MX2021008507A - Moleculas que se unen al receptor leucocitario similar a inmunoglobulina subfamilia b miembro 3 (lilrb3) y usos para las mismas. - Google Patents

Moleculas que se unen al receptor leucocitario similar a inmunoglobulina subfamilia b miembro 3 (lilrb3) y usos para las mismas.

Info

Publication number
MX2021008507A
MX2021008507A MX2021008507A MX2021008507A MX2021008507A MX 2021008507 A MX2021008507 A MX 2021008507A MX 2021008507 A MX2021008507 A MX 2021008507A MX 2021008507 A MX2021008507 A MX 2021008507A MX 2021008507 A MX2021008507 A MX 2021008507A
Authority
MX
Mexico
Prior art keywords
lilrb3
binding molecules
uses therefor
antibodies
pharmaceutical compositions
Prior art date
Application number
MX2021008507A
Other languages
English (en)
Inventor
Jacqueline M Mason
Mark R Bray
Richard Brokx
Original Assignee
Univ Health Network
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Health Network filed Critical Univ Health Network
Publication of MX2021008507A publication Critical patent/MX2021008507A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Abstract

La invención proporciona novedosos anticuerpos anti- LILRB3, composiciones farmacéuticas que comprenden los anticuerpos y métodos terapéuticos de uso de los anticuerpos y composiciones farmacéuticas para el tratamiento de enfermedades tales como cáncer, enfermedades autoinmunitarias o inflamación alérgica. Esta invención también puede usarse para modular la diferenciación de osteoclastos.
MX2021008507A 2019-01-18 2020-01-16 Moleculas que se unen al receptor leucocitario similar a inmunoglobulina subfamilia b miembro 3 (lilrb3) y usos para las mismas. MX2021008507A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962794064P 2019-01-18 2019-01-18
PCT/CA2020/050042 WO2020146946A1 (en) 2019-01-18 2020-01-16 Lilrb3-binding molecules and uses therefor

Publications (1)

Publication Number Publication Date
MX2021008507A true MX2021008507A (es) 2021-09-21

Family

ID=71612981

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2021008507A MX2021008507A (es) 2019-01-18 2020-01-16 Moleculas que se unen al receptor leucocitario similar a inmunoglobulina subfamilia b miembro 3 (lilrb3) y usos para las mismas.

Country Status (14)

Country Link
US (1) US20220089723A1 (es)
EP (1) EP3911680A4 (es)
JP (1) JP2022517809A (es)
KR (1) KR20210118116A (es)
CN (1) CN113454123A (es)
AU (1) AU2020209367A1 (es)
BR (1) BR112021014102A2 (es)
CA (1) CA3126295A1 (es)
EA (1) EA202192008A1 (es)
IL (1) IL284781A (es)
MX (1) MX2021008507A (es)
SG (1) SG11202107663UA (es)
TW (1) TW202031685A (es)
WO (1) WO2020146946A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI780464B (zh) * 2019-08-06 2022-10-11 香港商新旭生技股份有限公司 結合至病理性ｔａｕ種類之抗體及其用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011091177A1 (en) * 2010-01-20 2011-07-28 Tolerx, Inc. Anti-ilt5 antibodies and ilt5-binding antibody fragments
WO2011091181A1 (en) * 2010-01-20 2011-07-28 Tolerx, Inc. Immunoregulation by anti-ilt5 antibodies and ilt5-binding antibody fragments
US20180201676A1 (en) * 2015-02-11 2018-07-19 University Health Network Methods and compositions for modulating lilr proteins
JP2020511950A (ja) * 2016-12-22 2020-04-23 アイカーン スクール オブ メディスン アット マウント シナイ 抗ｌｉｌｒｂ３抗体およびその使用の方法

Also Published As

Publication number Publication date
WO2020146946A1 (en) 2020-07-23
IL284781A (en) 2021-08-31
AU2020209367A1 (en) 2021-08-19
SG11202107663UA (en) 2021-08-30
JP2022517809A (ja) 2022-03-10
EP3911680A4 (en) 2022-09-07
CA3126295A1 (en) 2020-07-23
CN113454123A (zh) 2021-09-28
KR20210118116A (ko) 2021-09-29
EP3911680A1 (en) 2021-11-24
US20220089723A1 (en) 2022-03-24
BR112021014102A2 (pt) 2021-09-21
EA202192008A1 (ru) 2021-10-21
TW202031685A (zh) 2020-09-01

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