JP2022523055A5 - - Google Patents
Info
- Publication number
- JP2022523055A5 JP2022523055A5 JP2021543277A JP2021543277A JP2022523055A5 JP 2022523055 A5 JP2022523055 A5 JP 2022523055A5 JP 2021543277 A JP2021543277 A JP 2021543277A JP 2021543277 A JP2021543277 A JP 2021543277A JP 2022523055 A5 JP2022523055 A5 JP 2022523055A5
- Authority
- JP
- Japan
- Prior art keywords
- item
- crispr
- polynucleotide according
- sequence
- polynucleotide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962797122P | 2019-01-25 | 2019-01-25 | |
| US62/797,122 | 2019-01-25 | ||
| US201962876177P | 2019-07-19 | 2019-07-19 | |
| US62/876,177 | 2019-07-19 | ||
| US201962939553P | 2019-11-22 | 2019-11-22 | |
| US62/939,553 | 2019-11-22 | ||
| PCT/US2020/015127 WO2020154714A2 (en) | 2019-01-25 | 2020-01-25 | Systems and methods for modulating crispr activity |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022523055A JP2022523055A (ja) | 2022-04-21 |
| JP2022523055A5 true JP2022523055A5 (https=) | 2023-02-02 |
Family
ID=71735803
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021543277A Pending JP2022523055A (ja) | 2019-01-25 | 2020-01-25 | Ｃｒｉｓｐｒ活性をモジュレートするための系および方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US11884918B2 (https=) |
| EP (1) | EP3914714A4 (https=) |
| JP (1) | JP2022523055A (https=) |
| KR (1) | KR20210123309A (https=) |
| CN (1) | CN113874503A (https=) |
| AU (1) | AU2020210884A1 (https=) |
| CA (1) | CA3127486A1 (https=) |
| GB (1) | GB2597377A (https=) |
| WO (1) | WO2020154714A2 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20210045360A (ko) | 2018-05-16 | 2021-04-26 | 신테고 코포레이션 | 가이드 rna 설계 및 사용을 위한 방법 및 시스템 |
| EP3823633A4 (en) | 2018-06-29 | 2023-05-03 | Editas Medicine, Inc. | SYNTHETIC LEAD MOLECULES, COMPOSITIONS AND METHODS RELATED THERETO |
| US20220411790A1 (en) * | 2019-10-25 | 2022-12-29 | The Johns Hopkins University | A crispr-cas9 platform with an intrinsic off-switch and enhanced specificity |
| US20240200059A1 (en) * | 2021-04-09 | 2024-06-20 | Vor Biopharma Inc. | Photocleavable guide rnas and methods of use thereof |
| CN114410752B (zh) * | 2022-01-24 | 2024-06-25 | 华南师范大学 | 一种基于光控的CRISPR-Cas核酸检测试剂盒及检测方法 |
| US20260103702A1 (en) * | 2022-09-30 | 2026-04-16 | Board Of Trustees Of Southern Illinois University | Compositions and methods for crispr modulation |
| WO2024215715A2 (en) * | 2023-04-11 | 2024-10-17 | President And Fellows Of Harvard College | Chemical ligation techniques |
Family Cites Families (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5795587A (en) | 1995-01-23 | 1998-08-18 | University Of Pittsburgh | Stable lipid-comprising drug delivery complexes and methods for their production |
| US5849902A (en) | 1996-09-26 | 1998-12-15 | Oligos Etc. Inc. | Three component chimeric antisense oligonucleotides |
| US20090181858A1 (en) * | 2004-09-21 | 2009-07-16 | The Scripps Research Institute | Adding photoregulated amino acids to the genetic code |
| BRPI0617191A2 (pt) * | 2005-10-12 | 2011-07-19 | Scripps Research Inst | modificação pós-traducional de polipeptìdeos expressos em fagos |
| US8158595B2 (en) | 2006-11-09 | 2012-04-17 | California Institute Of Technology | Modular aptamer-regulated ribozymes |
| US9371348B2 (en) | 2006-11-27 | 2016-06-21 | The Trustees Of The University Of Pennsylvania | Photocleavable oligonucleotide and uses thereof |
| US7897737B2 (en) | 2006-12-05 | 2011-03-01 | Lasergen, Inc. | 3′-OH unblocked, nucleotides and nucleosides, base modified with photocleavable, terminating groups and methods for their use in DNA sequencing |
| CA2689042A1 (en) | 2007-02-16 | 2008-08-28 | Merck & Co., Inc. | Compositions and methods for potentiated activity of biologicaly active molecules |
| US7923562B2 (en) | 2008-06-16 | 2011-04-12 | The Board Of Trustees Of The Leland Stanford Junior University | Photocleavable linker methods and compositions |
| JP2011525180A (ja) | 2008-06-16 | 2011-09-15 | バインド バイオサイエンシズ インコーポレイテッド | 治療的標的化ナノ粒子の製作に用いるためのジブロックコポリマーで官能化された標的薬の製造方法 |
| US20100087337A1 (en) | 2008-09-10 | 2010-04-08 | Bind Biosciences, Inc. | High Throughput Fabrication of Nanoparticles |
| JP2012512175A (ja) | 2008-12-15 | 2012-05-31 | バインド バイオサイエンシズ インコーポレイテッド | 治療薬を徐放するための長時間循環性ナノ粒子 |
| BRPI1012036A2 (pt) | 2009-05-27 | 2017-10-10 | Selecta Biosciences Inc | nanocarreadores que possuem componentes com diferentes taxas de liberação |
| EA201290497A1 (ru) | 2009-12-15 | 2013-01-30 | Байнд Байосайенсиз, Инк. | Терапевтические полимерные наночастицы, включающие кортикостероиды, и способы получения таковых |
| WO2011107747A2 (en) * | 2010-03-05 | 2011-09-09 | Medical Research Council | Genetically encoded photocontrol |
| US20130037977A1 (en) | 2010-04-08 | 2013-02-14 | Paul A. Burke | Preparation of Lipid Nanoparticles |
| US20120171229A1 (en) | 2010-12-30 | 2012-07-05 | Selecta Biosciences, Inc. | Synthetic nanocarriers with reactive groups that release biologically active agents |
| CA2824526C (en) | 2011-01-11 | 2020-07-07 | Alnylam Pharmaceuticals, Inc. | Pegylated lipids and their use for drug delivery |
| WO2013065827A1 (ja) * | 2011-11-04 | 2013-05-10 | 国立大学法人埼玉大学 | 核酸リンカー |
| US9228207B2 (en) * | 2013-09-06 | 2016-01-05 | President And Fellows Of Harvard College | Switchable gRNAs comprising aptamers |
| US10093929B2 (en) * | 2013-10-14 | 2018-10-09 | Stc.Unm | Modular RNA regulators and methods |
| US20150376586A1 (en) * | 2014-06-25 | 2015-12-31 | Caribou Biosciences, Inc. | RNA Modification to Engineer Cas9 Activity |
| WO2016022866A1 (en) | 2014-08-07 | 2016-02-11 | Agilent Technologies, Inc. | Cis-blocked guide rna |
| US9816080B2 (en) * | 2014-10-31 | 2017-11-14 | President And Fellows Of Harvard College | Delivery of CAS9 via ARRDC1-mediated microvesicles (ARMMs) |
| WO2016094874A1 (en) * | 2014-12-12 | 2016-06-16 | The Broad Institute Inc. | Escorted and functionalized guides for crispr-cas systems |
| US9650617B2 (en) * | 2015-01-28 | 2017-05-16 | Pioneer Hi-Bred International. Inc. | CRISPR hybrid DNA/RNA polynucleotides and methods of use |
| JP2018515142A (ja) * | 2015-05-15 | 2018-06-14 | ダーマコン，インコーポレイテッド． | Ｃａｓ９介在遺伝子編集用の合成シングルガイドｒｎａ |
| EP3353309A4 (en) * | 2015-09-25 | 2019-04-10 | Tarveda Therapeutics, Inc. | COMPOSITIONS AND METHOD FOR GENERIC EDITING |
| CN109072224B (zh) * | 2016-01-30 | 2022-07-15 | 株式会社博纳克 | 人工单导rna及其用途 |
| US20200291369A1 (en) | 2016-03-11 | 2020-09-17 | Erasmus University Medical Center Rotterdam | Improved CRISPR-Cas9 Genome Editing Tool |
| EP3219799A1 (en) * | 2016-03-17 | 2017-09-20 | IMBA-Institut für Molekulare Biotechnologie GmbH | Conditional crispr sgrna expression |
| CN109415729B (zh) | 2016-04-21 | 2022-12-09 | 生命技术公司 | 具有降低毒性的基因编辑试剂 |
| WO2017217768A1 (ko) * | 2016-06-15 | 2017-12-21 | 주식회사 툴젠 | 온타겟 및 오프타겟의 다중 타겟 시스템을 이용하는, 표적 특이적 유전자 가위 스크리닝 방법 및 이의 용도 |
| EP3638789A4 (en) * | 2017-06-12 | 2021-03-10 | California Institute of Technology | CONDITIONAL GUIDE RNAS |
-
2020
- 2020-01-25 CN CN202080024105.4A patent/CN113874503A/zh active Pending
- 2020-01-25 GB GB2110534.1A patent/GB2597377A/en not_active Withdrawn
- 2020-01-25 KR KR1020217023538A patent/KR20210123309A/ko not_active Abandoned
- 2020-01-25 JP JP2021543277A patent/JP2022523055A/ja active Pending
- 2020-01-25 AU AU2020210884A patent/AU2020210884A1/en not_active Abandoned
- 2020-01-25 WO PCT/US2020/015127 patent/WO2020154714A2/en not_active Ceased
- 2020-01-25 CA CA3127486A patent/CA3127486A1/en active Pending
- 2020-01-25 EP EP20744712.9A patent/EP3914714A4/en active Pending
-
2021
- 2021-07-23 US US17/384,328 patent/US11884918B2/en active Active
-
2023
- 2023-12-07 US US18/532,892 patent/US20240209356A1/en active Pending
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