JP2022517399A5 - - Google Patents

Info

Publication number
JP2022517399A5
JP2022517399A5 JP2021541187A JP2021541187A JP2022517399A5 JP 2022517399 A5 JP2022517399 A5 JP 2022517399A5 JP 2021541187 A JP2021541187 A JP 2021541187A JP 2021541187 A JP2021541187 A JP 2021541187A JP 2022517399 A5 JP2022517399 A5 JP 2022517399A5
Authority
JP
Japan
Prior art keywords
referred
sequence
sar
peptide ligand
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2021541187A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022517399A (ja
Filing date
Publication date
Priority claimed from GBGB1900530.5A external-priority patent/GB201900530D0/en
Application filed filed Critical
Publication of JP2022517399A publication Critical patent/JP2022517399A/ja
Publication of JP2022517399A5 publication Critical patent/JP2022517399A5/ja
Pending legal-status Critical Current

Links

JP2021541187A 2019-01-15 2020-01-15 Cd38に特異的な二環式ペプチドリガンド Pending JP2022517399A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1900530.5A GB201900530D0 (en) 2019-01-15 2019-01-15 Bicyclic peptide ligands specific for CD38
GB1900530.5 2019-01-15
PCT/GB2020/050074 WO2020148530A1 (en) 2019-01-15 2020-01-15 Bicyclic peptide ligands specific for cd38

Publications (2)

Publication Number Publication Date
JP2022517399A JP2022517399A (ja) 2022-03-08
JP2022517399A5 true JP2022517399A5 (enExample) 2023-01-25

Family

ID=65528178

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021541187A Pending JP2022517399A (ja) 2019-01-15 2020-01-15 Cd38に特異的な二環式ペプチドリガンド

Country Status (6)

Country Link
US (1) US20220133733A1 (enExample)
EP (1) EP3911366A1 (enExample)
JP (1) JP2022517399A (enExample)
CN (1) CN113597317A (enExample)
GB (1) GB201900530D0 (enExample)
WO (1) WO2020148530A1 (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107148425B (zh) 2014-10-29 2021-08-03 拜斯科阿迪有限公司 对mt1-mmp特异性的双环肽配体
EP3645549A1 (en) 2017-06-26 2020-05-06 BicycleRD Limited Bicyclic peptide ligands with detectable moieties and uses thereof
JP7670481B2 (ja) 2017-08-04 2025-04-30 バイスクルテクス・リミテッド Cd137に対して特異的な二環式ペプチドリガンド
CN111902429A (zh) 2018-02-23 2020-11-06 拜斯科技术开发有限公司 多聚体双环肽配体
IL279489B2 (en) 2018-06-22 2025-10-01 Bicycletx Ltd Bicyclic peptide ligands specific for nectin-4, a drug conjugate containing the peptide ligands and a pharmaceutical composition containing the drug conjugate
GB201820295D0 (en) 2018-12-13 2019-01-30 Bicyclerd Ltd Bicyclic peptide ligands specific for MT1-MMP
GB201820325D0 (en) 2018-12-13 2019-01-30 Bicyclerd Ltd Bicyclic peptide ligands specific for psma
GB201820288D0 (en) 2018-12-13 2019-01-30 Bicycle Tx Ltd Bicycle peptide ligaands specific for MT1-MMP
WO2020128527A1 (en) 2018-12-21 2020-06-25 Bicyclerd Limited Bicyclic peptide ligands specific for pd-l1
US12492224B2 (en) 2018-12-21 2025-12-09 Bicycletx Limited Bicyclic peptide ligands specific for PD-L1
GB201900529D0 (en) 2019-01-15 2019-03-06 Bicycletx Ltd Bicyclic peptide ligands specific for CD38
TWI860386B (zh) 2019-07-30 2024-11-01 英商拜西可泰克斯有限公司 異質雙環肽複合物
AU2021322934A1 (en) 2020-08-03 2023-03-30 Bicycletx Limited Peptide-based linkers
GB202016331D0 (en) * 2020-10-15 2020-12-02 Bicyclerd Ltd Bicyclic peptide ligand drug conjugates
CN118388598A (zh) * 2024-04-22 2024-07-26 苏州大学附属第一医院 标记前体、探针及其制备方法和应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004052404A2 (en) * 2002-12-12 2004-06-24 Tel Aviv University Future Technology Development L.P. Glycogen synthase kinase-3 inhibitors
EP1452868A2 (en) 2003-02-27 2004-09-01 Pepscan Systems B.V. Method for selecting a candidate drug compound
KR20140066259A (ko) 2004-02-06 2014-05-30 모르포시스 아게 항-cd38 인간 항체 및 그의 용도
WO2006078161A1 (en) 2005-01-24 2006-07-27 Pepscan Systems B.V. Binding compounds, immunogenic compounds and peptidomimetics
JP5225069B2 (ja) * 2005-03-23 2013-07-03 ゲンマブ エー/エス 多発性骨髄腫の治療のためのcd38に対する抗体
EP2653545A1 (en) 2008-02-05 2013-10-23 Bicycle Therapeutics Limited Methods and compositions
JP6807831B2 (ja) * 2014-05-21 2021-01-06 エントラーダ セラピューティクス,インコーポレイテッド 細胞膜透過性ペプチド、並びにこの作製方法及び使用方法
CN107148425B (zh) 2014-10-29 2021-08-03 拜斯科阿迪有限公司 对mt1-mmp特异性的双环肽配体
CN107810190A (zh) * 2015-04-28 2018-03-16 洛桑联邦政府综合工科学校(Epfl) 酶活化因子XII (FXIIa)的新型抑制剂
EP3645549A1 (en) * 2017-06-26 2020-05-06 BicycleRD Limited Bicyclic peptide ligands with detectable moieties and uses thereof
GB201810320D0 (en) * 2018-06-22 2018-08-08 Bicycletx Ltd Peptide ligands for binding to CD38

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