JP2022521877A5 - - Google Patents

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Publication number
JP2022521877A5
JP2022521877A5 JP2021534224A JP2021534224A JP2022521877A5 JP 2022521877 A5 JP2022521877 A5 JP 2022521877A5 JP 2021534224 A JP2021534224 A JP 2021534224A JP 2021534224 A JP2021534224 A JP 2021534224A JP 2022521877 A5 JP2022521877 A5 JP 2022521877A5
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JP
Japan
Application number
JP2021534224A
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Japanese (ja)
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JPWO2020123083A5 (https=
JP2022521877A (ja
JP7535047B2 (ja
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Priority claimed from PCT/US2019/061241 external-priority patent/WO2020123083A1/en
Publication of JP2022521877A publication Critical patent/JP2022521877A/ja
Publication of JPWO2020123083A5 publication Critical patent/JPWO2020123083A5/ja
Publication of JP2022521877A5 publication Critical patent/JP2022521877A5/ja
Priority to JP2024070175A priority Critical patent/JP7748500B2/ja
Application granted granted Critical
Publication of JP7535047B2 publication Critical patent/JP7535047B2/ja
Active legal-status Critical Current
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JP2021534224A 2018-12-12 2019-11-13 トリループを含む二本鎖核酸インヒビター分子 Active JP7535047B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024070175A JP7748500B2 (ja) 2018-12-12 2024-04-24 トリループを含む二本鎖核酸インヒビター分子

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862778759P 2018-12-12 2018-12-12
US62/778,759 2018-12-12
PCT/US2019/061241 WO2020123083A1 (en) 2018-12-12 2019-11-13 Double-stranded nucleic acid inhibitor molecules containing a triloop

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2024070175A Division JP7748500B2 (ja) 2018-12-12 2024-04-24 トリループを含む二本鎖核酸インヒビター分子

Publications (4)

Publication Number Publication Date
JP2022521877A JP2022521877A (ja) 2022-04-13
JPWO2020123083A5 JPWO2020123083A5 (https=) 2022-11-24
JP2022521877A5 true JP2022521877A5 (https=) 2022-11-24
JP7535047B2 JP7535047B2 (ja) 2024-08-15

Family

ID=71076672

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021534224A Active JP7535047B2 (ja) 2018-12-12 2019-11-13 トリループを含む二本鎖核酸インヒビター分子
JP2024070175A Active JP7748500B2 (ja) 2018-12-12 2024-04-24 トリループを含む二本鎖核酸インヒビター分子

Family Applications After (1)

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JP2024070175A Active JP7748500B2 (ja) 2018-12-12 2024-04-24 トリループを含む二本鎖核酸インヒビター分子

Country Status (13)

Country Link
US (1) US20220064640A1 (https=)
EP (1) EP3894560A4 (https=)
JP (2) JP7535047B2 (https=)
KR (1) KR20210127917A (https=)
CN (1) CN113454221A (https=)
AU (1) AU2019397247A1 (https=)
BR (1) BR112021011294A2 (https=)
CA (1) CA3122930A1 (https=)
CL (1) CL2021001552A1 (https=)
IL (1) IL283775A (https=)
MX (1) MX2021007001A (https=)
SG (1) SG11202106046XA (https=)
WO (1) WO2020123083A1 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2019397247A1 (en) * 2018-12-12 2021-06-24 Dicerna Pharmaceuticals, Inc. Double-stranded nucleic acid inhibitor molecules containing a triloop
WO2020226960A1 (en) 2019-05-03 2020-11-12 Dicerna Pharmaceuticals, Inc. Double-stranded nucleic acid inhibitor molecules with shortened sense strands
MX2023001450A (es) * 2020-08-04 2023-04-14 Dicerna Pharmaceuticals Inc Composiciones y metodos para la inhibicion de la expresion de plp1.
CA3226019A1 (en) 2021-07-20 2023-01-26 Ags Therapeutics Sas Extracellular vesicles from microalgae, their preparation, and uses
WO2023144127A1 (en) 2022-01-31 2023-08-03 Ags Therapeutics Sas Extracellular vesicles from microalgae, their biodistribution upon administration, and uses
KR20250005108A (ko) * 2022-04-15 2025-01-09 다이서나 파마수이티컬, 인크. Scap 활성을 조절하기 위한 조성물 및 방법
WO2023232976A1 (en) 2022-06-03 2023-12-07 Ags Therapeutics Sas Extracellular vesicles from genetically-modified microalgae containing endogenously-loaded cargo, their preparation, and uses
CN121038801A (zh) 2022-10-24 2025-11-28 Ags治疗简易股份公司 来自微藻的细胞外囊泡、它们在鼻内施用时的生物分布及其用途
WO2025176847A1 (en) 2024-02-21 2025-08-28 Ags Therapeutics Sas Ocular delivery of active agents via microalgae extracellular vesicles

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8067572B2 (en) * 2005-05-25 2011-11-29 The University Of York Hybrid interfering RNA
JP2012504389A (ja) * 2008-09-22 2012-02-23 ダイセルナ ファーマシューティカルズ, インコーポレイテッド 修飾を有するdsRNAによる遺伝子発現の特異的な阻害のための組成物および方法
EP2363467B1 (en) * 2008-10-23 2015-12-16 The University of Tokyo Method for inhibiting function of micro-rna
EP3358014B1 (en) * 2010-04-19 2020-12-23 TAGCyx Biotechnologies Inc. Method for stabilizing functional nucleic acids
EP2781598B1 (en) * 2011-11-16 2018-08-08 Osaka City University Nucleic acid molecule for inhibiting activity of rnai molecule
JP7105065B2 (ja) * 2014-12-15 2022-07-22 ダイセルナ ファーマシューティカルズ, インコーポレイテッド リガンド修飾二本鎖核酸
JP6987084B2 (ja) * 2016-03-16 2021-12-22 ディセルナ ファーマシューティカルズ インコーポレイテッド β−カテニン関連疾患又は障害の治療のための組成物及び方法
KR102350647B1 (ko) * 2016-09-02 2022-01-14 다이서나 파마수이티컬, 인크. 4'-포스페이트 유사체 및 이를 포함하는 올리고뉴클레오타이드
KR20200023427A (ko) * 2017-06-29 2020-03-04 다이서나 파마수이티컬, 인크. Hmgb1 발현을 억제하기 위한 조성물 및 방법
CA3094008A1 (en) * 2018-04-13 2019-10-17 Dicerna Pharmaceuticals, Inc. Double-stranded nucleic acid inhibitor molecules modified with tm-increasing nucleotides
AU2019397247A1 (en) 2018-12-12 2021-06-24 Dicerna Pharmaceuticals, Inc. Double-stranded nucleic acid inhibitor molecules containing a triloop

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