JP2022521537A5 - - Google Patents
Info
- Publication number
- JP2022521537A5 JP2022521537A5 JP2021549328A JP2021549328A JP2022521537A5 JP 2022521537 A5 JP2022521537 A5 JP 2022521537A5 JP 2021549328 A JP2021549328 A JP 2021549328A JP 2021549328 A JP2021549328 A JP 2021549328A JP 2022521537 A5 JP2022521537 A5 JP 2022521537A5
- Authority
- JP
- Japan
- Prior art keywords
- fluoro
- pyridine
- imidazo
- carboxamide
- cyclopropane
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962809230P | 2019-02-22 | 2019-02-22 | |
| US62/809,230 | 2019-02-22 | ||
| PCT/IB2020/051472 WO2020170206A1 (en) | 2019-02-22 | 2020-02-21 | Imidazopyridinyl compounds and use thereof for treatment of proliferative disorders |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022521537A JP2022521537A (ja) | 2022-04-08 |
| JP2022521537A5 true JP2022521537A5 (https=) | 2023-03-01 |
Family
ID=72141573
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021549327A Active JP7609790B2 (ja) | 2019-02-22 | 2020-02-21 | イミダゾピリジニル化合物及び神経変性障害の処置のためのその使用 |
| JP2021549328A Pending JP2022521537A (ja) | 2019-02-22 | 2020-02-21 | イミダゾピリジニル化合物及び増殖性障害の処置のためのその使用 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021549327A Active JP7609790B2 (ja) | 2019-02-22 | 2020-02-21 | イミダゾピリジニル化合物及び神経変性障害の処置のためのその使用 |
Country Status (10)
| Country | Link |
|---|---|
| US (4) | US20220242861A1 (https=) |
| EP (2) | EP3927706A4 (https=) |
| JP (2) | JP7609790B2 (https=) |
| KR (2) | KR102892275B1 (https=) |
| CN (2) | CN113454081B (https=) |
| AU (1) | AU2020224401A1 (https=) |
| CA (1) | CA3131059A1 (https=) |
| IL (1) | IL285708B2 (https=) |
| MX (1) | MX2021010122A (https=) |
| WO (2) | WO2020170205A1 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2020224401A1 (en) | 2019-02-22 | 2021-10-14 | 1ST Biotherapeutics, Inc. | Imidazopyridinyl compounds and use thereof for treatment of neurodegenerative disorders |
| CN115968362B (zh) * | 2020-08-21 | 2025-06-13 | 第一生物治疗股份有限公司 | 作为pet放射性示踪剂的[18f]-标记的咪唑并吡啶衍生物 |
| US12398156B2 (en) | 2020-08-21 | 2025-08-26 | 1ST Biotherapeutics, Inc. | Compounds for prevention or treatment of neurodegenerative disorders |
| WO2022064459A1 (en) * | 2020-09-28 | 2022-03-31 | 1ST Biotherapeutics, Inc. | Indazoles as hematopoietic progenitor kinase 1 (hpk1) inhibitors and methods of using same |
| EP4236950A4 (en) * | 2020-10-29 | 2024-10-23 | Merck Sharp & Dohme LLC | N-LINKED ISOQUINOLINE AMIDES AS LRRK2 INHIBITORS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF |
| WO2022165529A1 (en) * | 2021-02-01 | 2022-08-04 | Janssen Biotech, Inc. | Small molecule inhibitors of salt inducible kinases |
| CN115724839A (zh) * | 2021-08-26 | 2023-03-03 | 科辉智药生物科技(深圳)有限公司 | Sarm1酶活性抑制剂及其应用 |
| EP4499643A4 (en) * | 2022-03-25 | 2026-01-28 | 1St Biotherapeutics Inc | INDAZOLES USED AS HEMATOPOIETIC PROGENITOR KINASE 1 (HPK1) INHIBITORS AND THEIR METHODS OF USE |
| CN116354959B (zh) * | 2023-03-10 | 2024-04-19 | 石河子大学 | 一种N-N桥连噻唑单元的β-咔啉衍生物及其制备方法、应用 |
| CN121941688A (zh) * | 2023-10-09 | 2026-04-28 | 浙江海正药业股份有限公司 | 多取代芳基类衍生物及其制备方法和用途 |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20020084116A (ko) | 2000-02-07 | 2002-11-04 | 애보트 게엠베하 운트 콤파니 카게 | 2-벤조티아졸릴 우레아 유도체 및 이의 단백질 키나제억제제로서의 용도 |
| CN101384586A (zh) * | 2006-02-14 | 2009-03-11 | 诺华公司 | Pi-3激酶抑制剂及其应用方法 |
| PE20070978A1 (es) * | 2006-02-14 | 2007-11-15 | Novartis Ag | COMPUESTOS HETEROCICLICOS COMO INHIBIDORES DE FOSFATIDILINOSITOL 3-QUINASAS (PI3Ks) |
| EP2058309A4 (en) | 2006-08-04 | 2010-12-22 | Takeda Pharmaceutical | CONDENSED HETEROCYCLIC COMPOUND |
| CA2693232A1 (en) | 2007-07-18 | 2009-01-22 | Novartis Ag | Bicyclic heteroaryl compounds and their use as kinase inhibitors |
| TW200911798A (en) | 2007-08-02 | 2009-03-16 | Amgen Inc | PI3 kinase modulators and methods of use |
| ES2400604T3 (es) * | 2007-08-17 | 2013-04-11 | Icagen, Inc. | Heterociclos como moduladores del canal de potasio |
| AU2008343813B2 (en) * | 2007-12-19 | 2012-04-12 | Amgen Inc. | Inhibitors of PI3 kinase |
| US8993580B2 (en) | 2008-03-14 | 2015-03-31 | Intellikine Llc | Benzothiazole kinase inhibitors and methods of use |
| AR071523A1 (es) | 2008-04-30 | 2010-06-23 | Merck Serono Sa | Compuestos biciclicos fusionados, un proceso para su preparacion, el compuesto para ser utilizado como medicamento en el tratamiento y profilaxis de enfermedades, una composicion farmaceutica y un conjunto que comprende paquetes separados del compuesto y de un ingrediente activo del medicamento |
| WO2010008847A2 (en) | 2008-06-24 | 2010-01-21 | Takeda Pharmaceutical Company Limited | Pi3k/m tor inhibitors |
| BRPI0915231A2 (pt) | 2008-07-08 | 2018-06-12 | Intellikine Inc | compostos inibidores de quinase e métodos de uso |
| WO2010100144A1 (en) | 2009-03-04 | 2010-09-10 | Merck Serono S.A. | Fused bicyclic compounds as inhibitors for pi3 kinase |
| US8765747B2 (en) * | 2009-06-12 | 2014-07-01 | Dana-Farber Cancer Institute, Inc. | Fused 2-aminothiazole compounds |
| NZ598220A (en) * | 2009-08-17 | 2014-02-28 | Intellikine Llc | Heterocyclic compounds and uses thereof |
| EA026115B1 (ru) * | 2010-12-17 | 2017-03-31 | Ф. Хоффманн-Ля Рош Аг | Замещенные 6,6-конденсированные азотсодержащие гетероциклические соединения и их применение |
| WO2014004863A2 (en) * | 2012-06-27 | 2014-01-03 | Alzheimer's Institute Of America, Inc. | Compounds, compositions, and therapeutic uses thereof |
| EP2892534B8 (en) | 2012-09-06 | 2021-09-15 | Plexxikon Inc. | Compounds and methods for kinase modulation, and indications therefor |
| MX365640B (es) | 2012-12-21 | 2019-06-10 | Plexxikon Inc | Compuestos y metodos para la modulacion de quinasas y sus indicaciones. |
| US9598424B2 (en) * | 2014-03-06 | 2017-03-21 | Takeda Pharmaceutical Company Limited | Heteroarylamide inhibitors of TBK1 |
| WO2018017435A1 (en) * | 2016-07-22 | 2018-01-25 | Accro Bioscience Inc. | Heteroaryl compounds as inhibitors of necrosis, composition and application thereof |
| WO2018237370A1 (en) * | 2017-06-23 | 2018-12-27 | Accro Bioscience Inc. | Heteroaryl compounds as inhibitors of necrosis, composition and method using the same |
| AU2018346051B2 (en) | 2017-10-02 | 2022-11-10 | 1st Biotherapeutics Inc. | Benzothiazol compounds and methods using the same for treating neurodegenerative disorders |
| EP3877371A4 (en) * | 2018-11-07 | 2022-07-27 | Dana-Farber Cancer Institute, Inc. | IMIDAZOPYRIDINE DERIVATIVES AND AZA-IMIDAZOPYRIDINE DERIVATIVES AS JANUS KINASE 2 INHIBITORS AND USES THEREOF |
| AU2020224401A1 (en) * | 2019-02-22 | 2021-10-14 | 1ST Biotherapeutics, Inc. | Imidazopyridinyl compounds and use thereof for treatment of neurodegenerative disorders |
-
2020
- 2020-02-21 AU AU2020224401A patent/AU2020224401A1/en not_active Abandoned
- 2020-02-21 CN CN202080014118.3A patent/CN113454081B/zh active Active
- 2020-02-21 MX MX2021010122A patent/MX2021010122A/es unknown
- 2020-02-21 KR KR1020217030103A patent/KR102892275B1/ko active Active
- 2020-02-21 WO PCT/IB2020/051469 patent/WO2020170205A1/en not_active Ceased
- 2020-02-21 EP EP20759969.7A patent/EP3927706A4/en active Pending
- 2020-02-21 JP JP2021549327A patent/JP7609790B2/ja active Active
- 2020-02-21 US US17/432,497 patent/US20220242861A1/en not_active Abandoned
- 2020-02-21 EP EP20759163.7A patent/EP3927705A4/en active Pending
- 2020-02-21 IL IL285708A patent/IL285708B2/en unknown
- 2020-02-21 US US16/797,140 patent/US11098044B2/en active Active
- 2020-02-21 WO PCT/IB2020/051472 patent/WO2020170206A1/en not_active Ceased
- 2020-02-21 CN CN202080014156.9A patent/CN113454082B/zh active Active
- 2020-02-21 JP JP2021549328A patent/JP2022521537A/ja active Pending
- 2020-02-21 CA CA3131059A patent/CA3131059A1/en active Pending
- 2020-02-21 KR KR1020217030099A patent/KR20210122861A/ko not_active Withdrawn
-
2021
- 2021-07-12 US US17/372,863 patent/US11802126B2/en active Active
-
2023
- 2023-07-19 US US18/223,860 patent/US12534461B2/en active Active
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