JP2022519127A - 柑橘類繊維及びスクレログルカン組成物、並びにパーソナルケア用途におけるそれらの使用 - Google Patents
柑橘類繊維及びスクレログルカン組成物、並びにパーソナルケア用途におけるそれらの使用 Download PDFInfo
- Publication number
- JP2022519127A JP2022519127A JP2021544929A JP2021544929A JP2022519127A JP 2022519127 A JP2022519127 A JP 2022519127A JP 2021544929 A JP2021544929 A JP 2021544929A JP 2021544929 A JP2021544929 A JP 2021544929A JP 2022519127 A JP2022519127 A JP 2022519127A
- Authority
- JP
- Japan
- Prior art keywords
- weight
- emulsion
- glucan
- oil
- blend
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 143
- 235000020971 citrus fruits Nutrition 0.000 title claims abstract description 116
- 241000207199 Citrus Species 0.000 title claims abstract description 112
- 239000000835 fiber Substances 0.000 title claims abstract description 112
- 229920002305 Schizophyllan Polymers 0.000 title claims description 35
- FEBUJFMRSBAMES-UHFFFAOYSA-N 2-[(2-{[3,5-dihydroxy-2-(hydroxymethyl)-6-phosphanyloxan-4-yl]oxy}-3,5-dihydroxy-6-({[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)oxan-4-yl)oxy]-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl phosphinite Chemical compound OC1C(O)C(O)C(CO)OC1OCC1C(O)C(OC2C(C(OP)C(O)C(CO)O2)O)C(O)C(OC2C(C(CO)OC(P)C2O)O)O1 FEBUJFMRSBAMES-UHFFFAOYSA-N 0.000 title claims description 32
- 239000000839 emulsion Substances 0.000 claims abstract description 98
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 claims abstract description 82
- 229920002498 Beta-glucan Polymers 0.000 claims abstract description 76
- 238000000034 method Methods 0.000 claims abstract description 34
- 239000012049 topical pharmaceutical composition Substances 0.000 claims abstract description 26
- 239000003921 oil Substances 0.000 claims description 65
- 235000019198 oils Nutrition 0.000 claims description 65
- 239000012071 phase Substances 0.000 claims description 39
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 35
- 239000008346 aqueous phase Substances 0.000 claims description 33
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 18
- 239000002453 shampoo Substances 0.000 claims description 11
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims description 9
- 239000008103 glucose Substances 0.000 claims description 8
- 150000004676 glycans Chemical class 0.000 claims description 8
- 229920001282 polysaccharide Polymers 0.000 claims description 8
- 239000005017 polysaccharide Substances 0.000 claims description 8
- 238000002360 preparation method Methods 0.000 claims description 7
- 239000006210 lotion Substances 0.000 claims description 6
- 238000002156 mixing Methods 0.000 claims description 6
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 claims description 5
- 229930006000 Sucrose Natural products 0.000 claims description 5
- 238000000265 homogenisation Methods 0.000 claims description 5
- 102000004169 proteins and genes Human genes 0.000 claims description 5
- 108090000623 proteins and genes Proteins 0.000 claims description 5
- 150000003839 salts Chemical class 0.000 claims description 5
- 239000005720 sucrose Substances 0.000 claims description 5
- 230000000699 topical effect Effects 0.000 claims description 5
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 claims description 4
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 claims description 4
- 239000013543 active substance Substances 0.000 claims description 4
- 239000002537 cosmetic Substances 0.000 claims description 4
- 239000006071 cream Substances 0.000 claims description 4
- 239000003995 emulsifying agent Substances 0.000 claims description 4
- 239000007764 o/w emulsion Substances 0.000 claims description 4
- 239000000049 pigment Substances 0.000 claims description 4
- 229920005862 polyol Polymers 0.000 claims description 4
- 150000003077 polyols Chemical class 0.000 claims description 4
- 239000003755 preservative agent Substances 0.000 claims description 4
- 239000000344 soap Substances 0.000 claims description 4
- 239000000600 sorbitol Substances 0.000 claims description 4
- 235000000346 sugar Nutrition 0.000 claims description 4
- 150000008163 sugars Chemical class 0.000 claims description 4
- 235000019484 Rapeseed oil Nutrition 0.000 claims description 3
- 239000000975 dye Substances 0.000 claims description 3
- 239000011785 micronutrient Substances 0.000 claims description 3
- 235000013369 micronutrients Nutrition 0.000 claims description 3
- 235000015097 nutrients Nutrition 0.000 claims description 3
- 229920001296 polysiloxane Polymers 0.000 claims description 3
- 235000018102 proteins Nutrition 0.000 claims description 3
- 210000004761 scalp Anatomy 0.000 claims description 3
- 238000011282 treatment Methods 0.000 claims description 3
- 235000013343 vitamin Nutrition 0.000 claims description 3
- 239000011782 vitamin Substances 0.000 claims description 3
- 229940088594 vitamin Drugs 0.000 claims description 3
- 229930003231 vitamin Natural products 0.000 claims description 3
- 230000000475 sunscreen effect Effects 0.000 claims description 2
- 239000000516 sunscreening agent Substances 0.000 claims description 2
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 claims description 2
- FYGDTMLNYKFZSV-WFYNLLPOSA-N (2s,3r,4s,5s,6r)-2-[(2r,4r,5r,6s)-4,5-dihydroxy-2-(hydroxymethyl)-6-[(2r,3s,4r,5r,6s)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1[C@@H](CO)O[C@@H](O[C@@H]2[C@H](O[C@H](O)[C@H](O)[C@H]2O)CO)[C@H](O)[C@H]1O FYGDTMLNYKFZSV-WFYNLLPOSA-N 0.000 claims 1
- 239000004909 Moisturizer Substances 0.000 claims 1
- 230000001333 moisturizer Effects 0.000 claims 1
- 239000002304 perfume Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 abstract description 6
- 238000010586 diagram Methods 0.000 abstract 1
- 238000009472 formulation Methods 0.000 description 24
- 239000000047 product Substances 0.000 description 19
- 229920001503 Glucan Polymers 0.000 description 12
- 239000000306 component Substances 0.000 description 12
- 239000007788 liquid Substances 0.000 description 12
- 210000001724 microfibril Anatomy 0.000 description 8
- 229930195733 hydrocarbon Natural products 0.000 description 6
- 150000002430 hydrocarbons Chemical class 0.000 description 6
- 239000007791 liquid phase Substances 0.000 description 6
- -1 pH regulators Substances 0.000 description 6
- 239000004215 Carbon black (E152) Substances 0.000 description 5
- 150000001875 compounds Chemical class 0.000 description 5
- 239000004615 ingredient Substances 0.000 description 5
- 239000000463 material Substances 0.000 description 5
- 235000015112 vegetable and seed oil Nutrition 0.000 description 5
- 125000002353 D-glucosyl group Chemical group C1([C@H](O)[C@@H](O)[C@H](O)[C@H](O1)CO)* 0.000 description 4
- 239000001913 cellulose Substances 0.000 description 4
- 229920002678 cellulose Polymers 0.000 description 4
- 238000000855 fermentation Methods 0.000 description 4
- 230000004151 fermentation Effects 0.000 description 4
- 229920000728 polyester Polymers 0.000 description 4
- 239000002904 solvent Substances 0.000 description 4
- WDQLRUYAYXDIFW-RWKIJVEZSA-N (2r,3r,4s,5r,6r)-4-[(2s,3r,4s,5r,6r)-3,5-dihydroxy-4-[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-6-[[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl]oxy-6-(hydroxymethyl)oxane-2,3,5-triol Chemical compound O[C@@H]1[C@@H](CO)O[C@@H](O)[C@H](O)[C@H]1O[C@H]1[C@H](O)[C@@H](O[C@H]2[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O2)O)[C@H](O)[C@@H](CO[C@H]2[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O2)O)O1 WDQLRUYAYXDIFW-RWKIJVEZSA-N 0.000 description 3
- 235000019489 Almond oil Nutrition 0.000 description 3
- 241001672694 Citrus reticulata Species 0.000 description 3
- 239000004386 Erythritol Substances 0.000 description 3
- UNXHWFMMPAWVPI-UHFFFAOYSA-N Erythritol Natural products OCC(O)C(O)CO UNXHWFMMPAWVPI-UHFFFAOYSA-N 0.000 description 3
- 240000004808 Saccharomyces cerevisiae Species 0.000 description 3
- 235000014680 Saccharomyces cerevisiae Nutrition 0.000 description 3
- 239000008168 almond oil Substances 0.000 description 3
- 125000004432 carbon atom Chemical group C* 0.000 description 3
- 238000007385 chemical modification Methods 0.000 description 3
- 235000019868 cocoa butter Nutrition 0.000 description 3
- 229940110456 cocoa butter Drugs 0.000 description 3
- 230000000052 comparative effect Effects 0.000 description 3
- UNXHWFMMPAWVPI-ZXZARUISSA-N erythritol Chemical compound OC[C@H](O)[C@H](O)CO UNXHWFMMPAWVPI-ZXZARUISSA-N 0.000 description 3
- 229940009714 erythritol Drugs 0.000 description 3
- 235000019414 erythritol Nutrition 0.000 description 3
- 125000002791 glucosyl group Chemical group C1([C@H](O)[C@@H](O)[C@H](O)[C@H](O1)CO)* 0.000 description 3
- 239000003960 organic solvent Substances 0.000 description 3
- 239000002245 particle Substances 0.000 description 3
- 238000000926 separation method Methods 0.000 description 3
- 239000007921 spray Substances 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- 229940025703 topical product Drugs 0.000 description 3
- 239000008158 vegetable oil Substances 0.000 description 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
- 235000008733 Citrus aurantifolia Nutrition 0.000 description 2
- 229920002558 Curdlan Polymers 0.000 description 2
- 239000001879 Curdlan Substances 0.000 description 2
- 102000011782 Keratins Human genes 0.000 description 2
- 108010076876 Keratins Proteins 0.000 description 2
- 241001558929 Sclerotium <basidiomycota> Species 0.000 description 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
- 235000011941 Tilia x europaea Nutrition 0.000 description 2
- 240000006909 Tilia x europaea Species 0.000 description 2
- 239000000443 aerosol Substances 0.000 description 2
- 239000007864 aqueous solution Substances 0.000 description 2
- 239000003125 aqueous solvent Substances 0.000 description 2
- 210000004027 cell Anatomy 0.000 description 2
- 210000002421 cell wall Anatomy 0.000 description 2
- 239000003240 coconut oil Substances 0.000 description 2
- 235000019864 coconut oil Nutrition 0.000 description 2
- 230000003750 conditioning effect Effects 0.000 description 2
- 229940078035 curdlan Drugs 0.000 description 2
- 235000019316 curdlan Nutrition 0.000 description 2
- GHVNFZFCNZKVNT-UHFFFAOYSA-N decanoic acid Chemical compound CCCCCCCCCC(O)=O GHVNFZFCNZKVNT-UHFFFAOYSA-N 0.000 description 2
- 235000014113 dietary fatty acids Nutrition 0.000 description 2
- 239000003974 emollient agent Substances 0.000 description 2
- 239000000194 fatty acid Substances 0.000 description 2
- 229930195729 fatty acid Natural products 0.000 description 2
- 150000004665 fatty acids Chemical class 0.000 description 2
- 239000012467 final product Substances 0.000 description 2
- 229910052731 fluorine Inorganic materials 0.000 description 2
- 235000011389 fruit/vegetable juice Nutrition 0.000 description 2
- 239000000499 gel Substances 0.000 description 2
- 238000010438 heat treatment Methods 0.000 description 2
- 229920001519 homopolymer Polymers 0.000 description 2
- 239000004571 lime Substances 0.000 description 2
- 230000000813 microbial effect Effects 0.000 description 2
- WWZKQHOCKIZLMA-UHFFFAOYSA-N octanoic acid Chemical compound CCCCCCCC(O)=O WWZKQHOCKIZLMA-UHFFFAOYSA-N 0.000 description 2
- 239000000523 sample Substances 0.000 description 2
- 230000001953 sensory effect Effects 0.000 description 2
- 238000010008 shearing Methods 0.000 description 2
- 239000002002 slurry Substances 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 238000003860 storage Methods 0.000 description 2
- 239000000758 substrate Substances 0.000 description 2
- 239000000725 suspension Substances 0.000 description 2
- LADGBHLMCUINGV-UHFFFAOYSA-N tricaprin Chemical compound CCCCCCCCCC(=O)OCC(OC(=O)CCCCCCCCC)COC(=O)CCCCCCCCC LADGBHLMCUINGV-UHFFFAOYSA-N 0.000 description 2
- 239000001993 wax Substances 0.000 description 2
- DBTMGCOVALSLOR-DEVYUCJPSA-N (2s,3r,4s,5r,6r)-4-[(2s,3r,4s,5r,6r)-3,5-dihydroxy-6-(hydroxymethyl)-4-[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-6-(hydroxymethyl)oxane-2,3,5-triol Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](CO)O[C@H](O)[C@@H]2O)O)O[C@H](CO)[C@H]1O DBTMGCOVALSLOR-DEVYUCJPSA-N 0.000 description 1
- 241000589158 Agrobacterium Species 0.000 description 1
- 241000195940 Bryophyta Species 0.000 description 1
- 235000005273 Canna coccinea Nutrition 0.000 description 1
- 240000008555 Canna flaccida Species 0.000 description 1
- 239000005632 Capric acid (CAS 334-48-5) Substances 0.000 description 1
- 239000005635 Caprylic acid (CAS 124-07-2) Substances 0.000 description 1
- 240000004385 Centaurea cyanus Species 0.000 description 1
- 235000005940 Centaurea cyanus Nutrition 0.000 description 1
- 240000000425 Chaenomeles speciosa Species 0.000 description 1
- 235000005078 Chaenomeles speciosa Nutrition 0.000 description 1
- 235000005979 Citrus limon Nutrition 0.000 description 1
- 240000004307 Citrus medica Species 0.000 description 1
- 244000131522 Citrus pyriformis Species 0.000 description 1
- 240000002319 Citrus sinensis Species 0.000 description 1
- 235000005976 Citrus sinensis Nutrition 0.000 description 1
- 244000114646 Citrus x jambhiri Species 0.000 description 1
- 235000016904 Citrus x jambhiri Nutrition 0.000 description 1
- 240000000560 Citrus x paradisi Species 0.000 description 1
- 241000333459 Citrus x tangelo Species 0.000 description 1
- 240000008067 Cucumis sativus Species 0.000 description 1
- 235000010799 Cucumis sativus var sativus Nutrition 0.000 description 1
- 150000000780 D-glucose derivatives Chemical class 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- YCKRFDGAMUMZLT-UHFFFAOYSA-N Fluorine atom Chemical compound [F] YCKRFDGAMUMZLT-UHFFFAOYSA-N 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- 241000222684 Grifola Species 0.000 description 1
- 235000019487 Hazelnut oil Nutrition 0.000 description 1
- 229920002488 Hemicellulose Polymers 0.000 description 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 description 1
- 241001598113 Laminaria digitata Species 0.000 description 1
- 229920001543 Laminarin Polymers 0.000 description 1
- 239000005717 Laminarin Substances 0.000 description 1
- 229920001491 Lentinan Polymers 0.000 description 1
- 241000222418 Lentinus Species 0.000 description 1
- 235000019493 Macadamia oil Nutrition 0.000 description 1
- 241000220317 Rosa Species 0.000 description 1
- 241000221696 Sclerotinia sclerotiorum Species 0.000 description 1
- 235000003434 Sesamum indicum Nutrition 0.000 description 1
- 244000000231 Sesamum indicum Species 0.000 description 1
- 229910018557 Si O Inorganic materials 0.000 description 1
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical group [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 description 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 description 1
- 235000019486 Sunflower oil Nutrition 0.000 description 1
- 235000018936 Vitellaria paradoxa Nutrition 0.000 description 1
- 241001135917 Vitellaria paradoxa Species 0.000 description 1
- 208000034699 Vitreous floaters Diseases 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 230000002378 acidificating effect Effects 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 150000001298 alcohols Chemical class 0.000 description 1
- OENHQHLEOONYIE-UKMVMLAPSA-N all-trans beta-carotene Natural products CC=1CCCC(C)(C)C=1/C=C/C(/C)=C/C=C/C(/C)=C/C=C/C=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C OENHQHLEOONYIE-UKMVMLAPSA-N 0.000 description 1
- 230000003255 anti-acne Effects 0.000 description 1
- 230000003712 anti-aging effect Effects 0.000 description 1
- 230000001166 anti-perspirative effect Effects 0.000 description 1
- 239000003213 antiperspirant Substances 0.000 description 1
- 239000010477 apricot oil Substances 0.000 description 1
- 239000012736 aqueous medium Substances 0.000 description 1
- 239000003212 astringent agent Substances 0.000 description 1
- 125000004429 atom Chemical group 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 239000008163 avocado oil Substances 0.000 description 1
- 235000021302 avocado oil Nutrition 0.000 description 1
- 239000002199 base oil Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- TUPZEYHYWIEDIH-WAIFQNFQSA-N beta-carotene Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CCCC1(C)C)C=CC=C(/C)C=CC2=CCCCC2(C)C TUPZEYHYWIEDIH-WAIFQNFQSA-N 0.000 description 1
- 239000011648 beta-carotene Substances 0.000 description 1
- 235000013734 beta-carotene Nutrition 0.000 description 1
- 229960002747 betacarotene Drugs 0.000 description 1
- 239000011230 binding agent Substances 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 239000000828 canola oil Substances 0.000 description 1
- 235000019519 canola oil Nutrition 0.000 description 1
- 150000001721 carbon Chemical class 0.000 description 1
- 239000004359 castor oil Substances 0.000 description 1
- 235000019438 castor oil Nutrition 0.000 description 1
- 210000001072 colon Anatomy 0.000 description 1
- 239000013068 control sample Substances 0.000 description 1
- 235000005687 corn oil Nutrition 0.000 description 1
- 239000002285 corn oil Substances 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 239000002781 deodorant agent Substances 0.000 description 1
- 238000001212 derivatisation Methods 0.000 description 1
- 238000007865 diluting Methods 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000009144 enzymatic modification Effects 0.000 description 1
- 230000032050 esterification Effects 0.000 description 1
- 238000005886 esterification reaction Methods 0.000 description 1
- 150000002148 esters Chemical class 0.000 description 1
- 150000002170 ethers Chemical class 0.000 description 1
- 238000001704 evaporation Methods 0.000 description 1
- 230000008020 evaporation Effects 0.000 description 1
- 150000002191 fatty alcohols Chemical class 0.000 description 1
- 239000000945 filler Substances 0.000 description 1
- 239000011737 fluorine Substances 0.000 description 1
- 125000001153 fluoro group Chemical group F* 0.000 description 1
- 239000006260 foam Substances 0.000 description 1
- 238000005187 foaming Methods 0.000 description 1
- 239000003205 fragrance Substances 0.000 description 1
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 description 1
- 239000008169 grapeseed oil Substances 0.000 description 1
- 239000000118 hair dye Substances 0.000 description 1
- 239000010468 hazelnut oil Substances 0.000 description 1
- 229910052739 hydrogen Inorganic materials 0.000 description 1
- 239000001257 hydrogen Substances 0.000 description 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 229940119170 jojoba wax Drugs 0.000 description 1
- 229940115286 lentinan Drugs 0.000 description 1
- 239000010469 macadamia oil Substances 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 238000000691 measurement method Methods 0.000 description 1
- 238000002844 melting Methods 0.000 description 1
- 230000008018 melting Effects 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 230000003020 moisturizing effect Effects 0.000 description 1
- 235000011929 mousse Nutrition 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 229960002446 octanoic acid Drugs 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 238000009928 pasteurization Methods 0.000 description 1
- 239000001814 pectin Substances 0.000 description 1
- 229920001277 pectin Polymers 0.000 description 1
- 235000010987 pectin Nutrition 0.000 description 1
- 239000003208 petroleum Substances 0.000 description 1
- 239000005426 pharmaceutical component Substances 0.000 description 1
- 125000004437 phosphorous atom Chemical group 0.000 description 1
- 230000002335 preservative effect Effects 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 239000003380 propellant Substances 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 239000012264 purified product Substances 0.000 description 1
- 150000003254 radicals Chemical class 0.000 description 1
- 229940057910 shea butter Drugs 0.000 description 1
- 229910052710 silicon Inorganic materials 0.000 description 1
- LIVNPJMFVYWSIS-UHFFFAOYSA-N silicon monoxide Inorganic materials [Si-]#[O+] LIVNPJMFVYWSIS-UHFFFAOYSA-N 0.000 description 1
- 229920002545 silicone oil Polymers 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 239000003549 soybean oil Substances 0.000 description 1
- 235000012424 soybean oil Nutrition 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 229910052717 sulfur Inorganic materials 0.000 description 1
- 239000011593 sulfur Substances 0.000 description 1
- 239000002600 sunflower oil Substances 0.000 description 1
- 239000006228 supernatant Substances 0.000 description 1
- 239000000829 suppository Substances 0.000 description 1
- 230000008719 thickening Effects 0.000 description 1
- 239000002562 thickening agent Substances 0.000 description 1
- 150000003626 triacylglycerols Chemical class 0.000 description 1
- 235000019871 vegetable fat Nutrition 0.000 description 1
- 230000009278 visceral effect Effects 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- 230000002087 whitening effect Effects 0.000 description 1
- OENHQHLEOONYIE-JLTXGRSLSA-N β-Carotene Chemical compound CC=1CCCC(C)(C)C=1\C=C\C(\C)=C\C=C\C(\C)=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C OENHQHLEOONYIE-JLTXGRSLSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/0241—Containing particulates characterized by their shape and/or structure
- A61K8/027—Fibers; Fibrils
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
- A61K8/06—Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/02—Preparations for cleaning the hair
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0024—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Glucans; (beta-1,3)-D-Glucans, e.g. paramylon, coriolan, sclerotan, pachyman, callose, scleroglucan, schizophyllan, laminaran, lentinan or curdlan; (beta-1,6)-D-Glucans, e.g. pustulan; (beta-1,4)-D-Glucans; (beta-1,3)(beta-1,4)-D-Glucans, e.g. lichenan; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L97/00—Compositions of lignin-containing materials
- C08L97/02—Lignocellulosic material, e.g. wood, straw or bagasse
Abstract
Description
本出願は、2019年2月1日に出願された「CITRUS FIBERS AND SCLEROGLUCAN EMULSIONS AND THE USE THEREOF IN PERSONAL CARE APPLICATIONS」と題された米国特許仮出願第62/799,962号、及び2019年3月22日に出願された「CITRUS FIBERS AND SCLEROGLUCAN EMULSIONS AND THE USE THEREOF IN PERSONAL CARE APPLICATIONS」と題された米国特許仮出願第62/822,359号の利益を主張するものであり、これらのそれぞれは、参照によりその全体が本明細書に組み込まれる。
本発明は、柑橘類繊維及び1,3-β-D-グルカンのブレンドに関し、水溶液又はエマルションの生成におけるこれらのブレンドの使用、及びパーソナルケアのための局所製剤の製造におけるそれらの使用に関する。
a)柑橘類繊維及び1,3-β-D-グルカンのブレンドを提供する工程と、
b)ブレンドを水に添加し、混合して水相を形成する工程と、
c)水相中に油を分散させて、エマルションを得る工程と、を含む。
任意に、均質化工程が、工程c)の前及び/又は後に含まれ得る。
好ましくは、本発明において使用される1,3-β-D-グルカンは、スクレログルカンである。
柑橘類繊維
1,3-β-D-グルカンは、β-(1,3)様式で結合したD-グルコース残基の骨格を特徴とする多糖類であり、種々の1,3-β-D-グルカンは、それらの側基及び分子量に関して互いに構造的に異なる。例えば、カードランは、β-(1,3)-Dグルコース骨格のみからなるが、シゾフィラン、スクレログルカン及び酵母グルカンは、β-(1,6)-グリコシル側鎖を含有する。典型的には、1,3-β-D-グルカンは微生物発酵によって生成され、発酵ブロスは、通常は低温殺菌された後に、直接、又は希釈若しくは精製された形態で使用される(例えば、米国特許第3,301,848号を参照)。1,3-β-D-グルカンは、精製形態で、又は1,3-β-D-グルカンと発酵残渣との混合物として使用され得る。本発明の目的のために、使用される1,3-β-D-グルカンは、好ましくは精製されて、1,3-β-D-グルカン以外の発酵ブロスの微生物細胞及び/又は水溶性成分の量及び活性を低減及び中和する。国際公開第2009/062561号は、そのような高純度1,3-β-D-グルカンの製造方法を開示している。
エマルション
1.水相
2.油相
ブレンド
局所製剤
エマルション及び局所製剤の製造プロセス
a)柑橘類繊維及び1,3-β-D-グルカンのブレンドを提供する工程と、
b)ブレンドを水に添加し、混合して水相を形成する工程と、
c)水相中に油を分散させて、エマルションを得る工程と、を含むプロセスによって形成され得る。
出発物質:
使用した柑橘類繊維は、Cargill Incorporatedから入手したCitriTex-ACFであった。あるいは、柑橘類繊維は、例えば、国際公開第2012/016190号及び国際公開第2017/019752号に記載されているような既知のプロトコルを使用して調製されてもよい。
1.Clark Lubs緩衝液(試料50g+緩衝液50g)で2重量%の繊維のスラリーを希釈することによって、1重量%の繊維懸濁液を調製した。
2.速度400rpmで磁気撹拌機(30分)を用いて分散させた。
3.遠心管(キャップを有する)を風袋引きした(W0)。
4.繊維懸濁液を2つの遠心管に迅速に移し、蓋をした。
5.正確に同じ重量2×2(+/-0.1g)を有するようにチューブを平衡化した(W1)。
6.管を、室温で3000gで10分間遠心分離した。
7.ピペットによって上清を除去し、秤量した(W2)。
8.充填した材料を秤量した(W3)。
9.水保持容量は以下のように計算される:WHC=(W3-W0)/(W1-W0)*100
本発明のブレンドで調製された試料についての水保持容量は、対照製剤よりも優れた水保持容量を明確に示す。この特性は、パーソナルケア用途において非常に有利であり、望ましい。
実施例1
実施例2
Claims (22)
- 水相及び油相を含むエマルションであって、柑橘類繊維及び1,3-β-D-グルカンを含む、エマルション。
- 前記柑橘類繊維及び1,3-β-D-グルカンが、90:10~10:90、より好ましくは80:20~20:80、又は70:30~30:70、又は60:40~40:60、又は50:50の比である、請求項1に記載のエマルション。
- 前記エマルション中の前記水相の量が、30重量%~99重量%、又は40重量%~60重量%、又は60重量%~80重量%、又は70重量%~90重量%である、請求項1又は2に記載のエマルション。
- 前記エマルション中の前記油相の量が、0.1重量%~70重量%、又は5重量%~55重量%、又は10重量%~40重量%、又は10重量%~30重量%である、請求項1~3のいずれか一項に記載のエマルション。
- 前記柑橘類繊維及び/又は1,3-β-D-グルカンが、前記水相、前記油相、又はその両方中に分散している、請求項1~4のいずれか一項に記載のエマルション。
- 前記油相が、天然油、水素添加油、トリグリセリド、菜種油、又は非天然油を含む、請求項1~5のいずれか一項に記載のエマルション。
- 防腐剤、塩、ビタミン、乳化剤、品質改良剤、栄養素、微量栄養素、糖、タンパク質、多糖類、ポリオール、グルコース、スクロース、グリセロール、ソルビトール、pH調整剤、皮膚軟化剤、染料、顔料、皮膚活性物質、ワックス又はシリコーンからなる群から選択される少なくとも1つの更なる成分を更に含む、請求項1~6のいずれか一項に記載のエマルション。
- 前記柑橘類繊維及び1,3-β-D-グルカンが、前記エマルションを製造するために使用される場合、ブレンド、好ましくは共処理ブレンドの形態である、請求項1~7のいずれか一項に記載のエマルション。
- 前記エマルション中の前記ブレンドの量が、0.1重量%~5重量%、好ましくは0.2重量%~3重量%、より好ましくは0.3重量%~3重量%である、請求項8に記載のエマルション。
- 前記柑橘類繊維及び/又は1,3-β-D-グルカンが、前記水相、前記油相、又はその両方中に分散している、請求項1~9のいずれか一項に記載のエマルション。
- 請求項1~10のいずれか一項に記載のエマルションを含む、局所製剤。
- 化粧品、クリーム、香油、石鹸、日焼け止め、保湿剤、ローション、シャンプー、ヘアスタイリング製品、リーブオンヘアジェル、コンディショナ、ヘアケア製品、頭皮トリートメント、又は皮膚トリートメントである、請求項11に記載の局所製剤。
- 柑橘類繊維及び1,3-β-D-グルカンを含む乾燥ブレンドであって、好ましくは前記乾燥ブレンドが、共処理ブレンドである、乾燥ブレンド。
- 前記ブレンド中の前記柑橘類繊維の濃度が、25重量%~99重量%、又は35重量%~95重量%、又は55重量%~85重量%であり、かつ、前記ブレンド中の前記1,3-β-D-グルカンの濃度が、0.1重量%~75重量%、又は1重量%~65重量%、又は5重量%~55重量%、又は10重量%~55重量%である、請求項13に記載の乾燥ブレンド。
- 前記柑橘類繊維及び1,3-β-D-グルカンが、90:10~10:90、より好ましくは80:20~20:80、又は70:30~30:70、又は60:40~40:60、又は50:50の比である、請求項13に記載の乾燥ブレンド。
- 請求項13、14、又は15のいずれか一項に記載のブレンドを含む水性混合物であって、任意に、前記混合物の粘度が、3~300,000Cpsである、水性混合物。
- 請求項16に記載の水性混合物を含む、局所製剤。
- パーソナルケア製品である、請求項11又は17に記載の局所製剤。
- 柑橘類繊維及び1,3-β-D-グルカンのエマルションを生産するためのプロセスであって、
a)柑橘類繊維及び1,3-β-D-グルカンのブレンドを提供する工程と、
b)前記ブレンドを水に添加し、混合して水相を形成する工程と、
c)前記水相中に油を分散させて、エマルションを得る工程と、を含み、
任意に、前記プロセスが、工程c)の前及び/又は後に均質化工程を更に含む、プロセス。 - 前記1,3-β-D-グルカンが、スクレログルカンである、請求項1~19のいずれか一項に記載のエマルション、局所製剤、乾燥ブレンド、水性混合物、又はプロセス。
- 水中油型エマルションである、請求項1~20のいずれか一項に記載のエマルション。
- パーソナルケア組成物を調製するための、請求項1~21のいずれか一項に記載の乾燥ブレンドの使用。
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201962799962P | 2019-02-01 | 2019-02-01 | |
US62/799,962 | 2019-02-01 | ||
US201962822359P | 2019-03-22 | 2019-03-22 | |
US62/822,359 | 2019-03-22 | ||
PCT/US2020/016413 WO2020160544A1 (en) | 2019-02-01 | 2020-02-03 | Citrus fibers and scleroglucan compositions and the use thereof in personal care applications |
Publications (1)
Publication Number | Publication Date |
---|---|
JP2022519127A true JP2022519127A (ja) | 2022-03-18 |
Family
ID=69771071
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2021544929A Pending JP2022519127A (ja) | 2019-02-01 | 2020-02-03 | 柑橘類繊維及びスクレログルカン組成物、並びにパーソナルケア用途におけるそれらの使用 |
Country Status (7)
Country | Link |
---|---|
US (1) | US20220105019A1 (ja) |
EP (1) | EP3917488A1 (ja) |
JP (1) | JP2022519127A (ja) |
KR (1) | KR20210125023A (ja) |
CN (1) | CN113490479A (ja) |
BR (1) | BR112021015116A2 (ja) |
WO (1) | WO2020160544A1 (ja) |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3301848A (en) | 1962-10-30 | 1967-01-31 | Pillsbury Co | Polysaccharides and methods for production thereof |
US5567424A (en) * | 1994-06-10 | 1996-10-22 | Reliv International, Inc. | Fiber, antioxidant, herbal and enzyme supplemented beverage composition for human consumption |
US9629790B2 (en) * | 2002-11-06 | 2017-04-25 | Fiberstar, Inc | Stabilization of cosmetic compositions |
WO2007003391A1 (en) * | 2005-07-06 | 2007-01-11 | Cargill, Incorporated | Citrus fruit fibres in emulsions |
US20090087513A1 (en) * | 2007-10-01 | 2009-04-02 | Jay Satz | Fiber and fatty acid composition and method of making same |
CN104744605A (zh) | 2007-11-13 | 2015-07-01 | 卡吉尔公司 | 净化的β-(1,3)-D-葡聚糖的制备方法 |
CN103002755B (zh) * | 2010-07-30 | 2015-01-14 | 卡吉尔公司 | 改进柑橘纤维的性质的方法 |
US20130131012A1 (en) * | 2010-07-30 | 2013-05-23 | Cargill, Incorporated | Process for obtaining citrus fiber from citrus pulp |
US8697041B2 (en) * | 2010-08-10 | 2014-04-15 | Conopco, Inc. | Anti-dandruff compositions with citrus fibers |
AU2013209799B2 (en) | 2012-01-20 | 2016-10-13 | Cargill, Incorporated | Process for obtaining citrus fiber from citrus peel |
US9526925B2 (en) * | 2012-05-17 | 2016-12-27 | Edgewell Personal Care Brands, Llc | Viscous alcohol-containing sunscreen compositions |
KR20150107288A (ko) * | 2014-03-14 | 2015-09-23 | 코웨이 주식회사 | 유화제를 함유하지 않는 유화 화장료 조성물 |
CA2992310A1 (en) | 2015-07-30 | 2017-02-02 | Cargill, Incorporated | Dry citrus fibers and uses thereof |
MX2018001111A (es) | 2015-07-31 | 2018-07-06 | Cargill Inc | Fibras citricas con caracteristicas de union al agua optimizadas. |
MX2018016251A (es) | 2016-07-08 | 2019-05-30 | Cargill Inc | Dispersion que contiene fibras citricas. |
CN107712539A (zh) * | 2016-08-11 | 2018-02-23 | 张景娜 | 一种混合膳食纤维泡腾片 |
CN107212225A (zh) * | 2017-06-02 | 2017-09-29 | 陈玉霞 | 一种用于瘦身的玫瑰茄固体饮料及其制备方法 |
-
2020
- 2020-02-03 KR KR1020217027545A patent/KR20210125023A/ko unknown
- 2020-02-03 BR BR112021015116-8A patent/BR112021015116A2/pt unknown
- 2020-02-03 US US17/427,707 patent/US20220105019A1/en active Pending
- 2020-02-03 CN CN202080016373.1A patent/CN113490479A/zh active Pending
- 2020-02-03 WO PCT/US2020/016413 patent/WO2020160544A1/en unknown
- 2020-02-03 EP EP20709830.2A patent/EP3917488A1/en active Pending
- 2020-02-03 JP JP2021544929A patent/JP2022519127A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
EP3917488A1 (en) | 2021-12-08 |
US20220105019A1 (en) | 2022-04-07 |
CN113490479A (zh) | 2021-10-08 |
WO2020160544A1 (en) | 2020-08-06 |
BR112021015116A2 (pt) | 2021-09-28 |
KR20210125023A (ko) | 2021-10-15 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MX2015001225A (es) | Composiciones acuosas estabilizadas de fases multiples. | |
CN105902408B (zh) | 含有褐藻和红藻精华的化妆品组合物 | |
JP5576080B2 (ja) | β−グルカン含有組成物 | |
FR2769836A1 (fr) | Utilisation de nanofibrilles de cellulose essentiellement amorphes associees a au moins un compose organique polyhydroxyle dans des formulations cosmetiques | |
US20120245234A1 (en) | Cosmetic and dermatologic composition and uses thereof | |
CN111417380A (zh) | 个人护理产品 | |
CN111971069A (zh) | 用于化妆品和健康用途的粉末组合物 | |
EP2863999B1 (fr) | Composition cosmétique des particules d'aérogel de silice hydrophobe et un polymère à motif sucre | |
JPH10279466A (ja) | 外用剤 | |
JP2022526728A (ja) | 高油含有量の局所パーソナルケア製品 | |
FR3090341A1 (fr) | Composition comprenant un corps gras, un polymere peg, un diol et un polysaccharide | |
WO2016195142A1 (ko) | 모링가 추출물을 포함하는 나노에멀젼 천연 미용 조성물의 제조방법 | |
US20200022886A1 (en) | Low density, stable foam for topical application | |
JP2022519127A (ja) | 柑橘類繊維及びスクレログルカン組成物、並びにパーソナルケア用途におけるそれらの使用 | |
JPS6366107A (ja) | 乳化型化粧料 | |
CN110368329B (zh) | 一种不含硅油的均相护理组合物 | |
EP4072506A1 (de) | Mikroplastikfreie zusammensetzung | |
JP4150280B2 (ja) | 高内水相油中水型乳化化粧料 | |
JP3074591B2 (ja) | 化粧料 | |
WO2023192583A1 (en) | A method of tightening and smoothing the skin in personal care products | |
Garcia et al. | Thickening agents | |
WO2023064836A1 (en) | Personal care pre-emulsion mixture | |
KR102333145B1 (ko) | 스피큘을 포함하는 피부 보습도 개선을 위한 화장품 조성물 및 이의 제조 방법 | |
WO2023192581A1 (en) | Skin tightening and smoothing personal care products | |
CN113975198B (zh) | 一种免水洗发慕斯 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
RD03 | Notification of appointment of power of attorney |
Free format text: JAPANESE INTERMEDIATE CODE: A7423 Effective date: 20211012 |
|
RD04 | Notification of resignation of power of attorney |
Free format text: JAPANESE INTERMEDIATE CODE: A7424 Effective date: 20211130 |
|
A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20230131 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20240109 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20240405 |