JP2022521787A5 - - Google Patents

Info

Publication number
JP2022521787A5
JP2022521787A5 JP2021549970A JP2021549970A JP2022521787A5 JP 2022521787 A5 JP2022521787 A5 JP 2022521787A5 JP 2021549970 A JP2021549970 A JP 2021549970A JP 2021549970 A JP2021549970 A JP 2021549970A JP 2022521787 A5 JP2022521787 A5 JP 2022521787A5
Authority
JP
Japan
Prior art keywords
item
cells
donor dna
nucleotides
population
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
JP2021549970A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022521787A (ja
Filing date
Publication date
Priority claimed from US16/288,052 external-priority patent/US20200224160A1/en
Application filed filed Critical
Publication of JP2022521787A publication Critical patent/JP2022521787A/ja
Publication of JP2022521787A5 publication Critical patent/JP2022521787A5/ja
Priority to JP2024219750A priority Critical patent/JP2025061660A/ja
Ceased legal-status Critical Current

Links

JP2021549970A 2018-02-27 2020-02-27 Rna誘導型エンドヌクレアーゼを使用するdna組み込みのための改善された方法 Ceased JP2022521787A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024219750A JP2025061660A (ja) 2018-02-27 2024-12-16 Rna誘導型エンドヌクレアーゼを使用するdna組み込みのための改善された方法

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201862635702P 2018-02-27 2018-02-27
US16/288,052 2019-02-27
US16/288,052 US20200224160A1 (en) 2018-02-27 2019-02-27 Process for dna integration using rna-guided endonucleases
PCT/US2020/020121 WO2020176740A1 (en) 2018-02-27 2020-02-27 Improved process for dna integration using rna-guided endonucleases

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2024219750A Division JP2025061660A (ja) 2018-02-27 2024-12-16 Rna誘導型エンドヌクレアーゼを使用するdna組み込みのための改善された方法

Publications (2)

Publication Number Publication Date
JP2022521787A JP2022521787A (ja) 2022-04-12
JP2022521787A5 true JP2022521787A5 (enExample) 2023-03-07

Family

ID=71516309

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021549970A Ceased JP2022521787A (ja) 2018-02-27 2020-02-27 Rna誘導型エンドヌクレアーゼを使用するdna組み込みのための改善された方法
JP2024219750A Pending JP2025061660A (ja) 2018-02-27 2024-12-16 Rna誘導型エンドヌクレアーゼを使用するdna組み込みのための改善された方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2024219750A Pending JP2025061660A (ja) 2018-02-27 2024-12-16 Rna誘導型エンドヌクレアーゼを使用するdna組み込みのための改善された方法

Country Status (11)

Country Link
US (2) US20200224160A1 (enExample)
EP (1) EP3931322A1 (enExample)
JP (2) JP2022521787A (enExample)
KR (1) KR20210134000A (enExample)
CN (1) CN113906136A (enExample)
AU (1) AU2020229848A1 (enExample)
CA (1) CA3131588A1 (enExample)
IL (1) IL285842A (enExample)
MX (1) MX2021010322A (enExample)
SG (1) SG11202109332RA (enExample)
WO (1) WO2020176740A1 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2015330699B2 (en) 2014-10-10 2021-12-02 Editas Medicine, Inc. Compositions and methods for promoting homology directed repair
WO2019165168A1 (en) 2018-02-23 2019-08-29 Pioneer Hi-Bred International, Inc. Novel cas9 orthologs
WO2020123887A2 (en) 2018-12-14 2020-06-18 Pioneer Hi-Bred International, Inc. Novel crispr-cas systems for genome editing
KR20210133261A (ko) * 2019-02-26 2021-11-05 소렌토 쎄라퓨틱스, 인코포레이티드 Bcma에 결합하는 항원 결합 단백질
EP3773918A4 (en) 2019-03-05 2022-01-05 Nkarta, Inc. CD19 DIRECTED CHIMERIC ANTIGEN RECEPTORS AND THEIR USES IN IMMUNOTHERAPY
EP3980533A1 (en) 2019-06-07 2022-04-13 Scribe Therapeutics Inc. Engineered casx systems
EP4139345A1 (en) 2020-04-24 2023-03-01 Sorrento Therapeutics, Inc. Memory dimeric antigen receptors
WO2022015956A1 (en) 2020-07-15 2022-01-20 Sorrento Therapeutics, Inc. Improved process for dna integration using rna-guided endonucleases
AU2021320556A1 (en) * 2020-08-07 2023-03-09 Neogene Therapeutics B.V. Methods to enrich genetically engineered T cells
JP2023550323A (ja) 2020-11-11 2023-12-01 モンサント テクノロジー エルエルシー 部位特異的組込み頻度を改善するための方法
KR20230128289A (ko) 2020-12-03 2023-09-04 스크라이브 테라퓨틱스 인크. 조작된 클래스 2 유형 v crispr 시스템
WO2022215978A1 (ko) * 2021-04-05 2022-10-13 주식회사 셀렌진 Pdcd-1 유전자에 상보적인 가이드 rna 및 이의 용도
WO2026020171A2 (en) 2024-07-19 2026-01-22 Aera Therapeutics, Inc. Chimeric antigen receptor constructs

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6010907A (en) * 1998-05-12 2000-01-04 Kimeragen, Inc. Eukaryotic use of non-chimeric mutational vectors
US6556674B1 (en) 1998-11-19 2003-04-29 Legerity, Inc. Signal detector with matched filter coefficient
US9957515B2 (en) * 2013-03-15 2018-05-01 Cibus Us Llc Methods and compositions for targeted gene modification
WO2014191128A1 (en) * 2013-05-29 2014-12-04 Cellectis Methods for engineering t cells for immunotherapy by using rna-guided cas nuclease system
WO2017070429A1 (en) * 2015-10-22 2017-04-27 Regents Of The University Of Minnesota Methods involving editing polynucleotides that encode t cell receptor
EP4628587A3 (en) * 2016-04-15 2026-02-25 Memorial Sloan Kettering Cancer Center Transgenic t cell and chimeric antigen receptor t cell compositions and related methods
US10428327B2 (en) * 2016-05-27 2019-10-01 Life Technologies Corporation Compositions and methods for enhancing homologous recombination
WO2018023631A1 (zh) * 2016-08-04 2018-02-08 汤隆初 自动浇水技术的使用情况反馈方法以及自动浇水装置
WO2018073391A1 (en) * 2016-10-19 2018-04-26 Cellectis Targeted gene insertion for improved immune cells therapy
EP3679144A1 (en) * 2017-09-08 2020-07-15 Life Technologies Corporation Methods for improved homologous recombination and compositions thereof
EP3781677A4 (en) * 2018-04-16 2022-01-19 University of Massachusetts COMPOSITIONS AND METHODS FOR IMPROVED GENE EDITTING

Similar Documents

Publication Publication Date Title
JP2022521787A5 (enExample)
JP7579820B2 (ja) 化学修飾を有するガイドrna
JP7038079B2 (ja) Crisprハイブリッドdna/rnaポリヌクレオチドおよび使用方法
KR102738283B1 (ko) 암 면역요법을 위한 crispr-cpf1-관련 방법, 조성물 및 구성성분
ES2884838T3 (es) ARN guía químicamente modificados para la regulación génica mediada por CRISPR/CAS
US10526590B2 (en) Compounds and methods for CRISPR/Cas-based genome editing by homologous recombination
AU2024259841A1 (en) CRISPR-Cas-related methods, compositions and components for cancer immunotherapy
JP2022137068A (ja) 化学的に修飾されたガイドrnaを使用する高特異性ゲノム編集
EP3464323B1 (en) Peptides and nanoparticles for intracellular delivery of genome-editing molecules
AU2020201465A1 (en) Using truncated guide rnas (tru-grnas) to increase specificity for rna-guided genome editing
JP2022524435A5 (enExample)
WO2016161380A1 (en) Crispr/cas-related methods and compositions for treating duchenne muscular dystrophy and becker muscular dystrophy
EP4399294A1 (en) Guide rnas with chemical modification for prime editing
US20250257342A1 (en) Peptides and nanoparticles for intracellular delivery of genome-editing molecules
RU2020100919A (ru) СПОСОБ НОКАУТИРОВАНИЯ ГЕНА-МИШЕНИ В T-КЛЕТКЕ IN VITRO И crRNA, ПРИМЕНЯЕМАЯ В ДАННОМ СПОСОБЕ
JP2024533448A (ja) 化学修飾を有するガイドrnaを使用する方法
CA3253302A1 (en) CELL COMPOSITIONS AND ENGINEERING METHODS
HK40064529A (en) Peptides and nanoparticles for intracellular delivery of genome-editing molecules
CA3230928A1 (en) Methods for using guide rnas with chemical modifications
HK40006957B (en) Peptides and nanoparticles for intracellular delivery of genome-editing molecules