KR20210152505A - 장기간 안정하게 살아있는 대변 미생물총 조성물 - Google Patents

장기간 안정하게 살아있는 대변 미생물총 조성물 Download PDF

Info

Publication number
KR20210152505A
KR20210152505A KR1020217036103A KR20217036103A KR20210152505A KR 20210152505 A KR20210152505 A KR 20210152505A KR 1020217036103 A KR1020217036103 A KR 1020217036103A KR 20217036103 A KR20217036103 A KR 20217036103A KR 20210152505 A KR20210152505 A KR 20210152505A
Authority
KR
South Korea
Prior art keywords
composition
excipient
provided above
fecal
optionally
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
KR1020217036103A
Other languages
English (en)
Korean (ko)
Inventor
조셉 엠. 수네 네그레
알렉스 소리아노 빌라도미우
안드레아 아이라 고메즈
사바 페헤르
Original Assignee
인스티튜트 디＇인베스티가시온스 바이오메디퀘스 아우구스트 피 아이 수니에르
펀다시오 클리닉 퍼 아 라 레세르카 비오메디카
호스피탈 크리닉 드 바르셀로나
유니버시테이트 드 바르셀로나
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 인스티튜트 디＇인베스티가시온스 바이오메디퀘스 아우구스트 피 아이 수니에르, 펀다시오 클리닉 퍼 아 라 레세르카 비오메디카, 호스피탈 크리닉 드 바르셀로나, 유니버시테이트 드 바르셀로나 filed Critical 인스티튜트 디＇인베스티가시온스 바이오메디퀘스 아우구스트 피 아이 수니에르
Publication of KR20210152505A publication Critical patent/KR20210152505A/ko
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/485—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4875—Compounds of unknown constitution, e.g. material from plants or animals

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Botany (AREA)
  • Zoology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
KR1020217036103A 2019-04-15 2020-04-14 장기간 안정하게 살아있는 대변 미생물총 조성물 Pending KR20210152505A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP19382287 2019-04-15
EP19382287.1 2019-04-15
PCT/EP2020/060370 WO2020212297A1 (en) 2019-04-15 2020-04-14 Long-term stable live fecal microbiota composition

Publications (1)

Publication Number Publication Date
KR20210152505A true KR20210152505A (ko) 2021-12-15

Family

ID=66349477

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020217036103A Pending KR20210152505A (ko) 2019-04-15 2020-04-14 장기간 안정하게 살아있는 대변 미생물총 조성물

Country Status (19)

Country Link
US (2) US20220143107A1 (https=)
EP (2) EP3955899B1 (https=)
JP (1) JP2022529008A (https=)
KR (1) KR20210152505A (https=)
CN (1) CN113710237B (https=)
AU (1) AU2020259740B2 (https=)
BR (1) BR112021020606A2 (https=)
CA (1) CA3130816A1 (https=)
DK (1) DK3955899T3 (https=)
EA (1) EA202192291A1 (https=)
ES (1) ES3035981T3 (https=)
FI (1) FI3955899T3 (https=)
IL (1) IL287238A (https=)
MX (1) MX2021011246A (https=)
PH (1) PH12021552573A1 (https=)
PL (1) PL3955899T3 (https=)
PT (1) PT3955899T (https=)
SG (1) SG11202110641XA (https=)
WO (1) WO2020212297A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112017024265B1 (pt) 2015-05-11 2022-08-09 Mybiotics Pharma Ltd Métodos para crescimento de um biofilme de bactérias probióticas em partículas sólidas
IL294171A (en) 2016-05-25 2022-08-01 Mybiotics Pharma Ltd Composition and methods for microbiota therapy
EP3955899B1 (en) 2019-04-15 2025-05-07 Fundació de Recerca Clínic Barcelona-Institut d'Investigacions Biomèdiques August Pi i Sunyer (FRCB-IDIBAPS) Long-term stable live microbiota composition

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1190386A (en) * 1966-06-28 1970-05-06 Green Cross Corp Process for producing the Lactic Acid Bacteria Drugs
FR2708621B1 (fr) * 1993-07-29 1995-10-20 Lesaffre & Cie Biomasse stable à base de cellules de levure et de bactéries lactiques et procédé de préparation.
ITMI20011632A1 (it) 2001-07-27 2003-01-27 Sanofi Synthelabo Composizione solida contenente spore di batteri non patogeni del genere bacillus
US20050266069A1 (en) 2002-09-06 2005-12-01 Simmons Donald L Stable probiotic microsphere compositions and their methods of preparation
US20050100559A1 (en) * 2003-11-07 2005-05-12 The Procter & Gamble Company Stabilized compositions comprising a probiotic
GB0330009D0 (en) * 2003-12-24 2004-01-28 Ferrosan As Probiotic tablet formulations
CA2623968C (en) 2005-09-29 2014-12-09 Merck Patent Gesellschaft Mit Beschraenkter Haftung Method for stabilising pharmaceutical administration forms comprising microorganisms
DE102005062731A1 (de) * 2005-12-22 2007-06-28 Organobalance Gmbh Neue Lactobacillus Stämme und deren Verwendung
TR200800634A2 (tr) * 2008-01-30 2009-02-23 Takka Sevgi̇ Uzatılmış salım sağlayan fluvastatin tablet.
CA2808610C (en) * 2010-08-10 2018-09-25 R.P. Scherer Technologies, Llc Process of manufacturing a stable softgel capsule containing microencapsulated probiotic bacteria
CN104095180A (zh) * 2013-04-12 2014-10-15 中国科学院烟台海岸带研究所 一种益生菌菊粉片及其制备方法
US10583420B2 (en) * 2014-10-01 2020-03-10 7905122 Canada Inc. Process and apparatus for manufacturing water-absorbing material and use in cat litter
WO2016178775A1 (en) * 2015-05-01 2016-11-10 Microbiome Health Research Institute Inc. Compositions and methods for therapeutic delivery of microbial communities
CN104922158B (zh) * 2015-06-05 2018-11-02 中国人民解放军第三军医大学第三附属医院 粪菌胶囊及其制备与应用
US10905726B2 (en) 2015-06-09 2021-02-02 Rebiotix, Inc. Microbiota restoration therapy (MRT) compositions and methods of manufacture
CN109414048B (zh) * 2016-06-30 2023-09-01 弗门尼舍有限公司 包衣酵母配方
US20200147151A1 (en) * 2017-01-30 2020-05-14 The Board Of Regents Of The University Of Texas System Compositions and methods for fecal microbiota transplantation
US20200188310A1 (en) 2017-08-29 2020-06-18 Chr. Hansen A/S Stable capsules with fecal microbiota or a culture of microorganisms
CN108567799A (zh) * 2018-08-01 2018-09-25 中国人民解放军总医院 一种全粪菌复合胶囊及其制备方法和应用
EP3955899B1 (en) 2019-04-15 2025-05-07 Fundació de Recerca Clínic Barcelona-Institut d'Investigacions Biomèdiques August Pi i Sunyer (FRCB-IDIBAPS) Long-term stable live microbiota composition

Also Published As

Publication number Publication date
EP4609873A2 (en) 2025-09-03
EP3955899B1 (en) 2025-05-07
PT3955899T (pt) 2025-07-18
EA202192291A1 (ru) 2022-02-11
DK3955899T3 (da) 2025-08-04
BR112021020606A2 (pt) 2021-12-07
AU2020259740B2 (en) 2025-12-18
AU2020259740A1 (en) 2021-10-28
MX2021011246A (es) 2022-01-18
IL287238A (en) 2021-12-01
SG11202110641XA (en) 2021-10-28
JP2022529008A (ja) 2022-06-16
EP4609873A3 (en) 2025-11-12
CN113710237A (zh) 2021-11-26
CN113710237B (zh) 2026-04-03
WO2020212297A1 (en) 2020-10-22
EP3955899A1 (en) 2022-02-23
PH12021552573A1 (en) 2022-07-04
US20240131085A1 (en) 2024-04-25
FI3955899T3 (fi) 2025-07-28
US12521422B2 (en) 2026-01-13
PL3955899T3 (pl) 2025-09-22
CA3130816A1 (en) 2020-10-22
ES3035981T3 (en) 2025-09-11
US20220143107A1 (en) 2022-05-12

Similar Documents

Publication Publication Date Title
US12521422B2 (en) Long-term stable live fecal microbiota composition
AU2016252209B2 (en) Method of preparing a faecal microbiota sample
US12186349B2 (en) Compositions and methods for C. difficile treatment
CA3007289C (fr) Procede de lyophilisation d'un echantillon de microbiote fecal
EP3389681B1 (fr) Composition lyophilisee pour la conservation de microbiote dans son ecosysteme
CA3029635A1 (en) Compositions and methods for c. difficile treatment
WO2019043051A1 (en) STABLE CAPSULES COMPRISING A FECAL MICROBIOTE OR A CULTURE OF MICROORGANISMS
EP2243487A1 (en) Enteric coated formulation
AU2018212530B2 (en) Fecal microbiota for treating patients undergoing a hematopoietic stem cell transplant
EP4552700A3 (en) Intervention strategy for prevention or treatment of diabetes mellitus, autoimmune disease, inflammatory disease or cardiovascular disease
HK40068341A (en) Long‑term stable live microbiota composition
HK40068341B (en) Long‑term stable live microbiota composition
EP3758723A1 (en) Methods for prognosing and treating metabolic diseases
Ai et al. Dual-functional natural drug-loaded responsive hydrogel for activating autophagy and regulating immune microenvironment in the treatment of diabetic periodontitis
KR102820861B1 (ko) 유산균 저장 안정성 증강용 조성물 및 이를 이용한 저장 안정성 개선방법
US20260108552A1 (en) Uses of Dendrobium polysaccharides and vancomycin-sensitive bacteria, and compositions containing the same
JP3991026B2 (ja) 胃炎、胃・十二指腸潰瘍の予防及び治療剤
JPS6320804B2 (https=)
CN120459053A (zh) 一种用于治疗幽门螺杆菌感染并逆转胃肠化生的载纳米胶囊原位凝胶及其应用
Shahaboddin 1-Department of Clinical Biochemistry, Faculty of Medicine, Kashan University of Medical Sciences, Kashan, Iran. 2-Infectious Disease Research Center, Kashan University of Medical Sciences, Kashan, Iran. 3-Department of Microbiology, Faculty of Medicine, Kashan University of Medical Sciences, Kashan, Iran. 4-Institute of Nanoscience and Nanotechnology, University of Kashan, Kashan, Iran. 5-Gametogenesis Research Center, Kashan University of Medical Sciences, Kashan, Iran.
JP2004075694A (ja) 抗ヘリコバクター・ピロリ活性剤

Legal Events

Date Code Title Description
PA0105 International application

St.27 status event code: A-0-1-A10-A15-nap-PA0105

PG1501 Laying open of application

St.27 status event code: A-1-1-Q10-Q12-nap-PG1501

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

PA0201 Request for examination

St.27 status event code: A-1-2-D10-D11-exm-PA0201

R18-X000 Changes to party contact information recorded

St.27 status event code: A-3-3-R10-R18-oth-X000

D21 Rejection of application intended

Free format text: ST27 STATUS EVENT CODE: A-1-2-D10-D21-EXM-PE0902 (AS PROVIDED BY THE NATIONAL OFFICE)

PE0902 Notice of grounds for rejection

St.27 status event code: A-1-2-D10-D21-exm-PE0902

R17 Change to representative recorded

Free format text: ST27 STATUS EVENT CODE: A-3-3-R10-R17-OTH-X000 (AS PROVIDED BY THE NATIONAL OFFICE)

R17-X000 Change to representative recorded

St.27 status event code: A-3-3-R10-R17-oth-X000

T11 Administrative time limit extension requested

Free format text: ST27 STATUS EVENT CODE: U-3-3-T10-T11-OTH-X000 (AS PROVIDED BY THE NATIONAL OFFICE)

T11-X000 Administrative time limit extension requested

St.27 status event code: U-3-3-T10-T11-oth-X000

T11 Administrative time limit extension requested

Free format text: ST27 STATUS EVENT CODE: U-3-3-T10-T11-OTH-X000 (AS PROVIDED BY THE NATIONAL OFFICE)

T11-X000 Administrative time limit extension requested

St.27 status event code: U-3-3-T10-T11-oth-X000

E13 Pre-grant limitation requested

Free format text: ST27 STATUS EVENT CODE: A-2-3-E10-E13-LIM-X000 (AS PROVIDED BY THE NATIONAL OFFICE)

E13-X000 Pre-grant limitation requested

St.27 status event code: A-2-3-E10-E13-lim-X000

P11 Amendment of application requested

Free format text: ST27 STATUS EVENT CODE: A-2-2-P10-P11-NAP-X000 (AS PROVIDED BY THE NATIONAL OFFICE)

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000