JP2022527630A - 鎌状赤血球症を治療するためのｐｄｅ９阻害剤 - Google Patents

鎌状赤血球症を治療するためのｐｄｅ９阻害剤 Download PDF

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JP2022527630A
JP2022527630A JP2021560228A JP2021560228A JP2022527630A JP 2022527630 A JP2022527630 A JP 2022527630A JP 2021560228 A JP2021560228 A JP 2021560228A JP 2021560228 A JP2021560228 A JP 2021560228A JP 2022527630 A JP2022527630 A JP 2022527630A
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スベンストルップ，ニールス
ペトロシャン，ヴァニク
ティシ，デイヴィッド
ワーシントン，ジェフリー
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イマラ インク．
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JP2021560228A 2019-04-05 2020-04-03 鎌状赤血球症を治療するためのｐｄｅ９阻害剤 Pending JP2022527630A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962829784P 2019-04-05 2019-04-05
US62/829,784 2019-04-05
PCT/US2020/026696 WO2020206336A1 (en) 2019-04-05 2020-04-03 Pde9 inhibitors for treating sickle cell disease

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JP2022527630A true JP2022527630A (ja) 2022-06-02
JP2022527630A5 JP2022527630A5 (https=) 2023-04-10

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US (1) US20220023302A1 (https=)
EP (1) EP3946348A4 (https=)
JP (1) JP2022527630A (https=)
CN (1) CN114302724A (https=)
BR (1) BR112021019876A2 (https=)
CA (1) CA3136128A1 (https=)
IL (1) IL286976A (https=)
WO (1) WO2020206336A1 (https=)
ZA (1) ZA202107544B (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT3865484T (pt) 2015-07-07 2024-01-30 H Lundbeck As Inibidor da pde9 com esqueleto de imidazo pirazinona para tratamento de doenças periféricas
CA3100988A1 (en) 2018-05-25 2019-11-28 Imara Inc. Monohydrate and crystalline forms of 6-[(3s,4s)-4-methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl]-3-tetrahydropyran-4-yl-7h-imidazo[1,5-a]pyrazin-8-one
CA3110680A1 (en) 2018-08-31 2020-03-05 Imara Inc. Pde9 inhibitors for treating sickle cell disease

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008260708A (ja) * 2007-04-11 2008-10-30 Ohkura Pharmaceutical Co Ltd ベンズイソキサゾール誘導体の経口ゼリー状医薬組成物
JP5341282B1 (ja) * 2012-06-29 2013-11-13 丸石製薬株式会社 アリピプラゾールの経口医薬製剤
WO2018009424A1 (en) * 2016-07-06 2018-01-11 Imara, Inc. Pde9 inhibitors for treatment of peripheral diseases
US20180133222A1 (en) * 2016-04-04 2018-05-17 Loxo Oncology, Inc. Methods of treating pediatric cancers
WO2018218104A1 (en) * 2017-05-26 2018-11-29 Imara, Inc. Methods of making and using pde9 inhibitors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009507032A (ja) * 2005-09-02 2009-02-19 アボット・ラボラトリーズ 新規なイミダゾ系複素環
BR112015007731B1 (pt) * 2011-10-10 2022-05-31 H. Lundbeck A/S Composto, composição farmacêutica que o compreende e uso do mesmo
PT3865484T (pt) * 2015-07-07 2024-01-30 H Lundbeck As Inibidor da pde9 com esqueleto de imidazo pirazinona para tratamento de doenças periféricas
EP3965768A1 (en) * 2019-05-07 2022-03-16 Imara Inc. Pde9 inhibitors for treating thalassemia

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008260708A (ja) * 2007-04-11 2008-10-30 Ohkura Pharmaceutical Co Ltd ベンズイソキサゾール誘導体の経口ゼリー状医薬組成物
JP5341282B1 (ja) * 2012-06-29 2013-11-13 丸石製薬株式会社 アリピプラゾールの経口医薬製剤
US20180133222A1 (en) * 2016-04-04 2018-05-17 Loxo Oncology, Inc. Methods of treating pediatric cancers
WO2018009424A1 (en) * 2016-07-06 2018-01-11 Imara, Inc. Pde9 inhibitors for treatment of peripheral diseases
WO2018218104A1 (en) * 2017-05-26 2018-11-29 Imara, Inc. Methods of making and using pde9 inhibitors

Also Published As

Publication number Publication date
WO2020206336A1 (en) 2020-10-08
ZA202107544B (en) 2022-08-31
BR112021019876A2 (pt) 2022-01-18
IL286976A (en) 2021-12-01
CN114302724A (zh) 2022-04-08
CA3136128A1 (en) 2020-10-08
US20220023302A1 (en) 2022-01-27
EP3946348A4 (en) 2023-08-02
EP3946348A1 (en) 2022-02-09

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