JP2025081512A5 - - Google Patents

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Publication number
JP2025081512A5
JP2025081512A5 JP2025024834A JP2025024834A JP2025081512A5 JP 2025081512 A5 JP2025081512 A5 JP 2025081512A5 JP 2025024834 A JP2025024834 A JP 2025024834A JP 2025024834 A JP2025024834 A JP 2025024834A JP 2025081512 A5 JP2025081512 A5 JP 2025081512A5
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JP
Japan
Prior art keywords
seq
cancer
cdr
domain
set forth
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2025024834A
Other languages
English (en)
Japanese (ja)
Other versions
JP2025081512A (ja
Filing date
Publication date
Priority claimed from PCT/US2020/025069 external-priority patent/WO2020198531A2/en
Application filed filed Critical
Publication of JP2025081512A publication Critical patent/JP2025081512A/ja
Publication of JP2025081512A5 publication Critical patent/JP2025081512A5/ja
Pending legal-status Critical Current

Links

JP2025024834A 2019-03-26 2025-02-19 血液がんおよび固形がんの治療のためのキメラ抗原受容体改変t細胞(car-t) Pending JP2025081512A (ja)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US201962824080P 2019-03-26 2019-03-26
US62/824,080 2019-03-26
US201962931103P 2019-11-05 2019-11-05
US62/931,103 2019-11-05
US202062969569P 2020-02-03 2020-02-03
US62/969,569 2020-02-03
PCT/US2020/025069 WO2020198531A2 (en) 2019-03-26 2020-03-26 Chimeric antigen receptor modified t-cells (car-t) for the treatment of hematological and solid tumor cancers
JP2021557377A JP2022527081A (ja) 2019-03-26 2020-03-26 血液がんおよび固形がんの治療のためのキメラ抗原受容体改変t細胞(car-t)

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2021557377A Division JP2022527081A (ja) 2019-03-26 2020-03-26 血液がんおよび固形がんの治療のためのキメラ抗原受容体改変t細胞(car-t)

Publications (2)

Publication Number Publication Date
JP2025081512A JP2025081512A (ja) 2025-05-27
JP2025081512A5 true JP2025081512A5 (https=) 2025-07-31

Family

ID=72610137

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021557377A Pending JP2022527081A (ja) 2019-03-26 2020-03-26 血液がんおよび固形がんの治療のためのキメラ抗原受容体改変t細胞(car-t)
JP2025024834A Pending JP2025081512A (ja) 2019-03-26 2025-02-19 血液がんおよび固形がんの治療のためのキメラ抗原受容体改変t細胞(car-t)

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2021557377A Pending JP2022527081A (ja) 2019-03-26 2020-03-26 血液がんおよび固形がんの治療のためのキメラ抗原受容体改変t細胞(car-t)

Country Status (11)

Country Link
US (1) US20230312708A1 (https=)
EP (1) EP3953372A4 (https=)
JP (2) JP2022527081A (https=)
KR (1) KR20210143804A (https=)
CN (1) CN113710688A (https=)
AU (1) AU2020248448B2 (https=)
CA (1) CA3134465A1 (https=)
IL (1) IL286618A (https=)
MX (1) MX2021011494A (https=)
SG (1) SG11202110131SA (https=)
WO (1) WO2020198531A2 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20240415883A1 (en) * 2021-02-01 2024-12-19 The Regents Of The University Of California Treatment of neuroendocrine cancers
AU2022227686A1 (en) 2021-02-25 2023-07-27 Lyell Immunopharma, Inc. Ror1 targeting chimeric antigen receptor
WO2023217227A1 (zh) 2022-05-12 2023-11-16 先声再明医药有限公司 喜树碱类衍生物及配体-药物偶联物
US12600801B2 (en) * 2022-07-11 2026-04-14 Fred Hutchinson Cancer Center Single-domain antibodies that bind ROR1
WO2025076113A1 (en) 2023-10-05 2025-04-10 Capstan Therapeutics, Inc. Ionizable cationic lipids with conserved spacing and lipid nanoparticles
WO2025076127A1 (en) 2023-10-05 2025-04-10 Capstan Therapeutics, Inc. Constrained ionizable cationic lipids and lipid nanoparticles
KR20250052305A (ko) * 2023-10-10 2025-04-18 서울대학교산학협력단 키메라 항원 수용체를 발현하는 자연 살해 세포를 이용한 종양 미세환경의 주피세포를 표적하는 항암 세포 치료 기법 및 치료 효능 평가를 위한 종양 미세환경 오가노이드 모델 제작 기술
WO2025217454A2 (en) 2024-04-11 2025-10-16 Capstan Therapeutics, Inc. Ionizable cationic lipids and lipid nanoparticles
WO2025217452A1 (en) 2024-04-11 2025-10-16 Capstan Therapeutics, Inc. Constrained ionizable cationic lipids and lipid nanoparticles

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130266551A1 (en) * 2003-11-05 2013-10-10 St. Jude Children's Research Hospital, Inc. Chimeric receptors with 4-1bb stimulatory signaling domain
PL3489261T3 (pl) * 2012-08-24 2021-08-16 The Regents Of The University Of California Przeciwciała i szczepionki do stosowania w leczeniu nowotworów z ekspresją ROR1 i w hamowaniu przerzutu
KR102048855B1 (ko) * 2014-07-29 2019-11-26 셀렉티스 암 면역요법을 위한 ror1(ntrkr1) 특이적 키메라 항원 수용체
AU2015343013B2 (en) * 2014-11-05 2020-07-16 Board Of Regents, The University Of Texas System Gene modified immune effector cells and engineered cells for expansion of immune effector cells
JP6865688B2 (ja) * 2015-01-16 2021-04-28 ジュノー セラピューティクス インコーポレイテッド Ror1に特異的な抗体およびキメラ抗原受容体
KR20190003938A (ko) * 2016-02-25 2019-01-10 셀 메디카 스위처란트 아게 면역치료를 위한 변형된 세포
EP3523331A1 (en) * 2016-10-07 2019-08-14 Novartis AG Chimeric antigen receptors for the treatment of cancer
CN108424458A (zh) * 2017-02-13 2018-08-21 上海恒润达生生物科技有限公司 靶向ny-eso-1的嵌合抗原受体及其用途
MX2019015057A (es) * 2017-06-23 2020-08-03 Velosbio Inc Inmunoconjugados de anticuerpos receptor huérfano similar al receptor tirosina cinasa 1 (ror1).
BR112022009611A2 (pt) * 2019-11-18 2022-08-09 Univ California Anticorpos anti-ror-2 e métodos de uso

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