JP2022521240A5 - - Google Patents
Info
- Publication number
- JP2022521240A5 JP2022521240A5 JP2021548701A JP2021548701A JP2022521240A5 JP 2022521240 A5 JP2022521240 A5 JP 2022521240A5 JP 2021548701 A JP2021548701 A JP 2021548701A JP 2021548701 A JP2021548701 A JP 2021548701A JP 2022521240 A5 JP2022521240 A5 JP 2022521240A5
- Authority
- JP
- Japan
- Prior art keywords
- domain
- scfv
- seq
- baff
- igg4
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962808222P | 2019-02-20 | 2019-02-20 | |
| US62/808,222 | 2019-02-20 | ||
| PCT/US2020/019082 WO2020172440A1 (en) | 2019-02-20 | 2020-02-20 | Baff-r/cd19 targeted chimeric antigen receptor-modified t cells and use thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022521240A JP2022521240A (ja) | 2022-04-06 |
| JP2022521240A5 true JP2022521240A5 (https=) | 2023-02-13 |
| JP7593646B2 JP7593646B2 (ja) | 2024-12-03 |
Family
ID=69845600
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021548701A Active JP7593646B2 (ja) | 2019-02-20 | 2020-02-20 | Ｂａｆｆ－ｒ／ｃｄ１９を標的としたキメラ抗原受容体修飾ｔ細胞とその使用 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US12545714B2 (https=) |
| EP (1) | EP3927738A1 (https=) |
| JP (1) | JP7593646B2 (https=) |
| KR (1) | KR20210129125A (https=) |
| CN (1) | CN113874391B (https=) |
| WO (1) | WO2020172440A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN121405815A (zh) * | 2018-12-19 | 2026-01-27 | 希望之城 | Baff-r双特异性t细胞衔接子抗体 |
| EP3773918A4 (en) | 2019-03-05 | 2022-01-05 | Nkarta, Inc. | CD19 DIRECTED CHIMERIC ANTIGEN RECEPTORS AND THEIR USES IN IMMUNOTHERAPY |
| WO2021163989A1 (en) * | 2020-02-21 | 2021-08-26 | Yinnuolai Biotech Ltd. | Anti-baff receptor antibodies and uses thereof |
| EP4271817A2 (en) | 2020-12-30 | 2023-11-08 | Alaunos Therapeutics, Inc. | Recombinant vectors comprising polycistronic expression cassettes and methods of use thereof |
| US20250319130A1 (en) * | 2022-06-01 | 2025-10-16 | Seattle Children’s Hospital d/b/a Seattle Children’s Research Institute | Recombinant receptors binding b cell activation factor receptor and uses thereof |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9657105B2 (en) | 2013-03-15 | 2017-05-23 | City Of Hope | CD123-specific chimeric antigen receptor redirected T cells and methods of their use |
| DE102014105472B4 (de) | 2014-04-16 | 2016-03-17 | Sartorius Stedim Biotech Gmbh | Misch- und Auftauvorrichtung |
| CA2945388A1 (en) | 2014-04-23 | 2015-10-29 | Board Of Regents, The University Of Texas System | Chimeric antigen receptors (car) for use in therapy and methods for making the same |
| TWI751102B (zh) | 2014-08-28 | 2022-01-01 | 美商奇諾治療有限公司 | 對ｃｄ１９具專一性之抗體及嵌合抗原受體 |
| US10738116B2 (en) | 2015-03-19 | 2020-08-11 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Dual specific anti-CD22-anti-CD19 chimeric antigen receptors |
| AU2016306209B2 (en) | 2015-08-07 | 2023-07-06 | Seattle Children's Hospital (dba Seattle Children's Research Institute) | Bispecific CAR T-cells for solid tumor targeting |
| EP4628094A3 (en) | 2016-06-06 | 2025-12-31 | City of Hope | BAFF-R ANTIBODIES AND THEIR USES |
| IL308798A (en) * | 2016-06-06 | 2024-01-01 | Univ Texas | Baff-r targeted chimeric antigen receptor-modified t-cells and uses thereof |
| CN108728459B (zh) | 2017-04-24 | 2023-08-04 | 上海恒润达生生物科技股份有限公司 | 靶向cd19的嵌合抗原受体并联合表达il-15的方法和用途 |
| CN110650975B (zh) * | 2017-05-15 | 2024-04-05 | 美国卫生和人力服务部 | 双顺反子嵌合抗原受体及其用途 |
| CA3287539A1 (en) | 2017-06-21 | 2026-03-02 | Icell Gene Therapeutics Llc | CHIMERIC ANTIGEN RECEPTORS (CARs), COMPOSITIONS AND METHODS THEREOF |
-
2020
- 2020-02-20 CN CN202080028641.1A patent/CN113874391B/zh active Active
- 2020-02-20 EP EP20712162.5A patent/EP3927738A1/en active Pending
- 2020-02-20 US US17/432,283 patent/US12545714B2/en active Active
- 2020-02-20 JP JP2021548701A patent/JP7593646B2/ja active Active
- 2020-02-20 WO PCT/US2020/019082 patent/WO2020172440A1/en not_active Ceased
- 2020-02-20 KR KR1020217029730A patent/KR20210129125A/ko active Pending
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