JP2022517809A5 - - Google Patents
Info
- Publication number
- JP2022517809A5 JP2022517809A5 JP2021541292A JP2021541292A JP2022517809A5 JP 2022517809 A5 JP2022517809 A5 JP 2022517809A5 JP 2021541292 A JP2021541292 A JP 2021541292A JP 2021541292 A JP2021541292 A JP 2021541292A JP 2022517809 A5 JP2022517809 A5 JP 2022517809A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- sequence number
- amino acid
- chain variable
- variable region
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962794064P | 2019-01-18 | 2019-01-18 | |
| US62/794,064 | 2019-01-18 | ||
| PCT/CA2020/050042 WO2020146946A1 (en) | 2019-01-18 | 2020-01-16 | Lilrb3-binding molecules and uses therefor |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022517809A JP2022517809A (ja) | 2022-03-10 |
| JP2022517809A5 true JP2022517809A5 (https=) | 2023-01-26 |
| JP7631203B2 JP7631203B2 (ja) | 2025-02-18 |
Family
ID=71612981
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021541292A Active JP7631203B2 (ja) | 2019-01-18 | 2020-01-16 | Ｌｉｌｒｂ３結合分子とその使用 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US12404327B2 (https=) |
| EP (1) | EP3911680A4 (https=) |
| JP (1) | JP7631203B2 (https=) |
| KR (1) | KR20210118116A (https=) |
| CN (1) | CN113454123A (https=) |
| AU (1) | AU2020209367A1 (https=) |
| BR (1) | BR112021014102A2 (https=) |
| CA (1) | CA3126295A1 (https=) |
| EA (1) | EA202192008A1 (https=) |
| IL (1) | IL284781A (https=) |
| MX (1) | MX2021008507A (https=) |
| SG (1) | SG11202107663UA (https=) |
| TW (1) | TWI852980B (https=) |
| WO (1) | WO2020146946A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7181438B2 (ja) * | 2019-08-06 | 2022-11-30 | アプリノイア セラピューティクス リミテッド | 病理学的タウ種に結合する抗体及びその使用 |
| EP4255451A4 (en) * | 2020-12-03 | 2025-01-01 | The Board Of Regents Of The University Of Texas System | Methods for identifying lilrb-blocking antibodies |
| CN115925941B (zh) * | 2022-06-08 | 2026-04-03 | 北京科诺信诚科技有限公司 | 靶向人lilrb4的纳米抗体及其应用 |
| WO2025231127A1 (en) * | 2024-05-02 | 2025-11-06 | The Regents Of The University Of California | Compositions and methods for intracellular antigen targeting with antibodies |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| US5859205A (en) | 1989-12-21 | 1999-01-12 | Celltech Limited | Humanised antibodies |
| EP1400536A1 (en) | 1991-06-14 | 2004-03-24 | Genentech Inc. | Method for making humanized antibodies |
| WO1994004679A1 (en) | 1991-06-14 | 1994-03-03 | Genentech, Inc. | Method for making humanized antibodies |
| AU2004297616B2 (en) | 2003-12-04 | 2008-12-18 | Xencor, Inc. | Methods of generating variant proteins with increased host string content and compositions thereof |
| WO2011091181A1 (en) | 2010-01-20 | 2011-07-28 | Tolerx, Inc. | Immunoregulation by anti-ilt5 antibodies and ilt5-binding antibody fragments |
| CA2787783A1 (en) | 2010-01-20 | 2011-07-28 | Tolerx, Inc. | Anti-ilt5 antibodies and ilt5-binding antibody fragments |
| CA2867444C (en) | 2012-03-16 | 2021-04-13 | University Health Network | Compositions containing soluble toso protein and uses thereof |
| US20150174203A1 (en) | 2012-05-30 | 2015-06-25 | Icahn School Of Medicine At Mount Sinai | Compositions And Methods For Modulating Pro-Inflammatory Immune Response |
| US9493561B2 (en) | 2013-07-03 | 2016-11-15 | University Health Network | Antibodies to Toso |
| CA2961439A1 (en) | 2014-11-05 | 2016-05-12 | Genentech, Inc. | Anti-fgfr2/3 antibodies and methods using same |
| US20180201676A1 (en) | 2015-02-11 | 2018-07-19 | University Health Network | Methods and compositions for modulating lilr proteins |
| US10882905B2 (en) | 2015-03-05 | 2021-01-05 | Ab2 Bio Sa | IL-18 binding protein (IL-18BP) and antibodies in inflammatory diseases |
| CA2977544C (en) | 2015-03-06 | 2023-12-19 | The Board Of Regents Of The University Of Texas System | Anti-lilrb antibodies and their use in detecting and treating cancer |
| WO2018119425A2 (en) * | 2016-12-22 | 2018-06-28 | Icahn School Of Medicine At Mount Sinai | Anti-lilrb3 antibodies and methods of use thereof |
-
2020
- 2020-01-16 CA CA3126295A patent/CA3126295A1/en active Pending
- 2020-01-16 WO PCT/CA2020/050042 patent/WO2020146946A1/en not_active Ceased
- 2020-01-16 JP JP2021541292A patent/JP7631203B2/ja active Active
- 2020-01-16 CN CN202080015060.4A patent/CN113454123A/zh active Pending
- 2020-01-16 TW TW109101527A patent/TWI852980B/zh active
- 2020-01-16 SG SG11202107663UA patent/SG11202107663UA/en unknown
- 2020-01-16 KR KR1020217026164A patent/KR20210118116A/ko not_active Ceased
- 2020-01-16 EA EA202192008A patent/EA202192008A1/ru unknown
- 2020-01-16 BR BR112021014102-2A patent/BR112021014102A2/pt unknown
- 2020-01-16 AU AU2020209367A patent/AU2020209367A1/en active Pending
- 2020-01-16 US US17/421,705 patent/US12404327B2/en active Active
- 2020-01-16 EP EP20741290.9A patent/EP3911680A4/en active Pending
- 2020-01-16 MX MX2021008507A patent/MX2021008507A/es unknown
-
2021
- 2021-07-12 IL IL284781A patent/IL284781A/en unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US20240425617A1 (en) | Method of manufacturing bispecific antibodies, bispecific antibodies and therapeutic use of such antibodies | |
| JP2022517809A5 (https=) | ||
| US20260115254A1 (en) | Immune-cell targeted bispecific chimeric proteins and uses thereof | |
| TWI890481B (zh) | 雙特異性抗體 | |
| EP3577133A1 (en) | Targeted chimeric proteins and uses thereof | |
| US20140199299A1 (en) | Combination Therapies and Methods Using Anti-CD3 Modulating Agents and Anti-IL-6 Antagonists | |
| EP3833391A1 (en) | SIRP1alpha TARGETED CHIMERIC PROTEINS AND USES THEREOF | |
| MX2010013239A (es) | Inmunoglobulinas de dominio variable doble y usos de las mismas. | |
| JP2019521647A5 (https=) | ||
| TW200950805A (en) | Dual variable domain immunoglobulins and uses thereof | |
| HRP20220918T1 (hr) | Anti-transtiretinska antitijela | |
| MX2014008101A (es) | Proteinas de union especificas duales dirigidas contra il-13 y/o il-17. | |
| KR20240099223A (ko) | 항원 결합 폴리펩티드, 항원 결합 폴리펩티드 복합체 및 이의 사용 방법 | |
| US12410225B2 (en) | Modulation of dendritic cell lineages | |
| JP2022517441A (ja) | Ｂｔｌａ抗体 | |
| US20240199714A1 (en) | Il-2 based constructs | |
| JP2022528005A5 (https=) | ||
| JP2022522815A5 (https=) | ||
| TW201734041A (zh) | 抗ｉｌ-１７ｃ抗體 | |
| TWI862565B (zh) | 雙特異性抗體 | |
| RS66193B1 (sr) | Anti-pd-1 antitela | |
| JP2024544936A5 (https=) | ||
| CA3151928A1 (en) | Pd-l1 targeted chimeric proteins and uses thereof | |
| SG194362A1 (en) | Composition for treating disease | |
| JP2016512525A5 (https=) |