JP2016512525A5 - - Google Patents

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Publication number
JP2016512525A5
JP2016512525A5 JP2016501297A JP2016501297A JP2016512525A5 JP 2016512525 A5 JP2016512525 A5 JP 2016512525A5 JP 2016501297 A JP2016501297 A JP 2016501297A JP 2016501297 A JP2016501297 A JP 2016501297A JP 2016512525 A5 JP2016512525 A5 JP 2016512525A5
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JP
Japan
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chain variable
region
represented
variable region
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JP2016501297A
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English (en)
Japanese (ja)
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JP2016512525A (ja
JP6525432B2 (ja
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Priority claimed from PCT/US2014/023623 external-priority patent/WO2014159430A1/en
Publication of JP2016512525A publication Critical patent/JP2016512525A/ja
Publication of JP2016512525A5 publication Critical patent/JP2016512525A5/ja
Application granted granted Critical
Publication of JP6525432B2 publication Critical patent/JP6525432B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2016501297A 2013-03-14 2014-03-11 抗rankl抗体および使用方法 Expired - Fee Related JP6525432B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361786050P 2013-03-14 2013-03-14
US61/786,050 2013-03-14
PCT/US2014/023623 WO2014159430A1 (en) 2013-03-14 2014-03-11 Anti-rankl antibodies and methods of use

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2018142624A Division JP2018183176A (ja) 2013-03-14 2018-07-30 抗rankl抗体および使用方法

Publications (3)

Publication Number Publication Date
JP2016512525A JP2016512525A (ja) 2016-04-28
JP2016512525A5 true JP2016512525A5 (https=) 2017-04-13
JP6525432B2 JP6525432B2 (ja) 2019-06-05

Family

ID=51625166

Family Applications (2)

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JP2016501297A Expired - Fee Related JP6525432B2 (ja) 2013-03-14 2014-03-11 抗rankl抗体および使用方法
JP2018142624A Pending JP2018183176A (ja) 2013-03-14 2018-07-30 抗rankl抗体および使用方法

Family Applications After (1)

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JP2018142624A Pending JP2018183176A (ja) 2013-03-14 2018-07-30 抗rankl抗体および使用方法

Country Status (6)

Country Link
US (2) US10259878B2 (https=)
EP (1) EP2970462A4 (https=)
JP (2) JP6525432B2 (https=)
CN (1) CN105189551B (https=)
HK (1) HK1216754A1 (https=)
WO (1) WO2014159430A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10259878B2 (en) 2013-03-14 2019-04-16 Apexigen, Inc. Anti-RANKL antibodies and methods of use
TW201811976A (zh) 2016-08-08 2018-04-01 美商堤康那責任有限公司 用於散熱器之導熱聚合物組合物
CA3038850A1 (en) * 2016-10-28 2018-05-03 Eli Lilly And Company Anti-rankl antibodies and uses thereof
CN116514970B (zh) * 2017-10-27 2026-03-17 河北药明生物技术有限公司 靶向rankl的治疗性抗体
AU2019394364A1 (en) * 2018-12-05 2021-06-17 The Council Of The Queensland Institute Of Medical Research Rank antagonists and uses therefor
CN117062837A (zh) * 2021-05-12 2023-11-14 江苏恒瑞医药股份有限公司 特异性结合rankl和ngf的抗原结合分子及其医药用途

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9015198D0 (en) 1990-07-10 1990-08-29 Brien Caroline J O Binding substance
US5675063A (en) 1995-02-28 1997-10-07 Loyola University Of Chicago Immortalized rabbit hybridoma fusion partner
AU2001288342A1 (en) * 2000-08-21 2002-03-04 Smith Kline Beecham Corporation Anti-rank ligand monoclonal antibodies useful in treatment of rank ligand mediated disorders
MXPA03011270A (es) * 2001-06-06 2004-03-18 Immunex Corp Uso de antagonistas rank para tratar cancer.
US7462697B2 (en) 2004-11-08 2008-12-09 Epitomics, Inc. Methods for antibody engineering
US7429487B2 (en) 2005-07-05 2008-09-30 Epitomics, Inc. Fusion partner for production of monoclonal rabbit antibodies
WO2008088594A2 (en) * 2007-01-12 2008-07-24 Anaptysbio, Inc. Isolation of antibodies that cross-react and neutralize rankl orginating from multiple species
CA2687903C (en) * 2007-05-24 2016-09-13 Ablynx N.V. Amino acid sequences directed against rank-l and polypeptides comprising the same for the treatment of bone diseases and disorders
WO2011017294A1 (en) 2009-08-07 2011-02-10 Schering Corporation Human anti-rankl antibodies
US10259878B2 (en) 2013-03-14 2019-04-16 Apexigen, Inc. Anti-RANKL antibodies and methods of use
WO2015125922A1 (ja) * 2014-02-20 2015-08-27 国立大学法人東京大学 抗rankl抗体

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