AU2020259740B2 - Long-term stable live fecal microbiota composition - Google Patents

Long-term stable live fecal microbiota composition

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Publication number
AU2020259740B2
AU2020259740B2 AU2020259740A AU2020259740A AU2020259740B2 AU 2020259740 B2 AU2020259740 B2 AU 2020259740B2 AU 2020259740 A AU2020259740 A AU 2020259740A AU 2020259740 A AU2020259740 A AU 2020259740A AU 2020259740 B2 AU2020259740 B2 AU 2020259740B2
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AU
Australia
Prior art keywords
water absorbing
composition according
composition
excipient
fecal microbiota
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
AU2020259740A
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English (en)
Other versions
AU2020259740A1 (en
Inventor
Andrea AIRA GOMEZ
Csaba Feher
Alex SORIANO VILADOMIU
Josep M. SUÑÉ NEGRE
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universitat de Barcelona UB
Hospital Clinic de Barcelona
Institut d'Investigacions Biomèdiques August Pi i Sunyer
Original Assignee
Universitat de Barcelona UB
Hospital Clinic de Barcelona
Institut d'Investigacions Biomèdiques August Pi i Sunyer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by Universitat de Barcelona UB, Hospital Clinic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer filed Critical Universitat de Barcelona UB
Publication of AU2020259740A1 publication Critical patent/AU2020259740A1/en
Application granted granted Critical
Publication of AU2020259740B2 publication Critical patent/AU2020259740B2/en
Assigned to UNIVERSITAT DE BARCELONA, HOSPITAL CLÍNIC DE BARCELONA, Fundació de Recerca Clínic Barcelona Institut d’Investigacions Biomèdiques August Pi i Sunyer reassignment UNIVERSITAT DE BARCELONA Request for Assignment Assignors: FUNDACIÓ CLÍNIC PER A LA RECERCA BIOMÈDICA, HOSPITAL CLÍNIC DE BARCELONA, INSTITUT D'INVESTIGACIONS BIOMÈDIQUES AUGUST PI I SUNYER (IDIBAPS), UNIVERSITAT DE BARCELONA
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/485—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4875—Compounds of unknown constitution, e.g. material from plants or animals

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Botany (AREA)
  • Zoology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AU2020259740A 2019-04-15 2020-04-14 Long-term stable live fecal microbiota composition Active AU2020259740B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP19382287 2019-04-15
EP19382287.1 2019-04-15
PCT/EP2020/060370 WO2020212297A1 (en) 2019-04-15 2020-04-14 Long-term stable live fecal microbiota composition

Publications (2)

Publication Number Publication Date
AU2020259740A1 AU2020259740A1 (en) 2021-10-28
AU2020259740B2 true AU2020259740B2 (en) 2025-12-18

Family

ID=66349477

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2020259740A Active AU2020259740B2 (en) 2019-04-15 2020-04-14 Long-term stable live fecal microbiota composition

Country Status (19)

Country Link
US (2) US20220143107A1 (https=)
EP (2) EP3955899B1 (https=)
JP (1) JP2022529008A (https=)
KR (1) KR20210152505A (https=)
CN (1) CN113710237B (https=)
AU (1) AU2020259740B2 (https=)
BR (1) BR112021020606A2 (https=)
CA (1) CA3130816A1 (https=)
DK (1) DK3955899T3 (https=)
EA (1) EA202192291A1 (https=)
ES (1) ES3035981T3 (https=)
FI (1) FI3955899T3 (https=)
IL (1) IL287238A (https=)
MX (1) MX2021011246A (https=)
PH (1) PH12021552573A1 (https=)
PL (1) PL3955899T3 (https=)
PT (1) PT3955899T (https=)
SG (1) SG11202110641XA (https=)
WO (1) WO2020212297A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112017024265B1 (pt) 2015-05-11 2022-08-09 Mybiotics Pharma Ltd Métodos para crescimento de um biofilme de bactérias probióticas em partículas sólidas
IL294171A (en) 2016-05-25 2022-08-01 Mybiotics Pharma Ltd Composition and methods for microbiota therapy
EP3955899B1 (en) 2019-04-15 2025-05-07 Fundació de Recerca Clínic Barcelona-Institut d'Investigacions Biomèdiques August Pi i Sunyer (FRCB-IDIBAPS) Long-term stable live microbiota composition

Citations (7)

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Publication number Priority date Publication date Assignee Title
GB1190386A (en) * 1966-06-28 1970-05-06 Green Cross Corp Process for producing the Lactic Acid Bacteria Drugs
JP2007508035A (ja) * 2003-11-07 2007-04-05 ザ　プロクター　アンド　ギャンブル　カンパニー プロバイオティクス菌を含む安定化された組成物
US20120039998A1 (en) * 2010-08-10 2012-02-16 R.P. Scherer Technologies, Llc Process of manufacturing a stable softgel capsule containing microencapsulated probiotic bacteria
CN104922158A (zh) * 2015-06-05 2015-09-23 中国人民解放军第三军医大学第三附属医院 粪菌胶囊及其制备与应用
WO2016178775A1 (en) * 2015-05-01 2016-11-10 Microbiome Health Research Institute Inc. Compositions and methods for therapeutic delivery of microbial communities
CN108567799A (zh) * 2018-08-01 2018-09-25 中国人民解放军总医院 一种全粪菌复合胶囊及其制备方法和应用
WO2019043051A1 (en) * 2017-08-29 2019-03-07 Chr. Hansen A/S STABLE CAPSULES COMPRISING A FECAL MICROBIOTE OR A CULTURE OF MICROORGANISMS

Family Cites Families (13)

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FR2708621B1 (fr) * 1993-07-29 1995-10-20 Lesaffre & Cie Biomasse stable à base de cellules de levure et de bactéries lactiques et procédé de préparation.
ITMI20011632A1 (it) 2001-07-27 2003-01-27 Sanofi Synthelabo Composizione solida contenente spore di batteri non patogeni del genere bacillus
US20050266069A1 (en) 2002-09-06 2005-12-01 Simmons Donald L Stable probiotic microsphere compositions and their methods of preparation
GB0330009D0 (en) * 2003-12-24 2004-01-28 Ferrosan As Probiotic tablet formulations
CA2623968C (en) 2005-09-29 2014-12-09 Merck Patent Gesellschaft Mit Beschraenkter Haftung Method for stabilising pharmaceutical administration forms comprising microorganisms
DE102005062731A1 (de) * 2005-12-22 2007-06-28 Organobalance Gmbh Neue Lactobacillus Stämme und deren Verwendung
TR200800634A2 (tr) * 2008-01-30 2009-02-23 Takka Sevgi̇ Uzatılmış salım sağlayan fluvastatin tablet.
CN104095180A (zh) * 2013-04-12 2014-10-15 中国科学院烟台海岸带研究所 一种益生菌菊粉片及其制备方法
US10583420B2 (en) * 2014-10-01 2020-03-10 7905122 Canada Inc. Process and apparatus for manufacturing water-absorbing material and use in cat litter
US10905726B2 (en) 2015-06-09 2021-02-02 Rebiotix, Inc. Microbiota restoration therapy (MRT) compositions and methods of manufacture
CN109414048B (zh) * 2016-06-30 2023-09-01 弗门尼舍有限公司 包衣酵母配方
US20200147151A1 (en) * 2017-01-30 2020-05-14 The Board Of Regents Of The University Of Texas System Compositions and methods for fecal microbiota transplantation
EP3955899B1 (en) 2019-04-15 2025-05-07 Fundació de Recerca Clínic Barcelona-Institut d'Investigacions Biomèdiques August Pi i Sunyer (FRCB-IDIBAPS) Long-term stable live microbiota composition

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1190386A (en) * 1966-06-28 1970-05-06 Green Cross Corp Process for producing the Lactic Acid Bacteria Drugs
JP2007508035A (ja) * 2003-11-07 2007-04-05 ザ　プロクター　アンド　ギャンブル　カンパニー プロバイオティクス菌を含む安定化された組成物
US20120039998A1 (en) * 2010-08-10 2012-02-16 R.P. Scherer Technologies, Llc Process of manufacturing a stable softgel capsule containing microencapsulated probiotic bacteria
WO2016178775A1 (en) * 2015-05-01 2016-11-10 Microbiome Health Research Institute Inc. Compositions and methods for therapeutic delivery of microbial communities
CN104922158A (zh) * 2015-06-05 2015-09-23 中国人民解放军第三军医大学第三附属医院 粪菌胶囊及其制备与应用
WO2019043051A1 (en) * 2017-08-29 2019-03-07 Chr. Hansen A/S STABLE CAPSULES COMPRISING A FECAL MICROBIOTE OR A CULTURE OF MICROORGANISMS
CN108567799A (zh) * 2018-08-01 2018-09-25 中国人民解放军总医院 一种全粪菌复合胶囊及其制备方法和应用

Also Published As

Publication number Publication date
KR20210152505A (ko) 2021-12-15
EP4609873A2 (en) 2025-09-03
EP3955899B1 (en) 2025-05-07
PT3955899T (pt) 2025-07-18
EA202192291A1 (ru) 2022-02-11
DK3955899T3 (da) 2025-08-04
BR112021020606A2 (pt) 2021-12-07
AU2020259740A1 (en) 2021-10-28
MX2021011246A (es) 2022-01-18
IL287238A (en) 2021-12-01
SG11202110641XA (en) 2021-10-28
JP2022529008A (ja) 2022-06-16
EP4609873A3 (en) 2025-11-12
CN113710237A (zh) 2021-11-26
CN113710237B (zh) 2026-04-03
WO2020212297A1 (en) 2020-10-22
EP3955899A1 (en) 2022-02-23
PH12021552573A1 (en) 2022-07-04
US20240131085A1 (en) 2024-04-25
FI3955899T3 (fi) 2025-07-28
US12521422B2 (en) 2026-01-13
PL3955899T3 (pl) 2025-09-22
CA3130816A1 (en) 2020-10-22
ES3035981T3 (en) 2025-09-11
US20220143107A1 (en) 2022-05-12

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Legal Events

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Owner name: FUNDACIO DE RECERCA CLINIC BARCELONA INSTITUT D'INVESTIGACIONS BIOMEDIQUES AUGUST PI I SUNYER

Free format text: FORMER APPLICANT(S): INSTITUT D'INVESTIGACIONS BIOMEDIQUES AUGUST PI I SUNYER (IDIBAPS); FUNDACIO CLINIC PER A LA RECERCA BIOMEDICA; HOSPITAL CLINIC DE BARCELONA; UNIVERSITAT DE BARCELONA

Owner name: HOSPITAL CLINIC DE BARCELONA

Free format text: FORMER APPLICANT(S): INSTITUT D'INVESTIGACIONS BIOMEDIQUES AUGUST PI I SUNYER (IDIBAPS); FUNDACIO CLINIC PER A LA RECERCA BIOMEDICA; HOSPITAL CLINIC DE BARCELONA; UNIVERSITAT DE BARCELONA

Owner name: UNIVERSITAT DE BARCELONA

Free format text: FORMER APPLICANT(S): INSTITUT D'INVESTIGACIONS BIOMEDIQUES AUGUST PI I SUNYER (IDIBAPS); FUNDACIO CLINIC PER A LA RECERCA BIOMEDICA; HOSPITAL CLINIC DE BARCELONA; UNIVERSITAT DE BARCELONA

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