JP2022527709A5 - - Google Patents
Info
- Publication number
- JP2022527709A5 JP2022527709A5 JP2021557392A JP2021557392A JP2022527709A5 JP 2022527709 A5 JP2022527709 A5 JP 2022527709A5 JP 2021557392 A JP2021557392 A JP 2021557392A JP 2021557392 A JP2021557392 A JP 2021557392A JP 2022527709 A5 JP2022527709 A5 JP 2022527709A5
- Authority
- JP
- Japan
- Prior art keywords
- cells
- plasmid
- transgene
- aav
- crispr
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025106768A JP2025160172A (ja) | 2019-03-27 | 2025-06-24 | Ｃａｓ９／ｒｎｐおよびａａｖウイルスの組み合わせを使用したがん免疫療法のための、キメラ抗原受容体（ｃａｒ）－初代ｎｋ細胞の生成 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962825007P | 2019-03-27 | 2019-03-27 | |
| US62/825,007 | 2019-03-27 | ||
| PCT/US2020/025454 WO2020198675A1 (en) | 2019-03-27 | 2020-03-27 | Generation of chimeric antigen receptor (car)-primary nk cells for cancer immunotherapy using a combination of cas9/rnp and aav viruses |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025106768A Division JP2025160172A (ja) | 2019-03-27 | 2025-06-24 | Ｃａｓ９／ｒｎｐおよびａａｖウイルスの組み合わせを使用したがん免疫療法のための、キメラ抗原受容体（ｃａｒ）－初代ｎｋ細胞の生成 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022527709A JP2022527709A (ja) | 2022-06-03 |
| JP2022527709A5 true JP2022527709A5 (enExample) | 2023-03-31 |
| JP7702878B2 JP7702878B2 (ja) | 2025-07-04 |
Family
ID=72611833
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021557392A Active JP7702878B2 (ja) | 2019-03-27 | 2020-03-27 | Ｃａｓ９／ｒｎｐおよびａａｖウイルスの組み合わせを使用したがん免疫療法のための、キメラ抗原受容体（ｃａｒ）－初代ｎｋ細胞の生成 |
| JP2025106768A Pending JP2025160172A (ja) | 2019-03-27 | 2025-06-24 | Ｃａｓ９／ｒｎｐおよびａａｖウイルスの組み合わせを使用したがん免疫療法のための、キメラ抗原受容体（ｃａｒ）－初代ｎｋ細胞の生成 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025106768A Pending JP2025160172A (ja) | 2019-03-27 | 2025-06-24 | Ｃａｓ９／ｒｎｐおよびａａｖウイルスの組み合わせを使用したがん免疫療法のための、キメラ抗原受容体（ｃａｒ）－初代ｎｋ細胞の生成 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US12655449B2 (enExample) |
| EP (1) | EP3946432A4 (enExample) |
| JP (2) | JP7702878B2 (enExample) |
| KR (1) | KR20220017887A (enExample) |
| CN (1) | CN113891727A (enExample) |
| AU (1) | AU2020248097B2 (enExample) |
| BR (1) | BR112021019180A2 (enExample) |
| CA (1) | CA3135198A1 (enExample) |
| CO (1) | CO2021014353A2 (enExample) |
| IL (1) | IL286701A (enExample) |
| MX (1) | MX2021011782A (enExample) |
| PH (1) | PH12021552383A1 (enExample) |
| SG (1) | SG11202110613SA (enExample) |
| WO (1) | WO2020198675A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019165121A1 (en) | 2018-02-21 | 2019-08-29 | Board Of Regents, The University Of Texas System | Methods for activation and expansion of natural killer cells and uses therof |
| AU2021372458A1 (en) * | 2020-10-26 | 2023-06-15 | Research Institute At Nationwide Children's Hospital | Chimeric antigen receptor (car) nk cells and uses thereof |
| WO2022236174A1 (en) * | 2021-05-07 | 2022-11-10 | Washington University | In situ car-t therapies, vectors and methods therefor |
| CN117716024A (zh) * | 2021-06-01 | 2024-03-15 | 瓦克斯细胞生物 | 包含饲养细胞的自然杀伤细胞增殖用组合物 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUE051612T2 (hu) * | 2012-07-11 | 2021-03-01 | Sangamo Therapeutics Inc | Eljárások és készítmények lizoszomális tárolási betegségek kezelésére |
| CN111206032B (zh) | 2013-12-12 | 2024-07-19 | 布罗德研究所有限公司 | 用于基因组编辑的crispr-cas系统和组合物的递送、用途和治疗应用 |
| BR112017000939A2 (pt) | 2014-07-21 | 2017-11-14 | Novartis Ag | tratamento de câncer usando um receptor antigênico quimérico de cll-1 |
| EP3204496A1 (en) | 2014-10-10 | 2017-08-16 | Editas Medicine, Inc. | Compositions and methods for promoting homology directed repair |
| PL3298134T3 (pl) | 2015-05-16 | 2023-09-18 | Genzyme Corporation | Edycja genów mutacji głęboko intronowych |
| US11911415B2 (en) * | 2015-06-09 | 2024-02-27 | Editas Medicine, Inc. | CRISPR/Cas-related methods and compositions for improving transplantation |
| WO2017093804A2 (en) | 2015-12-01 | 2017-06-08 | Crispr Therapeutics Ag | Materials and methods for treatment of alpha-1 antitrypsin deficiency |
| CN110267978A (zh) | 2016-10-07 | 2019-09-20 | 得克萨斯大学体系董事会 | 用于治疗癌症的表达膜锚定的il-12的t细胞 |
| EP3532075A4 (en) | 2016-10-27 | 2020-07-08 | Intima Bioscience, Inc. | VIRAL METHODS OF MANUFACTURING GENETICALLY MODIFIED CELLS |
| JP2020518245A (ja) | 2017-05-03 | 2020-06-25 | サンガモ セラピューティクス， インコーポレイテッド | 嚢胞性線維症膜貫通コンダクタンス制御因子（ｃｆｔｒ）遺伝子の改変のための方法および組成物 |
| EP4775669A2 (en) * | 2017-06-30 | 2026-07-15 | Precision Biosciences, Inc. | Genetically-modified t cells comprising a modified intron in the t cell receptor alpha gene |
| SG11202007288VA (en) | 2018-01-30 | 2020-08-28 | Res Institute At Nationwide Children’S Hospital | Transforming growth factor beta-resistant natural killer cells |
| CN108504685A (zh) * | 2018-03-27 | 2018-09-07 | 宜明细胞生物科技有限公司 | 一种利用CRISPR/Cas9系统同源重组修复IL-2RG缺陷基因的方法 |
| AU2019271366B2 (en) | 2018-05-16 | 2026-02-26 | Research Institute At Nationwide Children's Hospital | Generation of knock-out primary and expanded human NK cells using Cas9 ribonucleoproteins |
-
2020
- 2020-03-27 MX MX2021011782A patent/MX2021011782A/es unknown
- 2020-03-27 AU AU2020248097A patent/AU2020248097B2/en active Active
- 2020-03-27 BR BR112021019180A patent/BR112021019180A2/pt unknown
- 2020-03-27 JP JP2021557392A patent/JP7702878B2/ja active Active
- 2020-03-27 KR KR1020217034800A patent/KR20220017887A/ko active Pending
- 2020-03-27 CN CN202080036500.4A patent/CN113891727A/zh active Pending
- 2020-03-27 PH PH1/2021/552383A patent/PH12021552383A1/en unknown
- 2020-03-27 WO PCT/US2020/025454 patent/WO2020198675A1/en not_active Ceased
- 2020-03-27 US US17/598,619 patent/US12655449B2/en active Active
- 2020-03-27 CA CA3135198A patent/CA3135198A1/en active Pending
- 2020-03-27 EP EP20777892.9A patent/EP3946432A4/en active Pending
- 2020-03-27 SG SG11202110613SA patent/SG11202110613SA/en unknown
-
2021
- 2021-09-26 IL IL286701A patent/IL286701A/en unknown
- 2021-10-26 CO CONC2021/0014353A patent/CO2021014353A2/es unknown
-
2025
- 2025-06-24 JP JP2025106768A patent/JP2025160172A/ja active Pending
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