12

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