|
US5688787A
(en)
|
1991-07-23 |
1997-11-18 |
Schering Corporation |
Substituted β-lactam compounds useful as hypochlesterolemic agents and processes for the preparation thereof
|
|
US5631356A
(en)
|
1992-04-03 |
1997-05-20 |
Gist-Brocades, N.V. |
Selective N-acylation of amino alcohols
|
|
LT3595B
(en)
|
1993-01-21 |
1995-12-27 |
Schering Corp |
Spirocycloalkyl-substituted azetidinones useful as hypocholesterolemic agents
|
|
US5631365A
(en)
|
1993-09-21 |
1997-05-20 |
Schering Corporation |
Hydroxy-substituted azetidinone compounds useful as hypocholesterolemic agents
|
|
FR2710337B1
(fr)
|
1993-09-23 |
1995-12-08 |
Gerard Coquerel |
Procédé de dédoublement de deux antipodes optiques par entraînement polythermique programmé et autoensemencé.
|
|
US5633246A
(en)
|
1994-11-18 |
1997-05-27 |
Schering Corporation |
Sulfur-substituted azetidinone compounds useful as hypocholesterolemic agents
|
|
US5624920A
(en)
|
1994-11-18 |
1997-04-29 |
Schering Corporation |
Sulfur-substituted azetidinone compounds useful as hypocholesterolemic agents
|
|
US5656624A
(en)
|
1994-12-21 |
1997-08-12 |
Schering Corporation |
4-[(heterocycloalkyl or heteroaromatic)-substituted phenyl]-2-azetidinones useful as hypolipidemic agents
|
|
US5756470A
(en)
|
1996-10-29 |
1998-05-26 |
Schering Corporation |
Sugar-substituted 2-azetidinones useful as hypocholesterolemic agents
|
|
US6602710B1
(en)
|
1998-08-27 |
2003-08-05 |
Chugai Seiyaku Kabushiki Kaisha |
Screening method for SREBP pathway-specific inhibitors
|
|
GB9916757D0
(en)
|
1999-07-17 |
1999-09-15 |
Glaxo Group Ltd |
Method
|
|
HRP20030498A2
(en)
|
2000-12-21 |
2005-04-30 |
Aventis Pharma Deutschland Gmbh |
Novel 1,2-diphenzylazetidinones, method for producing the same, medicaments containing said compounds, and the use thereof for treating disorders of the lipid metabolism
|
|
TWI291957B
(en)
|
2001-02-23 |
2008-01-01 |
Kotobuki Pharmaceutical Co Ltd |
Beta-lactam compounds, process for repoducing the same and serum cholesterol-lowering agents containing the same
|
|
US20080249040A1
(en)
|
2001-05-18 |
2008-10-09 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of sterol regulatory element binding protein 1 (SREBP1) gene expression using short interfering nucleic acid (siNA)
|
|
AU2002320621A1
(en)
|
2001-07-20 |
2003-03-03 |
Incyte Genomics, Inc. |
Structural and cytoskeleton-associated proteins
|
|
WO2003033656A2
(en)
*
|
2001-10-16 |
2003-04-24 |
Exelixis, Inc. |
MSREBPs AS MODIFIERS OF THE SREBP PATHWAY AND METHODS OF USE
|
|
US20050014177A1
(en)
|
2003-05-19 |
2005-01-20 |
Koustubh Ranade |
Human sterol response element binding protein 1 (SREBP1) single nucleotide polymorphisms
|
|
AU2007275365A1
(en)
*
|
2006-07-17 |
2008-01-24 |
Sirna Therapeutics Inc. |
RNA interference mediated inhibition of Proprotein Convertase Subtilisin Kexin 9 (PCSK9) gene expression using short interfering nucleic acid (siNA)
|
|
AU2007297388A1
(en)
|
2006-09-18 |
2008-03-27 |
Alnylam Pharmaceuticals, Inc. |
RNAi modulation of scap and therapeutic uses thereof
|
|
JP2010053122A
(ja)
*
|
2008-07-31 |
2010-03-11 |
Hayashibara Biochem Lab Inc |
脂質合成阻害剤
|
|
US9187746B2
(en)
|
2009-09-22 |
2015-11-17 |
Alnylam Pharmaceuticals, Inc. |
Dual targeting siRNA agents
|
|
WO2011087857A2
(en)
*
|
2009-12-22 |
2011-07-21 |
The Administrators Of The Tulane Educational Fund |
Compositions and methods for treating obesity and diabetes
|
|
WO2015100257A1
(en)
|
2013-12-23 |
2015-07-02 |
The General Hospital Corporation |
Methods and assays for determining reduced brca1 pathway function in a cancer cell
|
|
WO2017100542A1
(en)
|
2015-12-10 |
2017-06-15 |
Alnylam Pharmaceuticals, Inc. |
Sterol regulatory element binding protein (srebp) chaperone (scap) irna compositions and methods of use thereof
|
|
CN105441454B
(zh)
|
2015-12-23 |
2018-12-11 |
北京大学人民医院 |
Scap基因突变体及其应用
|
|
MX2018013499A
(es)
|
2016-05-03 |
2019-09-11 |
Lonza Ag |
Modulacion del metabolismo lipidico para la produccion de proteinas.
|
|
WO2019141723A1
(en)
*
|
2018-01-18 |
2019-07-25 |
Roche Innovation Center Copenhagen A/S |
Antisense oligonucleotides targeting srebp1
|
|
AU2019212959A1
(en)
|
2018-01-29 |
2020-09-17 |
Capulus Therapeutics, Llc |
SREBP inhibitors comprising a 6-membered central ring
|
|
US11648260B2
(en)
|
2018-03-29 |
2023-05-16 |
Technion Research And Development Foundation Limitted |
Vesicles comprising a PTEN inhibitor and uses of same
|
|
CN109536610B
(zh)
*
|
2018-12-05 |
2020-10-16 |
西南大学 |
Setdb1在调控胆固醇途径中的应用
|