JP2022525651A - Ｃｄ４欠損ｃａｒ ｔ細胞および抗ｃｄ４ ｃａｒ ｔ細胞を作製するための方法および組成物ならびにその使用 - Google Patents

Ｃｄ４欠損ｃａｒ ｔ細胞および抗ｃｄ４ ｃａｒ ｔ細胞を作製するための方法および組成物ならびにその使用 Download PDF

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JP2022525651A
JP2022525651A JP2021556400A JP2021556400A JP2022525651A JP 2022525651 A JP2022525651 A JP 2022525651A JP 2021556400 A JP2021556400 A JP 2021556400A JP 2021556400 A JP2021556400 A JP 2021556400A JP 2022525651 A JP2022525651 A JP 2022525651A
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cell
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car
hiv
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ワグナー，ソー
サーニ，ジャヤ
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シアトル チルドレンズ ホスピタル （ディービーエイ シアトル チルドレンズ リサーチ インスティテュート）
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JP2021556400A 2019-03-19 2020-03-17 Ｃｄ４欠損ｃａｒ ｔ細胞および抗ｃｄ４ ｃａｒ ｔ細胞を作製するための方法および組成物ならびにその使用 Pending JP2022525651A (ja)

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JP2024163218A JP2024175115A (ja) 2019-03-19 2024-09-20 Ｃｄ４欠損ｃａｒ ｔ細胞および抗ｃｄ４ ｃａｒ ｔ細胞を作製するための方法および組成物ならびにその使用

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US201962820387P 2019-03-19 2019-03-19
US62/820,387 2019-03-19
PCT/US2020/023117 WO2020190925A1 (en) 2019-03-19 2020-03-17 Methods and compositions for engineering cd4-deficient car t cells and anti-cd4 car t cells and uses thereof

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JP2024163218A Pending JP2024175115A (ja) 2019-03-19 2024-09-20 Ｃｄ４欠損ｃａｒ ｔ細胞および抗ｃｄ４ ｃａｒ ｔ細胞を作製するための方法および組成物ならびにその使用

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EP4458378A4 (en) * 2021-12-30 2025-07-09 Chongqing Prec Biotech Co Ltd TECHNIQUE FOR PREPARING A UNIVERSAL CAR-T CELL, AND APPLICATION OF A UNIVERSAL CAR-T CELL
CN116410932A (zh) * 2021-12-30 2023-07-11 重庆精准生物技术有限公司 一种通用型car-t细胞的制备方法及其应用
CN116410931A (zh) * 2021-12-30 2023-07-11 重庆精准生物技术有限公司 一种通用型car-t细胞的制备技术及其应用
WO2026032970A1 (en) * 2024-08-07 2026-02-12 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Cd4-specific chimeric antigen receptor and methods and uses thereof

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JP2018513692A (ja) * 2015-02-27 2018-05-31 アイセル・ジーン・セラピューティクス・エルエルシー 血液系腫瘍を標的としたキメラ抗体受容体（ＣＡＲｓ）の構成およびその使用方法

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US6710169B2 (en) * 1987-10-02 2004-03-23 Genentech, Inc. Adheson variants
WO2019106522A1 (en) * 2017-11-28 2019-06-06 Novartis Ag Pooled crispr/cas9 screening in primary cells using guide swap technology

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JP2018513692A (ja) * 2015-02-27 2018-05-31 アイセル・ジーン・セラピューティクス・エルエルシー 血液系腫瘍を標的としたキメラ抗体受容体（ＣＡＲｓ）の構成およびその使用方法
WO2017044776A1 (en) * 2015-09-10 2017-03-16 Texas Tech University System Single-guide rna (sgrna) with improved knockout efficiency

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SARAFOVA SD. ET AL.: "Deletion of the highly conserved functionalregion of the Cd4 enhancer NCE in RLM11cells using CRISPR", J IMMUNOL, vol. 200 (1_Supplement): 165.12., JPN6024003009, 2018, ISSN: 0005439709 *

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JP2024175115A (ja) 2024-12-17
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WO2020190925A1 (en) 2020-09-24
US20220054549A1 (en) 2022-02-24

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